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ONTOLOGY REPORT - ANNOTATIONS

Term:epithelial to mesenchymal transition
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Accession:GO:0001837 term browser browse the term
Definition:A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
Synonyms:exact_synonym: EMT;   epithelial-mesenchymal transition;   mesenchymal cell differentiation from epithelial cell


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epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akna AT-hook transcription factor involved_in IDA
IBA		 (MGI:6294240|PMID:30787442) UniProt
GO_Central		 PMID:30787442 GO_REF:0000033 MGI:6294240 NCBI chr 4:63,285,364...63,328,988
Ensembl chr 4:63,285,362...63,321,591 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within		 IMP
ISO		 (MGI:3640731|PMID:16730346), (MGI:5299248|PMID:21983003)
(PMID:15110716)		 BHF-UCL
MGI		 PMID:15110716 PMID:16730346 PMID:21983003 GO_REF:0000119 MGI:3640731 MGI:4834177 MGI:5299248 NCBI chr 2:133,394,079...133,404,816
Ensembl chr 2:133,394,079...133,404,805 		JBrowse link
G Cul7 cullin 7 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr17:46,961,264...46,975,290
Ensembl chr17:46,961,263...46,975,290 		JBrowse link
G Dact3 dishevelled-binding antagonist of beta-catenin 3 acts_upstream_of IMP (PMID:23580654) MGI PMID:23580654 NCBI chr 7:16,609,242...16,621,226
Ensembl chr 7:16,609,242...16,621,387 		JBrowse link
G Ddx17 DEAD box helicase 17 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr15:79,411,897...79,430,976
Ensembl chr15:79,411,937...79,430,942 		JBrowse link
G Ddx5 DEAD box helicase 5 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:106,671,181...106,680,011
Ensembl chr11:106,671,181...106,680,011 		JBrowse link
G Dlg5 discs large MAGUK scaffold protein 5 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr14:24,184,021...24,295,988
Ensembl chr14:24,184,021...24,295,988 		JBrowse link
G Eng endoglin involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:32,536,607...32,572,681
Ensembl chr 2:32,536,607...32,572,681 		JBrowse link
G Epb41l5 erythrocyte membrane protein band 4.1 like 5 involved_in IMP (PMID:17507402)
(PMID:18794329)		 MGI PMID:17507402 PMID:18794329 NCBI chr 1:119,472,762...119,576,826
Ensembl chr 1:119,472,767...119,576,730 		JBrowse link
G Fam83d family with sequence similarity 83, member D involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:158,610,011...158,628,557
Ensembl chr 2:158,610,013...158,628,557 		JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 8:26,008,808...26,067,819
Ensembl chr 8:26,003,670...26,065,734 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 involved_in ISO RGD
MGI		 PMID:7803853 GO_REF:0000096 MGI:4417868 RGD:632663 NCBI chr 7:129,764,181...129,868,538
Ensembl chr 7:129,764,181...132,725,079 		JBrowse link
G Flna filamin, alpha acts_upstream_of_or_within IGI (PMID:21709252) MGI PMID:21709252 NCBI chr  X:73,267,067...73,293,787
Ensembl chr  X:73,267,067...73,293,426 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446 		JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit involved_in IMP (MGI:3772289|PMID:18037992) BHF-UCL PMID:18037992 MGI:3772289 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304 		JBrowse link
G Hmga2 high mobility group AT-hook 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:120,197,173...120,312,374
Ensembl chr10:120,197,180...120,312,374 		JBrowse link
G Hnrnpab heterogeneous nuclear ribonucleoprotein A/B involved_in IDA (MGI:3698386|PMID:17273560) HGNC-UCL PMID:17273560 MGI:3698386 NCBI chr11:51,490,927...51,497,708
Ensembl chr11:51,490,927...51,497,674 		JBrowse link
G Lef1 lymphoid enhancer binding factor 1 involved_in IMP (MGI:2683382|PMID:14691138) BHF-UCL PMID:14691138 MGI:2683382 NCBI chr 3:130,903,972...131,018,006
Ensembl chr 3:130,904,120...131,018,005 		JBrowse link
G Lims1 LIM and senescent cell antigen-like domains 1 NOT|involved_in ISO (PMID:20926685) UniProt PMID:20926685 NCBI chr10:58,159,164...58,260,513
Ensembl chr10:58,159,288...58,260,513 		JBrowse link
G Loxl2 lysyl oxidase-like 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr14:69,846,085...69,933,283
Ensembl chr14:69,846,517...69,933,283 		JBrowse link
G Loxl3 lysyl oxidase-like 3 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 6:83,011,186...83,029,547
Ensembl chr 6:83,011,154...83,029,543 		JBrowse link
G Mir326 microRNA 326 involved_in ISO (PMID:24279830) BHF-UCL PMID:24279830 NCBI chr 7:99,201,476...99,201,570
Ensembl chr 7:99,201,476...99,201,570 		JBrowse link
G Msx1 msh homeobox 1 involved_in IMP (MGI:4418636|PMID:11023873) UniProt PMID:11023873 MGI:4418636 NCBI chr 5:37,977,835...37,981,929
Ensembl chr 5:37,977,829...37,981,927 		JBrowse link
G Ncam1 neural cell adhesion molecule 1 involved_in IDA (MGI:6781126|PMID:28098160) UniProt PMID:28098160 MGI:6781126 NCBI chr 9:49,413,434...49,710,909
Ensembl chr 9:49,413,436...49,710,225 		JBrowse link
G Nfatc1 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 acts_upstream_of_or_within IMP (PMID:15339668) MGI PMID:15339668 NCBI chr18:80,649,418...80,756,286
Ensembl chr18:80,649,420...80,756,286 		JBrowse link
G Nog noggin involved_in IMP (MGI:3783944|PMID:17218603) BHF-UCL PMID:17218603 MGI:3783944 NCBI chr11:89,191,464...89,193,385
Ensembl chr11:89,191,464...89,193,158 		JBrowse link
G Notch1 notch 1 involved_in
acts_upstream_of_or_within		 ISO
IMP		 (PMID:14701881) MGI PMID:14701881 GO_REF:0000119 MGI:4834177 NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675 		JBrowse link
G Notch4 notch 4 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr17:34,783,257...34,807,517
Ensembl chr17:34,783,242...34,807,477 		JBrowse link
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) acts_upstream_of_or_within IMP (PMID:15339668) MGI PMID:15339668 NCBI chr11:17,109,298...17,150,380
Ensembl chr11:17,109,263...17,150,375 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region acts_upstream_of_or_within IMP (PMID:14701881) MGI PMID:14701881 NCBI chr 5:53,713,121...53,814,787
Ensembl chr 5:53,623,494...53,814,704 		JBrowse link
G Rflnb refilin B acts_upstream_of_or_within IGI (PMID:21709252) MGI PMID:21709252 NCBI chr11:75,910,020...75,918,608
Ensembl chr11:75,910,020...75,918,608 		JBrowse link
G Rian RNA imprinted and accumulated in nucleus acts_upstream_of_or_within IMP (PMID:29636669), (PMID:31711641) MGI PMID:29636669 PMID:31711641 NCBI chr12:109,570,379...109,628,150
Ensembl chr12:109,570,242...109,628,150 		JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in IGI (MGI:3513217|PMID:15464581) BHF-UCL PMID:15464581 MGI:3513217 NCBI chr18:10,064,401...10,182,225
Ensembl chr18:10,064,401...10,182,045 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in IGI (MGI:3513217|PMID:15464581) BHF-UCL PMID:15464581 MGI:3513217 NCBI chr12:16,944,808...17,038,275
Ensembl chr12:16,944,896...17,037,824 		JBrowse link
G Sdhaf2 succinate dehydrogenase complex assembly factor 2 acts_upstream_of IMP (PMID:23983127) MGI PMID:23983127 NCBI chr19:10,477,876...10,502,573
Ensembl chr19:10,477,898...10,503,506 		JBrowse link
G Slc39a10 solute carrier family 39 (zinc transporter), member 10 involved_in IDA
ISO		 (MGI:6781126|PMID:28098160) UniProt
MGI		 PMID:28098160 GO_REF:0000119 MGI:4834177 MGI:6781126 NCBI chr 1:46,846,704...46,964,952
Ensembl chr 1:46,846,704...46,932,012 		JBrowse link
G Slc39a6 solute carrier family 39 (metal ion transporter), member 6 involved_in IDA
ISO		 (MGI:6781126|PMID:28098160) UniProt
MGI		 PMID:28098160 GO_REF:0000119 MGI:4834177 MGI:6781126 NCBI chr18:24,712,938...24,736,874
Ensembl chr18:24,712,938...24,736,874 		JBrowse link
G Smad4 SMAD family member 4 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr18:73,767,861...73,836,862
Ensembl chr18:73,772,080...73,836,851 		JBrowse link
G Snai1 snail family zinc finger 1 involved_in IDA
ISO
IMP		 (MGI:1352954|PMID:10655586)
(MGI:2153695|PMID:11689706), (MGI:5294539|PMID:18832382)		 UniProt
MGI		 PMID:10655586 PMID:11689706 PMID:18832382 GO_REF:0000119 MGI:1352954 MGI:2153695 MGI:4834177 MGI:5294539 NCBI chr 2:167,380,115...167,384,734
Ensembl chr 2:167,380,115...167,384,734 		JBrowse link
G Snai2 snail family zinc finger 2 involved_in
acts_upstream_of_or_within		 IMP
ISO		 (MGI:892810|PMID:9182671)
(PMID:17916597)		 BHF-UCL
MGI		 PMID:9182671 PMID:17916597 GO_REF:0000119 MGI:4834177 MGI:892810 NCBI chr16:14,523,716...14,527,259
Ensembl chr16:14,523,716...14,527,249 		JBrowse link
G Sox9 SRY (sex determining region Y)-box 9 acts_upstream_of_or_within IMP (PMID:15096597) MGI PMID:15096597 NCBI chr11:112,673,036...112,678,583
Ensembl chr11:112,673,050...112,678,586 		JBrowse link
G Sp6 trans-acting transcription factor 6 involved_in IMP (MGI:6305509|PMID:30504223) UniProt PMID:30504223 MGI:6305509 NCBI chr11:96,904,395...96,915,565
Ensembl chr11:96,904,220...96,915,560 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of_or_within
involved_in		 ISO (PMID:29529050) RGD
MGI		 PMID:10504497 PMID:29529050 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:1578678 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:186,354,984...186,441,504
Ensembl chr 1:186,354,989...186,438,186 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor I involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:47,353,258...47,414,926
Ensembl chr 4:47,353,222...47,414,931 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor II involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:115,916,763...116,004,431
Ensembl chr 9:115,913,361...116,004,428 		JBrowse link
G Tgfbr3 transforming growth factor, beta receptor III involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 5:107,254,433...107,437,495
Ensembl chr 5:107,254,436...107,437,495 		JBrowse link
G Tgfbr3l transforming growth factor, beta receptor III-like involved_in IBA GO_Central GO_REF:0000033 NCBI chr 8:4,297,994...4,301,528
Ensembl chr 8:4,298,214...4,301,423 		JBrowse link
G Trim28 tripartite motif-containing 28 involved_in IDA (MGI:3698386|PMID:17273560) HGNC-UCL PMID:17273560 MGI:3698386 NCBI chr 7:12,758,079...12,764,959
Ensembl chr 7:12,733,041...12,764,962 		JBrowse link
G Trip10 thyroid hormone receptor interactor 10 involved_in ISO RGD
MGI		 PMID:23819628 GO_REF:0000096 MGI:4417868 RGD:11535143 NCBI chr17:57,540,227...57,570,712
Ensembl chr17:57,556,455...57,570,665 		JBrowse link
G Wnt11 wingless-type MMTV integration site family, member 11 acts_upstream_of_or_within IGI (PMID:25813538) MGI PMID:25813538 NCBI chr 7:98,484,293...98,503,954
Ensembl chr 7:98,484,319...98,504,402 		JBrowse link
G Wnt4 wingless-type MMTV integration site family, member 4 involved_in ISO (PMID:12841867) UniProt PMID:12841867 NCBI chr 4:137,004,946...137,026,812
Ensembl chr 4:137,004,800...137,027,037 		JBrowse link
G Wnt5a wingless-type MMTV integration site family, member 5A involved_in ISO (PMID:12841867) UniProt PMID:12841867 NCBI chr14:28,224,962...28,249,405
Ensembl chr14:28,226,707...28,249,405 		JBrowse link
cardiac epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam15 ADAM metallopeptidase domain 15 acts_upstream_of_or_within IMP (PMID:19156209) MGI PMID:19156209 NCBI chr 3:89,246,947...89,257,589
Ensembl chr 3:89,245,849...89,257,303 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:133,394,079...133,404,816
Ensembl chr 2:133,394,079...133,404,805 		JBrowse link
G Hey1 hairy/enhancer-of-split related with YRPW motif 1 involved_in IGI (MGI:3783952|PMID:17303760) BHF-UCL PMID:17303760 MGI:3783952 NCBI chr 3:8,728,419...8,732,098
Ensembl chr 3:8,728,419...8,732,316 		JBrowse link
G Hey2 hairy/enhancer-of-split related with YRPW motif 2 involved_in IMP (MGI:3783952|PMID:17303760) BHF-UCL PMID:17303760 MGI:3783952 NCBI chr10:30,708,355...30,718,779
Ensembl chr10:30,708,355...30,718,797 		JBrowse link
G Heyl hairy/enhancer-of-split related with YRPW motif-like involved_in IGI (MGI:3783952|PMID:17303760) BHF-UCL PMID:17303760 MGI:3783952 NCBI chr 4:123,127,349...123,143,663
Ensembl chr 4:123,127,349...123,143,668 		JBrowse link
G Notch1 notch 1 involved_in IMP (MGI:3783952|PMID:17303760) BHF-UCL PMID:17303760 MGI:3783952 NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675 		JBrowse link
G Rtn4 reticulon 4 acts_upstream_of_or_within IMP (PMID:19156209) MGI PMID:19156209 NCBI chr11:29,642,898...29,694,414
Ensembl chr11:29,642,947...29,694,331 		JBrowse link
G Tbx3 T-box 3 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:119,808,600...119,822,789
Ensembl chr 5:119,808,734...119,822,789 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:186,354,984...186,441,504
Ensembl chr 1:186,354,989...186,438,186 		JBrowse link
G Tgfbr3 transforming growth factor, beta receptor III involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:107,254,433...107,437,495
Ensembl chr 5:107,254,436...107,437,495 		JBrowse link
G Wnt16 wingless-type MMTV integration site family, member 16 acts_upstream_of_or_within IMP (PMID:19156209) MGI PMID:19156209 NCBI chr 6:22,288,179...22,298,521
Ensembl chr 6:22,288,226...22,298,521 		JBrowse link
G Wnt2 wingless-type MMTV integration site family, member 2 acts_upstream_of_or_within IMP (PMID:20159597) MGI PMID:20159597 NCBI chr 6:17,988,939...18,032,771
Ensembl chr 6:17,988,939...18,030,584 		JBrowse link
endocardial cushion to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvrl1 activin A receptor, type II-like 1 NOT|involved_in IMP (MGI:2674189|PMID:12941632) BHF-UCL PMID:12941632 MGI:2674189 NCBI chr15:101,026,403...101,043,217
Ensembl chr15:101,026,403...101,043,217 		JBrowse link
G Eng endoglin NOT|involved_in IMP (MGI:2674189|PMID:12941632) BHF-UCL PMID:12941632 MGI:2674189 NCBI chr 2:32,536,607...32,572,681
Ensembl chr 2:32,536,607...32,572,681 		JBrowse link
G Has2 hyaluronan synthase 2 involved_in IMP (MGI:1861536|PMID:10930438) UniProt PMID:10930438 MGI:1861536 NCBI chr15:56,529,023...56,557,942
Ensembl chr15:56,529,023...56,557,935 		JBrowse link
endocardial cushion to mesenchymal transition involved in heart valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Efna1 ephrin A1 involved_in IMP (MGI:4847981|PMID:20960543) BHF-UCL PMID:20960543 MGI:4847981 NCBI chr 3:89,179,037...89,188,258
Ensembl chr 3:89,179,040...89,188,449 		JBrowse link
G Hey1 hairy/enhancer-of-split related with YRPW motif 1 acts_upstream_of_or_within IGI (PMID:15680351) MGI PMID:15680351 NCBI chr 3:8,728,419...8,732,098
Ensembl chr 3:8,728,419...8,732,316 		JBrowse link
G Hey2 hairy/enhancer-of-split related with YRPW motif 2 acts_upstream_of_or_within IGI (PMID:15680351) MGI PMID:15680351 NCBI chr10:30,708,355...30,718,779
Ensembl chr10:30,708,355...30,718,797 		JBrowse link
epicardial cell to mesenchymal cell transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja1 gap junction protein, alpha 1 involved_in TAS (MGI:4943617|PMID:20299672) DFLAT PMID:20299672 MGI:4943617 NCBI chr10:56,253,297...56,266,519
Ensembl chr10:56,253,426...56,278,609 		JBrowse link
G Tgfbr3 transforming growth factor, beta receptor III involved_in TAS (MGI:4943617|PMID:20299672) DFLAT PMID:20299672 MGI:4943617 NCBI chr 5:107,254,433...107,437,495
Ensembl chr 5:107,254,436...107,437,495 		JBrowse link
G Vangl2 VANGL planar cell polarity 2 involved_in TAS (MGI:4943617|PMID:20299672) DFLAT PMID:20299672 MGI:4943617 NCBI chr 1:171,828,527...171,856,532
Ensembl chr 1:171,828,527...171,856,011 		JBrowse link
epithelial to mesenchymal transition involved in cardiac fibroblast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir21a microRNA 21a involved_in ISO (PMID:23441172) BHF-UCL PMID:23441172 NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984 		JBrowse link
G Pdcd4 programmed cell death 4 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr19:53,880,662...53,926,024
Ensembl chr19:53,880,662...53,918,291 		JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 3:37,694,096...37,698,748
Ensembl chr 3:37,694,096...37,698,747 		JBrowse link
epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 NOT|involved_in IMP (MGI:3814273|PMID:18924235) BHF-UCL PMID:18924235 MGI:3814273 NCBI chr14:46,620,982...46,628,126
Ensembl chr14:46,620,977...46,628,126 		JBrowse link
G Eng endoglin involved_in IMP (MGI:4368063|PMID:19703439) BHF-UCL PMID:19703439 MGI:4368063 NCBI chr 2:32,536,607...32,572,681
Ensembl chr 2:32,536,607...32,572,681 		JBrowse link
G Fgf8 fibroblast growth factor 8 involved_in
acts_upstream_of_or_within		 IMP
IDA		 (MGI:4359139|PMID:19509466)
(PMID:21364285)		 BHF-UCL
MGI		 PMID:19509466 PMID:21364285 MGI:4359139 NCBI chr19:45,724,930...45,731,380
Ensembl chr19:45,725,237...45,731,354 		JBrowse link
G Hey1 hairy/enhancer-of-split related with YRPW motif 1 acts_upstream_of_or_within IGI (PMID:17303760) MGI PMID:17303760 NCBI chr 3:8,728,419...8,732,098
Ensembl chr 3:8,728,419...8,732,316 		JBrowse link
G Heyl hairy/enhancer-of-split related with YRPW motif-like acts_upstream_of_or_within IGI (PMID:17303760) MGI PMID:17303760 NCBI chr 4:123,127,349...123,143,663
Ensembl chr 4:123,127,349...123,143,668 		JBrowse link
G Msx1 msh homeobox 1 acts_upstream_of_or_within IGI (PMID:18667074) MGI PMID:18667074 NCBI chr 5:37,977,835...37,981,929
Ensembl chr 5:37,977,829...37,981,927 		JBrowse link
G Msx2 msh homeobox 2 acts_upstream_of_or_within IGI (PMID:18667074) MGI PMID:18667074 NCBI chr13:53,620,917...53,626,816
Ensembl chr13:53,620,920...53,627,110 		JBrowse link
G Notch1 notch 1 involved_in IMP (MGI:3027664|PMID:14701881) BHF-UCL PMID:14701881 MGI:3027664 NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in IMP (MGI:3027664|PMID:14701881) BHF-UCL PMID:14701881 MGI:3027664 NCBI chr 5:53,713,121...53,814,787
Ensembl chr 5:53,623,494...53,814,704 		JBrowse link
G Smad4 SMAD family member 4 involved_in IMP (MGI:4946551|PMID:21330551) BHF-UCL PMID:21330551 MGI:4946551 NCBI chr18:73,767,861...73,836,862
Ensembl chr18:73,772,080...73,836,851 		JBrowse link
G Snai1 snail family zinc finger 1 involved_in IGI (MGI:3808643|PMID:18663143) BHF-UCL PMID:18663143 MGI:3808643 NCBI chr 2:167,380,115...167,384,734
Ensembl chr 2:167,380,115...167,384,734 		JBrowse link
G Snai2 snail family zinc finger 2 acts_upstream_of_or_within IMP (PMID:18663143) MGI PMID:18663143 NCBI chr16:14,523,716...14,527,259
Ensembl chr16:14,523,716...14,527,249 		JBrowse link
G Tmem100 transmembrane protein 100 acts_upstream_of_or_within IMP (PMID:25318679) MGI PMID:25318679 NCBI chr11:89,921,174...89,927,334
Ensembl chr11:89,921,174...89,927,334 		JBrowse link
mesodermal to mesenchymal transition involved in gastrulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eomes eomesodermin involved_in IMP (MGI:3772748|PMID:18171685) UniProt PMID:18171685 MGI:3772748 NCBI chr 9:118,307,259...118,315,176
Ensembl chr 9:118,307,280...118,315,200 		JBrowse link
G Tasor transcription activation suppressor involved_in IMP (MGI:6109647|PMID:28839193) UniProt PMID:28839193 MGI:6109647 NCBI chr14:27,150,759...27,205,512
Ensembl chr14:27,150,791...27,205,512 		JBrowse link
G Wnt5a wingless-type MMTV integration site family, member 5A acts_upstream_of_or_within IGI (PMID:25813538) MGI PMID:25813538 NCBI chr14:28,224,962...28,249,405
Ensembl chr14:28,226,707...28,249,405 		JBrowse link
negative regulation of cardiac epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir19a microRNA 19a acts_upstream_of ISO (PMID:27098600) BHF-UCL PMID:27098600 NCBI chr14:115,281,432...115,281,513
Ensembl chr14:115,281,432...115,281,513 		JBrowse link
G Mir19b-1 microRNA 19b-1 acts_upstream_of ISO (PMID:27098600) BHF-UCL PMID:27098600 NCBI chr14:115,281,737...115,281,823
Ensembl chr14:115,281,737...115,281,823 		JBrowse link
G Mir19b-2 microRNA 19b-2 acts_upstream_of ISO (PMID:27098600) BHF-UCL PMID:27098600 NCBI chr  X:51,830,860...51,830,943
Ensembl chr  X:51,830,860...51,830,943 		JBrowse link
G Nog noggin involved_in IMP (MGI:3783944|PMID:17218603) BHF-UCL PMID:17218603 MGI:3783944 NCBI chr11:89,191,464...89,193,385
Ensembl chr11:89,191,464...89,193,158 		JBrowse link
negative regulation of epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipor1 adiponectin receptor 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:134,343,116...134,361,089
Ensembl chr 1:134,343,116...134,361,089 		JBrowse link
G Dab2ip disabled 2 interacting protein involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:35,448,285...35,621,006
Ensembl chr 2:35,448,278...35,621,006 		JBrowse link
G Dact3 dishevelled-binding antagonist of beta-catenin 3 acts_upstream_of_or_within IMP (PMID:23580654) MGI PMID:23580654 NCBI chr 7:16,609,242...16,621,226
Ensembl chr 7:16,609,242...16,621,387 		JBrowse link
G Efna1 ephrin A1 involved_in IMP (MGI:4847981|PMID:20960543) BHF-UCL PMID:20960543 MGI:4847981 NCBI chr 3:89,179,037...89,188,258
Ensembl chr 3:89,179,040...89,188,449 		JBrowse link
G Epha4 Eph receptor A4 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:77,343,819...77,491,763
Ensembl chr 1:77,343,822...77,491,725 		JBrowse link
G Foxa1 forkhead box A1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr12:57,585,750...57,594,815
Ensembl chr12:57,587,414...57,593,702 		JBrowse link
G Foxa2 forkhead box A2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:147,884,797...147,888,889
Ensembl chr 2:147,884,797...147,888,889 		JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:9,861,889...9,894,845
Ensembl chr 2:9,861,889...9,894,845 		JBrowse link
G Hpn hepsin involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 7:30,798,150...30,814,751
Ensembl chr 7:30,798,150...30,814,715 		JBrowse link
G Il17rd interleukin 17 receptor D involved_in IDA (MGI:6414689|PMID:25576668) UniProt PMID:25576668 MGI:6414689 NCBI chr14:26,760,990...26,829,243
Ensembl chr14:26,760,898...26,829,243 		JBrowse link
G Kat8 K(lysine) acetyltransferase 8 involved_in ISO (PMID:27292636) UniProt PMID:27292636 NCBI chr 7:127,511,689...127,525,010
Ensembl chr 7:127,511,688...127,525,009 		JBrowse link
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr18:68,065,345...68,393,621
Ensembl chr18:68,066,328...68,401,701 		JBrowse link
G Mad2l2 MAD2 mitotic arrest deficient-like 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:148,214,615...148,230,161
Ensembl chr 4:148,214,841...148,230,156 		JBrowse link
G Mark1 MAP/microtubule affinity regulating kinase 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:184,628,621...184,732,152
Ensembl chr 1:184,628,986...184,731,767 		JBrowse link
G Mir130a microRNA 130a acts_upstream_of ISO (PMID:30741461) BHF-UCL PMID:30741461 NCBI chr 2:84,571,459...84,571,522
Ensembl chr 2:84,571,459...84,571,522 		JBrowse link
G Mir142 microRNA 142 involved_in ISO (PMID:26572508) BHF-UCL PMID:26572508 NCBI chr11:87,647,690...87,647,753
Ensembl chr11:87,647,690...87,647,753 		JBrowse link
G Mir144 microRNA 144 acts_upstream_of ISO (PMID:27785072) DIBU PMID:27785072 NCBI chr11:77,963,831...77,963,896
Ensembl chr11:77,963,831...77,963,896 		JBrowse link
G Mir145a microRNA 145a acts_upstream_of ISO (PMID:24384875) BHF-UCL PMID:24384875 NCBI chr18:61,780,896...61,780,965
Ensembl chr18:61,780,896...61,780,965 		JBrowse link
G Mir149 microRNA 149 involved_in ISO (PMID:25916550) ARUK-UCL PMID:25916550 NCBI chr 1:92,778,100...92,778,165
Ensembl chr 1:92,778,100...92,778,165 		JBrowse link
G Mir18 microRNA 18 involved_in ISO (PMID:28131417) BHF-UCL PMID:28131417 NCBI chr14:115,281,283...115,281,378
Ensembl chr14:115,281,283...115,281,378 		JBrowse link
G Mir202 microRNA 202 acts_upstream_of ISO (PMID:28373289) BHF-UCL PMID:28373289 NCBI chr 7:139,537,602...139,537,673
Ensembl chr 7:139,537,602...139,537,673 		JBrowse link
G Mir204 microRNA 204 involved_in ISO (PMID:23221074) BHF-UCL PMID:23221074 NCBI chr19:22,727,969...22,728,036
Ensembl chr19:22,727,969...22,728,036 		JBrowse link
G Mir291b microRNA 291b involved_in ISO (PMID:21490602) BHF-UCL PMID:21490602 NCBI chr 7:3,268,156...3,268,234
Ensembl chr 7:3,268,156...3,268,234 		JBrowse link
G Mir29b-1 microRNA 29b-1 involved_in ISO (PMID:25032858) BHF-UCL PMID:25032858 NCBI chr 6:31,039,958...31,040,028
Ensembl chr 6:31,039,958...31,040,028 		JBrowse link
G Mir29b-2 microRNA 29b-2 involved_in ISO (PMID:25032858) BHF-UCL PMID:25032858 NCBI chr 1:194,719,348...194,719,428
Ensembl chr 1:194,719,348...194,719,428 		JBrowse link
G Mir302b microRNA 302b involved_in ISO (PMID:21490602) BHF-UCL PMID:21490602 NCBI chr 3:127,338,877...127,338,950
Ensembl chr 3:127,338,877...127,338,950 		JBrowse link
G Mir31 microRNA 31 ISO RGD PMID:23270756 RGD:13210526 NCBI chr 4:88,828,794...88,828,899
Ensembl chr 4:88,828,794...88,828,899 		JBrowse link
G Mir379 microRNA 379 involved_in ISO (PMID:26944318) BHF-UCL PMID:26944318 NCBI chr12:109,675,494...109,675,559
Ensembl chr12:109,675,494...109,675,559 		JBrowse link
G Nkx2-1 NK2 homeobox 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr12:56,578,741...56,583,570
Ensembl chr12:56,578,743...56,583,693 		JBrowse link
G Ovol2 ovo like zinc finger 2 involved_in IDA
IMP		 (MGI:6284898|PMID:28455959)
(MGI:5574425|PMID:24735879)		 ARUK-UCL
UniProt		 PMID:24735879 PMID:28455959 MGI:5574425 MGI:6284898 NCBI chr 2:144,147,095...144,174,000
Ensembl chr 2:144,147,095...144,174,066 		JBrowse link
G Pawr PRKC, apoptosis, WT1, regulator involved_in NAS (MGI:5648604|PMID:25472717) BHF-UCL PMID:25472717 MGI:5648604 NCBI chr10:108,168,050...108,250,708
Ensembl chr10:108,167,982...108,250,101 		JBrowse link
G Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:51,989,651...52,013,576
Ensembl chr11:51,989,508...52,018,605 		JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560 		JBrowse link
G Sdhaf2 succinate dehydrogenase complex assembly factor 2 acts_upstream_of_or_within IMP
ISO		 (PMID:23983127) MGI PMID:23983127 GO_REF:0000008 NCBI chr19:10,477,876...10,502,573
Ensembl chr19:10,477,898...10,503,506 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 8:23,901,401...23,939,648
Ensembl chr 8:23,901,518...23,939,648 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 3:83,673,628...83,681,621
Ensembl chr 3:83,673,628...83,681,623 		JBrowse link
G Spred1 sprouty protein with EVH-1 domain 1, related sequence involved_in IDA (MGI:6414689|PMID:25576668) UniProt PMID:25576668 MGI:6414689 NCBI chr 2:116,951,576...117,012,760
Ensembl chr 2:116,951,855...117,012,760 		JBrowse link
G Spred2 sprouty-related EVH1 domain containing 2 involved_in IDA (MGI:6414689|PMID:25576668) UniProt PMID:25576668 MGI:6414689 NCBI chr11:19,874,442...19,974,026
Ensembl chr11:19,874,375...19,974,026 		JBrowse link
G Spred3 sprouty-related EVH1 domain containing 3 involved_in IDA (MGI:6414689|PMID:25576668) UniProt PMID:25576668 MGI:6414689 NCBI chr 7:28,857,208...28,869,286
Ensembl chr 7:28,858,254...28,869,836 		JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 involved_in IDA (MGI:6414689|PMID:25576668) UniProt PMID:25576668 MGI:6414689 NCBI chr 3:37,694,096...37,698,748
Ensembl chr 3:37,694,096...37,698,747 		JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 involved_in IDA (MGI:6414689|PMID:25576668) UniProt PMID:25576668 MGI:6414689 NCBI chr14:106,129,381...106,134,559
Ensembl chr14:106,129,381...106,134,253 		JBrowse link
G Tgfbr3 transforming growth factor, beta receptor III acts_upstream_of_or_within IMP (PMID:17823118) MGI PMID:17823118 NCBI chr 5:107,254,433...107,437,495
Ensembl chr 5:107,254,436...107,437,495 		JBrowse link
G Trim62 tripartite motif-containing 62 acts_upstream_of_or_within IMP (PMID:24890125) MGI PMID:24890125 NCBI chr 4:128,777,837...128,805,119
Ensembl chr 4:128,777,373...128,805,121 		JBrowse link
G Tsc2 TSC complex subunit 2 involved_in ISO RGD
MGI		 PMID:20813961 GO_REF:0000096 MGI:4417868 RGD:11568680 NCBI chr17:24,814,788...24,851,607
Ensembl chr17:24,814,790...24,851,604 		JBrowse link
G Usf3 upstream transcription factor family member 3 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr16:43,993,566...44,047,828
Ensembl chr16:43,993,609...44,047,828 		JBrowse link
G Vasn vasorin involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr16:4,457,809...4,469,030
Ensembl chr16:4,457,805...4,468,666 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in IMP (MGI:5502250|PMID:23863481) BHF-UCL PMID:23863481 MGI:5502250 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
G Zfp750 zinc finger protein 750 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:121,401,802...121,410,168
Ensembl chr11:121,401,804...121,410,159 		JBrowse link
negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb2 transforming growth factor, beta 2 involved_in IMP (MGI:3830400|PMID:19161227) BHF-UCL PMID:19161227 MGI:3830400 NCBI chr 1:186,354,984...186,441,504
Ensembl chr 1:186,354,989...186,438,186 		JBrowse link
negative regulation of neural crest formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fuz fuzzy planar cell polarity protein involved_in IMP (MGI:5498583|PMID:23806618) UniProt PMID:23806618 MGI:5498583 NCBI chr 7:44,545,517...44,552,053
Ensembl chr 7:44,545,503...44,552,055 		JBrowse link
neural crest cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 involved_in IMP (PMID:23933587) MGI PMID:23933587 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466 		JBrowse link
G Ednra endothelin receptor type A involved_in IMP (PMID:23933587)
(PMID:17294360)		 MGI PMID:17294360 PMID:23933587 NCBI chr 8:78,389,658...78,451,081
Ensembl chr 8:78,389,660...78,451,093 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 acts_upstream_of_or_within IMP (PMID:20130188) MGI PMID:20130188 NCBI chr 8:23,901,401...23,939,648
Ensembl chr 8:23,901,518...23,939,648 		JBrowse link
neural crest cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsc goosecoid homeobox involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr12:104,437,468...104,439,495
Ensembl chr12:104,437,468...104,439,589 		JBrowse link
neural crest formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrd chordin involved_in IMP (PMID:17685487) MGI PMID:17685487 NCBI chr16:20,551,528...20,561,132
Ensembl chr16:20,551,877...20,561,134 		JBrowse link
G Kbtbd8 kelch repeat and BTB (POZ) domain containing 8 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 6:95,094,861...95,106,774
Ensembl chr 6:95,094,221...95,106,771 		JBrowse link
G Klhl12 kelch-like 12 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:134,383,269...134,418,611
Ensembl chr 1:134,383,269...134,418,756 		JBrowse link
G Lrp6 low density lipoprotein receptor-related protein 6 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 6:134,423,439...134,543,876
Ensembl chr 6:134,423,439...134,543,928 		JBrowse link
G Nolc1 nucleolar and coiled-body phosphoprotein 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr19:46,064,286...46,073,982
Ensembl chr19:46,064,302...46,073,969 		JBrowse link
G Pdcd6 programmed cell death 6 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr13:74,451,240...74,465,445
Ensembl chr13:74,451,628...74,465,699 		JBrowse link
G Pef1 penta-EF hand domain containing 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:130,001,349...130,021,927
Ensembl chr 4:129,996,351...130,021,928 		JBrowse link
G Tcof1 treacle ribosome biogenesis factor 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr18:60,946,827...60,982,055
Ensembl chr18:60,946,827...60,982,043 		JBrowse link
positive regulation of cardiac epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor, type 1 involved_in IMP (MGI:3610266|PMID:16140292) BHF-UCL PMID:16140292 MGI:3610266 NCBI chr 2:58,336,450...58,456,840
Ensembl chr 2:58,278,656...58,457,169 		JBrowse link
G Emp2 epithelial membrane protein 2 involved_in IMP (MGI:6443292|PMID:30773261) UniProt PMID:30773261 MGI:6443292 NCBI chr16:10,099,613...10,131,832
Ensembl chr16:10,099,613...10,131,832 		JBrowse link
G Jag1 jagged 1 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 2:136,923,371...136,958,440
Ensembl chr 2:136,923,376...136,958,564 		JBrowse link
G Notch1 notch 1 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in IMP (MGI:5300829|PMID:22186728) UniProt PMID:22186728 MGI:5300829 NCBI chr 1:186,354,984...186,441,504
Ensembl chr 1:186,354,989...186,438,186 		JBrowse link
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Twist1 twist basic helix-loop-helix transcription factor 1 involved_in IDA (MGI:4838344|PMID:20804746) BHF-UCL PMID:20804746 MGI:4838344 NCBI chr12:34,007,670...34,009,830
Ensembl chr12:34,007,670...34,009,828 		JBrowse link
positive regulation of epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam8 a disintegrin and metallopeptidase domain 8 involved_in IMP (MGI:7444872|PMID:34615811) UniProt PMID:34615811 MGI:7444872 NCBI chr 7:139,558,845...139,573,016
Ensembl chr 7:139,558,845...139,572,475 		JBrowse link
G Ager advanced glycosylation end product-specific receptor involved_in ISO RGD
MGI		 PMID:21743278 GO_REF:0000096 MGI:4417868 RGD:7243870 NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910 		JBrowse link
G Agt angiotensinogen involved_in IMP (MGI:7444872|PMID:34615811) UniProt PMID:34615811 MGI:7444872 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445 		JBrowse link
G Alx1 ALX homeobox 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:102,834,564...102,865,501
Ensembl chr10:102,834,568...102,866,076 		JBrowse link
G Axin2 axin 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:108,808,687...108,841,609
Ensembl chr11:108,811,175...108,841,609 		JBrowse link
G Bambi BMP and activin membrane-bound inhibitor involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr18:3,507,011...3,516,404
Ensembl chr18:3,507,923...3,516,404 		JBrowse link
G Bcl9l B cell CLL/lymphoma 9-like involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:44,394,103...44,423,203
Ensembl chr 9:44,394,122...44,423,193 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within		 ISO
IMP		 (PMID:16314491) MGI PMID:16314491 GO_REF:0000119 MGI:4834177 NCBI chr 2:133,394,079...133,404,816
Ensembl chr 2:133,394,079...133,404,805 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IGI (MGI:5502250|PMID:23863481) BHF-UCL PMID:23863481 MGI:5502250 NCBI chr14:46,620,982...46,628,126
Ensembl chr14:46,620,977...46,628,126 		JBrowse link
G Bmp7 bone morphogenetic protein 7 involved_in IGI (MGI:5502250|PMID:23863481) BHF-UCL PMID:23863481 MGI:5502250 NCBI chr 2:172,709,805...172,782,114
Ensembl chr 2:172,709,805...172,782,114 		JBrowse link
G Col1a1 collagen, type I, alpha 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868 		JBrowse link
G Crb2 crumbs family member 2 involved_in IMP (MGI:5296388|PMID:22072575), (MGI:5823085|PMID:27870829) UniProt PMID:22072575 PMID:27870829 MGI:5296388 MGI:5823085 NCBI chr 2:37,666,238...37,689,115
Ensembl chr 2:37,666,261...37,689,115 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of_or_within		 TAS
ISO		 (MGI:4943617|PMID:20299672) DFLAT
MGI		 PMID:20299672 GO_REF:0000008 MGI:4943617 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573 		JBrowse link
G Dab2 disabled 2, mitogen-responsive phosphoprotein involved_in IMP
IBA
ISO		 (MGI:5442513|PMID:15734730) UniProt
GO_Central
MGI		 PMID:15734730 GO_REF:0000033 GO_REF:0000119 MGI:4834177 MGI:5442513 NCBI chr15:6,329,269...6,470,196
Ensembl chr15:6,329,269...6,470,193 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 6:47,507,208...47,613,843
Ensembl chr 6:47,507,073...47,572,275 		JBrowse link
G Fermt2 fermitin family member 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr14:45,696,252...45,767,767
Ensembl chr14:45,696,252...45,767,575 		JBrowse link
G Foxc1 forkhead box C1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr13:31,990,629...31,994,618
Ensembl chr13:31,990,616...31,996,459 		JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 (I blood group) involved_in IMP
ISO		 (MGI:5545971|PMID:21750175) UniProt
MGI		 PMID:21750175 GO_REF:0000119 MGI:4834177 MGI:5545971 NCBI chr13:41,013,417...41,114,368
Ensembl chr13:41,013,230...41,114,368 		JBrowse link
G Glipr2 GLI pathogenesis-related 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:43,957,702...43,979,118
Ensembl chr 4:43,957,401...43,979,118 		JBrowse link
G Hdac2 histone deacetylase 2 involved_in ISO RGD
MGI		 PMID:19553350 GO_REF:0000096 MGI:4417868 RGD:9590229 NCBI chr10:36,850,293...36,877,885
Ensembl chr10:36,850,540...36,877,885 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il6 interleukin 6 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Isl1 ISL1 transcription factor, LIM/homeodomain involved_in ISO MGI
RGD		 PMID:23270756 GO_REF:0000096 MGI:4417868 RGD:13210526 NCBI chr13:116,434,806...116,446,224
Ensembl chr13:116,434,817...116,446,225 		JBrowse link
G Kdm1a lysine (K)-specific demethylase 1A involved_in ISO (PMID:27292636) UniProt PMID:27292636 NCBI chr 4:136,277,844...136,330,127
Ensembl chr 4:136,277,851...136,330,034 		JBrowse link
G Lef1 lymphoid enhancer binding factor 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 3:130,903,972...131,018,006
Ensembl chr 3:130,904,120...131,018,005 		JBrowse link
G Loxl2 lysyl oxidase-like 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr14:69,846,085...69,933,283
Ensembl chr14:69,846,517...69,933,283 		JBrowse link
G Lrg1 leucine-rich alpha-2-glycoprotein 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr17:56,426,678...56,428,946
Ensembl chr17:56,426,678...56,429,001 		JBrowse link
G Mad2l2 MAD2 mitotic arrest deficient-like 2 involved_in ISO TGFb1 RGD
MGI		 PMID:27488450 GO_REF:0000096 MGI:4417868 RGD:152995505 NCBI chr 4:148,214,615...148,230,161
Ensembl chr 4:148,214,841...148,230,156 		JBrowse link
G Mdk midkine involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:91,760,149...91,762,348
Ensembl chr 2:91,760,150...91,762,642 		JBrowse link
G Mir21a microRNA 21a involved_in ISO (PMID:24887517) BHF-UCL PMID:24887517 NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984 		JBrowse link
G Mir221 microRNA 221 involved_in ISO (PMID:21673316) BHF-UCL PMID:21673316 NCBI chr  X:19,012,533...19,012,627
Ensembl chr  X:19,012,533...19,012,627 		JBrowse link
G Mir222 microRNA 222 involved_in ISO (PMID:21673316) BHF-UCL PMID:21673316 NCBI chr  X:19,013,132...19,013,210
Ensembl chr  X:19,013,132...19,013,210 		JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140 		JBrowse link
G Myocd myocardin involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr11:65,064,434...65,160,821
Ensembl chr11:65,067,387...65,160,815 		JBrowse link
G Notch1 notch 1 involved_in IMP (MGI:4837019|PMID:20890042) BHF-UCL PMID:20890042 MGI:4837019 NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675 		JBrowse link
G Pdpn podoplanin involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:142,993,979...143,026,134
Ensembl chr 4:142,994,001...143,026,134 		JBrowse link
G Ptk2 PTK2 protein tyrosine kinase 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr15:73,076,951...73,297,192
Ensembl chr15:73,076,951...73,295,129 		JBrowse link
G Rgcc regulator of cell cycle involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr14:79,526,190...79,539,075
Ensembl chr14:79,526,196...79,539,085 		JBrowse link
G Sdcbp syndecan binding protein involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:6,365,713...6,396,120
Ensembl chr 4:6,365,650...6,408,423 		JBrowse link
G Serpinb3d serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3D involved_in ISO (PMID:20527027) UniProt PMID:20527027 NCBI chr 1:107,005,893...107,011,210
Ensembl chr 1:107,005,897...107,011,236 		JBrowse link
G Smad2 SMAD family member 2 involved_in IMP (MGI:2683382|PMID:14691138) BHF-UCL PMID:14691138 MGI:2683382 NCBI chr18:76,369,898...76,444,819
Ensembl chr18:76,374,651...76,444,034 		JBrowse link
G Smad3 SMAD family member 3 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:63,554,048...63,665,276
Ensembl chr 9:63,554,049...63,665,276 		JBrowse link
G Smad4 SMAD family member 4 involved_in IMP (MGI:2683382|PMID:14691138) BHF-UCL PMID:14691138 MGI:2683382 NCBI chr18:73,767,861...73,836,862
Ensembl chr18:73,772,080...73,836,851 		JBrowse link
G Snai1 snail family zinc finger 1 involved_in IMP
ISO		 (MGI:4837019|PMID:20890042), (MGI:5548026|PMID:24239292) UniProt
MGI		 PMID:20890042 PMID:24239292 GO_REF:0000119 MGI:4834177 MGI:4837019 MGI:5548026 NCBI chr 2:167,380,115...167,384,734
Ensembl chr 2:167,380,115...167,384,734 		JBrowse link
G Tbx20 T-box 20 involved_in IMP (MGI:5299248|PMID:21983003) BHF-UCL PMID:21983003 MGI:5299248 NCBI chr 9:24,632,108...24,685,580
Ensembl chr 9:24,629,434...24,685,599 		JBrowse link
G Tcf7l2 transcription factor 7 like 2, T cell specific, HMG box involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr19:55,730,227...55,922,091
Ensembl chr19:55,730,252...55,922,086 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in
acts_upstream_of_or_within		 ISO
IDA		 (PMID:18794329) MGI PMID:18794329 GO_REF:0000119 MGI:4834177 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:127,845,963...127,852,884
Ensembl chr 7:127,845,984...127,854,871 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:186,354,984...186,441,504
Ensembl chr 1:186,354,989...186,438,186 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 involved_in IMP
ISO		 (MGI:2683382|PMID:14691138) BHF-UCL
MGI		 PMID:14691138 GO_REF:0000119 MGI:2683382 MGI:4834177 NCBI chr12:86,103,517...86,125,815
Ensembl chr12:86,103,519...86,125,815 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor I involved_in IGI (MGI:3820811|PMID:18718461) BHF-UCL PMID:18718461 MGI:3820811 NCBI chr 4:47,353,258...47,414,926
Ensembl chr 4:47,353,222...47,414,931 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor II involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:115,916,763...116,004,431
Ensembl chr 9:115,913,361...116,004,428 		JBrowse link
G Twist1 twist basic helix-loop-helix transcription factor 1 involved_in IMP
ISO		 (MGI:4838344|PMID:20804746), (MGI:5284765|PMID:18297062), (MGI:5284780|PMID:17332324) BHF-UCL
MGI		 PMID:17332324 PMID:18297062 PMID:20804746 GO_REF:0000119 MGI:4834177 MGI:4838344 MGI:5284765 MGI:5284780 NCBI chr12:34,007,670...34,009,830
Ensembl chr12:34,007,670...34,009,828 		JBrowse link
G Wwtr1 WW domain containing transcription regulator 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 3:57,363,065...57,483,331
Ensembl chr 3:57,363,070...57,483,331 		JBrowse link
G Zfp703 zinc finger protein 703 involved_in IDA (MGI:4940410|PMID:21317240) UniProt PMID:21317240 MGI:4940410 NCBI chr 8:27,467,364...27,471,490
Ensembl chr 8:27,467,353...27,471,489 		JBrowse link
positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eng endoglin involved_in IMP (MGI:4368063|PMID:19703439) BHF-UCL PMID:19703439 MGI:4368063 NCBI chr 2:32,536,607...32,572,681
Ensembl chr 2:32,536,607...32,572,681 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in IMP (MGI:3830400|PMID:19161227) BHF-UCL PMID:19161227 MGI:3830400 NCBI chr 1:186,354,984...186,441,504
Ensembl chr 1:186,354,989...186,438,186 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor I involved_in IMP (MGI:3820811|PMID:18718461) BHF-UCL PMID:18718461 MGI:3820811 NCBI chr 4:47,353,258...47,414,926
Ensembl chr 4:47,353,222...47,414,931 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor II involved_in IMP (MGI:3801267|PMID:17050629) BHF-UCL PMID:17050629 MGI:3801267 NCBI chr 9:115,916,763...116,004,431
Ensembl chr 9:115,913,361...116,004,428 		JBrowse link
regulation of epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aplf aprataxin and PNKP like factor involved_in IMP (MGI:6780835|PMID:33277378) UniProt PMID:33277378 MGI:6780835 NCBI chr 6:87,605,407...87,649,244
Ensembl chr 6:87,605,406...87,649,175 		JBrowse link
G Clasp1 CLIP associating protein 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:118,314,976...118,537,192
Ensembl chr 1:118,316,788...118,540,408 		JBrowse link
G Clasp2 CLIP associating protein 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:113,567,776...113,748,765
Ensembl chr 9:113,570,541...113,748,750 		JBrowse link
G Dag1 dystroglycan 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:108,082,060...108,141,176
Ensembl chr 9:108,081,833...108,141,157 		JBrowse link
G Ell3 elongation factor RNA polymerase II-like 3 involved_in IMP (MGI:5438719|PMID:22768269) UniProt PMID:22768269 MGI:5438719 NCBI chr 2:121,269,508...121,273,082
Ensembl chr 2:121,269,491...121,274,759 		JBrowse link
G Epha3 Eph receptor A3 involved_in IMP (MGI:3703403|PMID:17046737) UniProt PMID:17046737 MGI:3703403 NCBI chr16:63,363,895...63,684,538
Ensembl chr16:63,363,897...63,684,538 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:113,579,020...113,588,993
Ensembl chr 2:113,576,509...113,588,991 		JBrowse link
G Mcrip1 MAPK regulated corepressor interacting protein 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:120,433,714...120,440,553
Ensembl chr11:120,433,714...120,440,553 		JBrowse link
G Phldb1 pleckstrin homology like domain, family B, member 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:44,597,605...44,649,800
Ensembl chr 9:44,597,601...44,646,495 		JBrowse link
G Phldb2 pleckstrin homology like domain, family B, member 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr16:45,566,593...45,773,961
Ensembl chr16:45,566,606...45,773,961 		JBrowse link
G Pofut2 protein O-fucosyltransferase 2 acts_upstream_of_or_within IMP (PMID:20637190) MGI PMID:20637190 NCBI chr10:77,095,056...77,105,420
Ensembl chr10:77,095,052...77,105,409 		JBrowse link
G Qki quaking, KH domain containing RNA binding involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr17:10,425,480...10,538,706
Ensembl chr17:10,421,530...10,538,783 		JBrowse link
G Smad7 SMAD family member 7 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr18:75,500,436...75,529,006
Ensembl chr18:75,500,600...75,529,006 		JBrowse link
G Tbx20 T-box 20 involved_in NAS (MGI:3604925|PMID:15843409) BHF-UCL PMID:15843409 MGI:3604925 NCBI chr 9:24,632,108...24,685,580
Ensembl chr 9:24,629,434...24,685,599 		JBrowse link
G Tiam1 T cell lymphoma invasion and metastasis 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr16:89,583,999...89,942,488
Ensembl chr16:89,583,999...89,940,657 		JBrowse link
regulation of epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb1 transforming growth factor, beta 1 NOT|involved_in IMP (MGI:3830400|PMID:19161227) BHF-UCL PMID:19161227 MGI:3830400 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 NOT|involved_in IMP (MGI:3830400|PMID:19161227) BHF-UCL PMID:19161227 MGI:3830400 NCBI chr12:86,103,517...86,125,815
Ensembl chr12:86,103,519...86,125,815 		JBrowse link
regulation of neural crest cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor, type 1A NOT|involved_in IMP (MGI:3040576|PMID:15073157) BHF-UCL PMID:15073157 MGI:3040576 NCBI chr14:34,133,018...34,225,335
Ensembl chr14:34,132,691...34,225,298 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28576
    cellular process 17546
      cellular developmental process 5064
        cell differentiation 5063
          mesenchymal cell differentiation 281
            epithelial to mesenchymal transition 193
              cardiac epithelial to mesenchymal transition + 40
              clearance of cells from fusion plate by epithelial to mesenchymal transition 0
              epicardial cell to mesenchymal cell transition 3
              mesodermal to mesenchymal transition involved in gastrulation + 3
              negative regulation of epithelial to mesenchymal transition + 54
              neural crest formation + 14
              positive regulation of epithelial to mesenchymal transition + 59
              regulation of epithelial to mesenchymal transition + 126
Path 2
Term Annotations click to browse term
  biological_process 28576
    developmental process 7377
      anatomical structure development 6849
        tissue development 2361
          mesenchyme development 342
            mesenchymal cell differentiation 281
              epithelial to mesenchymal transition 193
                cardiac epithelial to mesenchymal transition + 40
                clearance of cells from fusion plate by epithelial to mesenchymal transition 0
                epicardial cell to mesenchymal cell transition 3
                mesodermal to mesenchymal transition involved in gastrulation + 3
                negative regulation of epithelial to mesenchymal transition + 54
                neural crest formation + 14
                positive regulation of epithelial to mesenchymal transition + 59
                regulation of epithelial to mesenchymal transition + 126
paths to the root