Gene: Gck (glucokinase) Rattus norvegicus
Symbol: Gck
Name: glucokinase
Description: ENCODES a protein that exhibits ADP binding; ATP binding; glucokinase activity; INVOLVED IN carbohydrate phosphorylation; cellular glucose homeostasis; cellular response to glucose starvation; PARTICIPATES IN glycogen biosynthetic pathway; glycogen metabolic pathway; glycolysis pathway; ASSOCIATED WITH decreased circulating glucose level; increased circulating free fatty acid level; increased circulating triglyceride level; ASSOCIATED WITH Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Fatty Liver; FOUND IN actin filament; basal cortex; cell cortex; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: glucokinase variant 3; GLUKA; hexokinase type IV; hexokinase-4; hexokinase-D; HK IV; HK4; RNGK2
Orthologs:
Is Marker For: QTLs:   Pancm5   Niddm37  
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
RGSC Genome Assembly v6.01486,149,146 - 86,191,576-NCBI
Rat Cytogenetic Map14q21 NCBI
RGSC Genome Assembly v5.01486,832,735 - 86,875,295-NCBI
RGSC Genome Assembly v3.41486,572,518 - 86,587,723-NCBI
Rat Celera Assembly1479,669,432 - 79,710,739-NCBI
Genome Assembly 3.11486,591,662 - 86,606,868-NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gck
Entrez Gene
Ensembl Gene
Genome Browser
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 2670
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2014-10-07
Status: ACTIVE