Biological Process
| activation of MAPKK activity | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| anatomical structure formation involved in morphogenesis | | IGI | MGI:MGI:104327 | 2290270 | MGI:MGI:3654583|PMID:16916379 | MGI | MGI:MGI:3654583 PMID:16916379 |
| angiogenesis | | IMP | MGI:MGI:3042751 | 2290270 | MGI:MGI:3039210|PMID:15070745 | MGI | MGI:MGI:3039210 PMID:15070745 |
| anterior/posterior axis specification | | IGI | MGI:MGI:104903 | 2290270 | MGI:MGI:1889107|PMID:10964473 | MGI | MGI:MGI:1889107 PMID:10964473 |
| blood vessel development | | IDA | | 2290270 | MGI:MGI:48668|PMID:1521591 | MGI | MGI:MGI:48668 PMID:1521591 |
| blood vessel endothelial cell proliferation involved in sprouting angiogenesis | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| BMP signaling pathway | | IGI | MGI:MGI:2679262 | 2290270 | MGI:MGI:3590430|PMID:15975920 | MGI | MGI:MGI:3590430 PMID:15975920 |
| BMP signaling pathway | | IDA | | 2290270 | MGI:MGI:3718174|PMID:17472960 | MGI | MGI:MGI:3718174 PMID:17472960 |
| BMP signaling pathway | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:3718174|PMID:17472960 | MGI | MGI:MGI:3718174 PMID:17472960 |
| BMP signaling pathway | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| BMP signaling pathway | | IDA | | 2290270 | MGI:MGI:2681048|PMID:14623234 | MGI | MGI:MGI:2681048 PMID:14623234 |
| BMP signaling pathway involved in heart induction | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| BMP signaling pathway involved in nephric duct formation | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| BMP signaling pathway involved in renal system segmentation | | IMP | | 2290270 | MGI:MGI:3710018|PMID:17442697 | UniProtKB | MGI:MGI:3710018 PMID:17442697 |
| BMP signaling pathway involved in ureter morphogenesis | | IDA | | 2290270 | MGI:MGI:3710018|PMID:17442697 | UniProtKB | MGI:MGI:3710018 PMID:17442697 |
| bone development | | IDA | | 2290270 | MGI:MGI:63654|PMID:8358941 | MGI | MGI:MGI:63654 PMID:8358941 |
| branching involved in prostate gland morphogenesis | | IMP | MGI:MGI:1857137 | 2290270 | MGI:MGI:1934513|PMID:11401393 | MGI | MGI:MGI:1934513 PMID:11401393 |
| branching involved in ureteric bud morphogenesis | | IGI | MGI:MGI:1344337 | 2290270 | MGI:MGI:3714585|PMID:17522159 | MGI | MGI:MGI:3714585 PMID:17522159 |
| branching involved in ureteric bud morphogenesis | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| branching morphogenesis of an epithelial tube | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| bronchus development | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:81070|PMID:8674409 | MGI | MGI:MGI:81070 PMID:8674409 |
| bud dilation involved in lung branching | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:81070|PMID:8674409 | MGI | MGI:MGI:81070 PMID:8674409 |
| bud elongation involved in lung branching | | IDA | | 2290270 | MGI:MGI:3788965|PMID:18367557 | MGI | MGI:MGI:3788965 PMID:18367557 |
| camera-type eye development | | IGI | MGI:MGI:2137520 | 2290270 | MGI:MGI:3043486|PMID:14681194 | MGI | MGI:MGI:3043486 PMID:14681194 |
| camera-type eye development | | IMP | MGI:MGI:1857137 | 2290270 | MGI:MGI:1095762|PMID:9268572 | MGI | MGI:MGI:1095762 PMID:9268572 |
| camera-type eye morphogenesis | | IMP | MGI:MGI:88180 | 2290270 | MGI:MGI:1095762|PMID:9268572 | MGI | MGI:MGI:1095762 PMID:9268572 |
| cartilage development | | IEA | UniProtKB-KW:KW-0891 | 2290270 | MGI:MGI:1354194 | UniProtKB | MGI:MGI:1354194 |
| cell differentiation | | IEA | UniProtKB-KW:KW-0221 | 2290270 | MGI:MGI:1354194 | UniProtKB | MGI:MGI:1354194 |
| cell fate commitment | | IDA | | 2290270 | MGI:MGI:2429473|PMID:12421925 | MGI | MGI:MGI:2429473 PMID:12421925 |
| cellular response to dexamethasone stimulus | | ISO | UniProtKB:Q06826 | 2290270 | MGI:MGI:4417868 | RGD | MGI:MGI:4417868 |
| cellular response to growth factor stimulus | | IDA | | 2290270 | MGI:MGI:69105|PMID:7848824 | MGI | MGI:MGI:69105 PMID:7848824 |
| chondrocyte differentiation | | IMP | | 2290270 | MGI:MGI:4418577|PMID:20059955 | UniProtKB | MGI:MGI:4418577 PMID:20059955 |
| common-partner SMAD protein phosphorylation | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| cranial suture morphogenesis | | IDA | | 2290270 | MGI:MGI:1203304|PMID:9477322 | MGI | MGI:MGI:1203304 PMID:9477322 |
| deltoid tuberosity development | | IMP | | 2290270 | MGI:MGI:4418577|PMID:20059955 | UniProtKB | MGI:MGI:4418577 PMID:20059955 |
| dorsal/ventral neural tube patterning | | IDA | | 2290270 | MGI:MGI:3046395|PMID:15218525 | MGI | MGI:MGI:3046395 PMID:15218525 |
| embryonic cranial skeleton morphogenesis | | IMP | MGI:MGI:1857137 | 2290270 | MGI:MGI:1095762|PMID:9268572 | MGI | MGI:MGI:1095762 PMID:9268572 |
| embryonic digit morphogenesis | | IGI | MGI:MGI:108359|MGI:MGI:95729 | 2290270 | MGI:MGI:1095762|PMID:9268572 | MGI | MGI:MGI:1095762 PMID:9268572 |
| embryonic hindlimb morphogenesis | | IGI | MGI:MGI:104903 | 2290270 | MGI:MGI:1889107|PMID:10964473 | MGI | MGI:MGI:1889107 PMID:10964473 |
| embryonic limb morphogenesis | | IGI | MGI:MGI:103302 | 2290270 | MGI:MGI:1270933|PMID:9664686 | MGI | MGI:MGI:1270933 PMID:9664686 |
| embryonic limb morphogenesis | | IMP | MGI:MGI:1857137 | 2290270 | MGI:MGI:1270933|PMID:9664686 | MGI | MGI:MGI:1270933 PMID:9664686 |
| embryonic morphogenesis | | IMP | MGI:MGI:3041440|MGI:MGI:2176835 | 2290270 | MGI:MGI:3574741|PMID:15716346 | MGI | MGI:MGI:3574741 PMID:15716346 |
| embryonic skeletal joint morphogenesis | | IGI | MGI:MGI:103302 | 2290270 | MGI:MGI:1270933|PMID:9664686 | MGI | MGI:MGI:1270933 PMID:9664686 |
| embryonic skeletal joint morphogenesis | | IMP | MGI:MGI:1857137 | 2290270 | MGI:MGI:1270933|PMID:9664686 | MGI | MGI:MGI:1270933 PMID:9664686 |
| embryonic skeletal system development | | IMP | MGI:MGI:2158495 | 2290270 | MGI:MGI:3640733|PMID:16712836 | MGI | MGI:MGI:3640733 PMID:16712836 |
| embryonic skeletal system morphogenesis | | IMP | MGI:MGI:2158495 | 2290270 | MGI:MGI:3640733|PMID:16712836 | MGI | MGI:MGI:3640733 PMID:16712836 |
| endochondral ossification | | IMP | | 2290270 | MGI:MGI:4418577|PMID:20059955 | UniProtKB | MGI:MGI:4418577 PMID:20059955 |
| epithelial cell proliferation involved in lung morphogenesis | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:81070|PMID:8674409 | MGI | MGI:MGI:81070 PMID:8674409 |
| epithelial tube branching involved in lung morphogenesis | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:81070|PMID:8674409 | MGI | MGI:MGI:81070 PMID:8674409 |
| epithelial-mesenchymal cell signaling | | IDA | | 2290270 | MGI:MGI:83888|PMID:8104708 | MGI | MGI:MGI:83888 PMID:8104708 |
| epithelium development | | IDA | | 2290270 | MGI:MGI:83672|PMID:8898217 | MGI | MGI:MGI:83672 PMID:8898217 |
| erythrocyte differentiation | | IDA | | 2290270 | MGI:MGI:3578483|PMID:15591122 | MGI | MGI:MGI:3578483 PMID:15591122 |
| eye development | NOT | IGI | UniProtKB:P23359 | 2290270 | MGI:MGI:3610441|PMID:16154126 | UniProtKB | MGI:MGI:3610441 PMID:16154126 |
| forebrain development | | IMP | MGI:MGI:1857137 | 2290270 | MGI:MGI:1095762|PMID:9268572 | MGI | MGI:MGI:1095762 PMID:9268572 |
| forebrain development | | IGI | MGI:MGI:2137520 | 2290270 | MGI:MGI:3043486|PMID:14681194 | MGI | MGI:MGI:3043486 PMID:14681194 |
| germ cell development | | IMP | MGI:MGI:1857137 | 2290270 | MGI:MGI:3050161|PMID:15289457 | MGI | MGI:MGI:3050161 PMID:15289457 |
| glomerular capillary formation | | IMP | | 2290270 | MGI:MGI:3849375|PMID:18272846 | UniProtKB | MGI:MGI:3849375 PMID:18272846 |
| growth | | IEA | InterPro:IPR001111 | 2290270 | MGI:MGI:2152098 | UniProtKB | MGI:MGI:2152098 |
| heart development | | IMP | MGI:MGI:2181190 | 2290270 | MGI:MGI:2677659|PMID:12975322 | MGI | MGI:MGI:2677659 PMID:12975322 |
| heart development | | IMP | MGI:MGI:3042751 | 2290270 | MGI:MGI:3039210|PMID:15070745 | MGI | MGI:MGI:3039210 PMID:15070745 |
| hematopoietic progenitor cell differentiation | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| hematopoietic progenitor cell differentiation | | IDA | | 2290270 | MGI:MGI:70235|PMID:7799920 | MGI | MGI:MGI:70235 PMID:7799920 |
| inner ear receptor cell differentiation | | IGI | MGI:MGI:95524 | 2290270 | MGI:MGI:3714221|PMID:17555714 | MGI | MGI:MGI:3714221 PMID:17555714 |
| intermediate mesodermal cell differentiation | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| kidney development | | IMP | MGI:MGI:1857137 | 2290270 | MGI:MGI:1095762|PMID:9268572 | MGI | MGI:MGI:1095762 PMID:9268572 |
| kidney development | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| kidney development | | IGI | UniProtKB:P23359 | 2290270 | MGI:MGI:3610441|PMID:16154126 | UniProtKB | MGI:MGI:3610441 PMID:16154126 |
| lens induction in camera-type eye | | IMP | MGI:MGI:1857137 | 2290270 | MGI:MGI:1316914|PMID:9851982 | MGI | MGI:MGI:1316914 PMID:9851982 |
| lung alveolus development | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:81070|PMID:8674409 | MGI | MGI:MGI:81070 PMID:8674409 |
| lung development | | IMP | MGI:MGI:2181190|MGI:MGI:3574949 | 2290270 | MGI:MGI:3618437|PMID:16414041 | MGI | MGI:MGI:3618437 PMID:16414041 |
| lung morphogenesis | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:81070|PMID:8674409 | MGI | MGI:MGI:81070 PMID:8674409 |
| lymphoid progenitor cell differentiation | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| macrophage differentiation | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| mammary gland formation | | IMP | | 2290270 | MGI:MGI:3695659|PMID:17071745 | MGI | MGI:MGI:3695659 PMID:17071745 |
| mesenchymal cell differentiation involved in kidney development | | IMP | | 2290270 | MGI:MGI:3710018|PMID:17442697 | UniProtKB | MGI:MGI:3710018 PMID:17442697 |
| mesenchymal cell differentiation involved in renal system development | | IMP | | 2290270 | MGI:MGI:3710018|PMID:17442697 | UniProtKB | MGI:MGI:3710018 PMID:17442697 |
| mesenchymal to epithelial transition involved in metanephros morphogenesis | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| mesoderm formation | | IDA | | 2290270 | MGI:MGI:70235|PMID:7799920 | MGI | MGI:MGI:70235 PMID:7799920 |
| mesoderm formation | | IDA | | 2290270 | MGI:MGI:4415813|PMID:18462699 | MGI | MGI:MGI:4415813 PMID:18462699 |
| mesodermal cell differentiation | | IDA | | 2290270 | MGI:MGI:70235|PMID:7799920 | MGI | MGI:MGI:70235 PMID:7799920 |
| mesodermal cell fate determination | | IMP | MGI:MGI:1857137 | 2290270 | MGI:MGI:76261|PMID:7657163 | MGI | MGI:MGI:76261 PMID:7657163 |
| metanephric collecting duct development | | IMP | | 2290270 | MGI:MGI:3710018|PMID:17442697 | UniProtKB | MGI:MGI:3710018 PMID:17442697 |
| metanephros development | | IDA | | 2290270 | MGI:MGI:2655937|PMID:12631064 | MGI | MGI:MGI:2655937 PMID:12631064 |
| metanephros development | | IMP | MGI:MGI:2158495 | 2290270 | MGI:MGI:2655937|PMID:12631064 | MGI | MGI:MGI:2655937 PMID:12631064 |
| monocyte differentiation | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| multicellular organismal development | | IEA | UniProtKB-KW:KW-0217 | 2290270 | MGI:MGI:1354194 | UniProtKB | MGI:MGI:1354194 |
| negative regulation of apoptotic process | | IMP | | 2290270 | MGI:MGI:2655937|PMID:12631064 | UniProtKB | MGI:MGI:2655937 PMID:12631064 |
| negative regulation of apoptotic process | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| negative regulation of branching involved in ureteric bud morphogenesis | | IDA | | 2290270 | MGI:MGI:3525902|PMID:15634693 | UniProtKB | MGI:MGI:3525902 PMID:15634693 |
| negative regulation of branching involved in ureteric bud morphogenesis | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| negative regulation of cell cycle | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| negative regulation of cell death | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| negative regulation of cell proliferation | | IGI | MGI:MGI:104327 | 2290270 | MGI:MGI:3771245|PMID:18028901 | MGI | MGI:MGI:3771245 PMID:18028901 |
| negative regulation of cell proliferation | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:892820|PMID:9187146 | MGI | MGI:MGI:892820 PMID:9187146 |
| negative regulation of cell proliferation involved in heart morphogenesis | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| negative regulation of chondrocyte differentiation | | IDA | | 2290270 | MGI:MGI:3714677|PMID:17481601 | MGI | MGI:MGI:3714677 PMID:17481601 |
| negative regulation of epithelial cell proliferation | | IMP | MGI:MGI:1857137 | 2290270 | MGI:MGI:1934513|PMID:11401393 | MGI | MGI:MGI:1934513 PMID:11401393 |
| negative regulation of gene expression | | IDA | | 2290270 | MGI:MGI:2135612|PMID:11493558 | MGI | MGI:MGI:2135612 PMID:11493558 |
| negative regulation of glomerular mesangial cell proliferation | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| negative regulation of glomerulus development | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| negative regulation of immature T cell proliferation in thymus | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| negative regulation of MAP kinase activity | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| negative regulation of mesenchymal cell proliferation involved in ureter development | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| negative regulation of metanephric comma-shaped body morphogenesis | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| negative regulation of metanephric S-shaped body morphogenesis | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| negative regulation of mitosis | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| negative regulation of myoblast differentiation | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:2154458 | MGI | MGI:MGI:2154458 |
| negative regulation of oligodendrocyte differentiation | | ISO | UniProtKB:Q06826 | 2290270 | MGI:MGI:4417868 | RGD | MGI:MGI:4417868 |
| negative regulation of phosphorylation | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| negative regulation of prostatic bud formation | | IMP | MGI:MGI:1857137 | 2290270 | MGI:MGI:1934513|PMID:11401393 | MGI | MGI:MGI:1934513 PMID:11401393 |
| negative regulation of prostatic bud formation | | IDA | | 2290270 | MGI:MGI:3785350|PMID:18393306 | MGI | MGI:MGI:3785350 PMID:18393306 |
| negative regulation of striated muscle tissue development | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:2154458 | MGI | MGI:MGI:2154458 |
| negative regulation of T cell differentiation in thymus | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| negative regulation of thymocyte apoptotic process | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| negative regulation of transcription from RNA polymerase II promoter | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:892820|PMID:9187146 | MGI | MGI:MGI:892820 PMID:9187146 |
| negative regulation of transcription from RNA polymerase II promoter | | IDA | | 2290270 | MGI:MGI:1205964|PMID:9585504 | MGI | MGI:MGI:1205964 PMID:9585504 |
| negative regulation of transcription, DNA-dependent | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| neural tube closure | | IDA | | 2290270 | MGI:MGI:4429763|PMID:19850029 | MGI | MGI:MGI:4429763 PMID:19850029 |
| neuron fate commitment | | IDA | | 2290270 | MGI:MGI:3761972|PMID:17698011 | MGI | MGI:MGI:3761972 PMID:17698011 |
| neuron fate commitment | | IMP | MGI:MGI:2158495 | 2290270 | MGI:MGI:3761972|PMID:17698011 | MGI | MGI:MGI:3761972 PMID:17698011 |
| odontogenesis | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| odontogenesis of dentin-containing tooth | | IDA | | 2290270 | MGI:MGI:3513220|PMID:15525533 | MGI | MGI:MGI:3513220 PMID:15525533 |
| odontogenesis of dentin-containing tooth | | IDA | | 2290270 | MGI:MGI:3603904|PMID:16179481 | MGI | MGI:MGI:3603904 PMID:16179481 |
| odontogenesis of dentin-containing tooth | | IGI | MGI:MGI:1913292 | 2290270 | MGI:MGI:3603904|PMID:16179481 | MGI | MGI:MGI:3603904 PMID:16179481 |
| organ induction | | IMP | MGI:MGI:1857137 | 2290270 | MGI:MGI:1306869|PMID:9806931 | MGI | MGI:MGI:1306869 PMID:9806931 |
| ossification | | IEA | UniProtKB-KW:KW-0892 | 2290270 | MGI:MGI:1354194 | UniProtKB | MGI:MGI:1354194 |
| osteoblast differentiation | | IDA | | 2290270 | MGI:MGI:3525426|PMID:15381701 | MGI | MGI:MGI:3525426 PMID:15381701 |
| osteoblast differentiation | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| ovarian follicle development | | ISO | UniProtKB:Q06826 | 2290270 | MGI:MGI:4417868 | RGD | MGI:MGI:4417868 |
| pituitary gland development | | IMP | MGI:MGI:1857137 | 2290270 | MGI:MGI:1306869|PMID:9806931 | MGI | MGI:MGI:1306869 PMID:9806931 |
| positive chemotaxis | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| positive regulation of apoptotic process | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:892820|PMID:9187146 | MGI | MGI:MGI:892820 PMID:9187146 |
| positive regulation of apoptotic process | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| positive regulation of BMP signaling pathway | | IDA | | 2290270 | MGI:MGI:4418577|PMID:20059955 | UniProtKB | MGI:MGI:4418577 PMID:20059955 |
| positive regulation of bone mineralization | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:2154458 | MGI | MGI:MGI:2154458 |
| positive regulation of branching involved in lung morphogenesis | | IMP | | 2290270 | MGI:MGI:4456940|PMID:17350185 | UniProtKB | MGI:MGI:4456940 PMID:17350185 |
| positive regulation of branching involved in ureteric bud morphogenesis | | ISO | UniProtKB:Q06826 | 2290270 | MGI:MGI:4417868 | RGD | MGI:MGI:4417868 |
| positive regulation of cardiac muscle fiber development | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| positive regulation of cartilage development | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:63446|PMID:3201241 | MGI | MGI:MGI:63446 PMID:3201241 |
| positive regulation of cell death | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:81070|PMID:8674409 | MGI | MGI:MGI:81070 PMID:8674409 |
| positive regulation of cell differentiation | | IDA | | 2290270 | MGI:MGI:3513220|PMID:15525533 | MGI | MGI:MGI:3513220 PMID:15525533 |
| positive regulation of cell proliferation | | IMP | MGI:MGI:2158495 | 2290270 | MGI:MGI:3820452|PMID:18692041 | MGI | MGI:MGI:3820452 PMID:18692041 |
| positive regulation of cell proliferation | | ISO | UniProtKB:Q06826 | 2290270 | MGI:MGI:4417868 | RGD | MGI:MGI:4417868 |
| positive regulation of collagen biosynthetic process | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| positive regulation of DNA-dependent DNA replication | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| positive regulation of endothelial cell differentiation | | IDA | | 2290270 | MGI:MGI:4830635|PMID:20406889 | DFLAT | MGI:MGI:4830635 PMID:20406889 |
| positive regulation of endothelial cell migration | | TAS | | 2290270 | MGI:MGI:4830635|PMID:20406889 | DFLAT | MGI:MGI:4830635 PMID:20406889 |
| positive regulation of endothelial cell migration | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| positive regulation of endothelial cell proliferation | | IDA | | 2290270 | MGI:MGI:4830635|PMID:20406889 | DFLAT | MGI:MGI:4830635 PMID:20406889 |
| positive regulation of endothelial cell proliferation | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| positive regulation of epithelial cell proliferation | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| positive regulation of ERK1 and ERK2 cascade | | IDA | | 2290270 | MGI:MGI:3820452|PMID:18692041 | MGI | MGI:MGI:3820452 PMID:18692041 |
| positive regulation of gene expression | | IMP | MGI:MGI:1857137 | 2290270 | MGI:MGI:3805418|PMID:18622394 | MGI | MGI:MGI:3805418 PMID:18622394 |
| positive regulation of kidney development | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| positive regulation of neuron differentiation | | IDA | | 2290270 | MGI:MGI:1307014|PMID:9786991 | MGI | MGI:MGI:1307014 PMID:9786991 |
| positive regulation of ossification | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:2154458 | MGI | MGI:MGI:2154458 |
| positive regulation of ossification | | ISO | UniProtKB:Q06826 | 2290270 | MGI:MGI:4417868 | RGD | MGI:MGI:4417868 |
| positive regulation of ossification | | ISO | UniProtKB:Q06826 | 2290270 | MGI:MGI:67505|PMID:7911662 | MGI | MGI:MGI:67505 PMID:7911662 |
| positive regulation of ossification | | IDA | | 2290270 | MGI:MGI:63654|PMID:8358941 | MGI | MGI:MGI:63654 PMID:8358941 |
| positive regulation of osteoblast differentiation | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:2154458 | MGI | MGI:MGI:2154458 |
| positive regulation of osteoblast differentiation | | ISO | UniProtKB:Q06826 | 2290270 | MGI:MGI:4417868 | RGD | MGI:MGI:4417868 |
| positive regulation of pathway-restricted SMAD protein phosphorylation | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| positive regulation of protein phosphorylation | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:2154458 | MGI | MGI:MGI:2154458 |
| positive regulation of protein phosphorylation | | IMP | MGI:MGI:2158495 | 2290270 | MGI:MGI:3820452|PMID:18692041 | MGI | MGI:MGI:3820452 PMID:18692041 |
| positive regulation of SMAD protein import into nucleus | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| positive regulation of smooth muscle cell proliferation | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| positive regulation of transcription from RNA polymerase II promoter | | IDA | | 2290270 | MGI:MGI:1340783|PMID:10391928 | MGI | MGI:MGI:1340783 PMID:10391928 |
| positive regulation of transcription from RNA polymerase II promoter | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| positive regulation of transcription from RNA polymerase II promoter | | IGI | MGI:MGI:97168 | 2290270 | MGI:MGI:1336531|PMID:10340755 | MGI | MGI:MGI:1336531 PMID:10340755 |
| positive regulation of transcription from RNA polymerase II promoter | | IDA | | 2290270 | MGI:MGI:1197794|PMID:9501024 | MGI | MGI:MGI:1197794 PMID:9501024 |
| positive regulation of transcription from RNA polymerase II promoter | | IDA | | 2290270 | MGI:MGI:1203304|PMID:9477322 | MGI | MGI:MGI:1203304 PMID:9477322 |
| positive regulation of transcription from RNA polymerase II promoter | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:892820|PMID:9187146 | MGI | MGI:MGI:892820 PMID:9187146 |
| positive regulation of transcription from RNA polymerase II promoter | | IGI | MGI:MGI:97168 | 2290270 | MGI:MGI:83672|PMID:8898217 | MGI | MGI:MGI:83672 PMID:8898217 |
| positive regulation of transcription from RNA polymerase II promoter | | IDA | | 2290270 | MGI:MGI:80924|PMID:8769660 | MGI | MGI:MGI:80924 PMID:8769660 |
| positive regulation of transcription from RNA polymerase II promoter | | IMP | MGI:MGI:2158495 | 2290270 | MGI:MGI:3820452|PMID:18692041 | MGI | MGI:MGI:3820452 PMID:18692041 |
| positive regulation of transcription from RNA polymerase II promoter | | IDA | | 2290270 | MGI:MGI:3820452|PMID:18692041 | MGI | MGI:MGI:3820452 PMID:18692041 |
| positive regulation of transcription from RNA polymerase II promoter | | IDA | | 2290270 | MGI:MGI:3806378|PMID:18776146 | MGI | MGI:MGI:3806378 PMID:18776146 |
| positive regulation of transcription from RNA polymerase II promoter | | IDA | | 2290270 | MGI:MGI:83672|PMID:8898217 | MGI | MGI:MGI:83672 PMID:8898217 |
| positive regulation of transcription from RNA polymerase II promoter | | IDA | | 2290270 | MGI:MGI:83888|PMID:8104708 | MGI | MGI:MGI:83888 PMID:8104708 |
| positive regulation of transcription from RNA polymerase II promoter | | ISO | UniProtKB:Q06826 | 2290270 | MGI:MGI:67505|PMID:7911662 | MGI | MGI:MGI:67505 PMID:7911662 |
| positive regulation of transcription, DNA-dependent | | TAS | | 2290270 | MGI:MGI:4830635|PMID:20406889 | DFLAT | MGI:MGI:4830635 PMID:20406889 |
| positive regulation of transcription, DNA-dependent | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| positive regulation of vascular endothelial growth factor receptor signaling pathway | | TAS | | 2290270 | MGI:MGI:4830635|PMID:20406889 | DFLAT | MGI:MGI:4830635 PMID:20406889 |
| post-embryonic development | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:81070|PMID:8674409 | MGI | MGI:MGI:81070 PMID:8674409 |
| post-embryonic development | | IMP | MGI:MGI:1857137 | 2290270 | MGI:MGI:1095762|PMID:9268572 | MGI | MGI:MGI:1095762 PMID:9268572 |
| prostate gland morphogenesis | | IMP | MGI:MGI:1857137 | 2290270 | MGI:MGI:1934513|PMID:11401393 | MGI | MGI:MGI:1934513 PMID:11401393 |
| prostate gland morphogenesis | | IMP | MGI:MGI:1857137 | 2290270 | MGI:MGI:1095762|PMID:9268572 | MGI | MGI:MGI:1095762 PMID:9268572 |
| protein localization to nucleus | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| pulmonary artery endothelial tube morphogenesis | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| regulation of branching involved in prostate gland morphogenesis | | IMP | MGI:MGI:2158495 | 2290270 | MGI:MGI:3575593|PMID:15772937 | MGI | MGI:MGI:3575593 PMID:15772937 |
| regulation of cartilage development | | IDA | | 2290270 | MGI:MGI:4830625|PMID:20501701 | MGI | MGI:MGI:4830625 PMID:20501701 |
| regulation of cell differentiation | | IGI | MGI:MGI:95586 | 2290270 | MGI:MGI:3513220|PMID:15525533 | MGI | MGI:MGI:3513220 PMID:15525533 |
| regulation of cell differentiation | | ISO | UniProtKB:Q06826 | 2290270 | MGI:MGI:4417868 | RGD | MGI:MGI:4417868 |
| regulation of endothelial cell proliferation | | TAS | | 2290270 | MGI:MGI:4830635|PMID:20406889 | DFLAT | MGI:MGI:4830635 PMID:20406889 |
| regulation of gene expression | | IMP | | 2290270 | MGI:MGI:2135527|PMID:11436557 | MGI | MGI:MGI:2135527 PMID:11436557 |
| regulation of gene expression | | IDA | | 2290270 | MGI:MGI:1353953|PMID:10704389 | MGI | MGI:MGI:1353953 PMID:10704389 |
| regulation of morphogenesis of a branching structure | | IMP | MGI:MGI:1857137 | 2290270 | MGI:MGI:1934513|PMID:11401393 | MGI | MGI:MGI:1934513 PMID:11401393 |
| regulation of odontogenesis of dentin-containing tooth | | IGI | MGI:MGI:99604|MGI:MGI:88177 | 2290270 | MGI:MGI:894889|PMID:9244299 | MGI | MGI:MGI:894889 PMID:9244299 |
| regulation of pathway-restricted SMAD protein phosphorylation | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| regulation of smooth muscle cell differentiation | | IDA | | 2290270 | MGI:MGI:3766861|PMID:17881493 | MGI | MGI:MGI:3766861 PMID:17881493 |
| regulation of smooth muscle cell differentiation | | IGI | MGI:MGI:1347470 | 2290270 | MGI:MGI:3766861|PMID:17881493 | MGI | MGI:MGI:3766861 PMID:17881493 |
| regulation of smooth muscle cell proliferation | | IDA | | 2290270 | MGI:MGI:3578606|PMID:15800000 | MGI | MGI:MGI:3578606 PMID:15800000 |
| renal system development | | IGI | MGI:MGI:102780 | 2290270 | MGI:MGI:4949995|PMID:21281623 | MGI | MGI:MGI:4949995 PMID:21281623 |
| renal system process | | IMP | MGI:MGI:1857137 | 2290270 | MGI:MGI:1095762|PMID:9268572 | MGI | MGI:MGI:1095762 PMID:9268572 |
| secondary heart field specification | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| skeletal system development | | IDA | | 2290270 | MGI:MGI:2683812|PMID:14654219 | MGI | MGI:MGI:2683812 PMID:14654219 |
| skeletal system development | | IMP | MGI:MGI:3041440|MGI:MGI:2654594 | 2290270 | MGI:MGI:3583479|PMID:15936012 | MGI | MGI:MGI:3583479 PMID:15936012 |
| SMAD protein signal transduction | | IDA | | 2290270 | MGI:MGI:1195384|PMID:9420335 | MGI | MGI:MGI:1195384 PMID:9420335 |
| SMAD protein signal transduction | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| smooth muscle cell differentiation | | IDA | | 2290270 | MGI:MGI:3624584|PMID:16546160 | MGI | MGI:MGI:3624584 PMID:16546160 |
| smooth muscle tissue development | | IMP | | 2290270 | MGI:MGI:2655937|PMID:12631064 | UniProtKB | MGI:MGI:2655937 PMID:12631064 |
| specification of organ position | | IMP | | 2290270 | MGI:MGI:3695659|PMID:17071745 | MGI | MGI:MGI:3695659 PMID:17071745 |
| specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| steroid hormone mediated signaling pathway | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| telencephalon development | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:892820|PMID:9187146 | MGI | MGI:MGI:892820 PMID:9187146 |
| telencephalon regionalization | | IDA | | 2290270 | MGI:MGI:3640853|PMID:16855091 | MGI | MGI:MGI:3640853 PMID:16855091 |
| telencephalon regionalization | | IGI | MGI:MGI:96785 | 2290270 | MGI:MGI:2154554|PMID:11719201 | MGI | MGI:MGI:2154554 PMID:11719201 |
| tendon cell differentiation | | IMP | | 2290270 | MGI:MGI:4418577|PMID:20059955 | UniProtKB | MGI:MGI:4418577 PMID:20059955 |
| tissue development | | IGI | MGI:MGI:2137520 | 2290270 | MGI:MGI:3043486|PMID:14681194 | MGI | MGI:MGI:3043486 PMID:14681194 |
| trachea development | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:81070|PMID:8674409 | MGI | MGI:MGI:81070 PMID:8674409 |
| trachea formation | | IMP | MGI:MGI:3797048 | 2290270 | MGI:MGI:3820452|PMID:18692041 | MGI | MGI:MGI:3820452 PMID:18692041 |
| type B pancreatic cell development | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| ureter epithelial cell differentiation | | IMP | | 2290270 | MGI:MGI:3710018|PMID:17442697 | UniProtKB | MGI:MGI:3710018 PMID:17442697 |
| ureter smooth muscle cell differentiation | | IMP | | 2290270 | MGI:MGI:3710018|PMID:17442697 | UniProtKB | MGI:MGI:3710018 PMID:17442697 |
| ureteric bud development | | IDA | | 2290270 | MGI:MGI:2655937|PMID:12631064 | MGI | MGI:MGI:2655937 PMID:12631064 |
| ureteric bud development | | IMP | MGI:MGI:2158495 | 2290270 | MGI:MGI:2655937|PMID:12631064 | MGI | MGI:MGI:2655937 PMID:12631064 |
| ureteric bud development | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:2154458 | MGI | MGI:MGI:2154458 |
| vasculature development | | IMP | MGI:MGI:2158495 | 2290270 | MGI:MGI:3766861|PMID:17881493 | MGI | MGI:MGI:3766861 PMID:17881493 |
Cellular Component
| cytoplasm | | ISO | UniProtKB:Q06826 | 2290270 | MGI:MGI:4417868 | RGD | MGI:MGI:4417868 |
| extracellular region | | IDA | | 2290270 | MGI:MGI:63654|PMID:8358941 | MGI | MGI:MGI:63654 PMID:8358941 |
| extracellular space | | IDA | | 2290270 | MGI:MGI:3714677|PMID:17481601 | MGI | MGI:MGI:3714677 PMID:17481601 |
| extracellular space | | ISO | UniProtKB:Q06826 | 2290270 | MGI:MGI:4417868 | RGD | MGI:MGI:4417868 |
| membrane-bounded vesicle | | ISO | UniProtKB:Q06826 | 2290270 | MGI:MGI:4417868 | RGD | MGI:MGI:4417868 |
| proteinaceous extracellular matrix | | IEA | UniProtKB-KW:KW-0272 | 2290270 | MGI:MGI:1354194 | UniProtKB | MGI:MGI:1354194 |
Molecular Function
| BMP receptor binding | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:70105|PMID:7811286 | MGI | MGI:MGI:70105 PMID:7811286 |
| chemoattractant activity | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| cytokine activity | | ISO | UniProtKB:P12644 | 2290270 | MGI:MGI:2154458 | MGI | MGI:MGI:2154458 |
| growth factor activity | | ISO | UniProtKB:Q06826 | 2290270 | MGI:MGI:4417868 | RGD | MGI:MGI:4417868 |
| heparin binding | | IDA | | 2290270 | MGI:MGI:3525426|PMID:15381701 | MGI | MGI:MGI:3525426 PMID:15381701 |
| protein binding | | IPI | UniProtKB:Q8CF09 | 2290270 | MGI:MGI:2681048|PMID:14623234 | MGI | MGI:MGI:2681048 PMID:14623234 |
| protein binding | | IPI | UniProtKB:Q9D236 | 2290270 | MGI:MGI:3046453|PMID:15206957 | UniProtKB | MGI:MGI:3046453 PMID:15206957 |
| protein binding | | IPI | UniProtKB:Q7TQ32 | 2290270 | MGI:MGI:3625588|PMID:16604073 | MGI | MGI:MGI:3625588 PMID:16604073 |
| protein binding | | IPI | UniProtKB:Q9ERN7 | 2290270 | MGI:MGI:3525426|PMID:15381701 | MGI | MGI:MGI:3525426 PMID:15381701 |
| protein binding | | IPI | UniProtKB:Q6PCX7 | 2290270 | MGI:MGI:3590430|PMID:15975920 | MGI | MGI:MGI:3590430 PMID:15975920 |
| protein binding | | IPI | UniProtKB:Q8CJ69 | 2290270 | MGI:MGI:2670247|PMID:12897139 | MGI | MGI:MGI:2670247 PMID:12897139 |
| protein binding | | IPI | UniProtKB:Q9R118 | 2290270 | MGI:MGI:3034116|PMID:14973287 | MGI | MGI:MGI:3034116 PMID:14973287 |
| protein binding | | IPI | UniProtKB:Q8VEA6 | 2290270 | MGI:MGI:2683044|PMID:14660436 | MGI | MGI:MGI:2683044 PMID:14660436 |
| protein homodimerization activity | | ISO | UniProtKB:Q06826 | 2290270 | MGI:MGI:4417868 | RGD | MGI:MGI:4417868 |