Symbol:
Card11
Name:
caspase recruitment domain family, member 11
RGD ID:
2323211
Description:
Predicted to enable CARD domain binding activity. Predicted to be involved in several processes, including intracellular signal transduction; positive regulation of NF-kappaB transcription factor activity; and positive regulation of signal transduction. Predicted to act upstream of or within several processes, including lymphocyte differentiation; positive regulation of interleukin-2 production; and regulation of lymphocyte activation. Predicted to be located in cytoplasm; membrane raft; and plasma membrane. Predicted to be part of CBM complex. Predicted to be active in immunological synapse. Human ortholog(s) of this gene implicated in diffuse large B-cell lymphoma; immunodeficiency 11A; and immunodeficiency 11B. Orthologous to human CARD11 (caspase recruitment domain family member 11); PARTICIPATES IN B cell receptor signaling pathway; T cell receptor signaling pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; acetamiprid.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
caspase recruitment domain-containing protein 11; LOC100363332
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 12 18,735,088 - 18,872,045 (+) NCBI GRCr8 mRatBN7.2 12 13,621,140 - 13,758,115 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 12 13,621,087 - 13,758,112 (+) Ensembl mRatBN7.2 Ensembl Rnor_6.0 12 15,700,600 - 15,844,512 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 12 15,700,825 - 15,844,512 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 12 17,780,109 - 17,843,748 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 12 14,165,040 - 14,229,267 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 Celera 12 15,382,300 - 15,519,160 (+) NCBI Celera Cytogenetic Map 12 q11 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Imported Annotations - KEGG (archival)
Card11 Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 12 18,735,088 - 18,872,045 (+) NCBI GRCr8 mRatBN7.2 12 13,621,140 - 13,758,115 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 12 13,621,087 - 13,758,112 (+) Ensembl mRatBN7.2 Ensembl Rnor_6.0 12 15,700,600 - 15,844,512 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 12 15,700,825 - 15,844,512 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 12 17,780,109 - 17,843,748 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 12 14,165,040 - 14,229,267 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 Celera 12 15,382,300 - 15,519,160 (+) NCBI Celera Cytogenetic Map 12 q11 NCBI
CARD11 Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 7 2,906,142 - 3,043,867 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 7 2,906,142 - 3,044,228 (-) Ensembl GRCh38 hg38 GRCh38 GRCh37 7 2,945,776 - 3,083,501 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 7 2,912,295 - 3,050,105 (-) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 7 2,719,023 - 2,856,711 NCBI Celera 7 2,914,379 - 3,052,190 (-) NCBI Celera Cytogenetic Map 7 p22.2 NCBI HuRef 7 2,863,784 - 3,002,087 (-) NCBI HuRef CHM1_1 7 2,945,368 - 3,083,717 (-) NCBI CHM1_1 T2T-CHM13v2.0 7 3,019,747 - 3,157,416 (-) NCBI T2T-CHM13v2.0 CRA_TCAGchr7v2 7 2,993,579 - 3,131,390 (-) NCBI
Card11 Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 5 140,858,109 - 140,986,398 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 5 140,858,745 - 140,986,337 (-) Ensembl GRCm39 Ensembl GRCm38 5 140,872,999 - 141,000,596 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 5 140,872,990 - 141,000,582 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 5 141,348,953 - 141,476,550 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 5 141,125,473 - 141,252,966 (-) NCBI MGSCv36 mm8 Celera 5 137,928,048 - 138,050,352 (-) NCBI Celera Cytogenetic Map 5 G2 NCBI cM Map 5 79.42 NCBI
Card11 Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955460 12,368,918 - 12,490,041 (+) Ensembl ChiLan1.0 ChiLan1.0 NW_004955460 12,368,987 - 12,487,675 (+) NCBI ChiLan1.0 ChiLan1.0
CARD11 Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 6 7,863,477 - 8,001,993 (-) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 7 56,188,181 - 56,326,694 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 7 3,166,788 - 3,304,729 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 7 3,258,736 - 3,395,626 (-) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 7 3,258,736 - 3,332,999 (-) Ensembl panpan1.1 panPan2
CARD11 Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 6 14,273,115 - 14,331,029 (+) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 6 14,210,114 - 14,332,094 (+) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 6 15,666,400 - 15,792,761 (+) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 6 14,329,524 - 14,455,900 (+) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 6 14,335,283 - 14,455,892 (+) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 6 14,134,984 - 14,261,297 (+) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 6 14,061,830 - 14,188,602 (+) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 6 14,347,905 - 14,474,301 (+) NCBI UU_Cfam_GSD_1.0
Card11
CARD11
LOC103246958
Card11
.
Predicted Target Of
Count of predictions: 208 Count of miRNA genes: 95 Interacting mature miRNAs: 100 Transcripts: ENSRNOT00000051382, ENSRNOT00000065894 Prediction methods: Microtar, Miranda, Rnahybrid, Targetscan Result types: miRGate_prediction
2312418 Kidm41 Kidney mass QTL 41 3.7 0.0001 kidney mass (VT:0002707) single kidney wet weight to body weight ratio (CMO:0000622) 12 1 19611090 Rat 8552964 Pigfal17 Plasma insulin-like growth factor 1 level QTL 17 3.5 blood insulin-like growth factor amount (VT:0010479) plasma insulin-like growth factor 1 level (CMO:0001299) 12 5564495 46669029 Rat 7411641 Foco19 Food consumption QTL 19 27.7 0.001 eating behavior trait (VT:0001431) feed conversion ratio (CMO:0001312) 12 5564495 46669029 Rat 1549912 Bp268 Blood pressure QTL 268 arterial blood pressure trait (VT:2000000) diastolic blood pressure (CMO:0000005) 10 13182736 46669029 Rat 2302060 Pia37 Pristane induced arthritis QTL 37 6.1 0.001 blood immunoglobulin amount (VT:0002460) serum immunoglobulin G1 level (CMO:0002115) 12 13198157 46669029 Rat 9590147 Scort7 Serum corticosterone level QTL 7 13.61 0.001 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 12 1 42110980 Rat 1641928 Alcrsp5 Alcohol response QTL 5 response to alcohol trait (VT:0010489) duration of loss of righting reflex (CMO:0002289) 12 12812385 46669029 Rat 8552912 Pigfal6 Plasma insulin-like growth factor 1 level QTL 6 5 blood insulin-like growth factor amount (VT:0010479) plasma insulin-like growth factor 1 level (CMO:0001299) 12 5564498 46669029 Rat 1549829 Scl48 Serum cholesterol level QTL 48 5 blood cholesterol amount (VT:0000180) serum total cholesterol level (CMO:0000363) 12 9603277 46669029 Rat 10059594 Kidm46 Kidney mass QTL 46 3.79 0.025 kidney mass (VT:0002707) both kidneys wet weight to body weight ratio (CMO:0000340) 12 6107579 46669029 Rat 61331 Eau2 Experimental allergic uveoretinitis QTL 2 0.0005 uvea integrity trait (VT:0010551) experimental autoimmune uveitis score (CMO:0001504) 12 8525423 28064601 Rat 1581516 Cm56 Cardiac mass QTL 56 4.2 0.05 heart left ventricle mass (VT:0007031) heart left ventricle weight to body weight ratio (CMO:0000530) 12 1 29333307 Rat 9590086 Insglur6 Insulin/glucose ratio QTL 6 18.97 0.001 blood insulin amount (VT:0001560) calculated plasma insulin level (CMO:0002170) 12 1 42110980 Rat 8552918 Pigfal7 Plasma insulin-like growth factor 1 level QTL 7 blood insulin-like growth factor amount (VT:0010479) plasma insulin-like growth factor 1 level (CMO:0001299) 12 5564495 46669029 Rat 6893681 Bw109 Body weight QTL 109 2.3 0.004 body mass (VT:0001259) body weight (CMO:0000012) 12 1 23297788 Rat 1549902 Bp269 Blood pressure QTL 269 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 12 13182736 46669029 Rat 1302792 Scl21 Serum cholesterol level QTL 21 3.8 0.0011 blood cholesterol amount (VT:0000180) plasma total cholesterol level (CMO:0000585) 12 7196730 46669029 Rat 61404 Bw120 Body weight QTL 120 5.1 body mass (VT:0001259) body mass index (BMI) (CMO:0000105) 12 12351619 46669029 Rat 1331786 Kidm11 Kidney mass QTL 11 3.571 kidney mass (VT:0002707) right kidney wet weight (CMO:0000082) 12 11073825 24234895 Rat 1598855 Bp294 Blood pressure QTL 294 3.5 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 12 1 34851688 Rat 1600391 Edcs2 Endometrial carcinoma susceptibility QTL2 3.5 0.01 uterus morphology trait (VT:0001120) percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759) 12 6833190 17870186 Rat 2293699 Bss49 Bone structure and strength QTL 49 5.61 0.0001 lumbar vertebra size trait (VT:0010518) lumbar vertebra trabecular cross-sectional area (CMO:0001692) 12 10474137 46669029 Rat 10755457 Coatc14 Coat color QTL 14 0.01759 coat/hair pigmentation trait (VT:0010463) pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812) 12 1 22591684 Rat 1331761 Bp218 Blood pressure QTL 218 2.973 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 12 11073825 45055165 Rat 634351 Apr5 Acute phase response QTL 5 6.7 blood interleukin-6 amount (VT:0008595) plasma interleukin-6 level (CMO:0001927) 12 1 44503507 Rat 8694179 Bw150 Body weight QTL 150 2.9 0.001 body mass (VT:0001259) body weight gain (CMO:0000420) 12 1 42110980 Rat 634350 Apr4 Acute phase response QTL 4 6 orosomucoid 1 amount (VT:0010541) plasma orosomucoid 1 level (CMO:0001467) 12 1172005 46172005 Rat 7411545 Bw128 Body weight QTL 128 5.2 0.001 body mass (VT:0001259) body weight gain (CMO:0000420) 12 1 42110980 Rat 61416 Pia4 Pristane induced arthritis QTL 4 8.4 joint integrity trait (VT:0010548) arthritic paw count (CMO:0001460) 12 13635523 30827399 Rat 7204484 Bp358 Blood pressure QTL 358 0.001 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 12 13008296 19212979 Rat 7411547 Bw129 Body weight QTL 129 0.001 body mass (VT:0001259) body weight gain (CMO:0000420) 6 5564495 46669029 Rat 7387292 Kidm42 Kidney mass QTL 42 3.03 0.0004 kidney mass (VT:0002707) left kidney wet weight (CMO:0000083) 12 1 36247923 Rat 61421 Cia12 Collagen induced arthritis QTL 12 4.6 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 12 13635523 35682913 Rat 1300157 Rf21 Renal function QTL 21 4.4 renal blood flow trait (VT:2000006) absolute change in renal blood flow rate (CMO:0001168) 12 9318216 32103380 Rat 737979 Pia22 Pristane induced arthritis QTL 22 53.1 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 12 1 44465750 Rat 2303569 Gluco44 Glucose level QTL 44 2 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 12 12812385 46669029 Rat 7411586 Foco5 Food consumption QTL 5 5.4 0.001 eating behavior trait (VT:0001431) feed conversion ratio (CMO:0001312) 12 1 42110980 Rat 2303575 Insul14 Insulin level QTL 14 4 blood insulin amount (VT:0001560) blood insulin level (CMO:0000349) 12 1 42450532 Rat 7411588 Foco6 Food consumption QTL 6 0.001 eating behavior trait (VT:0001431) feed conversion ratio (CMO:0001312) 12 5564495 46669029 Rat 2302042 Pia38 Pristane induced arthritis QTL 38 3.5 0.001 blood immunoglobulin amount (VT:0002460) serum immunoglobulin G1 level (CMO:0002115) 12 1 44503507 Rat 2300186 Bmd59 Bone mineral density QTL 59 7.1 0.0001 lumbar vertebra mineral mass (VT:0010511) volumetric bone mineral density (CMO:0001553) 12 10474137 46669029 Rat 7411595 Foco9 Food consumption QTL 9 4 0.001 eating behavior trait (VT:0001431) feed conversion ratio (CMO:0001312) 12 1 42110980 Rat 7411597 Foco10 Food consumption QTL 10 0.001 eating behavior trait (VT:0001431) feed conversion ratio (CMO:0001312) 12 5564495 46669029 Rat 2293086 Iddm30 Insulin dependent diabetes mellitus QTL 30 3.82 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 12 8449490 28302290 Rat 7411660 Foco28 Food consumption QTL 28 10.9 0.001 eating behavior trait (VT:0001431) feed conversion ratio (CMO:0001312) 12 1 42110980 Rat 1331755 Bp219 Blood pressure QTL 219 3.041 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 12 11073825 28064557 Rat
D12Wox5
Rat Assembly Chr Position (strand) Source JBrowse GRCr8 12 18,749,469 - 18,749,604 (+) Marker Load Pipeline mRatBN7.2 12 13,635,523 - 13,635,658 (+) MAPPER mRatBN7.2 Rnor_6.0 12 15,714,609 - 15,714,743 NCBI Rnor6.0 Rnor_5.0 12 17,721,341 - 17,721,475 UniSTS Rnor5.0 Celera 12 15,396,902 - 15,397,046 UniSTS RH 3.4 Map 12 175.8 RGD RH 3.4 Map 12 175.8 UniSTS RH 2.0 Map 12 146.0 RGD Cytogenetic Map 12 q11 UniSTS
RH139757
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 12 13,757,866 - 13,758,064 (+) MAPPER mRatBN7.2 Rnor_6.0 12 15,844,264 - 15,844,461 NCBI Rnor6.0 Rnor_5.0 12 17,843,500 - 17,843,697 UniSTS Rnor5.0 RGSC_v3.4 12 14,229,021 - 14,229,218 UniSTS RGSC3.4 Celera 12 15,518,912 - 15,519,109 UniSTS RH 3.4 Map 12 176.5 UniSTS Cytogenetic Map 12 q11 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
11
49
113
91
90
59
25
59
6
218
97
93
45
60
31
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENSRNOT00000051382
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 12 13,694,854 - 13,758,112 (+) Ensembl Rnor_6.0 Ensembl 12 15,802,564 - 15,844,173 (+) Ensembl
Ensembl Acc Id:
ENSRNOT00000092808
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source Rnor_6.0 Ensembl 12 15,839,918 - 15,844,512 (+) Ensembl
Ensembl Acc Id:
ENSRNOT00000092970
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 12 13,621,087 - 13,758,112 (+) Ensembl Rnor_6.0 Ensembl 12 15,700,825 - 15,838,308 (+) Ensembl
RefSeq Acc Id:
NM_001419863 ⟹ NP_001406792
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 12 18,735,088 - 18,872,045 (+) NCBI mRatBN7.2 12 13,621,140 - 13,758,115 (+) NCBI
RefSeq Acc Id:
XM_039089959 ⟹ XP_038945887
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 12 18,789,030 - 18,872,043 (+) NCBI mRatBN7.2 12 13,674,670 - 13,758,115 (+) NCBI
RefSeq Acc Id:
XP_038945887 ⟸ XM_039089959
- Peptide Label:
isoform X1
- UniProtKB:
A0A8I5ZNJ6 (UniProtKB/TrEMBL), A0A8I6AA96 (UniProtKB/TrEMBL)
RefSeq Acc Id:
NP_001406792 ⟸ NM_001419863
- UniProtKB:
A0A8I5ZNJ6 (UniProtKB/TrEMBL), A0A8I6AA96 (UniProtKB/TrEMBL)
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2012-09-11
Card11
caspase recruitment domain family, member 11
LOC100363332
caspase recruitment domain family, member 11
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2010-05-06
LOC100363332
caspase recruitment domain family, member 11
Symbol and Name status set to provisional
70820 PROVISIONAL
