Wnt11 (wingless-type MMTV integration site family, member 11) - Rat Genome Database

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Gene: Wnt11 (wingless-type MMTV integration site family, member 11) Mus musculus
Analyze
Symbol: Wnt11
Name: wingless-type MMTV integration site family, member 11
RGD ID: 1551956
MGI Page MGI
Description: Predicted to enable enzyme activator activity and signaling receptor binding activity. Involved in heart development. Acts upstream of or within several processes, including Wnt signaling pathway; circulatory system development; and negative regulation of cell population proliferation. Located in extracellular matrix and extracellular region. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and limb. Human ortholog(s) of this gene implicated in oral squamous cell carcinoma. Orthologous to human WNT11 (Wnt family member 11).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: protein Wnt-11; wingless-related MMTV integration site 11
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39798,484,293 - 98,503,954 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl798,484,319 - 98,504,402 (+)EnsemblGRCm39 Ensembl
GRCm38798,835,084 - 98,854,747 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl798,835,112 - 98,855,195 (+)EnsemblGRCm38mm10GRCm38
MGSCv377105,987,355 - 106,003,257 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36798,714,037 - 98,728,940 (+)NCBIMGSCv36mm8
Celera799,160,445 - 99,176,286 (+)NCBICelera
Cytogenetic Map7E1NCBI
cM Map753.9NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroperoxycyclophosphamide  (EXP)
6-propyl-2-thiouracil  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP)
ammonium chloride  (ISO)
amosite asbestos  (ISO)
amphetamine  (ISO)
antirheumatic drug  (ISO)
Aroclor 1254  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
cadmium sulfate  (EXP)
cannabidiol  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
deguelin  (ISO)
dexamethasone  (EXP,ISO)
dibutyl phthalate  (ISO)
diethylstilbestrol  (EXP)
dimethyl sulfoxide  (ISO)
disodium selenite  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
fenfluramine  (ISO)
fluvastatin  (ISO)
folic acid  (EXP)
furan  (ISO)
gentamycin  (ISO)
glycerol 2-phosphate  (EXP)
indometacin  (ISO)
L-ascorbic acid  (EXP)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
manganese(II) chloride  (ISO)
nickel atom  (ISO)
nitrofen  (ISO)
paracetamol  (EXP,ISO)
pentanal  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (ISO)
phenobarbital  (ISO)
progesterone  (EXP,ISO)
propanal  (ISO)
quercetin  (ISO)
raloxifene  (ISO)
retinyl acetate  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
sotorasib  (ISO)
sunitinib  (ISO)
thioacetamide  (ISO)
trametinib  (ISO)
trimellitic anhydride  (EXP)
triptonide  (EXP)
urethane  (ISO)
valproic acid  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adrenal gland development  (ISO)
animal organ morphogenesis  (TAS)
apoptotic process  (IMP)
artery morphogenesis  (IMP)
atrial septum development  (IGI)
bicellular tight junction assembly  (IMP)
bone mineralization  (IGI)
canonical Wnt signaling pathway  (IBA,IDA)
cell differentiation  (ISO)
cell fate commitment  (IBA)
cell-cell signaling  (TAS)
cellular response to mechanical stimulus  (IDA)
cloacal septation  (ISO)
convergent extension involved in axis elongation  (IGI)
embryonic skeletal system development  (ISO)
epithelial cell apoptotic process  (IMP)
epithelial to mesenchymal transition  (IGI)
kidney development  (IDA)
lung-associated mesenchyme development  (ISO)
maintenance of epithelial cell apical/basal polarity  (IGI)
mesenchymal cell proliferation  (IMP)
mesonephric duct development  (ISO)
negative regulation of canonical Wnt signaling pathway  (IDA,ISO)
negative regulation of cell growth  (ISO)
negative regulation of cell migration  (ISO)
negative regulation of DNA-templated transcription  (ISO)
negative regulation of fibroblast growth factor production  (IMP)
negative regulation of mesenchymal cell proliferation  (IMP)
negative regulation of stem cell proliferation  (IMP)
neuroendocrine cell differentiation  (ISO)
neuron differentiation  (IBA)
non-canonical Wnt signaling pathway  (IMP)
notochord morphogenesis  (IGI)
osteoblast differentiation  (IGI)
outflow tract morphogenesis  (IMP)
paraxial mesoderm formation  (IGI)
planar cell polarity pathway involved in axis elongation  (IGI)
planar cell polarity pathway involved in gastrula mediolateral intercalation  (IGI)
positive regulation of apoptotic process  (IMP)
positive regulation of DNA-templated transcription  (ISO)
positive regulation of epithelial cell apoptotic process  (IMP)
positive regulation of protein kinase C signaling  (ISO)
positive regulation of stress fiber assembly  (ISO)
positive regulation of transforming growth factor beta2 production  (IMP)
primary heart field specification  (IGI)
protein localization to cell surface  (ISO)
response to nutrient levels  (ISO)
roof of mouth development  (IMP)
secondary heart field specification  (IGI)
secondary palate development  (ISO)
signal transduction  (ISO,TAS)
somite development  (IGI)
stem cell proliferation  (IMP)
ureteric bud morphogenesis  (ISO)
ventricular septum development  (IGI)
ventricular septum morphogenesis  (IMP)
Wnt signaling pathway  (IEA)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Insights from studies with oral cleft genes suggest associations between WNT-pathway genes and risk of oral cancer. Andrade Filho PA, etal., J Dent Res. 2011 Jun;90(6):740-6. doi: 10.1177/0022034511401622. Epub 2011 Mar 10.
2. Molecular cloning and characterization of human WNT11. Kirikoshi H, etal., Int J Mol Med. 2001 Dec;8(6):651-6.
3. Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development. Majumdar A, etal., Development 2003 Jul;130(14):3175-85.
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. MGD IEA MGD IEA
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. Wnt11 signaling promotes proliferation, transformation, and migration of IEC6 intestinal epithelial cells. Ouko L, etal., J Biol Chem 2004 Jun 18;279(25):26707-15. Epub 2004 Apr 14.
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. Mouse MP Annotation Import Pipeline RGD automated import pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Wnt signaling in the ovary: identification and compartmentalized expression of wnt-2, wnt-2b, and frizzled-4 mRNAs. Ricken A, etal., Endocrinology 2002 Jul;143(7):2741-9.
13. The Wnt Homepage Roel Nusse - Howard Hughes Medical Institute and the Department of Developmental Biology at Stanford University, California, USA
14. Alternative wnt signaling is initiated by distinct receptors. van Amerongen R, etal., Sci Signal. 2008 Sep 2;1(35):re9.
15. Analysis of Wnt gene expression in prostate cancer: mutual inhibition by WNT11 and the androgen receptor. Zhu H, etal., Cancer Res. 2004 Nov 1;64(21):7918-26.
Additional References at PubMed
PMID:7547479   PMID:7896292   PMID:8570653   PMID:8575777   PMID:8636124   PMID:8700530   PMID:8747928   PMID:8951078   PMID:9152004   PMID:9637690   PMID:9757009   PMID:9811581  
PMID:9889131   PMID:10021334   PMID:10349636   PMID:10352232   PMID:10441734   PMID:10501973   PMID:10585256   PMID:10749566   PMID:10862149   PMID:11042159   PMID:11076861   PMID:11133159  
PMID:11180950   PMID:11217851   PMID:11429295   PMID:11455436   PMID:11493536   PMID:11520664   PMID:11562352   PMID:11914369   PMID:12412008   PMID:12477932   PMID:12591246   PMID:12702652  
PMID:12815618   PMID:14667410   PMID:14681479   PMID:15044261   PMID:15067007   PMID:15201220   PMID:15226823   PMID:15342465   PMID:15363409   PMID:15525990   PMID:15541384   PMID:15543138  
PMID:15637299   PMID:15691764   PMID:15797385   PMID:15843407   PMID:15880404   PMID:15901664   PMID:15930111   PMID:16054034   PMID:16141072   PMID:16141073   PMID:16291790   PMID:16319112  
PMID:16378759   PMID:16426441   PMID:16439479   PMID:16678101   PMID:16687132   PMID:16720880   PMID:16839542   PMID:17036046   PMID:17050624   PMID:17055474   PMID:17119020   PMID:17151017  
PMID:17154359   PMID:17314325   PMID:17350578   PMID:17425782   PMID:17452023   PMID:17519333   PMID:17522159   PMID:17767158   PMID:17804636   PMID:17826763   PMID:17943183   PMID:17950287  
PMID:18000065   PMID:18155657   PMID:18159948   PMID:18177851   PMID:18191119   PMID:18287559   PMID:18351662   PMID:18351675   PMID:18358465   PMID:18364260   PMID:18367557   PMID:18604206  
PMID:18606138   PMID:18635608   PMID:18650792   PMID:18723448   PMID:18832392   PMID:18955134   PMID:18991257   PMID:19004760   PMID:19014928   PMID:19060336   PMID:19164599   PMID:19165927  
PMID:19185060   PMID:19213727   PMID:19282366   PMID:19369396   PMID:19515997   PMID:19562671   PMID:19619491   PMID:19622544   PMID:19715689   PMID:19741018   PMID:19805103   PMID:19806668  
PMID:19809516   PMID:19898483   PMID:20040500   PMID:20084103   PMID:20439720   PMID:20454682   PMID:20843830   PMID:20890044   PMID:20940229   PMID:20944551   PMID:20962251   PMID:21035938  
PMID:21041481   PMID:21060807   PMID:21145505   PMID:21212101   PMID:21248711   PMID:21267068   PMID:21281623   PMID:21289216   PMID:21303848   PMID:21339645   PMID:21343368   PMID:21420949  
PMID:21463175   PMID:21523854   PMID:21531785   PMID:21552539   PMID:21613322   PMID:21623369   PMID:21664901   PMID:21677750   PMID:21873635   PMID:21903675   PMID:21903761   PMID:21936019  
PMID:21949185   PMID:21963425   PMID:22015719   PMID:22024319   PMID:22114682   PMID:22190459   PMID:22410172   PMID:22434869   PMID:22493062   PMID:22510988   PMID:22511595   PMID:22556418  
PMID:22569553   PMID:22627288   PMID:22677559   PMID:22715413   PMID:22829700   PMID:22912798   PMID:22956684   PMID:23034629   PMID:23095888   PMID:23190887   PMID:23207593   PMID:23274346  
PMID:23324743   PMID:23376422   PMID:23546880   PMID:23613470   PMID:23616926   PMID:23637775   PMID:23684768   PMID:23704941   PMID:23762375   PMID:23791818   PMID:23884445   PMID:24151333  
PMID:24194600   PMID:24394376   PMID:24418259   PMID:24440154   PMID:24550112   PMID:24586192   PMID:24603431   PMID:24637293   PMID:24661562   PMID:24671096   PMID:24821700   PMID:24852369  
PMID:24952961   PMID:24996922   PMID:25053429   PMID:25312921   PMID:25448697   PMID:25482987   PMID:25651362   PMID:25687138   PMID:25713299   PMID:25727890   PMID:25758227   PMID:25803581  
PMID:25804736   PMID:25813538   PMID:25959411   PMID:26047795   PMID:26093309   PMID:26235626   PMID:26238476   PMID:26295701   PMID:26450967   PMID:26512061   PMID:26604140   PMID:26667040  
PMID:26685160   PMID:26845523   PMID:26859490   PMID:26883626   PMID:27026076   PMID:27151977   PMID:27362799   PMID:27480037   PMID:27582005   PMID:27626380   PMID:28069946   PMID:28077488  
PMID:28292423   PMID:28348167   PMID:28478097   PMID:28538179   PMID:28669819   PMID:28705898   PMID:28813421   PMID:28834739   PMID:28993400   PMID:29016838   PMID:29031500   PMID:29056552  
PMID:29129523   PMID:29158444   PMID:29240767   PMID:29357412   PMID:29432158   PMID:29891676   PMID:29945868   PMID:30347193   PMID:30377232   PMID:30516471   PMID:30651543   PMID:30940800  
PMID:31024170   PMID:31042081   PMID:31226309   PMID:31246175   PMID:31338035   PMID:32325033   PMID:32464196   PMID:32511952   PMID:32715478   PMID:32901292   PMID:32907846   PMID:33082334  
PMID:33141892   PMID:33171097   PMID:33188033   PMID:33315499   PMID:34032268   PMID:34861058   PMID:34861428   PMID:35831952   PMID:36098469   PMID:36305473   PMID:36435829   PMID:36623578  
PMID:36649430   PMID:37852253   PMID:37982452  


Genomics

Comparative Map Data
Wnt11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39798,484,293 - 98,503,954 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl798,484,319 - 98,504,402 (+)EnsemblGRCm39 Ensembl
GRCm38798,835,084 - 98,854,747 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl798,835,112 - 98,855,195 (+)EnsemblGRCm38mm10GRCm38
MGSCv377105,987,355 - 106,003,257 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36798,714,037 - 98,728,940 (+)NCBIMGSCv36mm8
Celera799,160,445 - 99,176,286 (+)NCBICelera
Cytogenetic Map7E1NCBI
cM Map753.9NCBI
WNT11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381176,186,325 - 76,210,761 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1176,186,325 - 76,210,736 (-)EnsemblGRCh38hg38GRCh38
GRCh371175,897,369 - 75,917,546 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361175,575,018 - 75,595,222 (-)NCBINCBI36Build 36hg18NCBI36
Build 341175,575,017 - 75,595,222NCBI
Celera1173,205,187 - 73,225,391 (-)NCBICelera
Cytogenetic Map11q13.5NCBI
HuRef1172,194,546 - 72,214,753 (-)NCBIHuRef
CHM1_11175,780,888 - 75,801,091 (-)NCBICHM1_1
T2T-CHM13v2.01176,116,041 - 76,140,519 (-)NCBIT2T-CHM13v2.0
Wnt11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81162,545,660 - 162,565,456 (+)NCBIGRCr8
mRatBN7.21153,134,503 - 153,154,294 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1153,138,197 - 153,154,294 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1161,133,836 - 161,149,936 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01168,314,007 - 168,330,107 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01161,187,522 - 161,203,622 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01163,794,136 - 163,813,756 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1163,797,660 - 163,813,756 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01169,997,286 - 170,016,829 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41156,125,969 - 156,142,065 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11156,213,816 - 156,216,652 (+)NCBI
Celera1151,224,671 - 151,240,729 (+)NCBICelera
Cytogenetic Map1q32NCBI
Wnt11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541415,674,940 - 15,694,883 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541415,674,478 - 15,694,758 (+)NCBIChiLan1.0ChiLan1.0
WNT11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2977,110,987 - 77,161,434 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11178,156,064 - 78,180,195 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01171,239,781 - 71,263,915 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11174,540,025 - 74,560,024 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1174,540,169 - 74,560,024 (-)Ensemblpanpan1.1panPan2
WNT11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12122,442,496 - 22,463,040 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2122,446,051 - 22,463,173 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2122,210,200 - 22,227,251 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02122,648,822 - 22,665,821 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2122,648,814 - 22,665,904 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12122,423,226 - 22,440,217 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02122,642,741 - 22,659,738 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02122,561,731 - 22,578,745 (+)NCBIUU_Cfam_GSD_1.0
Wnt11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494763,309,313 - 63,329,371 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364984,908,978 - 4,927,165 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364984,909,041 - 4,927,482 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WNT11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl910,413,263 - 10,435,100 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1910,413,182 - 10,435,158 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2911,487,189 - 11,509,672 (+)NCBISscrofa10.2Sscrofa10.2susScr3
WNT11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1167,393,975 - 67,427,247 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl167,399,074 - 67,418,509 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604358,377,747 - 58,402,147 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wnt11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624817932,970 - 952,326 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624817931,686 - 952,474 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Wnt11
615 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1953
Count of miRNA genes:624
Interacting mature miRNAs:799
Transcripts:ENSMUST00000067495, ENSMUST00000163913, ENSMUST00000165122, ENSMUST00000165240, ENSMUST00000167303
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730199425108999207Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736280015116416877Mouse
1300791Abbp3_mA/J and C57BL/6 blood pressure 3 (mouse)Not determined739673887103510010Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745161966118693530Mouse
13208555Lgth10_mbody length 10 (mouse)751649748125599172Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753249748143153737Mouse
25823170Hrsq7_mhost response to SARS QTL 7, log titer (mouse)754819589116822815Mouse
27226778Femd11_mfemur midshaft diameter 11, 16 week (mouse)756949748134001729Mouse
26884408Bzwq13_mbi-zygomatic width QTL 13, 16 week (mouse)761749748121399223Mouse
27095916Scvln15_msacral vertebrae length 2, 16 week (mouse)761749748123699223Mouse
25314305Vmm6_mvariable multisystem mineralization 6, eye (mouse)761849748102749207Mouse
26884440Sklq4_mskull length QTL 4, 5 week (mouse)765249748126499172Mouse
11553865Stmm1c_mskin tumor modifier of MSM 1c (mouse)76578898699788986Mouse
11553866Stmm1d_mskin tumor modifier of MSM 1d (mouse)76578898699788986Mouse
1301826Pgia3_mproteoglycan induced arthritis 3 (mouse)Not determined767290094101290240Mouse
1301784Ses2_msalmonella enteritidis susceptibility 2 (mouse)Not determined767290094101290240Mouse
1300620Pgia21_mproteoglycan induced arthritis 21 (mouse)Not determined767290094101290240Mouse
26884418Bzwq7_mbi-zygomatic width QTL 7, 10 week (mouse)767849748105449207Mouse
27226715Metcl3_mmetatarsal-calcaneal length 3, 5 week (mouse)767849748119499223Mouse
26884444Sklq8_mskull length QTL 8, 10 week (mouse)767849748124199223Mouse
26884451Sklq14_mskull length QTL 14, 16 week (mouse)767849748124999172Mouse
1300654Bomd1_mbone mineral density 1 (mouse)Not determined768365595102365702Mouse
27095907Scvln4_msacral vertebrae length 2, 5 week (mouse)769949748120499223Mouse
1301155Bpq7_mblood pressure QTL 7 (mouse)Not determined770143137104143379Mouse
10043973Obq29_mobesity QTL 29 (mouse)Not determined772263372106263372Mouse
27095910Pglq13_mpelvic girdle length QTL 13, 16 week (mouse)773049748125699172Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773149748143153737Mouse
11553869Stmm2b_mskin tumor modifier of MSM 2a (mouse)773725965107725965Mouse
27226745Metcl9_mmetatarsal-calcaneal length 9, 10 week (mouse)774849748122199223Mouse
27226781Tibl3_mtibia length 3, 5 week (mouse)774849748122199223Mouse
1301566Adip3_madiposity 3 (mouse)Not determined775394215109394346Mouse
14746989Manh62_mmandible shape 62 (mouse)775742528109742528Mouse
26884398Humsd6_mhumerus midshaft diameter 6, 16 week (mouse)778649748136901729Mouse
10412110Cctq1_mcentral corneal thickness QTL 1 (mouse)Not determined780551681114551791Mouse
4142500Morq1_mmodifier of Rs1 QTL 1 (mouse)Not determined80551681114551791Mouse
27095930Ulnl10_mulna length 10, 16 week (mouse)780849748126699172Mouse
27095923Pglq3_mpelvic girdle length QTL 3, 5 week (mouse)781249748124199223Mouse
27095903Scvln10_msacral vertebrae length 2, 10 week (mouse)781449748126499172Mouse
27226765Tibl18_mtibia length 18, 16 week (mouse)781849748126499172Mouse
27226763Feml20_mfemur length 20, 16 week (mouse)785049208124199223Mouse
1301997Cia7_mcollagen induced arthritis QTL 7 (mouse)Not determined785365595112533819Mouse
27226792Feml7_mfemur length 7, 5 week (mouse)78614920898949207Mouse
1301647Elpt_melevated leptin (mouse)Not determined786500186120500329Mouse
1301188Heal6_mwound healing/regeneration 6 (mouse)Not determined787043932121044066Mouse
1302062Stheal6_msoft tissue heal 6 (mouse)Not determined787043932121044066Mouse
13463473Hbbcq4_mhemoglobin concentration QTL 4 (mouse)787043932121044066Mouse
1301781Capsq3_mcapsaicin sensitivity related QTL 3 (mouse)Not determined787143137119485380Mouse
27226769Tibl12_mtibia length 12, 10 week (mouse)787249208126499172Mouse
27226790Feml15_mfemur length 15, 10 week (mouse)787249208126499172Mouse
27095929Pglq8_mpelvic girdle length QTL 8, 10 week (mouse)787849208108099207Mouse
1357664Nba3_mNew Zealand Black autoimmunity 3 (mouse)Not determined791482996125483156Mouse
1301937Skull10_mskull morphology 10 (mouse)Not determined791482996125483156Mouse
13464255Ifvrq2_minfluenza virus resistance QTL 2 (mouse)792500698106455693Mouse
1300528Ssial3_msusceptibility to sialadenitis 3 (mouse)Not determined793391848127392041Mouse
1301478Eae26_msusceptibility to experimental allergic encephalomyelitis 26 (mouse)Not determined798164922132165010Mouse
13524850Asrq7_macoustic startle response 7 (mouse)798394974132394974Mouse

Markers in Region
Wnt11  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv377106,001,630 - 106,002,091UniSTSGRCm37
MGSCv377106,001,790 - 106,001,936UniSTSGRCm37
MGSCv377105,995,026 - 105,995,742UniSTSGRCm37
MGSCv377105,994,915 - 105,995,119UniSTSGRCm37
MGSCv377106,001,935 - 106,002,130UniSTSGRCm37
Celera799,168,061 - 99,168,777UniSTS
Celera799,174,659 - 99,175,120UniSTS
Celera799,167,950 - 99,168,154UniSTS
Celera799,174,819 - 99,174,965UniSTS
Celera799,174,964 - 99,175,159UniSTS
Cytogenetic Map7E2UniSTS
cM Map748.0UniSTS
cM Map748.0UniSTS
X70800  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38798,853,416 - 98,853,509UniSTSGRCm38
MGSCv377106,001,926 - 106,002,019UniSTSGRCm37
Celera799,174,955 - 99,175,048UniSTS
Cytogenetic Map7E2UniSTS
cM Map748.0UniSTS
Whitehead/MRC_RH7999.67UniSTS
Wnt11  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38798,853,280 - 98,853,426UniSTSGRCm38
MGSCv377106,001,790 - 106,001,936UniSTSGRCm37
Celera799,174,819 - 99,174,965UniSTS
Cytogenetic Map7E2UniSTS
Wnt11  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38798,853,120 - 98,853,581UniSTSGRCm38
MGSCv377106,001,630 - 106,002,091UniSTSGRCm37
Celera799,174,659 - 99,175,120UniSTS
Cytogenetic Map7E2UniSTS
Wnt11  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38798,846,516 - 98,847,232UniSTSGRCm38
MGSCv377105,995,026 - 105,995,742UniSTSGRCm37
Celera799,168,061 - 99,168,777UniSTS
Cytogenetic Map7E2UniSTS
Wnt11  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7E2UniSTS
Wnt11  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38798,846,405 - 98,846,609UniSTSGRCm38
MGSCv377105,994,915 - 105,995,119UniSTSGRCm37
Celera799,167,950 - 99,168,154UniSTS
Cytogenetic Map7E2UniSTS
Wnt11  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38798,853,425 - 98,853,620UniSTSGRCm38
MGSCv377106,001,935 - 106,002,130UniSTSGRCm37
Celera799,174,964 - 99,175,159UniSTS
Cytogenetic Map7E2UniSTS
cM Map748.0UniSTS
Wnt11  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7E2UniSTS
Wnt11  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7E2UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001285792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001285794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001285795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006507586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006507587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011241733 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC110039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK031573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK077828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK138967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC125482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC125484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC144947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CQ970176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X70800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000067495   ⟹   ENSMUSP00000064333
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl798,484,338 - 98,504,402 (+)Ensembl
GRCm38.p6 Ensembl798,835,131 - 98,855,195 (+)Ensembl
RefSeq Acc Id: ENSMUST00000163913   ⟹   ENSMUSP00000126428
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl798,484,319 - 98,503,018 (+)Ensembl
GRCm38.p6 Ensembl798,835,112 - 98,853,811 (+)Ensembl
RefSeq Acc Id: ENSMUST00000165122   ⟹   ENSMUSP00000125789
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl798,484,319 - 98,495,794 (+)Ensembl
GRCm38.p6 Ensembl798,835,112 - 98,846,587 (+)Ensembl
RefSeq Acc Id: ENSMUST00000165240   ⟹   ENSMUSP00000131770
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl798,488,105 - 98,502,778 (+)Ensembl
GRCm38.p6 Ensembl798,838,898 - 98,853,571 (+)Ensembl
RefSeq Acc Id: ENSMUST00000167303   ⟹   ENSMUSP00000132166
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl798,488,052 - 98,502,958 (+)Ensembl
GRCm38.p6 Ensembl798,838,845 - 98,853,751 (+)Ensembl
RefSeq Acc Id: ENSMUST00000208062
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl798,497,013 - 98,499,674 (+)Ensembl
GRCm38.p6 Ensembl798,847,806 - 98,850,467 (+)Ensembl
RefSeq Acc Id: NM_001285792   ⟹   NP_001272721
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39798,484,319 - 98,503,954 (+)NCBI
GRCm38798,835,112 - 98,854,747 (+)NCBI
Celera799,156,719 - 99,176,286 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001285794   ⟹   NP_001272723
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39798,484,319 - 98,503,954 (+)NCBI
GRCm38798,835,112 - 98,854,747 (+)NCBI
Celera799,156,719 - 99,176,286 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001285795   ⟹   NP_001272724
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39798,488,052 - 98,503,954 (+)NCBI
GRCm38798,838,845 - 98,854,747 (+)NCBI
Celera799,156,719 - 99,176,286 (+)NCBI
Sequence:
RefSeq Acc Id: NM_009519   ⟹   NP_033545
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39798,488,052 - 98,503,954 (+)NCBI
GRCm38798,838,845 - 98,854,747 (+)NCBI
MGSCv377105,987,355 - 106,003,257 (+)RGD
Celera799,156,719 - 99,176,286 (+)NCBI
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006507586   ⟹   XP_006507649
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39798,484,294 - 98,503,022 (+)NCBI
GRCm38798,835,086 - 98,854,743 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006507587   ⟹   XP_006507650
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39798,484,293 - 98,503,022 (+)NCBI
GRCm38798,835,084 - 98,854,743 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011241733   ⟹   XP_011240035
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39798,488,311 - 98,503,022 (+)NCBI
GRCm38798,839,104 - 98,853,762 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_033545   ⟸   NM_009519
- Peptide Label: isoform a precursor
- UniProtKB: P48615 (UniProtKB/Swiss-Prot),   Q059Y4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001272721   ⟸   NM_001285792
- Peptide Label: isoform a precursor
- UniProtKB: P48615 (UniProtKB/Swiss-Prot),   Q059Y4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001272723   ⟸   NM_001285794
- Peptide Label: isoform b
- UniProtKB: Q3UTY8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001272724   ⟸   NM_001285795
- Peptide Label: isoform c
- UniProtKB: Q059Y4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006507650   ⟸   XM_006507587
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006507649   ⟸   XM_006507586
- Peptide Label: isoform X1
- UniProtKB: P48615 (UniProtKB/Swiss-Prot),   Q059Y4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011240035   ⟸   XM_011241733
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSMUSP00000126428   ⟸   ENSMUST00000163913
RefSeq Acc Id: ENSMUSP00000125789   ⟸   ENSMUST00000165122
RefSeq Acc Id: ENSMUSP00000064333   ⟸   ENSMUST00000067495
RefSeq Acc Id: ENSMUSP00000131770   ⟸   ENSMUST00000165240
RefSeq Acc Id: ENSMUSP00000132166   ⟸   ENSMUST00000167303

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P48615-F1-model_v2 AlphaFold P48615 1-354 view protein structure

Promoters
RGD ID:8664857
Promoter ID:EPDNEW_M10459
Type:multiple initiation site
Name:Wnt11_1
Description:Mus musculus wingless-type MMTV integration site family, member11 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38798,835,112 - 98,835,172EPDNEW
RGD ID:6842343
Promoter ID:MM_KWN:51649
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Lung
Transcripts:UC009IKV.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv367105,983,499 - 105,983,999 (+)MPROMDB
RGD ID:6842344
Promoter ID:MM_KWN:51650
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:UC009IKW.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv367105,984,396 - 105,984,896 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:101948 AgrOrtholog
Ensembl Genes ENSMUSG00000015957 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000067495 ENTREZGENE
  ENSMUST00000067495.9 UniProtKB/Swiss-Prot
  ENSMUST00000163913.8 UniProtKB/TrEMBL
  ENSMUST00000165122.8 UniProtKB/TrEMBL
  ENSMUST00000165240.2 UniProtKB/TrEMBL
  ENSMUST00000167303 ENTREZGENE
  ENSMUST00000167303.8 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.2460.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Wnt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Wnt_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Wnt_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:22411 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:101948 ENTREZGENE
NCBI Gene 22411 ENTREZGENE
PANTHER PTHR12027 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12027:SF7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam wnt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Wnt11 PhenoGen
PRINTS WNTPROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE WNT1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART WNT1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt E9PVI8_MOUSE UniProtKB/TrEMBL
  E9PYZ1_MOUSE UniProtKB/TrEMBL
  E9Q692_MOUSE UniProtKB/TrEMBL
  P48615 ENTREZGENE
  Q059Y4 ENTREZGENE, UniProtKB/TrEMBL
  Q3UTY8 ENTREZGENE, UniProtKB/TrEMBL
  WNT11_MOUSE UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-07-01 Wnt11  wingless-type MMTV integration site family, member 11    wingless-related MMTV integration site 11  Symbol and/or name change 5135510 APPROVED