Symbol:
CHRNA7
Name:
cholinergic receptor nicotinic alpha 7 subunit
RGD ID:
12225176
Description:
ENCODES a protein that exhibits acetylcholine binding (ortholog); acetylcholine-gated monoatomic cation-selective channel activity (ortholog); adenylate cyclase binding (ortholog); INVOLVED IN activation of protein kinase C activity (ortholog); calcium ion transport (ortholog); cognition (ortholog); PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; ASSOCIATED WITH Alzheimer's disease (ortholog); attention deficit hyperactivity disorder (ortholog); Auditory Perceptual Disorders (ortholog); FOUND IN acetylcholine-gated channel complex (ortholog); asymmetric synapse (ortholog); axon (ortholog)
Type:
protein-coding
RefSeq Status:
MODEL
Previously known as:
neuronal acetylcholine receptor subunit alpha-7
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
CHRNA7 (cholinergic receptor nicotinic alpha 7 subunit) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):
Chrna7 (cholinergic receptor, nicotinic, alpha polypeptide 7) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):
Chrna7 (cholinergic receptor nicotinic alpha 7 subunit) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Chrna7 (cholinergic receptor nicotinic alpha 7 subunit) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
LOC100977072 (neuronal acetylcholine receptor subunit alpha-7) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Chrna7 (cholinergic receptor nicotinic alpha 7 subunit) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
CHRNA7 (cholinergic receptor nicotinic alpha 7 subunit) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
CHRNA7 (cholinergic receptor nicotinic alpha 7 subunit) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Chrna7 (cholinergic receptor nicotinic alpha 7 subunit) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Latest Assembly:
CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 3 36,852,082 - 37,164,930 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 3 36,852,543 - 36,978,399 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 3 39,517,659 - 39,644,156 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 3 37,232,973 - 37,359,572 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 3 37,231,040 - 37,360,220 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 3 36,756,424 - 36,882,829 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 3 37,011,929 - 37,138,401 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 3 37,222,873 - 37,349,426 (-) NCBI UU_Cfam_GSD_1.0
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Biological Process
acetylcholine receptor signaling pathway (IEA) activation of protein kinase C activity (ISO) associative learning (IEA) B cell activation (IEA) behavioral response to ethanol (IEA) behavioral response to nicotine (IEA) calcium ion transport (ISO) chemical synaptic transmission (IBA) cognition (ISO) dendrite arborization (IEA) dendritic spine organization (IEA) dopamine biosynthetic process (ISO) endocytosis (IEA) establishment of localization in cell (IEA) excitatory postsynaptic potential (IEA) flagellated sperm motility (IEA) generation of ovulation cycle rhythm (IEA) intracellular calcium ion homeostasis (ISO) learning or memory (IEA,ISO) ligand-gated ion channel signaling pathway (ISO) memory (IEA,ISO) modulation of chemical synaptic transmission (IEA) modulation of excitatory postsynaptic potential (IEA) monoatomic ion transmembrane transport (IBA,IEA,ISO) monoatomic ion transport (IEA) negative regulation of amyloid-beta formation (ISO) negative regulation of canonical NF-kappaB signal transduction (IEA) negative regulation of cytokine production involved in inflammatory response (IEA) negative regulation of ERK1 and ERK2 cascade (ISO) negative regulation of inflammatory response (IEA) negative regulation of interleukin-1 beta production (IEA) negative regulation of interleukin-6 production (IEA) negative regulation of tumor necrosis factor production (IEA,ISO) neuronal action potential (ISO) ovulation cycle (IEA) positive regulation of amyloid-beta formation (IEA) positive regulation of angiogenesis (ISO) positive regulation of cell population proliferation (ISO) positive regulation of ERK1 and ERK2 cascade (IEA) positive regulation of excitatory postsynaptic potential (IEA) positive regulation of gene expression (ISO) positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure (IEA) positive regulation of long-term synaptic potentiation (IEA) positive regulation of MAPK cascade (ISO) positive regulation of protein metabolic process (IEA) presynaptic modulation of chemical synaptic transmission (ISO) regulation of amyloid fibril formation (IEA) regulation of amyloid precursor protein catabolic process (ISO) regulation of inflammatory response (IEA) regulation of membrane potential (IBA,IEA) regulation of norepinephrine secretion (IEA) regulation of postsynaptic membrane potential (IEA) regulation of response to drug (ISO) regulation of synapse structural plasticity (IEA) regulation of synaptic transmission, dopaminergic (IEA) response to acetylcholine (ISO) response to amyloid-beta (IEA) response to carbamate (ISO) response to cold (IEA) response to ethanol (IEA,ISO) response to food (IEA) response to hypoxia (ISO) response to nicotine (IEA,ISO) sensory processing (IEA) signal transduction (ISO) synapse organization (IEA) synaptic transmission involved in micturition (ISO) synaptic transmission, cholinergic (IEA,ISO) T cell activation (IEA)
CHRNA7 Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 3 36,852,082 - 37,164,930 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 3 36,852,543 - 36,978,399 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 3 39,517,659 - 39,644,156 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 3 37,232,973 - 37,359,572 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 3 37,231,040 - 37,360,220 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 3 36,756,424 - 36,882,829 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 3 37,011,929 - 37,138,401 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 3 37,222,873 - 37,349,426 (-) NCBI UU_Cfam_GSD_1.0
CHRNA7 Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 15 32,030,483 - 32,173,018 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 15 31,923,438 - 32,173,018 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 15 32,322,686 - 32,465,219 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 15 30,110,018 - 30,248,541 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 15 30,110,017 - 30,248,525 NCBI Celera 15 8,162,865 - 8,292,202 (-) NCBI Celera Cytogenetic Map 15 q13.3 NCBI HuRef 15 9,499,328 - 9,603,273 (+) NCBI HuRef CHM1_1 15 32,312,897 - 32,452,812 (+) NCBI CHM1_1 T2T-CHM13v2.0 15 29,824,630 - 29,967,342 (+) NCBI T2T-CHM13v2.0
Chrna7 Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 7 62,748,440 - 62,862,274 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 7 62,748,440 - 62,862,317 (-) Ensembl GRCm39 Ensembl GRCm38 7 63,098,692 - 63,212,526 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 7 63,098,692 - 63,212,569 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 7 70,243,578 - 70,357,412 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 7 62,977,642 - 63,091,468 (-) NCBI MGSCv36 mm8 Celera 7 60,542,827 - 60,660,378 (-) NCBI Celera Cytogenetic Map 7 C NCBI cM Map 7 34.47 NCBI
Chrna7 Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 1 126,123,425 - 126,249,181 (-) NCBI GRCr8 mRatBN7.2 1 116,711,559 - 116,837,269 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 1 116,714,711 - 116,837,240 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 1 124,676,761 - 124,793,917 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 1 131,859,276 - 131,976,435 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 1 124,684,982 - 124,802,138 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 1 123,897,341 - 124,039,263 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 1 123,899,657 - 124,039,196 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 1 125,029,451 - 125,158,153 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 1 117,587,580 - 117,716,267 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 1 117,665,347 - 117,794,621 (-) NCBI Celera 1 108,976,664 - 109,097,764 (-) NCBI Celera Cytogenetic Map 1 q22 NCBI
Chrna7 Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955416 30,687,478 - 30,798,700 (+) Ensembl ChiLan1.0 ChiLan1.0 NW_004955416 30,687,518 - 30,798,700 (+) NCBI ChiLan1.0 ChiLan1.0
LOC100977072 Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 16 20,841,679 - 20,981,068 (+) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 15 25,565,746 - 25,705,121 (+) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 15 10,525,535 - 10,667,227 (+) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 15 29,565,885 - 29,705,194 (+) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 15 29,565,885 - 29,705,194 (+) Ensembl panpan1.1 panPan2
Chrna7
CHRNA7 Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 1 142,803,701 - 142,937,123 (-) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 1 142,803,697 - 142,937,124 (-) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 1 158,717,002 - 158,849,994 (-) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
CHRNA7 Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 26 50,554,143 - 50,686,847 (-) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 26 50,551,829 - 50,686,803 (-) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666048 90,139,706 - 90,283,400 (+) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Chrna7
.
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
6
5
5
23
22
16
6
6
6
6
33
22
12
14
10
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENSCAFT00000016296 ⟹ ENSCAFP00000015074
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source CanFam3.1 Ensembl 3 36,852,543 - 36,977,748 (-) Ensembl
Ensembl Acc Id:
ENSCAFT00000068553 ⟹ ENSCAFP00000049023
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source CanFam3.1 Ensembl 3 36,852,543 - 36,978,399 (-) Ensembl
Ensembl Acc Id:
ENSCAFT00000071562 ⟹ ENSCAFP00000053234
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source CanFam3.1 Ensembl 3 36,852,543 - 36,978,399 (-) Ensembl
Ensembl Acc Id:
ENSCAFT00000082455 ⟹ ENSCAFP00000066225
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source CanFam3.1 Ensembl 3 36,852,543 - 36,978,399 (-) Ensembl
Ensembl Acc Id:
ENSCAFT00845035011 ⟹ ENSCAFP00845027416
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source ROS_Cfam_1.0 Ensembl 3 37,231,040 - 37,360,220 (-) Ensembl
Ensembl Acc Id:
ENSCAFT00845035115 ⟹ ENSCAFP00845027486
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source ROS_Cfam_1.0 Ensembl 3 37,231,040 - 37,360,220 (-) Ensembl
RefSeq Acc Id:
XM_022416819 ⟹ XP_022272527
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source CanFam3.1 3 36,852,082 - 36,977,882 (-) NCBI Dog10K_Boxer_Tasha 3 39,517,659 - 39,644,156 (-) NCBI
Sequence:
GGAGGCGGGGGCGCGCGCTCGGCTCTTTAAAGGCGCGCCAGCCCCGCCGGGAAGGCGGCTCCGCGGCCACAGGCGCAGGCCCGGGCCGAGCAGGAGACGCGGGGCGCGGCGGCCGCGGTAGCTCCGAG
hide sequence
RefSeq Acc Id:
XM_038471672 ⟹ XP_038327600
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source UMICH_Zoey_3.1 3 36,756,424 - 36,882,829 (-) NCBI
RefSeq Acc Id:
XM_038532597 ⟹ XP_038388525
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source UU_Cfam_GSD_1.0 3 37,222,873 - 37,349,426 (-) NCBI
RefSeq Acc Id:
XM_038532598 ⟹ XP_038388526
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source UU_Cfam_GSD_1.0 3 37,222,873 - 37,349,426 (-) NCBI
RefSeq Acc Id:
XM_038596903 ⟹ XP_038452831
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source UNSW_CanFamBas_1.0 3 37,011,929 - 37,138,401 (-) NCBI
RefSeq Acc Id:
XM_038596904 ⟹ XP_038452832
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source UNSW_CanFamBas_1.0 3 37,011,929 - 37,138,401 (-) NCBI
RefSeq Acc Id:
XM_038661110 ⟹ XP_038517038
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source ROS_Cfam_1.0 3 37,232,973 - 37,359,572 (-) NCBI
RefSeq Acc Id:
XM_038661111 ⟹ XP_038517039
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source ROS_Cfam_1.0 3 37,232,973 - 37,359,572 (-) NCBI
RefSeq Acc Id:
XM_545813 ⟹ XP_545813
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source CanFam3.1 3 36,852,082 - 36,977,889 (-) NCBI Dog10K_Boxer_Tasha 3 39,517,659 - 39,644,156 (-) NCBI
Sequence:
AGCGCGCGGAGGCGGGGGCGCGCGCTCGGCTCTTTAAAGGCGCGCCAGCCCCGCCGGGAAGGCGGCTCCGCGGCCACAGGCGCAGGCCCGGGCCGAGCAGGAGACGCGGGGCGCGGCGGCCGCGGTAG
hide sequence
RefSeq Acc Id:
XP_545813 ⟸ XM_545813
- Peptide Label:
isoform X1
- UniProtKB:
A0A8P0NCK2 (UniProtKB/TrEMBL), A0A8C0S3B3 (UniProtKB/TrEMBL)
- Sequence:
MRRPMWLALAASLLHVSLQGEFQRKLYKELVKNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNMSEYPGVKTVRFPDGLIWKPDILLYNSADERFDATFHTNVL
hide sequence
RefSeq Acc Id:
XP_022272527 ⟸ XM_022416819
- Peptide Label:
isoform X2
- Sequence:
MTRNRSLCTSPSASCRSWTCADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQQCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVAFNKLHGCLCDIPIKINKQGNFIQTC
hide sequence
Ensembl Acc Id:
ENSCAFP00000049023 ⟸ ENSCAFT00000068553
Ensembl Acc Id:
ENSCAFP00000066225 ⟸ ENSCAFT00000082455
Ensembl Acc Id:
ENSCAFP00000015074 ⟸ ENSCAFT00000016296
Ensembl Acc Id:
ENSCAFP00000053234 ⟸ ENSCAFT00000071562
RefSeq Acc Id:
XP_038327600 ⟸ XM_038471672
- Peptide Label:
isoform X1
RefSeq Acc Id:
XP_038452832 ⟸ XM_038596904
- Peptide Label:
isoform X2
RefSeq Acc Id:
XP_038452831 ⟸ XM_038596903
- Peptide Label:
isoform X1
RefSeq Acc Id:
XP_038517039 ⟸ XM_038661111
- Peptide Label:
isoform X2
RefSeq Acc Id:
XP_038517038 ⟸ XM_038661110
- Peptide Label:
isoform X1
- UniProtKB:
A0A8C0S3B3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038388526 ⟸ XM_038532598
- Peptide Label:
isoform X2
RefSeq Acc Id:
XP_038388525 ⟸ XM_038532597
- Peptide Label:
isoform X1
- UniProtKB:
A0A8C0S3B3 (UniProtKB/TrEMBL)
Ensembl Acc Id:
ENSCAFP00845027416 ⟸ ENSCAFT00845035011
Ensembl Acc Id:
ENSCAFP00845027486 ⟸ ENSCAFT00845035115
