Gene: Gck (glucokinase) Rattus norvegicus
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Symbol: Gck
Name: glucokinase
Description: ENCODES a protein that exhibits ADP binding; ATP binding; glucokinase activity; INVOLVED IN carbohydrate phosphorylation; cellular glucose homeostasis; cellular response to glucose starvation; PARTICIPATES IN glycogen biosynthetic pathway; glycogen metabolic pathway; glycolysis pathway; ASSOCIATED WITH decreased circulating glucose level; increased circulating free fatty acid level; increased circulating triglyceride level; ASSOCIATED WITH Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Fatty Liver; FOUND IN actin filament; basal cortex; cell cortex; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GLK; glucokinase variant 3; GLUKA; hexokinase type IV; hexokinase-4; hexokinase-D; HK IV; HK4; RNGK2
Orthologs:
Homo sapiens : GCK (glucokinase)  HGNC
Mus musculus : Gck (glucokinase)  MGI
more info ...
Is Marker For: QTLs:   Pancm5   Niddm37  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01486,149,146 - 86,191,589 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01486,832,735 - 86,875,295 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41486,572,518 - 86,587,723 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11486,591,662 - 86,606,868 (-)NCBI
Celera1479,669,432 - 79,710,739 (-)NCBI
Cytogenetic Map14q21NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated
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Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gck
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
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RGD Object Information
RGD ID: 2670
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-08-09
Status: ACTIVE