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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3234
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Oprm1
Name: opioid receptor, mu 1
Acc ID: CHEBI:7457
Term: Nalmefene
Definition: A morphinane alkaloid that has formula C21H25NO3.
Chemical ID: MESH:C038981
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Oprm1multiple interactionsISOOPRM1 (Homo sapiens)6480464CTD[nalmefene binds to and results in decreased activity of OPRM1 protein] which results in increased expression of Cyclic AMP; nalmefene binds to and results in decreased activity of OPRM1 proteinPMID:11413242 PMID:9862779
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