CARD11 (caspase recruitment domain family member 11) - Rat Genome Database

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Gene: CARD11 (caspase recruitment domain family member 11) Sus scrofa
Analyze
Symbol: CARD11
Name: caspase recruitment domain family member 11
RGD ID: 13845129
Description: ENCODES a protein that exhibits CARD domain binding (inferred); obsolete protein self-association (inferred); INVOLVED IN B cell differentiation (ortholog); B cell proliferation (ortholog); CD4-positive, alpha-beta T cell proliferation (ortholog); ASSOCIATED WITH adult T-cell leukemia/lymphoma (ortholog); asthma (ortholog); atopic dermatitis (ortholog); FOUND IN CBM complex (inferred); cytoplasm (inferred); immunological synapse (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: caspase recruitment domain-containing protein 11
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl32,145,178 - 2,266,355 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.132,145,178 - 2,266,377 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CARD11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl32,145,178 - 2,266,355 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.132,145,178 - 2,266,377 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CARD11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3872,906,142 - 3,043,867 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl72,906,142 - 3,044,228 (-)EnsemblGRCh38hg38GRCh38
GRCh3772,945,776 - 3,083,501 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3672,912,295 - 3,050,105 (-)NCBINCBI36Build 36hg18NCBI36
Build 3472,719,023 - 2,856,711NCBI
Celera72,914,379 - 3,052,190 (-)NCBICelera
Cytogenetic Map7p22.2NCBI
HuRef72,863,784 - 3,002,087 (-)NCBIHuRef
CHM1_172,945,368 - 3,083,717 (-)NCBICHM1_1
T2T-CHM13v2.073,019,747 - 3,157,416 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v272,993,579 - 3,131,390 (-)NCBI
Card11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395140,858,109 - 140,986,398 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5140,858,745 - 140,986,337 (-)EnsemblGRCm39 Ensembl
GRCm385140,872,999 - 141,000,596 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5140,872,990 - 141,000,582 (-)EnsemblGRCm38mm10GRCm38
MGSCv375141,348,953 - 141,476,550 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365141,125,473 - 141,252,966 (-)NCBIMGSCv36mm8
Celera5137,928,048 - 138,050,352 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map579.42NCBI
Card11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81218,735,088 - 18,872,045 (+)NCBIGRCr8
mRatBN7.21213,621,140 - 13,758,115 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1213,621,087 - 13,758,112 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01215,700,600 - 15,844,512 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1215,700,825 - 15,844,512 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01217,780,109 - 17,843,748 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41214,165,040 - 14,229,267 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1215,382,300 - 15,519,160 (+)NCBICelera
Cytogenetic Map12q11NCBI
Card11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546012,368,918 - 12,490,041 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546012,368,987 - 12,487,675 (+)NCBIChiLan1.0ChiLan1.0
CARD11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v267,863,477 - 8,001,993 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1756,188,181 - 56,326,694 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v073,166,788 - 3,304,729 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.173,258,736 - 3,395,626 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl73,258,736 - 3,332,999 (-)Ensemblpanpan1.1panPan2
CARD11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1614,273,115 - 14,331,029 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl614,210,114 - 14,332,094 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha615,666,400 - 15,792,761 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0614,329,524 - 14,455,900 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl614,335,283 - 14,455,892 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1614,134,984 - 14,261,297 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0614,061,830 - 14,188,602 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0614,347,905 - 14,474,301 (+)NCBIUU_Cfam_GSD_1.0
Card11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344142,360,008 - 142,471,017 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936823581,955 - 621,208 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936823580,438 - 621,298 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC103246958
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12818,657,941 - 18,714,202 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660903,151,200 - 3,325,501 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Card11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474029,974,689 - 30,085,981 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474029,974,707 - 30,085,498 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CARD11
3659 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 2 4
Low 9 1 1 1 10 3 3
Below cutoff 1 1 3 12 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000062181   ⟹   ENSSSCP00000038456
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl32,145,178 - 2,266,355 (-)Ensembl
RefSeq Acc Id: XM_021086015   ⟹   XP_020941674
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.132,145,178 - 2,266,377 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021086016   ⟹   XP_020941675
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.132,145,178 - 2,207,244 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021086018   ⟹   XP_020941677
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.132,145,178 - 2,266,377 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021086019   ⟹   XP_020941678
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.132,145,178 - 2,207,245 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020941677   ⟸   XM_021086018
- Peptide Label: isoform X2
- UniProtKB: A0A4X1TJ35 (UniProtKB/TrEMBL),   A0A8D0Z304 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020941674   ⟸   XM_021086015
- Peptide Label: isoform X1
- UniProtKB: A0A8D0UPF8 (UniProtKB/TrEMBL),   A0A287A3X6 (UniProtKB/TrEMBL),   A0A8D0Z304 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020941678   ⟸   XM_021086019
- Peptide Label: isoform X2
- UniProtKB: A0A4X1TJ35 (UniProtKB/TrEMBL),   A0A8D0Z304 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020941675   ⟸   XM_021086016
- Peptide Label: isoform X1
- UniProtKB: A0A8D0UPF8 (UniProtKB/TrEMBL),   A0A287A3X6 (UniProtKB/TrEMBL),   A0A8D0Z304 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000038456   ⟸   ENSSSCT00000062181
Protein Domains
CARD


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000034390 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015047799 UniProtKB/TrEMBL
  ENSSSCG00025034149 UniProtKB/TrEMBL
  ENSSSCG00035021072 UniProtKB/TrEMBL
  ENSSSCG00040014532 UniProtKB/TrEMBL
  ENSSSCG00045018842 UniProtKB/TrEMBL
  ENSSSCG00050000210 UniProtKB/TrEMBL
  ENSSSCG00055027899 UniProtKB/TrEMBL
  ENSSSCG00060027382 UniProtKB/TrEMBL
  ENSSSCG00070010359 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000062181 ENTREZGENE
  ENSSSCT00000062181.3 UniProtKB/TrEMBL
  ENSSSCT00015063664.1 UniProtKB/TrEMBL
  ENSSSCT00015063722.1 UniProtKB/TrEMBL
  ENSSSCT00015064214.1 UniProtKB/TrEMBL
  ENSSSCT00025046559.1 UniProtKB/TrEMBL
  ENSSSCT00025046668.1 UniProtKB/TrEMBL
  ENSSSCT00035027447.1 UniProtKB/TrEMBL
  ENSSSCT00035027451.1 UniProtKB/TrEMBL
  ENSSSCT00040019458.1 UniProtKB/TrEMBL
  ENSSSCT00045032091.1 UniProtKB/TrEMBL
  ENSSSCT00045032228.1 UniProtKB/TrEMBL
  ENSSSCT00050000232.1 UniProtKB/TrEMBL
  ENSSSCT00050000240.1 UniProtKB/TrEMBL
  ENSSSCT00055055232.1 UniProtKB/TrEMBL
  ENSSSCT00055055328.1 UniProtKB/TrEMBL
  ENSSSCT00060037056.1 UniProtKB/TrEMBL
  ENSSSCT00060037062.1 UniProtKB/TrEMBL
  ENSSSCT00070020173.1 UniProtKB/TrEMBL
  ENSSSCT00070020178.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.533.10 UniProtKB/TrEMBL
  2.30.42.10 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro CARD UniProtKB/TrEMBL
  CARD_CARD11 UniProtKB/TrEMBL
  DEATH-like_dom_sf UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
NCBI Gene CARD11 ENTREZGENE
PANTHER CASPASE RECRUITMENT DOMAIN FAMILY UniProtKB/TrEMBL
  PTHR14559:SF4 UniProtKB/TrEMBL
Pfam CARD UniProtKB/TrEMBL
PROSITE CARD UniProtKB/TrEMBL
Superfamily-SCOP SSF47986 UniProtKB/TrEMBL
  SSF50156 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A287A3X6 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TJ35 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TJ39_PIG UniProtKB/TrEMBL
  A0A8D0UPF8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0Z304 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0Z654_PIG UniProtKB/TrEMBL
  A0A8D1UCS9_PIG UniProtKB/TrEMBL
VGNC ID VGNC:86186 ENTREZGENE