RGD:82681432 Rat Genome Database

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Variant: RGD:82681432 -  Canis lupus familiaris

RGD ID: 82681432
Genic Status: GENIC
Type: SNV (SO:0001483) 
Associated Genes: CHRNA7  
Reference Nucleotide: C
Variant Nucleotide: T
Position
Assembly Chr Position
CanFam3.1 3 36,852,730
JBrowse: View Region in Genome Browser (JBrowse)
Model
Breeds: Chinese indigenous dogs




Gene Symbol:CHRNA7
Accession:XM_022416819
Location:EXON
Amino Acid Prediction: R to Q (nonsynonymous)
Amino Acid Position: 378
Polyphen Predictions
Prediction Basis Effect Site Score1 Score2 Diff Number Observed Structures Protein ID PDB ID Inverted
possibly damaging alignment     -1.421 -2.462 +1.041 191   XP_022272527   -
Amino Acid Sequence
(Calculated using NCBI transcript definition)
MTRNRSLCTSPSASCRSWTCADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQQCKLKFGSWSYGGWS
LDLQMQEADISGYIPNGEWDLVAFNKLHGCLCDIPIKINKQGNFIQTCFLSPATHGGIPGKRSEKFYECCKEPYPDVTFT
VTIRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMII
VGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAGPPTTNGN
LLYIGFRGLDGVHCAPTPDSGVVCGRMACSPTHDEHLLHGGQPSEGDPDLAKILEEIQYIANRFRCQDESDAICSEWKFA
ACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA*

Gene Symbol:CHRNA7
Accession:XM_545813
Location:EXON
Amino Acid Prediction: R to Q (nonsynonymous)
Amino Acid Position: 438
Polyphen Predictions
Prediction Basis Effect Site Score1 Score2 Diff Number Observed Structures Protein ID PDB ID Inverted
benign alignment     -1.860 -1.978 +0.118 549   XP_545813   -
Amino Acid Sequence
(Calculated using NCBI transcript definition)
MRRPMWLALAASLLHVSLQGEFQRKLYKELVKNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWT
DHYLQWNMSEYPGVKTVRFPDGLIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQQ
CKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGIPGKRSEKFYECCKEPYPDVTFTVTIRRRTLYYGLNLLIPCVL
ISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPD
GGKMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAGPPTTNGNLLYIGFRGLDGVHCAPTPDS
GVVCGRMACSPTHDEHLLHGGQPSEGDPDLAKILEEIQYIANRFRCQDESDAICSEWKFAACVVDRLCLMAFSVFTIICT
IGILMSAPNFVEAVSKDFA*
Chinese indigenous dogs (LJ7)