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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of canonical NF-kappaB signal transduction
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Accession:GO:0043123 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of a canonical NF-kappaB signaling cascade.
Synonyms:exact_synonym: positive regulation of I-kappaB kinase/NF-kappaB signaling
 narrow_synonym: stimulation of I-kappaB kinase/NF-kappaB cascade
 related_synonym: activation of I-kappaB kinase/NF-kappaB cascade;   positive regulation of I-kappaB kinase/NF-kappaB cascade;   up regulation of I-kappaB kinase/NF-kappaB cascade;   upregulation of I-kappaB kinase/NF-kappaB cascade
 only_in_taxon: NCBITaxon:6072 ! Eumetazoa


show annotations for term's descendants           Sort by:
positive regulation of canonical NF-kappaB signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18025176) Ensembl
MGI		 PMID:18025176 GO_REF:0000107 NCBI chr 9:130,713,043...130,887,675
Ensembl chr 9:130,713,043...130,887,675 		JBrowse link
G ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:18025176) MGI PMID:18025176 NCBI chr 1:179,099,330...179,229,677
Ensembl chr 1:179,099,330...179,229,684 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing involved_in
acts_upstream_of_or_within		 ISS
IEA
ISO		 (PMID:12087086), (PMID:14522956) UniProt
Ensembl
MGI		 PMID:12087086 PMID:14522956 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463 		JBrowse link
G AGT angiotensinogen acts_upstream_of_or_within ISO (PMID:19404405) MGI PMID:19404405 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AJUBA ajuba LIM protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:22,971,177...22,982,551
Ensembl chr14:22,971,177...22,982,551 		JBrowse link
G AKAP13 A-kinase anchoring protein 13 involved_in IMP
IEA
IBA		 (PMID:23090968) UniProt
TreeGrafter
GO_Central		 PMID:23090968 GO_REF:0000033 GO_REF:0000118 NCBI chr15:85,380,603...85,749,358
Ensembl chr15:85,380,571...85,749,358 		JBrowse link
G ALPK1 alpha kinase 1 involved_in IDA (PMID:28222186), (PMID:28877472), (PMID:30111836) UniProt PMID:28222186 PMID:28877472 PMID:30111836 NCBI chr 4:112,297,369...112,442,621
Ensembl chr 4:112,285,509...112,442,621 		JBrowse link
G ANKRD17 ankyrin repeat domain 17 involved_in IDA (PMID:22328336) UniProt PMID:22328336 NCBI chr 4:73,073,376...73,258,798
Ensembl chr 4:73,073,376...73,258,798 		JBrowse link
G APOL3 apolipoprotein L3 involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr22:36,140,323...36,166,177
Ensembl chr22:36,140,329...36,166,177 		JBrowse link
G ATP2C1 ATPase secretory pathway Ca2+ transporting 1 involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr 3:130,850,595...131,016,712
Ensembl chr 3:130,850,595...131,016,712 		JBrowse link
G BCL10 BCL10 immune signaling adaptor involved_in IDA
IEP		 (PMID:18287044), (PMID:27777308)
(PMID:12761501)		 UniProt PMID:12761501 PMID:18287044 PMID:27777308 NCBI chr 1:85,265,776...85,276,632
Ensembl chr 1:85,265,776...85,276,632 		JBrowse link
G BIRC2 baculoviral IAP repeat containing 2 involved_in IEP
IEA		 (PMID:12761501) UniProt
Ensembl		 PMID:12761501 GO_REF:0000107 NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,211...102,378,670 		JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 involved_in TAS (PMID:20651737) UniProt PMID:20651737 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403 		JBrowse link
G BRD4 bromodomain containing 4 involved_in IDA (PMID:19103749) UniProt PMID:19103749 NCBI chr19:15,235,519...15,332,539
Ensembl chr19:15,235,519...15,332,545 		JBrowse link
G BST2 bone marrow stromal cell antigen 2 involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr19:17,402,939...17,405,630
Ensembl chr19:17,402,939...17,405,630 		JBrowse link
G C18orf32 chromosome 18 open reading frame 32 involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr18:49,477,243...49,487,234
Ensembl chr18:49,477,243...49,487,252 		JBrowse link
G CANT1 calcium activated nucleotidase 1 involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr17:78,991,716...79,009,764
Ensembl chr17:78,991,716...79,009,867 		JBrowse link
G CARD11 caspase recruitment domain family member 11 involved_in IEA
IMP
ISS
IBA		 (PMID:12154360) Ensembl
UniProt
TreeGrafter
GO_Central		 PMID:12154360 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:2,906,142...3,043,867
Ensembl chr 7:2,906,142...3,044,228 		JBrowse link
G CARD16 caspase recruitment domain family member 16 involved_in IDA (PMID:15383541) UniProt PMID:15383541 NCBI chr11:105,041,563...105,045,335
Ensembl chr11:105,041,326...105,101,431 		JBrowse link
G CARD9 caspase recruitment domain family member 9 involved_in IEP
IBA
IDA		 (PMID:11053425) UniProt
GO_Central		 PMID:11053425 GO_REF:0000033 NCBI chr 9:136,363,956...136,373,669
Ensembl chr 9:136,363,956...136,373,681 		JBrowse link
G CASP1 caspase 1 involved_in IEP
IMP		 (PMID:12761501)
(PMID:15383541)		 UniProt PMID:12761501 PMID:15383541 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250 		JBrowse link
G CASP10 caspase 10 involved_in IMP (PMID:12884866) UniProt PMID:12884866 NCBI chr 2:201,183,141...201,229,406
Ensembl chr 2:201,182,872...201,229,428 		JBrowse link
G CASP8 caspase 8 involved_in IEP
IMP		 (PMID:12761501)
(PMID:12884866)		 UniProt PMID:12761501 PMID:12884866 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CAV1 caveolin 1 involved_in IMP (PMID:23319823) ARUK-UCL PMID:23319823 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179 		JBrowse link
G CC2D1A coiled-coil and C2 domain containing 1A involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr19:13,906,201...13,930,879
Ensembl chr19:13,906,201...13,930,879 		JBrowse link
G CCDC22 coiled-coil domain containing 22 involved_in IMP (PMID:23563313) UniProt PMID:23563313 NCBI chr  X:49,235,470...49,250,520
Ensembl chr  X:49,235,470...49,250,520 		JBrowse link
G CCL19 C-C motif chemokine ligand 19 involved_in IDA (PMID:15059845) BHF-UCL PMID:15059845 NCBI chr 9:34,689,570...34,691,276
Ensembl chr 9:34,689,570...34,691,276 		JBrowse link
G CCL21 C-C motif chemokine ligand 21 involved_in IDA (PMID:15059845) BHF-UCL PMID:15059845 NCBI chr 9:34,709,005...34,710,136
Ensembl chr 9:34,709,005...34,710,136 		JBrowse link
G CCR7 C-C motif chemokine receptor 7 involved_in IC (PMID:15059845) BHF-UCL PMID:15059845 NCBI chr17:40,553,769...40,565,472
Ensembl chr17:40,553,769...40,565,472 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) involved_in
acts_upstream_of_or_within		 IEA
IGI
ISO		 (PMID:20037584)
(PMID:16061696)		 Ensembl
ARUK-UCL
MGI		 PMID:16061696 PMID:20037584 GO_REF:0000107 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277 		JBrowse link
G CD4 CD4 molecule involved_in IDA (PMID:24942581) CAFA PMID:24942581 NCBI chr12:6,789,528...6,820,799
Ensembl chr12:6,786,858...6,820,799 		JBrowse link
G CD40 CD40 molecule involved_in IEP
IEA		 (PMID:12761501) UniProt
TreeGrafter		 PMID:12761501 GO_REF:0000118 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863 		JBrowse link
G CD74 CD74 molecule involved_in IDA (PMID:24942581) CAFA PMID:24942581 NCBI chr 5:150,401,639...150,412,910
Ensembl chr 5:150,401,637...150,412,969 		JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator involved_in IEP (PMID:12761501) UniProt PMID:12761501 NCBI chr 2:201,116,164...201,176,687
Ensembl chr 2:201,116,154...201,176,687 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex involved_in IMP
IDA		 (PMID:23487264)
(PMID:12656673)		 ARUK-UCL PMID:12656673 PMID:23487264 NCBI chr10:100,186,319...100,229,596
Ensembl chr10:100,188,300...100,229,596 		JBrowse link
G CLEC4D C-type lectin domain family 4 member D involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:8,513,503...8,531,696
Ensembl chr12:8,509,475...8,522,366 		JBrowse link
G CLEC6A C-type lectin domain containing 6A involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:8,455,962...8,478,330
Ensembl chr12:8,455,962...8,478,330 		JBrowse link
G CLEC7A C-type lectin domain containing 7A involved_in ISS UniProt GO_REF:0000024 NCBI chr12:10,116,777...10,130,304
Ensembl chr12:10,116,777...10,130,258 		JBrowse link
G CTH cystathionine gamma-lyase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:70,411,268...70,439,851
Ensembl chr 1:70,411,218...70,439,851 		JBrowse link
G CUL1 cullin 1 involved_in IDA (PMID:10644755) UniProt PMID:10644755 NCBI chr 7:148,697,756...148,801,110
Ensembl chr 7:148,697,914...148,801,110 		JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 involved_in ISS
IGI		 (PMID:10869418) ARUK-UCL PMID:10869418 GO_REF:0000024 NCBI chr16:57,372,490...57,385,044
Ensembl chr16:57,372,477...57,385,044 		JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 involved_in ISS
IEA		 ARUK-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:39,263,494...39,292,966
Ensembl chr 3:39,263,495...39,281,735 		JBrowse link
G CXXC5 CXXC finger protein 5 involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr 5:139,647,299...139,683,882
Ensembl chr 5:139,647,299...139,683,882 		JBrowse link
G DAB2IP DAB2 interacting protein involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:121,567,074...121,785,530
Ensembl chr 9:121,567,057...121,785,530 		JBrowse link
G DDX1 DEAD-box helicase 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:15,591,868...15,631,101
Ensembl chr 2:15,591,178...15,634,346 		JBrowse link
G DDX21 DExD-box helicase 21 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:68,956,170...68,985,068
Ensembl chr10:68,956,135...68,985,068 		JBrowse link
G DHX15 DEAH-box helicase 15 involved_in IDA (PMID:24990078) UniProt PMID:24990078 NCBI chr 4:24,527,475...24,584,554
Ensembl chr 4:24,517,441...24,584,554 		JBrowse link
G DHX36 DEAH-box helicase 36 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:154,272,546...154,324,487
Ensembl chr 3:154,272,546...154,324,487 		JBrowse link
G ECM1 extracellular matrix protein 1 involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr 1:150,508,109...150,513,789
Ensembl chr 1:150,508,062...150,513,789 		JBrowse link
G ECT2 epithelial cell transforming 2 involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr 3:172,750,726...172,829,265
Ensembl chr 3:172,750,682...172,821,474 		JBrowse link
G EDA ectodysplasin A involved_in
acts_upstream_of_or_within		 IEA
ISO
IDA		 (PMID:18689798)
(PMID:11039935)		 Ensembl
MGI
HGNC-UCL		 PMID:11039935 PMID:18689798 GO_REF:0000107 NCBI chr  X:69,616,113...70,039,472
Ensembl chr  X:69,616,067...70,039,472 		JBrowse link
G EDA2R ectodysplasin A2 receptor involved_in IEA
IBA
IDA		 (PMID:11039935) InterPro
TreeGrafter
GO_Central
HGNC-UCL		 PMID:11039935 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr  X:66,595,637...66,639,269
Ensembl chr  X:66,595,637...66,639,298 		JBrowse link
G EDAR ectodysplasin A receptor involved_in IEA
IBA		 InterPro
Ensembl
GO_Central
TreeGrafter		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:108,894,471...108,989,220
Ensembl chr 2:108,894,471...108,989,372 		JBrowse link
G EDN1 endothelin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G EDNRA endothelin receptor type A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:147,481,097...147,544,954
Ensembl chr 4:147,480,917...147,544,954 		JBrowse link
G EDNRB endothelin receptor type B involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:77,895,481...77,975,527
Ensembl chr13:77,895,481...77,975,529 		JBrowse link
G F2R coagulation factor II thrombin receptor involved_in IEP (PMID:12761501) UniProt PMID:12761501 NCBI chr 5:76,716,126...76,735,770
Ensembl chr 5:76,716,126...76,735,770 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IDA (PMID:11413129) UniProt PMID:11413129 NCBI chr 5:76,819,030...76,835,315
Ensembl chr 5:76,818,933...76,835,315 		JBrowse link
G FADD Fas associated via death domain involved_in IEP (PMID:12761501) UniProt PMID:12761501 NCBI chr11:70,203,296...70,207,390
Ensembl chr11:70,203,296...70,207,390 		JBrowse link
G FAIM Fas apoptotic inhibitory molecule ISO RGD PMID:15520226 RGD:1357927 NCBI chr 3:138,608,771...138,633,376
Ensembl chr 3:138,608,606...138,633,376 		JBrowse link
G FASLG Fas ligand involved_in IEP
IBA
IEA		 (PMID:12761501) UniProt
GO_Central
TreeGrafter		 PMID:12761501 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876 		JBrowse link
G FBXW11 F-box and WD repeat domain containing 11 involved_in IDA (PMID:10644755) UniProt PMID:10644755 NCBI chr 5:171,861,549...172,006,638
Ensembl chr 5:171,861,549...172,006,873 		JBrowse link
G FKBP1A FKBP prolyl isomerase 1A involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr20:1,368,978...1,393,054
Ensembl chr20:1,368,977...1,393,164 		JBrowse link
G FLNA filamin A involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr  X:154,348,531...154,374,634
Ensembl chr  X:154,348,524...154,374,634 		JBrowse link
G FLOT1 flotillin 1 involved_in IMP (PMID:23319823) ARUK-UCL PMID:23319823 NCBI chr 6:30,727,709...30,742,687
Ensembl chr 6:30,727,709...30,742,732 		JBrowse link
G FLOT2 flotillin 2 involved_in IMP (PMID:23319823) ARUK-UCL PMID:23319823 NCBI chr17:28,879,339...28,897,733
Ensembl chr17:28,879,335...28,897,733 		JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase involved_in IDA (PMID:23332158) UniProt PMID:23332158 NCBI chr12:6,534,517...6,538,371
Ensembl chr12:6,534,512...6,538,374 		JBrowse link
G GJA1 gap junction protein alpha 1 involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727 		JBrowse link
G GOLT1B golgi transport 1B involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr12:21,501,789...21,518,408
Ensembl chr12:21,501,781...21,518,408 		JBrowse link
G GPR89A G protein-coupled receptor 89A involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr 1:145,607,988...145,670,650
Ensembl chr 1:145,607,988...145,670,650
Ensembl chr 1:145,607,988...145,670,650 		JBrowse link
G GPR89B G protein-coupled receptor 89B involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr 1:147,928,420...148,025,934
Ensembl chr 1:147,928,393...147,993,592
Ensembl chr 1:147,928,393...147,993,592 		JBrowse link
G GPRC5B G protein-coupled receptor class C group 5 member B involved_in ISS CAFA GO_REF:0000024 NCBI chr16:19,856,691...19,885,634
Ensembl chr16:19,856,691...19,886,167 		JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 involved_in IDA (PMID:24942581) CAFA PMID:24942581 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848 		JBrowse link
G HMOX1 heme oxygenase 1 involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HTR2B 5-hydroxytryptamine receptor 2B involved_in IEP (PMID:12761501) UniProt PMID:12761501 NCBI chr 2:231,108,230...231,125,042
Ensembl chr 2:231,108,230...231,125,042 		JBrowse link
G IFIT5 interferon induced protein with tetratricopeptide repeats 5 involved_in IMP (PMID:26334375) UniProt PMID:26334375 NCBI chr10:89,414,568...89,420,997
Ensembl chr10:89,414,568...89,421,605 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta involved_in IMP
IDA		 (PMID:30337470)
(PMID:12656673), (PMID:9346484)		 UniProt PMID:9346484 PMID:12656673 PMID:30337470 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon involved_in IEP
IDA		 (PMID:12761501)
(PMID:10882136)		 UniProt
GO_Central		 PMID:10882136 PMID:12761501 NCBI chr 1:206,470,476...206,496,889
Ensembl chr 1:206,470,476...206,496,889 		JBrowse link
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma acts_upstream_of_or_within
involved_in		 IDA
IBA		 (PMID:17702576)
(PMID:18287044), (PMID:27777308)		 MGI
UniProt
GO_Central		 PMID:17702576 PMID:18287044 PMID:27777308 GO_REF:0000033 NCBI chr  X:154,541,238...154,565,046
Ensembl chr  X:154,541,199...154,565,046 		JBrowse link
G IL1A interleukin 1 alpha involved_in ISO
IEA		 RGD
Ensembl		 PMID:15671867 GO_REF:0000107 RGD:1358666 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta involved_in
acts_upstream_of		 ISO
IEA
IDA
IMP		 (PMID:26020802)
(PMID:18201371)		 RGD
Ensembl
ARUK-UCL
AgBase		 PMID:15671867 PMID:18201371 PMID:26020802 GO_REF:0000107 RGD:1358666 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G ILK integrin linked kinase involved_in IMP (PMID:21343177) CAFA PMID:21343177 NCBI chr11:6,603,774...6,610,870
Ensembl chr11:6,603,708...6,610,874 		JBrowse link
G INAVA innate immunity activator involved_in IMP (PMID:28436939) UniProt PMID:28436939 NCBI chr 1:200,891,531...200,915,742
Ensembl chr 1:200,891,048...200,915,742 		JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 involved_in
acts_upstream_of_or_within		 TAS
IMP
IBA		 (PMID:22158417) Reactome
MGI
GO_Central		 PMID:22158417 GO_REF:0000033 Reactome:R-HSA-937039 NCBI chr  X:154,010,507...154,019,902
Ensembl chr  X:154,010,506...154,019,902 		JBrowse link
G IRAK1BP1 interleukin 1 receptor associated kinase 1 binding protein 1 involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr 6:78,867,551...78,979,411
Ensembl chr 6:78,867,551...78,946,440 		JBrowse link
G IRAK2 interleukin 1 receptor associated kinase 2 NOT|acts_upstream_of_or_within ISO (PMID:12220507) MGI PMID:12220507 NCBI chr 3:10,164,919...10,243,745
Ensembl chr 3:10,164,919...10,243,745 		JBrowse link
G IRAK4 interleukin 1 receptor associated kinase 4 acts_upstream_of_or_within
involved_in		 IMP
IEA
IBA		 (PMID:22158417) MGI
UniProt
GO_Central		 PMID:22158417 GO_REF:0000033 GO_REF:0000117 NCBI chr12:43,758,951...43,789,541
Ensembl chr12:43,758,944...43,798,307 		JBrowse link
G IRF3 interferon regulatory factor 3 involved_in ISO
IEA		 RGD
Ensembl		 PMID:20670634 GO_REF:0000107 RGD:5128809 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875 		JBrowse link
G JMJD8 jumonji domain containing 8 involved_in IMP (PMID:27671354) UniProt PMID:27671354 NCBI chr16:681,670...684,334
Ensembl chr16:681,670...684,528 		JBrowse link
G LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 involved_in IDA (PMID:21343296) ARUK-UCL PMID:21343296 NCBI chr 1:110,401,253...110,407,924
Ensembl chr 1:110,401,249...110,407,942 		JBrowse link
G LGALS1 galectin 1 involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr22:37,675,636...37,679,802
Ensembl chr22:37,675,636...37,679,802 		JBrowse link
G LGALS9 galectin 9 involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr17:27,631,188...27,649,560
Ensembl chr17:27,629,798...27,649,560 		JBrowse link
G LIMS1 LIM zinc finger domain containing 1 involved_in IMP (PMID:21343177) CAFA PMID:21343177 NCBI chr 2:108,533,671...108,687,246
Ensembl chr 2:108,533,671...108,687,246 		JBrowse link
G LITAF lipopolysaccharide induced TNF factor involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr16:11,547,722...11,640,317
Ensembl chr16:11,547,722...11,636,381 		JBrowse link
G LPAR1 lysophosphatidic acid receptor 1 involved_in IEP (PMID:12761501) UniProt PMID:12761501 NCBI chr 9:110,873,263...111,038,998
Ensembl chr 9:110,873,263...111,038,470 		JBrowse link
G LRRC19 leucine rich repeat containing 19 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:26,993,136...27,005,672
Ensembl chr 9:26,993,136...27,005,672 		JBrowse link
G LTB lymphotoxin beta involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:31,580,558...31,582,425
Ensembl chr 6:31,580,525...31,582,522 		JBrowse link
G LTBR lymphotoxin beta receptor involved_in IEP
IEA
IBA		 (PMID:12761501) UniProt
InterPro
GO_Central		 PMID:12761501 GO_REF:0000002 GO_REF:0000033 NCBI chr12:6,375,160...6,391,566
Ensembl chr12:6,375,045...6,391,571 		JBrowse link
G LTF lactotransferrin involved_in IDA (PMID:20345905) UniProt PMID:20345905 NCBI chr 3:46,435,645...46,485,234
Ensembl chr 3:46,435,645...46,485,234 		JBrowse link
G LURAP1 leucine rich adaptor protein 1 involved_in IDA
IEA
IBA		 (PMID:21048106) UniProt
InterPro
GO_Central		 PMID:21048106 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:46,203,334...46,221,256
Ensembl chr 1:46,203,334...46,221,256 		JBrowse link
G LURAP1L leucine rich adaptor protein 1 like involved_in IEA InterPro GO_REF:0000002 NCBI chr 9:12,775,020...12,823,060
Ensembl chr 9:12,775,020...12,823,060 		JBrowse link
G MALT1 MALT1 paracaspase involved_in HMP
IEA
IDA		 (PMID:12761501)
(PMID:18223652)		 UniProt
TreeGrafter		 PMID:12761501 PMID:18223652 GO_REF:0000118 NCBI chr18:58,671,465...58,754,477
Ensembl chr18:58,671,465...58,754,477 		JBrowse link
G MAP3K3 mitogen-activated protein kinase kinase kinase 3 involved_in IEP (PMID:12761501) UniProt PMID:12761501 NCBI chr17:63,622,417...63,696,305
Ensembl chr17:63,622,415...63,696,305 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in ISO
IMP
IEA
IDA		 (PMID:14982987)
(PMID:11460167)		 RGD
UniProt
Ensembl
TreeGrafter		 PMID:11460167 PMID:14982987 PMID:17947700 GO_REF:0000107 GO_REF:0000118 RGD:5508194 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G MAS1 MAS1 proto-oncogene, G protein-coupled receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19404405) Ensembl
MGI		 PMID:19404405 GO_REF:0000107 NCBI chr 6:159,888,787...159,917,447
Ensembl chr 6:159,890,988...159,917,447 		JBrowse link
G MAVS mitochondrial antiviral signaling protein involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr20:3,846,834...3,876,118
Ensembl chr20:3,846,799...3,876,123 		JBrowse link
G MIB2 MIB E3 ubiquitin protein ligase 2 involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr 1:1,613,731...1,630,605
Ensembl chr 1:1,615,454...1,630,605 		JBrowse link
G MID2 midline 2 involved_in IDA (PMID:23077300) UniProt PMID:23077300 NCBI chr  X:107,825,735...107,931,637
Ensembl chr  X:107,825,755...107,931,637 		JBrowse link
G MIER1 MIER1 transcriptional regulator involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr 1:66,924,990...66,988,619
Ensembl chr 1:66,924,895...66,988,619 		JBrowse link
G MTDH metadherin involved_in IEA
IDA		 (PMID:16452207), (PMID:18316612) InterPro
UniProt		 PMID:16452207 PMID:18316612 GO_REF:0000002 NCBI chr 8:97,644,184...97,730,260
Ensembl chr 8:97,644,184...97,730,260 		JBrowse link
G MUL1 mitochondrial E3 ubiquitin protein ligase 1 involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr 1:20,499,448...20,508,151
Ensembl chr 1:20,499,448...20,508,151 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IEA
IEP		 (PMID:12761501) Ensembl
InterPro
UniProt		 PMID:12761501 GO_REF:0000002 GO_REF:0000107 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024 		JBrowse link
G NDFIP1 Nedd4 family interacting protein 1 involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr 5:142,108,779...142,154,440
Ensembl chr 5:142,108,779...142,154,440 		JBrowse link
G NDFIP2 Nedd4 family interacting protein 2 involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr13:79,481,155...79,556,077
Ensembl chr13:79,481,155...79,556,077 		JBrowse link
G NEK6 NIMA related kinase 6 involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr 9:124,257,606...124,353,307
Ensembl chr 9:124,257,606...124,353,307 		JBrowse link
G NFAT5 nuclear factor of activated T cells 5 involved_in IMP (PMID:25515214) ARUK-UCL PMID:25515214 NCBI chr16:69,565,966...69,704,654
Ensembl chr16:69,565,094...69,704,666 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 involved_in
acts_upstream_of_or_within		 IEA
IDA		 (PMID:10329646)
(PMID:12791997)		 Ensembl
MGI
UniProt		 PMID:10329646 PMID:12791997 GO_REF:0000107 NCBI chr 7:30,424,527...30,478,784
Ensembl chr 7:30,424,527...30,478,784 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within
involved_in		 IDA
IEA
IMP
IBA		 (PMID:12527755)
(PMID:15998797)
(PMID:11087742), (PMID:12514169), (PMID:12626759), (PMID:15044951), (PMID:17355968)		 MGI
Ensembl
UniProt
GO_Central		 PMID:11087742 PMID:12514169 PMID:12527755 PMID:12626759 PMID:15044951 More... GO_REF:0000033 GO_REF:0000107 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G NUP62 nucleoporin 62 involved_in IDA (PMID:10356400) UniProt PMID:10356400 NCBI chr19:49,906,825...49,929,504
Ensembl chr19:49,906,825...49,929,764 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in IDA (PMID:22464733) UniProt PMID:22464733 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PEDS1-UBE2V1 PEDS1-UBE2V1 readthrough involved_in IMP (PMID:16129784) HGNC-UCL PMID:16129784 NCBI chr20:50,081,124...50,153,723
Ensembl chr20:50,081,124...50,153,637 		JBrowse link
G PELI1 pellino E3 ubiquitin protein ligase 1 involved_in
acts_upstream_of_or_within		 IEA
TAS
ISO		 (PMID:19734906) Ensembl
Reactome
MGI		 PMID:19734906 GO_REF:0000107 Reactome:R-HSA-937039 NCBI chr 2:64,092,652...64,144,420
Ensembl chr 2:64,092,652...64,144,420 		JBrowse link
G PELI2 pellino E3 ubiquitin protein ligase family member 2 involved_in TAS Reactome Reactome:R-HSA-937039 NCBI chr14:56,118,411...56,301,524
Ensembl chr14:56,117,814...56,301,524 		JBrowse link
G PIM2 Pim-2 proto-oncogene, serine/threonine kinase involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:48,913,182...48,919,024
Ensembl chr  X:48,913,182...48,919,024 		JBrowse link
G PINK1 PTEN induced kinase 1 involved_in IDA (PMID:19880420) BHF-UCL PMID:19880420 NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511 		JBrowse link
G PLEKHG5 pleckstrin homology and RhoGEF domain containing G5 involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr 1:6,467,122...6,520,092
Ensembl chr 1:6,467,122...6,520,074 		JBrowse link
G PLK2 polo like kinase 2 involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr 5:58,453,982...58,460,086
Ensembl chr 5:58,453,982...58,460,139 		JBrowse link
G PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A involved_in HMP
IEA		 (PMID:12761501) UniProt
TreeGrafter		 PMID:12761501 GO_REF:0000118 NCBI chr14:60,245,750...60,299,087
Ensembl chr14:60,245,752...60,299,087 		JBrowse link
G PPM1B protein phosphatase, Mg2+/Mn2+ dependent 1B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 2:44,168,875...44,246,928
Ensembl chr 2:44,167,969...44,244,384 		JBrowse link
G PPP5C protein phosphatase 5 catalytic subunit involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr19:46,347,087...46,390,975
Ensembl chr19:46,347,087...46,392,981 		JBrowse link
G PRKCB protein kinase C beta involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr16:23,835,983...24,220,611
Ensembl chr16:23,835,983...24,220,611 		JBrowse link
G PRKCE protein kinase C epsilon involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11696589) Ensembl
MGI		 PMID:11696589 GO_REF:0000107 NCBI chr 2:45,651,279...46,187,990
Ensembl chr 2:45,651,345...46,187,990 		JBrowse link
G PRKD1 protein kinase D1 involved_in IMP (PMID:12505989) UniProt PMID:12505989 NCBI chr14:29,576,479...29,927,847
Ensembl chr14:29,576,479...30,191,898 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IMP
IDA		 (PMID:23453807)
(PMID:17314283), (PMID:19880420)		 ParkinsonsUK-UCL PMID:17314283 PMID:19880420 PMID:23453807 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
G PRL prolactin involved_in IDA (PMID:23619365) BHF-UCL PMID:23619365 NCBI chr 6:22,287,246...22,302,835
Ensembl chr 6:22,287,244...22,302,826 		JBrowse link
G PYCARD PYD and CARD domain containing involved_in IDA (PMID:12656673) HGNC-UCL PMID:12656673 NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450 		JBrowse link
G RBCK1 RANBP2-type and C3HC4-type zinc finger containing 1 involved_in IEA
IDA
IBA		 (PMID:19136968), (PMID:21455173) Ensembl
UniProt
GO_Central		 PMID:19136968 PMID:21455173 GO_REF:0000033 GO_REF:0000107 NCBI chr20:408,299...432,139
Ensembl chr20:407,498...432,139 		JBrowse link
G RBX1 ring-box 1 involved_in IDA (PMID:10644755) UniProt PMID:10644755 NCBI chr22:40,951,378...40,973,309
Ensembl chr22:40,951,347...40,973,309 		JBrowse link
G REL REL proto-oncogene, NF-kB subunit involved_in IEP (PMID:12761501) UniProt PMID:12761501 NCBI chr 2:60,881,574...60,931,612
Ensembl chr 2:60,881,491...60,931,612 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in IEP
IEA		 (PMID:12761501) UniProt
Ensembl		 PMID:12761501 GO_REF:0000107 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RFPL1 ret finger protein like 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr22:29,387,909...29,442,455
Ensembl chr22:29,438,583...29,442,455 		JBrowse link
G RFPL2 ret finger protein like 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr22:32,190,438...32,205,073
Ensembl chr22:32,190,435...32,205,073 		JBrowse link
G RFPL3 ret finger protein like 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr22:32,354,885...32,361,161
Ensembl chr22:32,354,885...32,361,161 		JBrowse link
G RFPL4A ret finger protein like 4A involved_in IBA GO_Central GO_REF:0000033 NCBI chr19:55,757,294...55,763,421
Ensembl chr19:55,759,097...55,763,421 		JBrowse link
G RFPL4AL1 ret finger protein like 4A like 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr19:55,769,118...55,773,420
Ensembl chr19:55,769,118...55,773,420 		JBrowse link
G RHOA ras homolog family member A involved_in IEP
IMP		 (PMID:12761501)
(PMID:25515214)		 UniProt
ARUK-UCL		 PMID:12761501 PMID:25515214 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998 		JBrowse link
G RHOC ras homolog family member C involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr 1:112,701,131...112,707,408
Ensembl chr 1:112,701,127...112,707,434 		JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 involved_in
acts_upstream_of_or_within		 IEA
IEP
IDA
ISO		 (PMID:12761501)
(PMID:17389591)
(PMID:22089168)		 Ensembl
UniProt
MGI		 PMID:12761501 PMID:17389591 PMID:22089168 GO_REF:0000107 GO_REF:0000117 NCBI chr 6:3,063,967...3,115,187
Ensembl chr 6:3,063,824...3,115,187 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 IEA
IDA
IBA		 (PMID:10329646) Ensembl
MGI
UniProt
GO_Central		 PMID:10329646 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064 		JBrowse link
G RNF31 ring finger protein 31 involved_in IEA
IDA		 (PMID:19136968), (PMID:21455173), (PMID:23806334), (PMID:28481331) Ensembl
UniProt		 PMID:19136968 PMID:21455173 PMID:23806334 PMID:28481331 GO_REF:0000107 NCBI chr14:24,146,875...24,160,655
Ensembl chr14:24,146,683...24,160,660 		JBrowse link
G ROR1 receptor tyrosine kinase like orphan receptor 1 involved_in IMP
IEA
IBA		 (PMID:27162350) UniProt
TreeGrafter
GO_Central		 PMID:27162350 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:63,774,017...64,181,498
Ensembl chr 1:63,774,017...64,181,498 		JBrowse link
G S100A1 S100 calcium binding protein A1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:153,628,434...153,632,039
Ensembl chr 1:153,627,926...153,632,039 		JBrowse link
G S100A12 S100 calcium binding protein A12 involved_in IDA
IBA		 (PMID:15033494) UniProt
GO_Central		 PMID:15033494 GO_REF:0000033 NCBI chr 1:153,373,711...153,375,621
Ensembl chr 1:153,373,711...153,375,621 		JBrowse link
G S100A13 S100 calcium binding protein A13 involved_in IDA
IBA		 (PMID:15033494) UniProt
GO_Central		 PMID:15033494 GO_REF:0000033 NCBI chr 1:153,618,799...153,634,361
Ensembl chr 1:153,618,787...153,631,360 		JBrowse link
G S100A4 S100 calcium binding protein A4 involved_in IDA
IBA
IEA		 (PMID:15033494) UniProt
GO_Central
TreeGrafter		 PMID:15033494 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:153,543,621...153,545,806
Ensembl chr 1:153,543,613...153,550,136 		JBrowse link
G S100B S100 calcium binding protein B involved_in IDA
IEA
IBA		 (PMID:15033494) UniProt
TreeGrafter
GO_Central		 PMID:15033494 GO_REF:0000033 GO_REF:0000118 NCBI chr21:46,598,604...46,605,082
Ensembl chr21:46,598,604...46,605,208 		JBrowse link
G SECTM1 secreted and transmembrane 1 involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr17:82,321,024...82,333,959
Ensembl chr17:82,321,024...82,334,074 		JBrowse link
G SHARPIN SHANK associated RH domain interactor involved_in IDA
IEA
IBA		 (PMID:21455173) UniProt
Ensembl
TreeGrafter
GO_Central		 PMID:21455173 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:144,098,637...144,103,773
Ensembl chr 8:144,098,633...144,108,124 		JBrowse link
G SHISA5 shisa family member 5 involved_in HMP
IEA		 (PMID:12761501) UniProt
TreeGrafter		 PMID:12761501 GO_REF:0000118 NCBI chr 3:48,467,876...48,504,810
Ensembl chr 3:48,467,798...48,504,826 		JBrowse link
G SLC20A1 solute carrier family 20 member 1 involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr 2:112,645,939...112,663,825
Ensembl chr 2:112,645,939...112,663,825 		JBrowse link
G SLC35B2 solute carrier family 35 member B2 involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr 6:44,254,101...44,257,890
Ensembl chr 6:44,254,096...44,257,890 		JBrowse link
G SLC44A2 solute carrier family 44 member 2 (CTL2 blood group) involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr19:10,602,455...10,644,557
Ensembl chr19:10,602,457...10,644,557 		JBrowse link
G TAB2 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 involved_in IEP
IDA
IEA
IBA		 (PMID:12761501)
(PMID:15327770), (PMID:18079694), (PMID:22158122)		 UniProt
TreeGrafter
GO_Central		 PMID:12761501 PMID:15327770 PMID:18079694 PMID:22158122 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:149,217,926...149,411,607
Ensembl chr 6:149,218,641...149,411,613 		JBrowse link
G TAB3 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 involved_in IMP
IDA
IEA
IBA		 (PMID:23487264)
(PMID:15327770), (PMID:18079694), (PMID:22158122)		 ARUK-UCL
UniProt
TreeGrafter
GO_Central		 PMID:15327770 PMID:18079694 PMID:22158122 PMID:23487264 GO_REF:0000033 GO_REF:0000118 NCBI chr  X:30,827,442...30,889,254
Ensembl chr  X:30,827,442...30,975,084 		JBrowse link
G TBK1 TANK binding kinase 1 involved_in IEP (PMID:12761501) UniProt PMID:12761501 NCBI chr12:64,452,120...64,502,114
Ensembl chr12:64,452,090...64,502,114 		JBrowse link
G TERF2IP TERF2 interacting protein involved_in ISO (MGI:4821187|PMID:20622870) UniProt PMID:20622870 MGI:4821187 NCBI chr16:75,760,050...75,914,672
Ensembl chr16:75,647,773...75,761,872 		JBrowse link
G TERF2IP TERF2 interacting protein involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr16:75,647,773...75,657,432
Ensembl chr16:75,647,773...75,761,872 		JBrowse link
G TFG trafficking from ER to golgi regulator involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr 3:100,709,290...100,748,967
Ensembl chr 3:100,709,295...100,748,964 		JBrowse link
G TFRC transferrin receptor involved_in IMP (PMID:23016877) ARUK-UCL PMID:23016877 NCBI chr 3:196,049,284...196,082,090
Ensembl chr 3:196,012,511...196,082,153 		JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in IMP (PMID:25196641) BHF-UCL PMID:25196641 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TGM2 transglutaminase 2 ISO RGD PMID:15471861 RGD:1579987 NCBI chr20:38,127,385...38,168,475
Ensembl chr20:38,127,385...38,166,578 		JBrowse link
G TICAM1 TIR domain containing adaptor molecule 1 involved_in ISS
IEA
IMP
HMP
IBA		 (PMID:14982987)
(PMID:12761501)		 UniProt
Ensembl
GO_Central		 PMID:12761501 PMID:14982987 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr19:4,815,932...4,831,712
Ensembl chr19:4,815,932...4,831,712 		JBrowse link
G TICAM2 TIR domain containing adaptor molecule 2 involved_in HMP
IBA		 (PMID:12761501) UniProt
GO_Central		 PMID:12761501 GO_REF:0000033 NCBI chr 5:115,578,496...115,602,479
Ensembl chr 5:115,578,496...115,602,479 		JBrowse link
G TIFA TRAF interacting protein with forkhead associated domain involved_in IDA
IEA
IBA		 (PMID:26068852), (PMID:28222186), (PMID:28877472), (PMID:30111836) UniProt
Ensembl
GO_Central
TreeGrafter
InterPro		 PMID:26068852 PMID:28222186 PMID:28877472 PMID:30111836 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:112,274,537...112,285,904
Ensembl chr 4:112,272,968...112,285,955 		JBrowse link
G TIFAB TIFA inhibitor involved_in IEA InterPro GO_REF:0000002 NCBI chr 5:135,444,226...135,452,351
Ensembl chr 5:135,444,226...135,452,351 		JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in IMP
IBA		 (PMID:19509286), (PMID:24275656) AgBase
GO_Central		 PMID:19509286 PMID:24275656 GO_REF:0000033 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845 		JBrowse link
G TLR3 toll like receptor 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19734906) Ensembl
MGI		 PMID:19734906 GO_REF:0000107 NCBI chr 4:186,069,156...186,088,073
Ensembl chr 4:186,068,911...186,088,073 		JBrowse link
G TLR4 toll like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
IGI
ISO		 (PMID:20037584)
(PMID:19734906)		 Ensembl
ARUK-UCL
MGI		 PMID:19734906 PMID:20037584 GO_REF:0000107 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TLR6 toll like receptor 6 acts_upstream_of_or_within
involved_in		 IDA
IGI		 (PMID:10231569)
(PMID:20037584)		 MGI
ARUK-UCL		 PMID:10231569 PMID:20037584 NCBI chr 4:38,822,897...38,868,390
Ensembl chr 4:38,822,897...38,856,817 		JBrowse link
G TLR7 toll like receptor 7 involved_in IDA (PMID:12032557) GO_Central PMID:12032557 NCBI chr  X:12,867,072...12,890,361
Ensembl chr  X:12,867,072...12,890,361 		JBrowse link
G TLR8 toll like receptor 8 involved_in IDA (PMID:12032557) UniProt PMID:12032557 NCBI chr  X:12,906,620...12,923,169
Ensembl chr  X:12,906,620...12,923,169 		JBrowse link
G TLR9 toll like receptor 9 involved_in IDA (PMID:17128265), (PMID:19740627) BHF-UCL PMID:17128265 PMID:19740627 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
G TMED4 transmembrane p24 trafficking protein 4 involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr 7:44,577,894...44,582,231
Ensembl chr 7:44,577,894...44,582,287 		JBrowse link
G TMED7-TICAM2 TMED7-TICAM2 readthrough involved_in HMP
IBA		 (PMID:12761501) UniProt
GO_Central		 PMID:12761501 GO_REF:0000033 NCBI chr 5:115,578,496...115,626,036
Ensembl chr 5:115,578,642...115,626,161 		JBrowse link
G TMEM101 transmembrane protein 101 involved_in HMP
IEA		 (PMID:12761501) UniProt
TreeGrafter		 PMID:12761501 GO_REF:0000118 NCBI chr17:44,011,188...44,023,215
Ensembl chr17:44,011,188...44,023,946 		JBrowse link
G TMEM106A transmembrane protein 106A involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:43,211,875...43,220,041
Ensembl chr17:43,211,835...43,220,041 		JBrowse link
G TMEM9B TMEM9 domain family member B involved_in HMP
IEA		 (PMID:12761501) UniProt
TreeGrafter		 PMID:12761501 GO_REF:0000118 NCBI chr11:8,947,202...8,964,947
Ensembl chr11:8,947,202...8,965,011 		JBrowse link
G TNF tumor necrosis factor involved_in ISO
TAS
IEA
ISS
IDA
IMP
NAS
IBA		 (PMID:29702085)
(PMID:11374864), (PMID:15310755), (PMID:17922812)
(PMID:18201371)
(PMID:23878390)		 RGD
ARUK-UCL
Ensembl
AgBase
BHF-UCL
GO_Central		 PMID:11374864 PMID:12631113 PMID:15310755 PMID:17922812 PMID:18201371 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 RGD:1580306 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF10B TNF receptor superfamily member 10b involved_in IEP (PMID:12761501) UniProt PMID:12761501 NCBI chr 8:23,020,133...23,069,031
Ensembl chr 8:23,020,133...23,069,031 		JBrowse link
G TNFRSF19 TNF receptor superfamily member 19 involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 (PMID:10764796) Ensembl
InterPro
GO_Central
MGI		 PMID:10764796 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr13:23,570,412...23,676,093
Ensembl chr13:23,570,370...23,676,104 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A involved_in IEP
IEA		 (PMID:12761501) UniProt
Ensembl		 PMID:12761501 GO_REF:0000107 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TNFSF10 TNF superfamily member 10 involved_in IEP
IBA		 (PMID:12761501) UniProt
GO_Central		 PMID:12761501 GO_REF:0000033 NCBI chr 3:172,505,508...172,523,430
Ensembl chr 3:172,505,508...172,523,475 		JBrowse link
G TNFSF11 TNF superfamily member 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:42,562,736...42,608,013
Ensembl chr13:42,562,736...42,608,013 		JBrowse link
G TNIP2 TNFAIP3 interacting protein 2 involved_in IDA
IBA		 (PMID:21784860) UniProt
GO_Central		 PMID:21784860 GO_REF:0000033 NCBI chr 4:2,741,648...2,756,336
Ensembl chr 4:2,741,648...2,756,342 		JBrowse link
G TRADD TNFRSF1A associated via death domain involved_in IEP
IEA		 (PMID:12761501) UniProt
InterPro
Ensembl		 PMID:12761501 GO_REF:0000002 GO_REF:0000107 NCBI chr16:67,154,185...67,159,909
Ensembl chr16:67,154,185...67,159,909 		JBrowse link
G TRAF2 TNF receptor associated factor 2 involved_in IEA
IBA		 Ensembl
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:136,881,958...136,926,607
Ensembl chr 9:136,881,912...136,926,607 		JBrowse link
G TRAF3IP2 TRAF3 interacting protein 2 involved_in IEP
IBA		 (PMID:12761501) UniProt
GO_Central		 PMID:12761501 GO_REF:0000033 NCBI chr 6:111,555,381...111,605,878
Ensembl chr 6:111,555,381...111,606,906 		JBrowse link
G TRAF5 TNF receptor associated factor 5 involved_in IEP
IEA		 (PMID:12761501) UniProt
InterPro		 PMID:12761501 GO_REF:0000002 NCBI chr 1:211,326,635...211,374,946
Ensembl chr 1:211,326,615...211,374,946 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in IDA
IEA		 (PMID:17135271) UniProt
Ensembl		 PMID:17135271 GO_REF:0000107 NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272 		JBrowse link
G TRIM13 tripartite motif containing 13 involved_in HMP
IDA
IBA
IEA		 (PMID:12761501)
(PMID:23077300)		 UniProt
GO_Central
TreeGrafter		 PMID:12761501 PMID:23077300 GO_REF:0000033 GO_REF:0000118 NCBI chr13:49,997,042...50,018,467
Ensembl chr13:49,995,888...50,020,481 		JBrowse link
G TRIM21 tripartite motif containing 21 involved_in IBA GO_Central GO_REF:0000033 NCBI chr11:4,384,897...4,393,702
Ensembl chr11:4,384,897...4,393,702 		JBrowse link
G TRIM22 tripartite motif containing 22 involved_in IDA
IEA
IBA		 (PMID:23077300) UniProt
TreeGrafter
GO_Central		 PMID:23077300 GO_REF:0000033 GO_REF:0000118 NCBI chr11:5,689,790...5,710,863
Ensembl chr11:5,689,610...5,737,089 		JBrowse link
G TRIM25 tripartite motif containing 25 involved_in IDA (PMID:23077300) UniProt PMID:23077300 NCBI chr17:56,887,909...56,914,049
Ensembl chr17:56,836,387...56,914,080 		JBrowse link
G TRIM32 tripartite motif containing 32 involved_in IDA (PMID:23077300) UniProt PMID:23077300 NCBI chr 9:116,687,305...116,701,299
Ensembl chr 9:116,687,305...116,701,300 		JBrowse link
G TRIM34 tripartite motif containing 34 involved_in IBA GO_Central GO_REF:0000033 NCBI chr11:5,619,944...5,644,398
Ensembl chr11:5,619,764...5,644,398 		JBrowse link
G TRIM38 tripartite motif containing 38 involved_in HMP
IDA
IBA		 (PMID:12761501)
(PMID:23077300)		 UniProt
GO_Central		 PMID:12761501 PMID:23077300 GO_REF:0000033 NCBI chr 6:25,962,802...25,991,231
Ensembl chr 6:25,962,802...25,991,231 		JBrowse link
G TRIM5 tripartite motif containing 5 involved_in IDA
IMP
IBA
IEA		 (PMID:23077300)
(PMID:21512573)		 UniProt
GO_Central
TreeGrafter		 PMID:21512573 PMID:23077300 GO_REF:0000033 GO_REF:0000118 NCBI chr11:5,588,635...5,685,074
Ensembl chr11:5,663,195...5,938,619 		JBrowse link
G TRIM52 tripartite motif containing 52 involved_in IDA (PMID:27667714), (PMID:28073078) UniProt PMID:27667714 PMID:28073078 NCBI chr 5:181,249,062...181,261,143
Ensembl chr 5:181,254,077...181,261,150 		JBrowse link
G TRIM58 tripartite motif containing 58 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:247,857,187...247,880,138
Ensembl chr 1:247,857,187...247,880,138 		JBrowse link
G TRIM6 tripartite motif containing 6 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr11:5,596,111...5,612,952
Ensembl chr11:5,596,109...5,612,958 		JBrowse link
G TRIM62 tripartite motif containing 62 involved_in IDA
IBA		 (PMID:23077300) UniProt
GO_Central		 PMID:23077300 GO_REF:0000033 NCBI chr 1:33,145,399...33,182,043
Ensembl chr 1:33,145,399...33,182,059 		JBrowse link
G TRIM68 tripartite motif containing 68 involved_in IBA GO_Central GO_REF:0000033 NCBI chr11:4,598,672...4,608,231
Ensembl chr11:4,598,672...4,608,231 		JBrowse link
G TRIM8 tripartite motif containing 8 involved_in IDA (PMID:23077300) UniProt PMID:23077300 NCBI chr10:102,644,479...102,658,319
Ensembl chr10:102,642,503...102,658,318 		JBrowse link
G TSPAN6 tetraspanin 6 involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr  X:100,627,108...100,637,104
Ensembl chr  X:100,627,108...100,639,991 		JBrowse link
G UBD ubiquitin D involved_in IMP
IEA
IBA		 (PMID:19959714) UniProt
Ensembl
GO_Central
TreeGrafter		 PMID:19959714 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:29,555,515...29,559,732
Ensembl chr 6:29,555,515...29,559,732 		JBrowse link
G UBE2I ubiquitin conjugating enzyme E2 I acts_upstream_of_or_within ISO (PMID:9223278) MGI PMID:9223278 NCBI chr16:1,309,152...1,327,017
Ensembl chr16:1,291,444...1,327,018 		JBrowse link
G UBE2N ubiquitin conjugating enzyme E2 N involved_in IMP (PMID:16129784) HGNC-UCL PMID:16129784 NCBI chr12:93,405,684...93,441,947
Ensembl chr12:93,405,673...93,441,947 		JBrowse link
G UBE2V1 ubiquitin conjugating enzyme E2 V1 involved_in IMP (PMID:16129784) HGNC-UCL PMID:16129784 NCBI chr20:50,081,124...50,115,957
Ensembl chr20:50,081,124...50,115,959 		JBrowse link
G UNC5CL unc-5 family C-terminal like acts_upstream_of_or_within
involved_in		 IDA
IBA
IEA		 (PMID:22158417) MGI
GO_Central
TreeGrafter		 PMID:22158417 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:41,026,895...41,039,221
Ensembl chr 6:41,026,895...41,039,221 		JBrowse link
G VAPA VAMP associated protein A involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr18:9,914,016...9,960,021
Ensembl chr18:9,914,016...9,960,021 		JBrowse link
G VEGFA vascular endothelial growth factor A involved_in NAS (PMID:23878390) BHF-UCL PMID:23878390 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G WLS Wnt ligand secretion mediator involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:68,098,459...68,232,546
Ensembl chr 1:68,098,473...68,233,120 		JBrowse link
G XIAP X-linked inhibitor of apoptosis involved_in IDA (PMID:19667203), (PMID:22607974) UniProt PMID:19667203 PMID:22607974 NCBI chr  X:123,859,708...123,913,972
Ensembl chr  X:123,859,712...123,913,972 		JBrowse link
G ZC3HAV1 zinc finger CCCH-type containing, antiviral 1 involved_in IMP (PMID:21102435) UniProt PMID:21102435 NCBI chr 7:139,043,515...139,109,720
Ensembl chr 7:139,043,515...139,132,122 		JBrowse link
G ZDHHC13 zinc finger DHHC-type palmitoyltransferase 13 involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr11:19,117,104...19,176,415
Ensembl chr11:19,117,099...19,176,422 		JBrowse link
G ZDHHC17 zinc finger DHHC-type palmitoyltransferase 17 involved_in HMP (PMID:12761501) UniProt PMID:12761501 NCBI chr12:76,764,115...76,853,701
Ensembl chr12:76,764,103...76,853,696 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19613
    positive regulation of biological process 7043
      positive regulation of signaling 2141
        positive regulation of signal transduction 1793
          positive regulation of intracellular signal transduction 1181
            positive regulation of canonical NF-kappaB signal transduction 226
Path 2
Term Annotations click to browse term
  biological_process 19613
    biological regulation 13363
      regulation of biological process 12979
        signaling 7170
          signal transduction 6566
            intracellular signal transduction 2993
              intracellular signaling cassette 2123
                canonical NF-kappaB signal transduction 336
                  regulation of canonical NF-kappaB signal transduction 314
                    positive regulation of canonical NF-kappaB signal transduction 226
paths to the root