Gene: Lrp6 (low density lipoprotein receptor-related protein 6)  Mus musculus

Symbol: Lrp6
Name: low density lipoprotein receptor-related protein 6
Description: ENCODES a protein that exhibits apolipoprotein binding; toxin transporter activity; Wnt-protein binding; INVOLVED IN anterior/posterior pattern specification; axis elongation; axis elongation involved in somitogenesis; PARTICIPATES IN canonical Wnt signaling pathway; Wnt signaling pathway; ASSOCIATED WITH abnormal adaptive thermogenesis; abnormal amnion morphology; abnormal anterior-posterior polarity of the somites; ASSOCIATED WITH Liver Cirrhosis, Experimental; Coronary Artery Disease, Autosomal Dominant 2 (ortholog); Metabolic Syndrome X (ortholog); FOUND IN early endosome; membrane; plasma membrane; INTERACTS WITH all-trans-retinoic acid; benzo[a]pyrene; cadmium dichloride
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C030016K15Rik; Cd; crooked; Gw; low density lipoprotein receptor-related protein 6; low density lipoprotein-related protein 6; low density lipoprotein-related protein 6; low-density lipoprotein receptor-related protein 6; LRP-6; OTTMUSP00000023469
Orthologs: Homo sapiens : LRP6 (low density lipoprotein receptor-related protein 6)  HGNC
Rattus norvegicus : Lrp6 (low density lipoprotein receptor-related protein 6)
Latest Assembly: Mouse Genome Assembly Build 37
Position:
MapChrPositionStrandSource
Mouse Genome Assembly GRCm386134,446,476 - 134,566,913-NCBI
Mouse cM Map665.37 NCBI
Mouse Celera Assembly6137,380,826 - 137,512,292-NCBI
Mouse Genome Assembly Build 376134,400,434 - 134,516,931-NCBI
Mouse Genome Assembly Build 36.16134,400,227 - 134,516,800-NCBI
Mouse Cytogenetic Map6 G1 NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Mouse Genome Assembly Build 37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Lrp6
Entrez Gene
Ensembl Gene
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MGI Report
NCBI Map Viewer
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RGD Object Information
RGD ID: 1312374
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2013-05-14
Status: ACTIVE