Pias2 (protein inhibitor of activated STAT, 2)

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Gene: Pias2 (protein inhibitor of activated STAT, 2) Rattus norvegicus

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Symbol:

Pias2

Name:

protein inhibitor of activated STAT, 2

RGD ID:

71056

Description:

Enables nuclear receptor binding activity and protein domain specific binding activity. Involved in several processes, including androgen receptor signaling pathway; positive regulation of dendrite morphogenesis; and response to testosterone. Acts upstream of or within regulation of androgen receptor signaling pathway. Located in nucleus. Orthologous to human PIAS2 (protein inhibitor of activated STAT 2); PARTICIPATES IN androgen signaling pathway; Jak-Stat signaling pathway; hepatitis C pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; bisphenol A; finasteride.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

androgen receptor-interacting protein 3; ARIP3; DAB2-interacting protein; DIP; E3 SUMO-protein ligase PIAS2; E3 SUMO-protein transferase PIAS2; Miz1; Msx-interacting-zinc finger; PiasX; PIASxα; PIASxβ; protein inhibitor of activated STAT 2; protein inhibitor of activated STAT x

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PIAS2 (protein inhibitor of activated STAT 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Pias2 (protein inhibitor of activated STAT 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Pias2 (protein inhibitor of activated STAT 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PIAS2 (protein inhibitor of activated STAT 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PIAS2 (protein inhibitor of activated STAT 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Pias2 (protein inhibitor of activated STAT 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PIAS2 (protein inhibitor of activated STAT 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PIAS2 (protein inhibitor of activated STAT 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Pias2 (protein inhibitor of activated STAT 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Pias2 (protein inhibitor of activated STAT 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	PIAS2 (protein inhibitor of activated STAT 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	pias2 (protein inhibitor of activated STAT, 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	NFI1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Su(var)2-10	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	gei-17	Alliance	DIOPT (Hieranoid\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	SIZ1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	pias2	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	72,883,008 - 72,989,486 (+)	NCBI		GRCr8
mRatBN7.2	18	70,608,034 - 70,714,295 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	70,607,665 - 70,710,033 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	72,729,105 - 72,813,704 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	73,398,313 - 73,482,913 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	71,254,907 - 71,339,508 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	73,479,863 - 73,524,956 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	73,378,662 - 73,524,956 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	73,147,273 - 73,203,947 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	74,078,683 - 74,123,668 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	18	74,151,955 - 74,196,941 (+)	NCBI
Celera	18	69,148,881 - 69,219,197 (+)	NCBI		Celera
Cytogenetic Map	18	q12.3	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

intellectual disability (ISO)

Microcephaly, Epilepsy, and Diabetes Syndrome (ISO)

Vici syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane (EXP,ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-hydroxy-17-methylestra-4,9,11-trien-3-one (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

4,4'-diaminodiphenylmethane (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

Aroclor 1254 (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

carbon nanotube (ISO)

CGP 52608 (ISO)

crocidolite asbestos (ISO)

diarsenic trioxide (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

enzyme inhibitor (ISO)

finasteride (EXP)

flutamide (EXP)

FR900359 (ISO)

furan (EXP)

gallic acid (ISO)

glyphosate (ISO)

hydrogen peroxide (ISO)

lead nitrate (ISO)

mercury atom (ISO)

mercury dichloride (ISO)

mercury(0) (ISO)

metformin (ISO)

methoxyacetic acid (EXP)

N-methyl-N-nitrosourea (ISO)

N-nitrosodiethylamine (EXP)

Nor-9-carboxy-delta9-THC (ISO)

okadaic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP)

phenethyl caffeate (EXP)

pirinixic acid (EXP,ISO)

SB 431542 (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

succimer (ISO)

sunitinib (ISO)

temozolomide (ISO)

testosterone (EXP)

theophylline (ISO)

thimerosal (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

androgen receptor signaling pathway (IMP)

DNA-templated transcription (IEA,ISO)

negative regulation of androgen receptor signaling pathway (IEA,ISO)

negative regulation of DNA-binding transcription factor activity (ISO)

positive regulation of dendrite morphogenesis (IMP)

positive regulation of DNA-templated transcription (IMP)

protein sumoylation (IBA,IEA,ISO,ISS)

regulation of androgen receptor signaling pathway (IDA)

regulation of DNA-templated transcription (IDA)

regulation of macromolecule metabolic process (IEA)

regulation of transcription by RNA polymerase II (IBA,IEA,ISO)

response to testosterone (IEP)

SMAD protein signal transduction (ISO)

spermatogenesis (IEP)

transforming growth factor beta receptor signaling pathway (ISO)

Cellular Component

chromatin (IBA)

nuclear body (IEA)

nuclear speck (IEA)

nucleoplasm (ISO)

nucleus (IDA,ISO)

PML body (IEA,ISO,ISS)

Molecular Function

DNA binding (IEA,ISO)

nuclear androgen receptor binding (IPI)

nuclear estrogen receptor binding (IPI)

nuclear glucocorticoid receptor binding (IPI)

protein binding (IPI,ISO)

protein domain specific binding (IPI)

RNA polymerase II-specific DNA-binding transcription factor binding (IEA,ISO)

SUMO ligase activity (IBA,IEA,ISO)

SUMO transferase activity (ISO)

transcription coregulator activity (IBA)

transferase activity (IEA)

ubiquitin protein ligase binding (IEA,ISO)

zinc ion binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

androgen signaling pathway (IMP)

hepatitis C pathway (IEA)

Jak-Stat signaling pathway (IEA,ISO)

small cell lung carcinoma pathway (IEA)

ubiquitin/proteasome degradation pathway (IEA)

External Pathway Database Links

KEGG Pathway

Hepatitis C

References

References - curated

#	Reference Title	Reference Citation
1.	Tollip is a mediator of protein sumoylation.	Ciarrocchi A, etal., PLoS One. 2009;4(2):e4404. Epub 2009 Feb 9.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	ARIP3 (androgen receptor-interacting protein 3) and other PIAS (protein inhibitor of activated STAT) proteins differ in their ability to modulate steroid receptor-dependent transcriptional activation.	Kotaja N, etal., Mol Endocrinol. 2000 Dec;14(12):1986-2000.
4.	Gene Data Set	MGD Curation, June 12, 2002
5.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
6.	A testis-specific androgen receptor coregulator that belongs to a novel family of nuclear proteins.	Moilanen AM, etal., J Biol Chem 1999 Feb 5;274(6):3700-4.
7.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
8.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
9.	GOA pipeline	RGD automated data pipeline
10.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
12.	PIASx is a MEF2 SUMO E3 ligase that promotes postsynaptic dendritic morphogenesis.	Shalizi A, etal., J Neurosci. 2007 Sep 12;27(37):10037-46.
13.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
14.	Pias1 interaction and sumoylation of metabotropic glutamate receptor 8.	Tang Z, etal., J Biol Chem. 2005 Nov 18;280(46):38153-9. Epub 2005 Sep 6.
15.	JAK/STAT signal transduction: regulators and implication in hematological malignancies.	Valentino L and Pierre J, Biochem Pharmacol. 2006 Mar 14;71(6):713-21. Epub 2006 Jan 19.
16.	Expression of the E3 SUMO-1 ligases PIASx and PIAS1 during spermatogenesis in the rat.	Yan W, etal., Gene Expr Patterns. 2003 Jun;3(3):301-8.

Additional References at PubMed

PMID:9256341	PMID:11104669	PMID:11477070	PMID:11893729	PMID:12077349	PMID:12855578	PMID:14752048	PMID:15489334	PMID:15767674	PMID:16352593	PMID:16522640	PMID:16675951
PMID:16777850	PMID:16816390	PMID:17283066	PMID:17623776	PMID:18579533	PMID:18628979	PMID:20408817	PMID:21630459	PMID:22082260	PMID:22406621	PMID:23145142	PMID:26175529
PMID:26581215	PMID:34947973

Genomics

Comparative Map Data

Pias2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	72,883,008 - 72,989,486 (+)	NCBI		GRCr8
mRatBN7.2	18	70,608,034 - 70,714,295 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	70,607,665 - 70,710,033 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	72,729,105 - 72,813,704 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	73,398,313 - 73,482,913 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	71,254,907 - 71,339,508 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	73,479,863 - 73,524,956 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	73,378,662 - 73,524,956 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	73,147,273 - 73,203,947 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	74,078,683 - 74,123,668 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	18	74,151,955 - 74,196,941 (+)	NCBI
Celera	18	69,148,881 - 69,219,197 (+)	NCBI		Celera
Cytogenetic Map	18	q12.3	NCBI

PIAS2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	18	46,803,218 - 46,920,145 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	18	46,803,218 - 46,920,160 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	18	44,383,181 - 44,500,108 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	18	42,646,058 - 42,751,464 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	18	41,199,736 - 41,278,688 (-)	NCBI		Celera
Cytogenetic Map	18	q21.1	NCBI
HuRef	18	41,247,384 - 41,354,863 (-)	NCBI		HuRef
CHM1_1	18	44,317,116 - 44,424,599 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	18	46,993,864 - 47,110,811 (-)	NCBI		T2T-CHM13v2.0

Pias2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	77,152,883 - 77,243,406 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	77,152,904 - 77,241,496 (+)	Ensembl		GRCm39 Ensembl
GRCm38	18	77,065,176 - 77,155,710 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	77,065,208 - 77,153,800 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	18	77,303,947 - 77,394,447 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	18	77,269,658 - 77,358,250 (+)	NCBI		MGSCv36	mm8
Celera	18	78,248,789 - 78,338,301 (+)	NCBI		Celera
Cytogenetic Map	18	E3	NCBI
cM Map	18	52.07	NCBI

Pias2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955402	32,270,348 - 32,358,312 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955402	32,263,616 - 32,358,532 (-)	NCBI	ChiLan1.0	ChiLan1.0

PIAS2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	17	64,208,389 - 64,339,057 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	18	49,900,990 - 50,031,671 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	18	40,067,901 - 40,196,078 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	18	43,622,455 - 43,728,675 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	18	43,622,455 - 43,728,675 (-)	Ensembl	panpan1.1		panPan2

PIAS2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	44,436,100 - 44,583,657 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	44,454,095 - 44,583,657 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	43,919,876 - 44,074,373 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	44,389,023 - 44,544,213 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	44,407,125 - 44,536,625 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	44,089,020 - 44,244,180 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	44,143,064 - 44,298,190 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	44,426,838 - 44,581,948 (+)	NCBI		UU_Cfam_GSD_1.0

Pias2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404944	40,745,308 - 40,828,055 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936517	82,332 - 144,586 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936517	72,676 - 152,926 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PIAS2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	96,441,676 - 96,545,780 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	96,401,635 - 96,545,798 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

PIAS2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	18	33,967,894 - 34,075,824 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	18	33,967,999 - 34,067,910 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	8,306,725 - 8,446,143 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pias2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624778	10,434,550 - 10,530,766 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624778	10,426,788 - 10,530,854 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Pias2
143 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	160
Count of miRNA genes:	125
Interacting mature miRNAs:	139
Transcripts:	ENSRNOT00000023886
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331733	Bp233	Blood pressure QTL 233	3.97196		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	24796977	79788953	Rat
12904069	Cm123	Cardiac mass QTL 123		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	18	52539763	76104388	Rat
12904070	Cm124	Cardiac mass QTL 124		0.01	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	18	52539763	76104388	Rat
2303584	Gluco55	Glucose level QTL 55	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	18	48520044	83828827	Rat
12904071	Am18	Aortic mass QTL 18		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	18	52539763	76104388	Rat
12904067	Cm122	Cardiac mass QTL 122		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	18	52539763	76104388	Rat
61384	Bp48	Blood pressure QTL 48	19.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	60622311	77209844	Rat
1331741	Bp232	Blood pressure QTL 232	3.59112		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	21372893	83213037	Rat
2301417	Bp319	Blood pressure QTL 319		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	52539763	76104388	Rat
1298072	Cia26	Collagen induced arthritis QTL 26	3.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	18	54709769	83828827	Rat
12904073	Kidm71	Kidney mass QTL 71		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	18	52539763	76104388	Rat
6903353	Bp353	Blood pressure QTL 353	2.8		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	59796478	83828827	Rat
738008	Hcar14	Hepatocarcinoma resistance QTL 14	4.3		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion number (CMO:0001462)	18	51464733	83218561	Rat
6903356	Bp354	Blood pressure QTL 354	4.6		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	59796478	83828827	Rat
631518	Bw11	Body weight QTL 11	2.8		body mass (VT:0001259)	body weight (CMO:0000012)	18	35870723	80870723	Rat
6893683	Bw110	Body weight QTL 110	2.7	0.002	body mass (VT:0001259)	body weight (CMO:0000012)	18	43345022	83828827	Rat
8694366	Abfw8	Abdominal fat weight QTL 8	6.38	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	18	46640675	83828827	Rat
2300157	Bmd66	Bone mineral density QTL 66	13.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	18	28964853	73964853	Rat
738005	Anxrr11	Anxiety related response QTL 11	3.4		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	18	30039813	75039813	Rat
631274	Sprol1	Serum protein level QTL 1	5.3		blood total protein amount (VT:0005567)	serum total protein level (CMO:0000661)	18	31393320	77209694	Rat
9589041	Epfw12	Epididymal fat weight QTL 12	17.08	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	18	46640675	83828827	Rat
8694432	Bw165	Body weight QTL 165	3.81	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	18	46640675	83828827	Rat
70185	BpQTLcluster15	Blood pressure QTL cluster 15	4.61		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	18	59712417	76477814	Rat
2293704	Bss35	Bone structure and strength QTL 35	4.59	0.0002	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	18	28964853	73964853	Rat
9589816	Gluco68	Glucose level QTL 68	7.25	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	18	29792965	74792965	Rat
1600373	Mamtr6	Mammary tumor resistance QTL 6			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	18	19278901	83218561	Rat
8694378	Bw157	Body weight QTL 157	3.59	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	18	29792965	74792965	Rat
1331770	Bp234	Blood pressure QTL 234	3.807		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	59796478	71893566	Rat
2303571	Bw92	Body weight QTL 92	3		body mass (VT:0001259)	body weight (CMO:0000012)	18	48520044	83828827	Rat
2300177	Bmd65	Bone mineral density QTL 65	19.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	18	28964853	73964853	Rat
1598826	Anxrr20	Anxiety related response QTL 20	3.04		body movement coordination trait (VT:0005424)	number of rearing movements in an experimental apparatus (CMO:0001752)	18	41432971	83828827	Rat
2301969	Bp324	Blood pressure QTL 324	4.05		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	59712417	76477814	Rat
631675	Iddm15	Insulin dependent diabetes mellitus QTL 15			urine glucose amount (VT:0001758)	percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)	18	60622311	77209844	Rat
1578667	Bss21	Bone structure and strength QTL 21	3.5		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	18	11791518	83218561	Rat
2303120	Mamtr8	Mammary tumor resistance QTL 8		0.001	mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	18	31359408	83218561	Rat
12880368	Bw187	Body weight QTL 187		0.045	body mass (VT:0001259)	body weight (CMO:0000012)	18	52539763	76104388	Rat
724542	Kidm2	Kidney mass QTL 2	2.6		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	18	59172115	83828827	Rat
61367	Iddm4	Insulin dependent diabetes mellitus QTL 4	2.33	0.0074	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	18	38192455	83192455	Rat
1359020	Ppulsi2	Prepulse inhibition QTL 2	2.71		prepulse inhibition trait (VT:0003088)	acoustic startle response measurement (CMO:0001519)	18	52292875	73997283	Rat
9590318	Scort22	Serum corticosterone level QTL 22	7.64	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	18	29792965	74792965	Rat
1578661	Bss20	Bone structure and strength QTL 20	3.7		femur morphology trait (VT:0000559)	femoral neck cross-sectional area (CMO:0001697)	18	11791518	83218561	Rat
1331754	Bp230	Blood pressure QTL 230	4.61609		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	29792965	74792965	Rat

Markers in Region

RH142489

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	70,687,279 - 70,687,454 (+)	MAPPER	mRatBN7.2
Rnor_6.0	18	73,514,926 - 73,515,100	NCBI	Rnor6.0
Rnor_5.0	18	73,182,346 - 73,182,520	UniSTS	Rnor5.0
RGSC_v3.4	18	74,113,747 - 74,113,921	UniSTS	RGSC3.4
Celera	18	69,209,257 - 69,209,431	UniSTS
RH 3.4 Map	18	747.0	UniSTS
Cytogenetic Map	18	q12.3	UniSTS

RH143406

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	70,687,846 - 70,687,946 (+)	MAPPER	mRatBN7.2
Rnor_6.0	18	73,515,493 - 73,515,592	NCBI	Rnor6.0
Rnor_5.0	18	73,182,913 - 73,183,012	UniSTS	Rnor5.0
RGSC_v3.4	18	74,114,314 - 74,114,413	UniSTS	RGSC3.4
Celera	18	69,209,824 - 69,209,923	UniSTS
RH 3.4 Map	18	748.5	UniSTS
Cytogenetic Map	18	q12.3	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001393764	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_053337	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039097142	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039097143	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039097144	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039097145	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039097146	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039097147	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039097149	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039097151	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039097152	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039097153	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039097154	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039097155	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277603	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277604	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277605	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277606	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277607	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277608	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277609	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277610	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277611	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277612	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277613	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC139391	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF044058	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC078775	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ225616	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ231412	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000023886 ⟹ ENSRNOP00000023886

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	70,626,661 - 70,703,964 (+)	Ensembl
Rnor_6.0 Ensembl	18	73,378,662 - 73,524,956 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000101274 ⟹ ENSRNOP00000097965

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	70,626,522 - 70,702,066 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000104069 ⟹ ENSRNOP00000092568

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	70,650,408 - 70,697,322 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000107723 ⟹ ENSRNOP00000092581

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	70,626,837 - 70,703,977 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000110007 ⟹ ENSRNOP00000086650

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	70,607,665 - 70,703,977 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000119543 ⟹ ENSRNOP00000097087

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	70,626,522 - 70,710,033 (+)	Ensembl

RefSeq Acc Id:

NM_001393764 ⟹ NP_001380693

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	72,901,707 - 72,986,278 (+)	NCBI
mRatBN7.2	18	70,626,511 - 70,711,087 (+)	NCBI

RefSeq Acc Id:

NM_053337 ⟹ NP_445789

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	72,901,707 - 72,973,996 (+)	NCBI
mRatBN7.2	18	70,626,511 - 70,698,805 (+)	NCBI
Rnor_6.0	18	73,479,863 - 73,524,956 (+)	NCBI
Rnor_5.0	18	73,147,273 - 73,203,947 (+)	NCBI
RGSC_v3.4	18	74,078,683 - 74,123,668 (+)	RGD
Celera	18	69,148,881 - 69,219,197 (+)	RGD

Sequence:

show sequence

CCCGCCGCGTCTAGAGCGGCGCCCAGTGCAGGATGTTGCAGGAGACGGCGGCGGTGTCGTTGGC
GGTAGCGGGCGGAGGAGCGGTGACGGCTGAGGCGCCCGCGGGCGGGATAAAATGGCGGATTTCG
AGGAGTTGAGGAATATGGTTTCTAGTTTTAGGGTTTCTGAATTACAAGTGTTACTGGGCTTTGC
TGGACGGAATAAAAGTGGGCGCAAGCATGACCTCCTGATGAGGGCGTTGCATTTACTGAAGAGT
GGCTGCAGCCCTGCGGTTCAGATTAAAATTCGAGAATTATACAGACGCCGATACCCACGGACAC
TTGAAGGACTTTCTGATCTATCCACAATCAAATCTTCAGTTTTCAGTTTGGATGGTAGCTCATC
ACCAGTAGAGCCTGACTTGGCCGTGGCTGGGATCCACTCGTTGCCTTCTACTTCCATTGCACCT
CATTCACCGTCATCTCCTGTCGCTTCTGTGCTGCTTCAAGACACTAAGCCCACGTTTGAGATGC
AGCAACCATCTCCTCCCATTCCTCCTGTCCATCCTGACGTGCAGTTAAAAACGCTGCCCTTCTA
TGACGTCCTTGATGTTCTCATCAAGCCCACAAGTTTAGTTCAAAGCAGTATTCAGCGGTTTCAA
GAGAAGTTTTTTATTTTTGCTTTGACACCCCAGCAAGTTAGAGAGATATGCATTTCAAGGGATT
TTTTGCCAGGTGGCAGGAGAGACTACACAGTCCAAGTCCAGCTGCGACTTTGCTTGGCAGAGAC
CAGTTGCCCTCAAGAAGATAACTATCCCAATAGTTTGTGTATAAAAGTAAATGGGAAACTCTTT
CCTTTGCCTGGCTATGCACCACCACCTAAAAATGGGATCGAACAGAAGCGTCCTGGACGCCCCC
TGAATATTACATCTTTAGTGAGATTGTCTTCAGCTGTGCCAAATCAGATTTCTATTTCTTGGGC
ATCTGAAATTGGAAAGAATTACTCCATGTCTGTGTATCTTGTACGACAGCTTACATCAGCCATG
TTATTACAGAGATTAAAAATGAAAGGTATTAGAAATCCTGATCATTCCAAAGCACTCATTAAAG
AAAAACTTACTGCAGATCCTGATAGTGAAATTGCTACAACTAGTCTTCGAGTGTCCTTGATGTG
CCCTTTAGGAAAAATGAGGCTGACAATCCCGTGCCGCGCAGTGACGTGTACACATCTGCAGTGC
TTTGATGCTGCCCTGTATCTTCAGATGAATGAGAAGAAGCCCACCTGGATTTGTCCTGTTTGTG
ACAAAAAGGCTGCCTATGAGAGTCTGATACTAGATGGGCTTTTTATGGAAATTCTCAATGACTG
TTCTGATGTGGATGAGATCAAATTCCAGGAAGATGGTTCCTGGTGCCCCATGAGACCTAAGAAA
GAAGCTATGAAAGTAACCAGCCAGCCCTGTACAAAAGTAGAAAGTTCAAGTGTCTTTAGTAAAC
CTTGTTCAGTGACTGTAGCCAGTGATGCAAGCAAGAAGAAGATTGATGTTATTGATCTAACAAT
AGAGAGCTCTTCTGATGAAGAGGAAGACCCTCCCGCCAAAAGGAAATGCATCTTTATGTCAGAA
ACACAAAGCAGTCCAACCAAAGGGGTTCTCATGTATCAGCCATCTTCTGTAAGGGTGCCCAGTG
TGACTTCAGTTGATCCTGCTGCTATTCCACCTTCATTAACAGACTACTCAGTACCATTCCACCA
CACGCCAGTGTCGAGCATGTCATCAGATTTGCCAGGAGAACAAAGAAGAAATGATATTAATAAC
GAAGTGCAGCTTGGAACATCTTCTGATACTGTGCAACAGTGAATGCAAAATAAAACAKAATTTG
TA

hide sequence

RefSeq Acc Id:

XM_039097142 ⟹ XP_038953070

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	72,883,008 - 72,981,336 (+)	NCBI
mRatBN7.2	18	70,619,281 - 70,707,414 (+)	NCBI

RefSeq Acc Id:

XM_039097143 ⟹ XP_038953071

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	72,883,008 - 72,981,336 (+)	NCBI
mRatBN7.2	18	70,619,281 - 70,707,414 (+)	NCBI

RefSeq Acc Id:

XM_039097144 ⟹ XP_038953072

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	72,883,192 - 72,981,336 (+)	NCBI
mRatBN7.2	18	70,608,034 - 70,707,414 (+)	NCBI

RefSeq Acc Id:

XM_039097145 ⟹ XP_038953073

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	72,883,008 - 72,972,505 (+)	NCBI
mRatBN7.2	18	70,619,281 - 70,699,490 (+)	NCBI

RefSeq Acc Id:

XM_039097146 ⟹ XP_038953074

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	72,883,008 - 72,989,486 (+)	NCBI
mRatBN7.2	18	70,619,281 - 70,714,295 (+)	NCBI

RefSeq Acc Id:

XM_039097147 ⟹ XP_038953075

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	72,897,237 - 72,981,336 (+)	NCBI
mRatBN7.2	18	70,625,934 - 70,707,414 (+)	NCBI

RefSeq Acc Id:

XM_039097149 ⟹ XP_038953077

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	72,902,007 - 72,981,336 (+)	NCBI
mRatBN7.2	18	70,626,828 - 70,707,414 (+)	NCBI

RefSeq Acc Id:

XM_039097151 ⟹ XP_038953079

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	72,883,008 - 72,978,278 (+)	NCBI
mRatBN7.2	18	70,619,281 - 70,703,112 (+)	NCBI

RefSeq Acc Id:

XM_039097152 ⟹ XP_038953080

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	72,883,008 - 72,978,278 (+)	NCBI
mRatBN7.2	18	70,619,281 - 70,707,414 (+)	NCBI

RefSeq Acc Id:

XM_039097153 ⟹ XP_038953081

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	72,883,008 - 72,978,278 (+)	NCBI
mRatBN7.2	18	70,619,281 - 70,703,129 (+)	NCBI

RefSeq Acc Id:

XM_039097154 ⟹ XP_038953082

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	72,883,008 - 72,989,486 (+)	NCBI
mRatBN7.2	18	70,619,281 - 70,714,295 (+)	NCBI

RefSeq Acc Id:

XM_039097155 ⟹ XP_038953083

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	72,883,008 - 72,972,505 (+)	NCBI
mRatBN7.2	18	70,619,281 - 70,700,109 (+)	NCBI

RefSeq Acc Id:

XM_063277603 ⟹ XP_063133673

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	72,883,008 - 72,981,336 (+)	NCBI

RefSeq Acc Id:

XM_063277604 ⟹ XP_063133674

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	72,883,102 - 72,981,336 (+)	NCBI

RefSeq Acc Id:

XM_063277605 ⟹ XP_063133675

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	72,901,986 - 72,981,336 (+)	NCBI

RefSeq Acc Id:

XM_063277606 ⟹ XP_063133676

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	72,883,102 - 72,972,505 (+)	NCBI

RefSeq Acc Id:

XM_063277607 ⟹ XP_063133677

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	72,897,237 - 72,981,336 (+)	NCBI

RefSeq Acc Id:

XM_063277608 ⟹ XP_063133678

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	72,901,986 - 72,981,336 (+)	NCBI

RefSeq Acc Id:

XM_063277609 ⟹ XP_063133679

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	72,897,237 - 72,989,486 (+)	NCBI

RefSeq Acc Id:

XM_063277610 ⟹ XP_063133680

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	72,902,007 - 72,972,505 (+)	NCBI

RefSeq Acc Id:

XM_063277611 ⟹ XP_063133681

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	72,897,237 - 72,978,278 (+)	NCBI

RefSeq Acc Id:

XM_063277612 ⟹ XP_063133682

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	72,897,237 - 72,972,505 (+)	NCBI

RefSeq Acc Id:

XM_063277613 ⟹ XP_063133683

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	72,902,007 - 72,972,505 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001380693	(Get FASTA)	NCBI Sequence Viewer
	NP_445789	(Get FASTA)	NCBI Sequence Viewer
	XP_038953070	(Get FASTA)	NCBI Sequence Viewer
	XP_038953071	(Get FASTA)	NCBI Sequence Viewer
	XP_038953072	(Get FASTA)	NCBI Sequence Viewer
	XP_038953073	(Get FASTA)	NCBI Sequence Viewer
	XP_038953074	(Get FASTA)	NCBI Sequence Viewer
	XP_038953075	(Get FASTA)	NCBI Sequence Viewer
	XP_038953077	(Get FASTA)	NCBI Sequence Viewer
	XP_038953079	(Get FASTA)	NCBI Sequence Viewer
	XP_038953080	(Get FASTA)	NCBI Sequence Viewer
	XP_038953081	(Get FASTA)	NCBI Sequence Viewer
	XP_038953082	(Get FASTA)	NCBI Sequence Viewer
	XP_038953083	(Get FASTA)	NCBI Sequence Viewer
	XP_063133673	(Get FASTA)	NCBI Sequence Viewer
	XP_063133674	(Get FASTA)	NCBI Sequence Viewer
	XP_063133675	(Get FASTA)	NCBI Sequence Viewer
	XP_063133676	(Get FASTA)	NCBI Sequence Viewer
	XP_063133677	(Get FASTA)	NCBI Sequence Viewer
	XP_063133678	(Get FASTA)	NCBI Sequence Viewer
	XP_063133679	(Get FASTA)	NCBI Sequence Viewer
	XP_063133680	(Get FASTA)	NCBI Sequence Viewer
	XP_063133681	(Get FASTA)	NCBI Sequence Viewer
	XP_063133682	(Get FASTA)	NCBI Sequence Viewer
	XP_063133683	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAD13349	(Get FASTA)	NCBI Sequence Viewer
	AAH78775	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000023886.5
	ENSRNOP00000086650.1
	ENSRNOP00000092568.1
	ENSRNOP00000092581.1
	ENSRNOP00000097087.1
	ENSRNOP00000097965.1
GenBank Protein	Q6AZ28	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_445789 ⟸ NM_053337
- Peptide Label:	isoform 2
- UniProtKB:	Q9Z177 (UniProtKB/Swiss-Prot), Q6AZ28 (UniProtKB/Swiss-Prot), A6KMU1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MADFEELRNMVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIKIRELYRRR YPRTLEGLSDLSTIKSSVFSLDGSSSPVEPDLAVAGIHSLPSTSIAPHSPSSPVASVLLQDTKP TFEMQQPSPPIPPVHPDVQLKTLPFYDVLDVLIKPTSLVQSSIQRFQEKFFIFALTPQQVREIC ISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFPLPGYAPPPKNGIEQKR PGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSK ALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWI CPVCDKKAAYESLILDGLFMEILNDCSDVDEIKFQEDGSWCPMRPKKEAMKVTSQPCTKVESSS VFSKPCSVTVASDASKKKIDVIDLTIESSSDEEEDPPAKRKCIFMSETQSSPTKGVLMYQPSSV RVPSVTSVDPAAIPPSLTDYSVPFHHTPVSSMSSDLPGEQRRNDINNEVQLGTSSDTVQQ hide sequence

Ensembl Acc Id:

ENSRNOP00000023886 ⟸ ENSRNOT00000023886

RefSeq Acc Id:	XP_038953072 ⟸ XM_039097144
- Peptide Label:	isoform X4
- UniProtKB:	A6KMU4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038953074 ⟸ XM_039097146
- Peptide Label:	isoform X7

RefSeq Acc Id:	XP_038953082 ⟸ XM_039097154
- Peptide Label:	isoform X11

RefSeq Acc Id:	XP_038953070 ⟸ XM_039097142
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038953071 ⟸ XM_039097143
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038953080 ⟸ XM_039097152
- Peptide Label:	isoform X11

RefSeq Acc Id:	XP_038953081 ⟸ XM_039097153
- Peptide Label:	isoform X11

RefSeq Acc Id:	XP_038953079 ⟸ XM_039097151
- Peptide Label:	isoform X11

RefSeq Acc Id:	XP_038953083 ⟸ XM_039097155
- Peptide Label:	isoform X12

RefSeq Acc Id:	XP_038953073 ⟸ XM_039097145
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_038953075 ⟸ XM_039097147
- Peptide Label:	isoform X8
- UniProtKB:	A6KMU4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038953077 ⟸ XM_039097149
- Peptide Label:	isoform X9
- UniProtKB:	A6KMU2 (UniProtKB/TrEMBL), A6KMU4 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000092581 ⟸ ENSRNOT00000107723

Ensembl Acc Id:

ENSRNOP00000092568 ⟸ ENSRNOT00000104069

Ensembl Acc Id:

ENSRNOP00000097087 ⟸ ENSRNOT00000119543

Ensembl Acc Id:

ENSRNOP00000086650 ⟸ ENSRNOT00000110007

Ensembl Acc Id:

ENSRNOP00000097965 ⟸ ENSRNOT00000101274

RefSeq Acc Id:	NP_001380693 ⟸ NM_001393764
- Peptide Label:	isoform 1
- UniProtKB:	A6KMU4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063133673 ⟸ XM_063277603
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_063133674 ⟸ XM_063277604
- Peptide Label:	isoform X5
- UniProtKB:	A0A8I6A470 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063133676 ⟸ XM_063277606
- Peptide Label:	isoform X13

RefSeq Acc Id:	XP_063133679 ⟸ XM_063277609
- Peptide Label:	isoform X16
- UniProtKB:	A0A8I6GLW8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063133677 ⟸ XM_063277607
- Peptide Label:	isoform X14

RefSeq Acc Id:	XP_063133681 ⟸ XM_063277611
- Peptide Label:	isoform X18

RefSeq Acc Id:	XP_063133682 ⟸ XM_063277612
- Peptide Label:	isoform X19

RefSeq Acc Id:	XP_063133675 ⟸ XM_063277605
- Peptide Label:	isoform X10
- UniProtKB:	A0A8I6GK87 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063133678 ⟸ XM_063277608
- Peptide Label:	isoform X15

RefSeq Acc Id:	XP_063133680 ⟸ XM_063277610
- Peptide Label:	isoform X17
- UniProtKB:	A6KMU3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063133683 ⟸ XM_063277613
- Peptide Label:	isoform X20

Protein Domains

PINIT SAP SP-RING-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6AZ28-F1-model_v2	AlphaFold	Q6AZ28	1-572	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:71056	AgrOrtholog
BioCyc Gene	G2FUF-6946	BioCyc
Ensembl Genes	ENSRNOG00000017493	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000023886.6	UniProtKB/TrEMBL
	ENSRNOT00000101274.1	UniProtKB/TrEMBL
	ENSRNOT00000104069.1	UniProtKB/TrEMBL
	ENSRNOT00000107723.1	UniProtKB/TrEMBL
	ENSRNOT00000110007.1	UniProtKB/TrEMBL
	ENSRNOT00000119543.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.720.30	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	2.60.120.780	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.30.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7111628	IMAGE-MGC_LOAD
InterPro	PINIT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PINIT_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SAP_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SAP_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_MIZ	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:83422	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:93310	IMAGE-MGC_LOAD
NCBI Gene	83422	ENTREZGENE
PANTHER	PTHR10782:SF12	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	PINIT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	zf-MIZ	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Pias2	PhenoGen
PROSITE	PINIT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SAP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZF_SP_RING	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000017493	RatGTEx
SMART	SAP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF68906	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I6A470	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AHS4_RAT	UniProtKB/TrEMBL
	A0A8I6B6K3_RAT	UniProtKB/TrEMBL
	A0A8I6GK87	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GLW8	ENTREZGENE, UniProtKB/TrEMBL
	A6KMU1	ENTREZGENE, UniProtKB/TrEMBL
	A6KMU2	ENTREZGENE, UniProtKB/TrEMBL
	A6KMU3	ENTREZGENE, UniProtKB/TrEMBL
	A6KMU4	ENTREZGENE, UniProtKB/TrEMBL
	A6KMU6_RAT	UniProtKB/TrEMBL
	F1LRP3_RAT	UniProtKB/TrEMBL
	PIAS2_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
	Q9Z177	ENTREZGENE
UniProt Secondary	Q9Z177	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2009-02-06	Pias2	protein inhibitor of activated STAT, 2	Pias2	protein inhibitor of activated STAT 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-18	Pias2	protein inhibitor of activated STAT 2	Miz1	Msx-interacting-zinc finger	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2002-07-09	Miz1	Msx-interacting-zinc finger			Symbol and Name updated to reflect Human and Mouse nomenclature	70877	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_physical_interaction	binds to DNA-binding domain/zinc finger region of androgen receptor	70792
gene_protein	572 amino acids	70792

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

RGD Manual Annotations

Imported Annotations - KEGG (archival)

External Pathway Database Links

External Pathway Database Links

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Imported Disease Annotations - ClinVar

RGD Manual Annotations

Imported Annotations - KEGG (archival)

External Pathway Database Links

External Pathway Database Links