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Gene: Pias2 (protein inhibitor of activated STAT 2) Mus musculus
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Symbol: Pias2
Name: protein inhibitor of activated STAT 2
Description: Exhibits several functions, including SUMO transferase activity; transcription factor binding activity; and ubiquitin protein ligase binding activity. Involved in several processes, including positive regulation of transcription by RNA polymerase II; protein sumoylation; and regulation of osteoblast differentiation. Localizes to the nuclear body. Predicted to colocalize with the PML body. Is expressed in several structures, including branchial arch; central nervous system; early conceptus; embryo mesenchyme; and genitourinary system. Orthologous to human PIAS2 (protein inhibitor of activated STAT 2); PARTICIPATES IN Jak-Stat signaling pathway; hepatitis C pathway; small cell lung carcinoma pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 2,3',4,4',5-Pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 6330408K17Rik; AI462206; androgen receptor-interacting protein 3; ARIP3; AU018068; DAB2-interacting protein; Dib; DIP; E3 SUMO-protein ligase PIAS2; Miz1; msx-interacting zinc finger protein; Msx-interacting-zinc finger; PIASxalpha; PIASxalpha6; PIASxb; PIASxbeta; protein inhibitor of activated STAT x; RING-type E3 ubiquitin transferase PIAS2; SIZ2
Orthologs:
Homo sapiens (human) : PIAS2 (protein inhibitor of activated STAT 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pias2 (protein inhibitor of activated STAT, 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pias2 (protein inhibitor of activated STAT 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PIAS2 (protein inhibitor of activated STAT 2)
Canis lupus familiaris (dog) : PIAS2 (protein inhibitor of activated STAT 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pias2 (protein inhibitor of activated STAT 2)
Sus scrofa (pig) : PIAS2 (protein inhibitor of activated STAT 2)
Chlorocebus sabaeus (African green monkey) : PIAS2 (protein inhibitor of activated STAT 2)
Heterocephalus glaber (naked mole-rat) : Pias2 (protein inhibitor of activated STAT 2)
more info ...
Related Pseudogenes: Gm9038  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1877,065,208 - 77,153,800 (+)Ensembl
GRCm381877,065,176 - 77,155,710 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371877,303,947 - 77,394,447 (+)NCBIGRCm37mm9NCBIm37
MGSCv361877,269,658 - 77,358,250 (+)NCBImm8
Celera1878,248,789 - 78,338,301 (+)NCBICelera
Cytogenetic Map18 E3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Pias2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735930
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.