PPP1R9B (protein phosphatase 1 regulatory subunit 9B) - Rat Genome Database

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Gene: PPP1R9B (protein phosphatase 1 regulatory subunit 9B) Canis lupus familiaris
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Symbol: PPP1R9B
Name: protein phosphatase 1 regulatory subunit 9B
RGD ID: 12237755
Description: ENCODES a protein that exhibits actin binding (ortholog); actin filament binding (ortholog); D2 dopamine receptor binding (ortholog); INVOLVED IN actin filament depolymerization (ortholog); actin filament organization (ortholog); calcium-mediated signaling (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); Cognitive Dysfunction (ortholog); Colorectal Neoplasms (ortholog); FOUND IN actin cytoskeleton (ortholog); cytoplasmic side of dendritic spine plasma membrane (ortholog); dendritic spine (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: neurabin-2; protein phosphatase 1, regulatory (inhibitor) subunit 9B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1926,135,982 - 26,152,303 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl926,137,464 - 26,151,810 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha925,529,124 - 25,544,951 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0926,930,469 - 26,946,307 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl926,930,469 - 26,946,307 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1925,698,261 - 25,714,094 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0925,956,940 - 25,972,777 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0926,086,858 - 26,102,695 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin filament depolymerization  (ISO)
actin filament organization  (IBA,IEA,ISO)
calcium-mediated signaling  (IBA,IEA,ISO)
cell differentiation  (IEA)
cell migration  (IEA)
cellular response to epidermal growth factor stimulus  (ISO)
cellular response to estradiol stimulus  (ISO)
cellular response to morphine  (IEA)
cellular response to peptide  (ISO)
cellular response to xenobiotic stimulus  (ISO)
cerebral cortex development  (ISO)
dendrite development  (IEA,ISO)
developmental process involved in reproduction  (ISO)
filopodium assembly  (IEA)
hippocampus development  (ISO)
learning  (ISO)
male mating behavior  (ISO)
negative regulation of cell growth  (IEA)
nervous system development  (IEA)
neuron projection development  (IBA)
positive regulation of protein localization  (ISO)
positive regulation of protein localization to actin cortical patch  (ISO)
positive regulation of protein localization to plasma membrane  (ISO)
protein localization to actin cytoskeleton  (ISO)
protein localization to cell periphery  (ISO)
regulation of opioid receptor signaling pathway  (IEA)
regulation of postsynapse assembly  (IEA)
regulation of protein phosphorylation  (ISO)
reproductive system development  (ISO)
response to amino acid  (ISO)
response to amphetamine  (ISO)
response to estradiol  (ISO)
response to immobilization stress  (ISO)
response to kainic acid  (ISO)
response to L-phenylalanine derivative  (ISO)
response to nicotine  (ISO)
response to prostaglandin E  (ISO)
response to steroid hormone  (ISO)
response to xenobiotic stimulus  (ISO)

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
PPP1R9B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1926,135,982 - 26,152,303 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl926,137,464 - 26,151,810 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha925,529,124 - 25,544,951 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0926,930,469 - 26,946,307 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl926,930,469 - 26,946,307 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1925,698,261 - 25,714,094 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0925,956,940 - 25,972,777 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0926,086,858 - 26,102,695 (-)NCBIUU_Cfam_GSD_1.0
PPP1R9B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381750,133,737 - 50,150,677 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1750,133,737 - 50,150,677 (-)EnsemblGRCh38hg38GRCh38
GRCh371748,211,101 - 48,228,038 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361745,566,100 - 45,582,876 (-)NCBINCBI36Build 36hg18NCBI36
Build 341745,567,694 - 45,582,873NCBI
Celera1744,671,218 - 44,687,998 (-)NCBICelera
Cytogenetic Map17q21.33NCBI
HuRef1743,578,978 - 43,595,756 (-)NCBIHuRef
CHM1_11748,275,419 - 48,292,198 (-)NCBICHM1_1
T2T-CHM13v2.01751,000,814 - 51,017,737 (-)NCBIT2T-CHM13v2.0
Ppp1r9b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391194,882,038 - 94,897,724 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1194,881,861 - 94,897,725 (+)EnsemblGRCm39 Ensembl
GRCm381194,991,212 - 95,006,898 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1194,991,035 - 95,006,899 (+)EnsemblGRCm38mm10GRCm38
MGSCv371194,852,526 - 94,868,212 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361194,807,302 - 94,822,974 (+)NCBIMGSCv36mm8
Celera11104,604,585 - 104,620,251 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1159.01NCBI
Ppp1r9b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81080,434,888 - 80,450,919 (+)NCBIGRCr8
mRatBN7.21079,938,055 - 79,954,085 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1079,938,066 - 79,954,083 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1084,887,200 - 84,903,206 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01084,385,269 - 84,401,276 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01079,778,362 - 79,794,325 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01082,800,704 - 82,816,735 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1082,800,704 - 82,816,731 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01082,616,223 - 82,632,356 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41083,674,797 - 83,690,639 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11083,689,166 - 83,705,009 (+)NCBI
Celera1078,712,214 - 78,727,757 (+)NCBICelera
Cytogenetic Map10q26NCBI
Ppp1r9b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545111,516,548 - 11,530,830 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545111,516,548 - 11,530,263 (+)NCBIChiLan1.0ChiLan1.0
PPP1R9B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21966,322,412 - 66,339,660 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11771,128,896 - 71,146,153 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01744,224,007 - 44,240,906 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11749,098,089 - 49,129,659 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1749,098,089 - 49,126,932 (-)Ensemblpanpan1.1panPan2
Ppp1r9b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560225,560,948 - 25,577,086 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493649011,497,389 - 11,514,191 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPP1R9B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1226,319,124 - 26,336,562 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11226,319,123 - 26,337,089 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21226,358,245 - 26,375,863 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PPP1R9B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11643,188,400 - 43,205,621 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1643,188,022 - 43,205,680 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607713,904,402 - 13,921,606 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppp1r9b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247956,124,159 - 6,137,955 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247956,124,273 - 6,137,776 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PPP1R9B
139 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000026939   ⟹   ENSCAFP00000025042
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl926,137,464 - 26,151,810 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000068468   ⟹   ENSCAFP00000053373
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl926,137,464 - 26,151,810 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000077557   ⟹   ENSCAFP00000065605
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl926,137,464 - 26,151,810 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845021782   ⟹   ENSCAFP00845017133
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl926,930,469 - 26,946,307 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845021834   ⟹   ENSCAFP00845017174
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl926,931,644 - 26,946,307 (-)Ensembl
RefSeq Acc Id: XM_038485873   ⟹   XP_038341801
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1925,698,261 - 25,714,094 (-)NCBI
RefSeq Acc Id: XM_038547633   ⟹   XP_038403561
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0926,086,858 - 26,102,695 (-)NCBI
RefSeq Acc Id: XM_038611633   ⟹   XP_038467561
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0925,956,940 - 25,972,777 (-)NCBI
RefSeq Acc Id: XM_038676830   ⟹   XP_038532758
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0926,930,469 - 26,946,307 (-)NCBI
RefSeq Acc Id: XM_548196   ⟹   XP_548196
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1926,135,982 - 26,152,303 (-)NCBI
Dog10K_Boxer_Tasha925,529,124 - 25,544,951 (-)NCBI
Sequence:
RefSeq Acc Id: XP_548196   ⟸   XM_548196
- UniProtKB: A0A8P0PE40 (UniProtKB/TrEMBL),   A0A8P0NID1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000065605   ⟸   ENSCAFT00000077557
Ensembl Acc Id: ENSCAFP00000053373   ⟸   ENSCAFT00000068468
Ensembl Acc Id: ENSCAFP00000025042   ⟸   ENSCAFT00000026939
RefSeq Acc Id: XP_038341801   ⟸   XM_038485873
RefSeq Acc Id: XP_038467561   ⟸   XM_038611633
RefSeq Acc Id: XP_038532758   ⟸   XM_038676830
- UniProtKB: A0A8I3NG50 (UniProtKB/TrEMBL),   A0A8I3NLG2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038403561   ⟸   XM_038547633
- UniProtKB: A0A8I3NLG2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845017174   ⟸   ENSCAFT00845021834
Ensembl Acc Id: ENSCAFP00845017133   ⟸   ENSCAFT00845021782
Protein Domains
PDZ


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000017004 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00845012234 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000026939.6 UniProtKB/TrEMBL
  ENSCAFT00000077557.2 UniProtKB/TrEMBL
  ENSCAFT00845021782 ENTREZGENE
  ENSCAFT00845021782.1 UniProtKB/TrEMBL
  ENSCAFT00845021834.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.42.10 UniProtKB/TrEMBL
InterPro Neurabin-1/2_PDZ UniProtKB/TrEMBL
  Neurabin-like UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
KEGG Report cfa:491076 UniProtKB/TrEMBL
NCBI Gene PPP1R9B ENTREZGENE
PANTHER PTHR16154 UniProtKB/TrEMBL
  PTHR16154:SF24 UniProtKB/TrEMBL
Pfam PDZ UniProtKB/TrEMBL
  PDZ_5 UniProtKB/TrEMBL
PROSITE PDZ UniProtKB/TrEMBL
SMART PDZ UniProtKB/TrEMBL
Superfamily-SCOP SSF50156 UniProtKB/TrEMBL
UniProt A0A8I3NG50 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NLG2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0NID1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0PE40 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:44903 ENTREZGENE