| (+)-pilocarpine | decreases expression | EXP | | 6480464 | Pilocarpine results in decreased expression of OPRM1 protein | CTD | PMID:17919468 |
| (3,4-dihydroxyphenyl)acetic acid | multiple interactions | EXP | | 6480464 | [beta-funaltrexamine binds to and results in decreased activity of OPRM1 protein] inhibits the reaction [Morphine results in increased abundance of 3,4-Dihydroxyphenylacetic Acid] | CTD | PMID:8884884 |
| (R)-noradrenaline | multiple interactions | EXP | | 6480464 | [Dextromethorphan binds to OPRM1 protein] which results in decreased uptake of Norepinephrine; more ... | CTD | PMID:7562497 |
| (S)-amphetamine | affects expression | EXP | | 6480464 | Dextroamphetamine affects the expression of OPRM1 mRNA | CTD | PMID:12629526 |
| (S)-nicotine | multiple interactions | ISO | RGD:1551432 | 6480464 | [beta-funaltrexamine binds to and results in decreased activity of OPRM1 protein] which results in decreased susceptibility to Nicotine | CTD | PMID:15778877 |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:1551432 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of OPRM1 mRNA | CTD | PMID:19465110 |
| 3',5'-cyclic AMP | multiple interactions | ISO | RGD:737513 | 6480464 | [chlornaltrexamine binds to and results in decreased activity of OPRM1 protein] which results in increased expression of Cyclic AMP; more ... | CTD | PMID:11413242 |
| 5-aza-2'-deoxycytidine | affects methylation | ISO | RGD:1551432 | 6480464 | decitabine affects the methylation of OPRM1 promoter | CTD | PMID:17452465 |
| 5-aza-2'-deoxycytidine | multiple interactions | ISO | RGD:1551432 | 6480464 | [decitabine affects the methylation of OPRM1 promoter] which affects the expression of OPRM1 mRNA | CTD | PMID:17452465 PMID:17452465 |
| 5-aza-2'-deoxycytidine | multiple interactions | ISO | RGD:1551432 | 6480464 | [decitabine affects the methylation of OPRM1 promoter] which affects the expression of OPRM1 mRNA | CTD | PMID:17452465 |
| all-trans-retinol | affects expression | EXP | | 6480464 | Vitamin A affects the expression of OPRM1 mRNA; more ... | CTD | PMID:17289162 |
| ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of OPRM1 mRNA | CTD | PMID:16483693 |
| benzo[a]pyrene | decreases expression | ISO | RGD:1551432 | 6480464 | Benzo(a)pyrene results in decreased expression of OPRM1 mRNA | CTD | PMID:19428949 |
| buprenorphine | multiple interactions | ISO | RGD:737513 | 6480464 | Buprenorphine binds to and results in increased activity of OPRM1 protein | CTD | PMID:16010532 |
| buprenorphine | affects binding | EXP | | 6480464 | Buprenorphine binds to OPRM1 protein | CTD | PMID:7562497 |
| butan-1-ol | multiple interactions | EXP | | 6480464 | [1-Butanol inhibits the reaction [PLD2 protein results in increased chemical synthesis of Phosphatidic Acids]] affects the reaction [PENK protein binds to and results in increased activity of OPRM1 protein] | CTD | PMID:14720217 |
| butorphanol | affects activity | ISO | RGD:737513 | 6480464 | Butorphanol affects the activity of OPRM1 protein | CTD | PMID:17909753 |
| butorphanol | affects activity | EXP | | 6480464 | Butorphanol affects the activity of OPRM1 protein | CTD | PMID:17909753 |
| cadmium atom | multiple interactions | EXP | | 6480464 | Cadmium inhibits the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to OPRM1 protein] | CTD | PMID:2162496 |
| calcium atom | multiple interactions | ISO | RGD:1551432 | 6480464 | [Tetradecanoylphorbol Acetate co-treated with Calcium] inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]] | CTD | PMID:18652891 |
| calcium(0) | multiple interactions | ISO | RGD:1551432 | 6480464 | [Tetradecanoylphorbol Acetate co-treated with Calcium] inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]] | CTD | PMID:18652891 |
| capsaicin | multiple interactions | ISO | RGD:737513 | 6480464 | Capsaicin inhibits the reaction [carfentanil binds to OPRM1 protein] | CTD | PMID:12406535 |
| carfentanyl | multiple interactions | ISO | RGD:737513 | 6480464 | Capsaicin inhibits the reaction [carfentanil binds to OPRM1 protein] | CTD | PMID:12406535 |
| carfentanyl | multiple interactions | ISO | RGD:737513 | 6480464 | Cocaine affects the reaction [carfentanil binds to OPRM1 protein] | CTD | PMID:15953495 |
| clonidine | multiple interactions | EXP | | 6480464 | [Naloxone binds to and results in decreased activity of OPRM1 protein] which results in decreased susceptibility to Clonidine | CTD | PMID:8987795 |
| clonidine | increases response to substance | EXP | | 6480464 | OPRM1 results in increased susceptibility to Clonidine | CTD | PMID:8987795 |
| clonidine (amino form) | multiple interactions | EXP | | 6480464 | [Naloxone binds to and results in decreased activity of OPRM1 protein] which results in decreased susceptibility to Clonidine | CTD | PMID:8987795 |
| clonidine (amino form) | increases response to substance | EXP | | 6480464 | OPRM1 results in increased susceptibility to Clonidine | CTD | PMID:8987795 |
| clonidine (imino form) | multiple interactions | EXP | | 6480464 | [Naloxone binds to and results in decreased activity of OPRM1 protein] which results in decreased susceptibility to Clonidine | CTD | PMID:8987795 |
| clonidine (imino form) | increases response to substance | EXP | | 6480464 | OPRM1 results in increased susceptibility to Clonidine | CTD | PMID:8987795 |
| cocaine | multiple interactions | ISO | RGD:737513 | 6480464 | Cocaine affects the reaction [carfentanil binds to OPRM1 protein] | CTD | PMID:15953495 |
| cocaine | affects expression | EXP | | 6480464 | Cocaine affects the expression of OPRM1 mRNA | CTD | PMID:18990547 PMID:15950784 |
| cocaine | affects expression | EXP | | 6480464 | Cocaine affects the expression of OPRM1 protein | CTD | PMID:10891866 |
| cocaine | decreases expression | EXP | | 6480464 | Cocaine results in decreased expression of OPRM1 mRNA | CTD | PMID:12128154 |
| cocaine | multiple interactions | EXP | | 6480464 | [CTAP octapeptide binds to and results in decreased activity of OPRM1 protein] inhibits the reaction [POMC protein results in increased susceptibility to Cocaine]; more ... | CTD | PMID:19279569 |
| cocaine | affects expression | EXP | | 6480464 | Cocaine affects the expression of OPRM1 mRNA | CTD | PMID:15950784 PMID:18990547 |
| cocaine | decreases response to substance | ISO | RGD:1551432 | 6480464 | OPRM1 mutant form results in decreased susceptibility to Cocaine | CTD | PMID:15664692 |
| cocaine | multiple interactions | ISO | RGD:1551432 | 6480464 | PDYN protein affects the reaction [Cocaine results in increased activity of OPRM1 protein] | CTD | PMID:17532787 |
| cocaine | decreases response to substance | ISO | RGD:1551432 | 6480464 | OPRM1 gene mutant form results in decreased susceptibility to Cocaine | CTD | PMID:16893609 |
| cocaine | affects response to substance | ISO | RGD:1551432 | 6480464 | OPRM1 protein affects the susceptibility to Cocaine | CTD | PMID:10803207 |
| cocaine | increases response to substance | ISO | RGD:737513 | 6480464 | OPRM1 gene SNP results in increased susceptibility to Cocaine | CTD | PMID:12815747 |
| cocaine | increases activity | ISO | RGD:1551432 | 6480464 | Cocaine results in increased activity of OPRM1 protein | CTD | PMID:17532787 |
| codeine | affects binding | EXP | | 6480464 | Codeine binds to OPRM1 protein | CTD | PMID:7562497 |
| copper atom | multiple interactions | EXP | | 6480464 | Copper inhibits the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to OPRM1 protein] | CTD | PMID:2162496 |
| copper(0) | multiple interactions | EXP | | 6480464 | Copper inhibits the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to OPRM1 protein] | CTD | PMID:2162496 |
| cycloheximide | multiple interactions | ISO | RGD:737513 | 6480464 | Cycloheximide inhibits the reaction [Tetrahydrocannabinol results in increased expression of OPRM1 mRNA] | CTD | PMID:16434616 |
| Delta(9)-tetrahydrocannabinol | multiple interactions | EXP | | 6480464 | Tetrahydrocannabinol promotes the reaction [Naloxone inhibits the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to and results in increased activity of OPRM1 protein]] | CTD | PMID:16489449 |
| Delta(9)-tetrahydrocannabinol | multiple interactions | EXP | | 6480464 | Tetrahydrocannabinol promotes the reaction [Guanosine Triphosphate binds to OPRM1 protein] | CTD | PMID:16823391 |
| Delta(9)-tetrahydrocannabinol | increases expression | ISO | RGD:737513 | 6480464 | Tetrahydrocannabinol results in increased expression of OPRM1 mRNA | CTD | PMID:16434616 |
| Delta(9)-tetrahydrocannabinol | multiple interactions | ISO | RGD:737513 | 6480464 | IL4 protein mutant form inhibits the reaction [Tetrahydrocannabinol results in increased expression of OPRM1 mRNA]; more ... | CTD | PMID:16434616 |
| Delta(9)-tetrahydrocannabinol | affects response to substance | ISO | RGD:1551432 | 6480464 | OPRM1 affects the susceptibility to Tetrahydrocannabinol | CTD | PMID:11826143 |
| dextromethorphan | multiple interactions | EXP | | 6480464 | [Dextromethorphan binds to OPRM1 protein] which results in decreased uptake of Serotonin; more ... | CTD | PMID:7562497 |
| dextromethorphan | affects binding | EXP | | 6480464 | Dextromethorphan binds to OPRM1 protein | CTD | PMID:7562497 |
| dextropropoxyphene | multiple interactions | EXP | | 6480464 | [Dextropropoxyphene binds to OPRM1 protein] which results in decreased uptake of Norepinephrine; more ... | CTD | PMID:7562497 |
| dextropropoxyphene | affects binding | EXP | | 6480464 | Dextropropoxyphene binds to OPRM1 protein | CTD | PMID:7562497 |
| dextrorphan | multiple interactions | EXP | | 6480464 | [Dextrorphan binds to OPRM1 protein] which results in decreased uptake of Norepinephrine; more ... | CTD | PMID:7562497 |
| dextrorphan | affects binding | EXP | | 6480464 | Dextrorphan binds to OPRM1 protein | CTD | PMID:7562497 |
| diisopropyl fluorophosphate | affects response to substance | ISO | RGD:1551432 | 6480464 | OPRM1 affects the susceptibility to Isoflurophate | CTD | PMID:15378609 PMID:15800401 |
| diisopropyl fluorophosphate | affects response to substance | ISO | RGD:1551432 | 6480464 | OPRM1 affects the susceptibility to Isoflurophate | CTD | PMID:15800401 PMID:15378609 |
| ethanol | increases response to substance | ISO | RGD:737513 | 6480464 | OPRM1 gene SNP results in increased susceptibility to Ethanol | CTD | PMID:12815747 |
| ethanol | affects response to substance | ISO | RGD:1551432 | 6480464 | OPRM1 protein affects the susceptibility to Ethanol | CTD | PMID:10803207 |
| fentanyl | increases phosphorylation | ISO | RGD:1551432 | 6480464 | Fentanyl results in increased phosphorylation of OPRM1 protein | CTD | PMID:17240843 |
| fentanyl | increases phosphorylation | ISO | RGD:1551432 | 6480464 | Fentanyl results in increased phosphorylation of OPRM1 protein | CTD | PMID:17240843 PMID:21957251 |
| fluoxetine | multiple interactions | ISO | RGD:1551432 | 6480464 | Fluoxetine inhibits the reaction [Methamphetamine results in decreased expression of OPRM1 mRNA]; more ... | CTD | PMID:21886566 |
| fluoxetine | increases expression | EXP | | 6480464 | Fluoxetine results in increased expression of OPRM1 protein | CTD | PMID:16484055 |
| gamma-aminobutyric acid | decreases secretion | ISO | RGD:1551432 | 6480464 | OPRM1 protein mutant form results in decreased secretion of gamma-Aminobutyric Acid | CTD | PMID:20203187 |
| GTP | affects binding | EXP | | 6480464 | Guanosine Triphosphate binds to OPRM1 protein | CTD | PMID:16823391 |
| GTP | multiple interactions | EXP | | 6480464 | Tetrahydrocannabinol promotes the reaction [Guanosine Triphosphate binds to OPRM1 protein] | CTD | PMID:16823391 |
| guanosine 5'-[gamma-thio]triphosphate | multiple interactions | ISO | RGD:737513 | 6480464 | [chlornaltrexamine binds to and results in decreased activity of OPRM1 protein] which affects the localization of Guanosine 5'-O-(3-Thiotriphosphate); more ... | CTD | PMID:11413242 |
| guanosine 5'-[gamma-thio]triphosphate | multiple interactions | ISO | RGD:1551432 | 6480464 | ADORA2A protein affects the reaction [[Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to OPRM1 protein] which results in increased activity of Guanosine 5'-O-(3-Thiotriphosphate)] | CTD | PMID:14756803 |
| haloperidol | multiple interactions | ISO | RGD:1551432 | 6480464 | OPRM1 protein inhibits the reaction [Haloperidol inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]] | CTD | PMID:20184921 |
| homovanillic acid | multiple interactions | EXP | | 6480464 | [beta-funaltrexamine binds to and results in decreased activity of OPRM1 protein] inhibits the reaction [Morphine results in increased abundance of Homovanillic Acid] | CTD | PMID:8884884 |
| hydrocodone | affects binding | EXP | | 6480464 | Hydrocodone binds to OPRM1 protein | CTD | PMID:7562497 |
| lithium chloride | decreases expression | EXP | | 6480464 | Lithium Chloride results in decreased expression of OPRM1 protein | CTD | PMID:17919468 |
| magnesium atom | multiple interactions | EXP | | 6480464 | Zinc inhibits the reaction [Magnesium promotes the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to OPRM1 protein]] | CTD | PMID:2162496 |
| manganese atom | multiple interactions | EXP | | 6480464 | Manganese promotes the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to OPRM1 protein]; more ... | CTD | PMID:2162496 |
| manganese(0) | multiple interactions | EXP | | 6480464 | Manganese promotes the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to OPRM1 protein]; more ... | CTD | PMID:2162496 |
| mercury atom | multiple interactions | EXP | | 6480464 | Mercury inhibits the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to OPRM1 protein] | CTD | PMID:2162496 |
| mercury(0) | multiple interactions | EXP | | 6480464 | Mercury inhibits the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to OPRM1 protein] | CTD | PMID:2162496 |
| methadone | multiple interactions | EXP | | 6480464 | [Methadone binds to OPRM1 protein] which results in decreased uptake of Norepinephrine; more ... | CTD | PMID:7562497 |
| methadone | affects binding | EXP | | 6480464 | Methadone binds to OPRM1 protein | CTD | PMID:7562497 |
| methamphetamine | increases response to substance | ISO | RGD:737513 | 6480464 | OPRM1 gene SNP results in increased susceptibility to Methamphetamine | CTD | PMID:16402083 |
| methamphetamine | multiple interactions | ISO | RGD:1551432 | 6480464 | OPRM1 protein inhibits the reaction [Haloperidol inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]] | CTD | PMID:20184921 |
| methamphetamine | decreases expression | ISO | RGD:1551432 | 6480464 | Methamphetamine results in decreased expression of OPRM1 mRNA; more ... | CTD | PMID:21886566 |
| methamphetamine | multiple interactions | ISO | RGD:1551432 | 6480464 | Fluoxetine inhibits the reaction [Methamphetamine results in decreased expression of OPRM1 protein]; more ... | CTD | PMID:21886566 |
| methamphetamine | increases expression | EXP | | 6480464 | Methamphetamine results in increased expression of OPRM1 mRNA | CTD | PMID:15644446 |
| methamphetamine | multiple interactions | EXP | | 6480464 | [CTAP octapeptide binds to and results in decreased activity of OPRM1 protein] which results in decreased susceptibility to Methamphetamine | CTD | PMID:20298714 |
| morphine | multiple interactions | ISO | RGD:1551432 | 6480464 | Morphine promotes the reaction [OPRM1 protein binds to PRKCG protein] | CTD | PMID:18652891 PMID:21235400 |
| morphine | increases phosphorylation | ISO | RGD:1551432 | 6480464 | Morphine results in increased phosphorylation of OPRM1 protein | CTD | PMID:18652891 PMID:21957251 |
| morphine | multiple interactions | ISO | RGD:1551432 | 6480464 | Naloxone inhibits the reaction [Morphine results in increased phosphorylation of OPRM1 protein] | CTD | PMID:21957251 |
| morphine | increases expression | ISO | RGD:1551432 | 6480464 | Morphine results in increased expression of OPRM1 protein | CTD | PMID:21957251 |
| morphine | increases phosphorylation | ISO | RGD:1551432 | 6480464 | Morphine results in increased phosphorylation of OPRM1 protein | CTD | PMID:21957251 |
| morphine | affects binding | EXP | | 6480464 | Morphine binds to OPRM1 protein | CTD | PMID:7562497 |
| morphine | multiple interactions | ISO | RGD:1551432 | 6480464 | Dizocilpine Maleate inhibits the reaction [Morphine promotes the reaction [OPRM1 protein binds to PRKCA protein]]; more ... | CTD | PMID:18652891 |
| morphine | affects activity | ISO | RGD:1551432 | 6480464 | OPRM1 affects the activity of Morphine | CTD | PMID:12213227 |
| morphine | multiple interactions | EXP | | 6480464 | [naloxonazine binds to and results in decreased activity of OPRM1 protein] which affects the susceptibility to Morphine | CTD | PMID:9264103 |
| morphine | multiple interactions | ISO | RGD:1551432 | 6480464 | [Zymosan co-treated with Morphine] results in increased expression of OPRM1 mRNA | CTD | PMID:15979727 |
| morphine | multiple interactions | EXP | | 6480464 | [beta-funaltrexamine binds to and results in decreased activity of OPRM1 protein] inhibits the reaction [Morphine results in increased abundance of 3,4-Dihydroxyphenylacetic Acid]; more ... | CTD | PMID:8884884 |
| morphine | affects response to substance | ISO | RGD:1551432 | 6480464 | OPRM1 protein affects the susceptibility to Morphine | CTD | PMID:10803207 |
| morphine | multiple interactions | ISO | RGD:1551432 | 6480464 | OPRM1 gene mutant form inhibits the reaction [Morphine results in decreased expression of IFNG]; more ... | CTD | PMID:11590188 |
| morphine | multiple interactions | ISO | RGD:1551432 | 6480464 | [Morphine results in increased activity of OPRM1 protein] which results in increased phosphorylation of GRIN1 protein; more ... | CTD | PMID:17996026 |
| morphine | increases activity | ISO | RGD:1551432 | 6480464 | Morphine results in increased activity of OPRM1 protein | CTD | PMID:17996026 |
| morphine | multiple interactions | ISO | RGD:1551432 | 6480464 | Morphine binds to and results in increased activity of OPRM1 protein; more ... | CTD | PMID:11272841 |
| morphine | multiple interactions | ISO | RGD:737513 | 6480464 | OPRM1 protein affects the reaction [Morphine results in decreased secretion of FGF2 protein] | CTD | PMID:20564181 |
| morphine | decreases response to substance | ISO | RGD:737513 | 6480464 | OPRM1 exon SNP results in decreased susceptibility to Morphine | CTD | PMID:15504181 |
| morphine | multiple interactions | ISO | RGD:737513 | 6480464 | [[Naloxone binds to and results in decreased activity of OPRM1 protein] which co-treated with Morphine] results in increased expression of Cyclic AMP; more ... | CTD | PMID:11413242 |
| morphine | multiple interactions | ISO | RGD:737513 | 6480464 | Morphine binds to and results in increased activity of OPRM1 protein | CTD | PMID:17656655 |
| morphine | affects activity | ISO | RGD:737513 | 6480464 | Morphine affects the activity of OPRM1 protein | CTD | PMID:11106302 |
| morphine | multiple interactions | ISO | RGD:737513 | 6480464 | [COMT gene SNP co-treated with OPRM1 gene SNP] affects the susceptibility to Morphine | CTD | PMID:21127283 |
| morphine | multiple interactions | ISO | RGD:1551432 | 6480464 | HINT1 affects the reaction [Morphine promotes the reaction [OPRM1 protein binds to MAPK3 protein]]; more ... | CTD | PMID:21235400 |
| N-ethyl-N-nitrosourea | increases mutagenesis | EXP | | 6480464 | Ethylnitrosourea results in increased mutagenesis of OPRM1 gene | CTD | PMID:16495775 |
| naloxone | multiple interactions | ISO | RGD:737513 | 6480464 | [[Naloxone binds to and results in decreased activity of OPRM1 protein] which co-treated with Morphine] results in increased expression of Cyclic AMP | CTD | PMID:11413242 |
| naloxone | multiple interactions | ISO | RGD:1551432 | 6480464 | Naloxone inhibits the reaction [Morphine results in increased phosphorylation of OPRM1 protein] | CTD | PMID:21957251 |
| naloxone | affects binding | EXP | | 6480464 | Naloxone binds to OPRM1 protein | CTD | PMID:7562497 |
| naloxone | multiple interactions | EXP | | 6480464 | Naloxone binds to and results in decreased activity of OPRM1 protein | CTD | PMID:1528399 more ... |
| naloxone | multiple interactions | EXP | | 6480464 | Naloxone binds to and results in decreased activity of OPRM1 protein | CTD | PMID:8383026 more ... |
| naloxone | multiple interactions | EXP | | 6480464 | Naloxone binds to and results in decreased activity of OPRM1 protein | CTD | PMID:9162281 more ... |
| naloxone | multiple interactions | EXP | | 6480464 | Naloxone binds to and results in decreased activity of OPRM1 protein | CTD | PMID:1528399 more ... |
| naloxone | multiple interactions | EXP | | 6480464 | Naloxone binds to and results in decreased activity of OPRM1 protein | CTD | PMID:1654493 more ... |
| naloxone | multiple interactions | EXP | | 6480464 | Naloxone binds to and results in decreased activity of OPRM1 protein | CTD | PMID:9162281 more ... |
| naloxone | multiple interactions | EXP | | 6480464 | Naloxone binds to and results in decreased activity of OPRM1 protein | CTD | PMID:8383026 more ... |
| naloxone | multiple interactions | EXP | | 6480464 | [Naloxone binds to and results in decreased activity of OPRM1 protein] which results in decreased susceptibility to Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; more ... | CTD | PMID:8987795 |
| naloxone | multiple interactions | EXP | | 6480464 | Cannabidiol promotes the reaction [Naloxone inhibits the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to and results in increased activity of OPRM1 protein]]; more ... | CTD | PMID:16489449 |
| naltrexone | multiple interactions | ISO | RGD:737513 | 6480464 | [[Naltrexone binds to and results in decreased activity of OPRM1 protein] which co-treated with Morphine] results in increased expression of Cyclic AMP | CTD | PMID:11413242 |
| naltrexone | affects binding | EXP | | 6480464 | Naltrexone binds to OPRM1 protein | CTD | PMID:7562497 |
| naltrexone | affects response to substance | ISO | RGD:737513 | 6480464 | OPRM1 affects the susceptibility to Naltrexone | CTD | PMID:18250251 |
| oxycodone | affects binding | EXP | | 6480464 | Oxycodone binds to OPRM1 protein | CTD | PMID:7562497 |
| phenytoin | multiple interactions | ISO | RGD:1551432 | 6480464 | [cyprodime binds to and results in decreased activity of OPRM1 protein] which results in decreased susceptibility to Phenytoin | CTD | PMID:7870991 |
| phorbol 13-acetate 12-myristate | increases expression | ISO | RGD:737513 | 6480464 | Tetradecanoylphorbol Acetate results in increased expression of OPRM1 mRNA | CTD | PMID:11901219 |
| phorbol 13-acetate 12-myristate | multiple interactions | ISO | RGD:1551432 | 6480464 | [Tetradecanoylphorbol Acetate co-treated with Calcium] inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]]; more ... | CTD | PMID:18652891 |
| phorbol 13-acetate 12-myristate | multiple interactions | ISO | RGD:737513 | 6480464 | Sulfasalazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of OPRM1 mRNA] | CTD | PMID:11901219 |
| serotonin | multiple interactions | EXP | | 6480464 | [Dextromethorphan binds to OPRM1 protein] which results in decreased uptake of Serotonin; more ... | CTD | PMID:7562497 |
| sulfasalazine | multiple interactions | ISO | RGD:737513 | 6480464 | Sulfasalazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of OPRM1 mRNA]; more ... | CTD | PMID:11901219 |
| thioglycolic acid | affects response to substance | EXP | | 6480464 | OPRM1 exon affects the susceptibility to 2-mercaptoacetate | CTD | PMID:10802031 |
| trichostatin A | affects expression | ISO | RGD:1551432 | 6480464 | trichostatin A affects the expression of OPRM1 mRNA | CTD | PMID:17452465 |
| valproic acid | affects expression | ISO | RGD:1551432 | 6480464 | Valproic Acid affects the expression of OPRM1 mRNA | CTD | PMID:17452465 |
| zinc atom | multiple interactions | ISO | RGD:1551432 | 6480464 | RGS17 protein affects the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]]; more ... | CTD | PMID:18652891 |
| zinc atom | multiple interactions | EXP | | 6480464 | Zinc inhibits the reaction [Magnesium promotes the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to OPRM1 protein]]; more ... | CTD | PMID:2162496 |
| zinc atom | multiple interactions | ISO | RGD:1551432 | 6480464 | Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein] | CTD | PMID:18652891 PMID:21235400 |
| zinc atom | multiple interactions | ISO | RGD:1551432 | 6480464 | calphostin complex inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein binds to RAF1 protein]]; more ... | CTD | PMID:21235400 |
| zinc(0) | multiple interactions | ISO | RGD:1551432 | 6480464 | RGS17 protein affects the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]]; more ... | CTD | PMID:18652891 |
| zinc(0) | multiple interactions | ISO | RGD:1551432 | 6480464 | Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein] | CTD | PMID:18652891 PMID:21235400 |
| zinc(0) | multiple interactions | EXP | | 6480464 | Zinc inhibits the reaction [Magnesium promotes the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to OPRM1 protein]]; more ... | CTD | PMID:2162496 |
| zinc(0) | multiple interactions | ISO | RGD:1551432 | 6480464 | calphostin complex inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein binds to RAF1 protein]]; more ... | CTD | PMID:21235400 |