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Gene: TH (tyrosine hydroxylase) Pan paniscus

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Symbol:

Name:

tyrosine hydroxylase

RGD ID:

11825877

Description:

ENCODES a protein that exhibits amino acid binding (ortholog); dopamine binding (ortholog); ferric iron binding (ortholog); INVOLVED IN aminergic neurotransmitter loading into synaptic vesicle (ortholog); catecholamine biosynthetic process (ortholog); cellular response to alkaloid (ortholog); PARTICIPATES IN aromatic L-amino acid decarboxylase deficiency pathway; catecholamine biosynthetic pathway; dopamine biosynthetic pathway; ASSOCIATED WITH Beckwith-Wiedemann syndrome (ortholog); brain disease (ortholog); Brain Injuries (ortholog); FOUND IN axon (ortholog); cytoplasmic vesicle membrane (ortholog); dendrite (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

tyrosine 3-monooxygenase

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TH (tyrosine hydroxylase)	NCBI	Ortholog
Mus musculus (house mouse):	Th (tyrosine hydroxylase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Th (tyrosine hydroxylase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Th (tyrosine hydroxylase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TH (tyrosine hydroxylase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Th (tyrosine hydroxylase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TH (tyrosine hydroxylase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TH (tyrosine hydroxylase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Th (tyrosine hydroxylase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	4,590,095 - 4,597,992 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	3,801,867 - 3,809,764 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	2,204,820 - 2,212,750 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	2,234,095 - 2,242,030 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	2,231,248 - 2,242,433 (-)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TH	Bonobo	Brain Injuries		ISO	Th (Rattus norvegicus)	9068941	protein:decreased activity:striatum (rat)	RGD	PMID:21047500 and REF_RGD_ID:5128822
TH	Bonobo	brain ischemia		ISO	Th (Rattus norvegicus)	9068941	protein:decreased expression:solitary tract nucleus more ...	RGD	PMID:18356740 and REF_RGD_ID:5129691
TH	Bonobo	congestive heart failure		ISO	Th (Rattus norvegicus)	9068941	protein:increased expression:paraventricular thalamic nucleus (rat)	RGD	PMID:21287352 and REF_RGD_ID:5128674
TH	Bonobo	congestive heart failure		ISO	Th (Mus musculus)	9068941		RGD	PMID:7715703 and REF_RGD_ID:737737
TH	Bonobo	Contusions		ISO	Th (Rattus norvegicus)	9068941	mRNA:increased expression:adrenal gland (rat)	RGD	PMID:18987458 and REF_RGD_ID:5129532
TH	Bonobo	depressive disorder		ISO	Th (Rattus norvegicus)	9068941	mRNA and protein:decreased expression:hippocampus:	RGD	PMID:24495952 and REF_RGD_ID:9681459
TH	Bonobo	epilepsy		ISO	Th (Rattus norvegicus)	9068941	protein:decreased activity:cerebral cortex (rat)	RGD	PMID:19605093 and REF_RGD_ID:5128800
TH	Bonobo	Experimental Diabetes Mellitus		ISO	Th (Rattus norvegicus)	9068941	protein:increased expression:seminal vesicle	RGD	PMID:17151307 and REF_RGD_ID:1601629
TH	Bonobo	Experimental Liver Cirrhosis		ISO	Th (Rattus norvegicus)	9068941	mRNA:decreased expression:superior mesenteric artery (rat)	RGD	PMID:18457899 and REF_RGD_ID:5129683
TH	Bonobo	heroin dependence	onset	ISO	TH (Homo sapiens)	9068941	DNA:SNP:5'utr:(rs10770140) (human)	RGD	PMID:32736537 and REF_RGD_ID:405866368
TH	Bonobo	hyperprolactinemia		ISO	Th (Rattus norvegicus)	9068941	protein:increased tyrosine nitration:hypothalamus and median eminence (rat)	RGD	PMID:21178126 and REF_RGD_ID:5128768
TH	Bonobo	hyperprolactinemia	treatment	ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:26297122 and REF_RGD_ID:13506955
TH	Bonobo	hypertension	susceptibility	ISO	TH (Homo sapiens)	9068941	DNA:polymorphism:intron:g.1090T>C rs2070762 (human)	RGD	PMID:16636198 and REF_RGD_ID:1601631
TH	Bonobo	hypertension		ISO	Th (Rattus norvegicus)	9068941	mRNA:increased expression:brain	RGD	PMID:16650497 and REF_RGD_ID:1601630
TH	Bonobo	hypoglycemia		ISO	Th (Rattus norvegicus)	9068941	associated with Diabetes Mellitus more ...	RGD	PMID:16396986 and REF_RGD_ID:5130724
TH	Bonobo	intellectual disability		ISO	Th (Mus musculus)	9068941	protein:increased serine phosphorylation:cerebral cortex (mouse)	RGD	PMID:18823370 and REF_RGD_ID:2311578
TH	Bonobo	Machado-Joseph disease		ISO	Th (Rattus norvegicus)	9068941	protein:decreased expression:substantia nigra (rat)	RGD	PMID:18385100 and REF_RGD_ID:5131159
TH	Bonobo	middle cerebral artery infarction		ISO	Th (Rattus norvegicus)	9068941	protein:decreased expression:substantia nigra pars compacta and neuron (rat)	RGD	PMID:21366664 and REF_RGD_ID:5128609
TH	Bonobo	myocardial infarction	no_association	ISO	TH (Homo sapiens)	9068941	DNA:polymorphism:intron:g.1170_1173dupTCAT (human)	RGD	PMID:16139102 and REF_RGD_ID:1580048
TH	Bonobo	obesity	resistance	ISO	TH (Homo sapiens)	9068941	DNA:polymorphism:intron:g.1170_1173dupTCAT (human)	RGD	PMID:16251897 and REF_RGD_ID:1601632
TH	Bonobo	Parkinson's disease		ISO	TH (Homo sapiens)	9068941	human gene in a rat model	RGD	PMID:9853519 and REF_RGD_ID:5129121
TH	Bonobo	Parkinson's disease		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:2573072 and REF_RGD_ID:5129120
TH	Bonobo	Parkinson's disease		ISO	Th (Rattus norvegicus)	9068941	protein:decreased expression:midbrain and neuron (rat)	RGD	PMID:21376343 and REF_RGD_ID:5128607
TH	Bonobo	Parkinson's disease		ISO	TH (Homo sapiens)	9068941	protein:decreased expression:striatum (human)	RGD	PMID:15857400 and REF_RGD_ID:2289955
TH	Bonobo	Parkinson's disease		ISO	Th (Mus musculus)	9068941	protein:decreased expression:substantia nigra (mouse)	RGD	PMID:21323909 and REF_RGD_ID:5128616
TH	Bonobo	Parkinsonism	treatment	ISO	TH (Homo sapiens)	9068941		RGD	PMID:23831692 and REF_RGD_ID:401700381
TH	Bonobo	Parkinsonism	susceptibility	ISO	TH (Homo sapiens)	9068941	Segawa syndrome more ...	RGD	PMID:7814018 and REF_RGD_ID:1601634
TH	Bonobo	Parkinsonism		ISO	Th (Rattus norvegicus)	9068941	protein:decreased expression:striatum	RGD	PMID:20561938 and REF_RGD_ID:13524532
TH	Bonobo	polycystic ovary syndrome		ISO	Th (Rattus norvegicus)	9068941	mRNA and protein:increased expression:ovary	RGD	PMID:15795180 and REF_RGD_ID:5508374
TH	Bonobo	portal hypertension		ISO	Th (Rattus norvegicus)	9068941	mRNA:decreased expression:superior mesenteric artery (rat)	RGD	PMID:19968782 and REF_RGD_ID:5129480
TH	Bonobo	Reperfusion Injury		ISO	TH (Homo sapiens)	9068941	protein:increased expression:medulla oblongata (human)	RGD	PMID:21061149 and REF_RGD_ID:5128821
TH	Bonobo	traumatic brain injury		ISO	Th (Rattus norvegicus)	9068941	mRNA:increased expression:locus coeruleus	RGD	PMID:25525686 and REF_RGD_ID:597830164
TH	Bonobo	uremia		ISO	Th (Rattus norvegicus)	9068941	protein:decreased activity:brain (rat)	RGD	PMID:2875142 and REF_RGD_ID:5128603
TH	Bonobo	withdrawal disorder		ISO	Th (Rattus norvegicus)	9068941	protein:increased serine phosphorylation:brainstem (rat)	RGD	PMID:20973778 and REF_RGD_ID:5128830

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TH	Bonobo	Beckwith-Wiedemann syndrome		ISO	TH (Homo sapiens)	8554872	ClinVar Annotator: match by term: Beckwith-Wiedemann syndrome	ClinVar	PMID:21910219 more ...
TH	Bonobo	delta beta-thalassemia		ISO	TH (Homo sapiens)	8554872	ClinVar Annotator: match by term: Thalassemia and gamma-delta-beta	ClinVar	PMID:2798417
TH	Bonobo	developmental and epileptic encephalopathy		ISO	TH (Homo sapiens)	8554872	ClinVar Annotator: match by term: Developmental and epileptic encephalopathy	ClinVar	PMID:28492532
TH	Bonobo	DOPA-responsive dystonia		ISO	TH (Homo sapiens)	8554872	ClinVar Annotator: match by term: Dystonia 5	ClinVar	PMID:18554280 more ...
TH	Bonobo	dystonia		ISO	TH (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:10407773 more ...
TH	Bonobo	dystonia		ISO	TH (Homo sapiens)	8554872	ClinVar Annotator: match by term: Dystonic disorder	ClinVar	PMID:10407773 more ...
TH	Bonobo	early infantile epileptic encephalopathy		ISO	TH (Homo sapiens)	8554872	ClinVar Annotator: match by term: Early infantile epileptic encephalopathy	ClinVar	PMID:28492532
TH	Bonobo	generalized dystonia		ISO	TH (Homo sapiens)	8554872	ClinVar Annotator: match by term: Generalized dystonia	ClinVar	PMID:22572540 more ...
TH	Bonobo	genetic disease		ISO	TH (Homo sapiens)	8554872	ClinVar Annotator: match by term: Inborn genetic diseases	ClinVar	PMID:11246459 more ...
TH	Bonobo	Hyperproinsulinemia		ISO	TH (Homo sapiens)	8554872	ClinVar Annotator: match by term: Hyperproinsulinemia	ClinVar	PMID:25741868 and PMID:33953728
TH	Bonobo	Hypoinsulinemia		ISO	TH (Homo sapiens)	8554872	ClinVar Annotator: match by term: Hypoinsulinemia	ClinVar	PMID:12610512 more ...
TH	Bonobo	immunodeficiency 39		ISO	TH (Homo sapiens)	8554872	ClinVar Annotator: match by term: Immunodeficiency 39	ClinVar	PMID:28492532
TH	Bonobo	maturity-onset diabetes of the young		ISO	TH (Homo sapiens)	8554872	ClinVar Annotator: match by term: Maturity onset diabetes mellitus in young	ClinVar	PMID:11921414 more ...
TH	Bonobo	maturity-onset diabetes of the young type 1		ISO	TH (Homo sapiens)	8554872	ClinVar Annotator: match by term: Type 2 diabetes mellitus	ClinVar	PMID:25741868 more ...
TH	Bonobo	maturity-onset diabetes of the young type 10		ISO	TH (Homo sapiens)	8554872	ClinVar Annotator: match by term: Maturity-onset diabetes of the young type 10	ClinVar	PMID:11921414 more ...
TH	Bonobo	neonatal diabetes mellitus		ISO	TH (Homo sapiens)	8554872	ClinVar Annotator: match by term: Neonatal diabetes mellitus	ClinVar	PMID:25741868 and PMID:27635400
TH	Bonobo	neuronal ceroid lipofuscinosis		ISO	TH (Homo sapiens)	8554872	ClinVar Annotator: match by term: Neuronal ceroid lipofuscinosis	ClinVar	PMID:28492532
TH	Bonobo	Permanent Neonatal Diabetes Mellitus 4		ISO	TH (Homo sapiens)	8554872	ClinVar Annotator: match by term: Diabetes mellitus and permanent neonatal 4	ClinVar	PMID:25741868 more ...
TH	Bonobo	schizophrenia		ISO	TH (Homo sapiens)	8554872	ClinVar Annotator: match by term: Schizophrenia	ClinVar	PMID:20301610 more ...
TH	Bonobo	Segawa Syndrome, Autosomal Recessive		ISO	TH (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:10407773 more ...
TH	Bonobo	Segawa Syndrome, Autosomal Recessive		ISO	TH (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:10407773 more ...
TH	Bonobo	transient neonatal diabetes mellitus		ISO	TH (Homo sapiens)	8554872	ClinVar Annotator: match by term: Transient Neonatal Diabetes and Dominant/Recessive	ClinVar	PMID:11921414 more ...
TH	Bonobo	type 1 diabetes mellitus		ISO	TH (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:11921414 more ...
TH	Bonobo	type 1 diabetes mellitus 2		ISO	TH (Homo sapiens)	8554872	ClinVar Annotator: match by term: Type 1 diabetes mellitus 2	ClinVar	PMID:18162506 more ...
TH	Bonobo	type 2 diabetes mellitus		ISO	TH (Homo sapiens)	8554872	ClinVar Annotator: match by term: Type II diabetes mellitus	ClinVar	PMID:25741868 more ...
TH	Bonobo	Type 2 Diabetes Mellitus 1		ISO	TH (Homo sapiens)	8554872	ClinVar Annotator: match by term: Type 1 diabetes mellitus 2	ClinVar	PMID:18162506 more ...

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TH	Bonobo	brain disease		ISO	TH (Homo sapiens)	9068941	CTD Direct Evidence: therapeutic	CTD	PMID:7842013
TH	Bonobo	Catalepsy		ISO	TH (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:10984662 and PMID:9822156
TH	Bonobo	Drug-Induced Dyskinesia		ISO	TH (Homo sapiens)	9068941	CTD Direct Evidence: therapeutic	CTD	PMID:15659429
TH	Bonobo	essential hypertension		ISO	TH (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:34453990
TH	Bonobo	heart disease		ISO	TH (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:9822156
TH	Bonobo	hepatocellular carcinoma		ISO	TH (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:21472284
TH	Bonobo	Hyperkinesis		ISO	TH (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:9822156
TH	Bonobo	hypertension		ISO	TH (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:27659729 more ...
TH	Bonobo	intellectual disability		ISO	TH (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:21937992
TH	Bonobo	learning disability		ISO	TH (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:10984662 and PMID:9822156
TH	Bonobo	Lewy body dementia		ISO	TH (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:30236862
TH	Bonobo	Nerve Degeneration		ISO	TH (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:12871582
TH	Bonobo	neuroblastoma		ISO	TH (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:25174395
TH	Bonobo	Parkinson's disease		ISO	TH (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:30236862
TH	Bonobo	Parkinsonism		ISO	TH (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:11246459 and PMID:8817341
TH	Bonobo	pheochromocytoma		ISO	TH (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:22569243

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TH	Bonobo	Segawa Syndrome, Autosomal Recessive		ISO	TH (Homo sapiens)	7240710		OMIM

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TH	Bonobo	aminergic neurotransmitter loading into synaptic vesicle		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:19903816 and REF_RGD_ID:5128868
TH	Bonobo	animal organ morphogenesis	acts_upstream_of_or_within	IEA	UniProtKB:P24529 and ensembl:ENSMUSP00000000219	150520179		Ensembl	GO_REF:0000107
TH	Bonobo	aromatic amino acid metabolic process	involved_in	IEA	InterPro:IPR001273 more ...	150520179		InterPro	GO_REF:0000002
TH	Bonobo	catecholamine biosynthetic process		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:20025246 and REF_RGD_ID:4139888
TH	Bonobo	catecholamine biosynthetic process	involved_in	IEA	UniProtKB-KW:KW-0127	150520179		UniProt	GO_REF:0000043
TH	Bonobo	catecholamine biosynthetic process	involved_in	IEA	InterPro:IPR005962	150520179		InterPro	GO_REF:0000002
TH	Bonobo	cellular response to alkaloid		ISO	Th (Rattus norvegicus)	9068941	asimilobine	RGD	PMID:18696327 and REF_RGD_ID:5129084
TH	Bonobo	cellular response to glucose stimulus		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:21217063 and REF_RGD_ID:5128715
TH	Bonobo	cellular response to growth factor stimulus		ISO	Th (Rattus norvegicus)	9068941	nerve growth factor	RGD	PMID:17306206 and REF_RGD_ID:5129106
TH	Bonobo	cellular response to manganese ion		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:19781568 and REF_RGD_ID:5130971
TH	Bonobo	cellular response to nicotine		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:20827341 and REF_RGD_ID:5129209
TH	Bonobo	cellular response to xenobiotic stimulus		ISO	Th (Rattus norvegicus)	9068941	L-DOPA	RGD	PMID:18602388 and REF_RGD_ID:5129085
TH	Bonobo	cerebral cortex development		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:21295554 and REF_RGD_ID:5128671
TH	Bonobo	circadian sleep/wake cycle		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:20980612 and REF_RGD_ID:5128829
TH	Bonobo	cognition		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:20096955 and REF_RGD_ID:5129469
TH	Bonobo	dopamine biosynthetic process	involved_in	IEA	UniProtKB:P07101 and ensembl:ENSP00000325951	150520179		Ensembl	GO_REF:0000107
TH	Bonobo	dopamine biosynthetic process	involved_in	IEA	UniPathway:UPA00747	150520179		UniProt	GO_REF:0000041
TH	Bonobo	dopamine biosynthetic process from tyrosine		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:19584816 more ...
TH	Bonobo	dopamine biosynthetic process from tyrosine	acts_upstream_of_or_within	IEA	UniProtKB:P24529 and ensembl:ENSMUSP00000000219	150520179		Ensembl	GO_REF:0000107
TH	Bonobo	dopamine biosynthetic process from tyrosine	involved_in	IEA	PANTHER:PTN000895530 and PANTHER:PTN002607616	150520179		TreeGrafter	GO_REF:0000118
TH	Bonobo	eating behavior	acts_upstream_of_or_within	IEA	UniProtKB:P24529 and ensembl:ENSMUSP00000000219	150520179		Ensembl	GO_REF:0000107
TH	Bonobo	embryonic camera-type eye morphogenesis	involved_in	IEA	UniProtKB:P24529 and ensembl:ENSMUSP00000000219	150520179		Ensembl	GO_REF:0000107
TH	Bonobo	epinephrine biosynthetic process	involved_in	IEA	UniProtKB:P07101 and ensembl:ENSP00000325951	150520179		Ensembl	GO_REF:0000107
TH	Bonobo	eye photoreceptor cell development	involved_in	IEA	UniProtKB:P24529 and ensembl:ENSMUSP00000000219	150520179		Ensembl	GO_REF:0000107
TH	Bonobo	fatty acid metabolic process		ISO	Th (Rattus norvegicus)	9068941	docosahexaenoic acid	RGD	PMID:21071351 and REF_RGD_ID:5128814
TH	Bonobo	glycoside metabolic process		ISO	Th (Rattus norvegicus)	9068941	catalponol	RGD	PMID:20183248 and REF_RGD_ID:5128866
TH	Bonobo	heart development		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:21280046 and REF_RGD_ID:5128679
TH	Bonobo	heart development	acts_upstream_of_or_within	IEA	UniProtKB:P24529 and ensembl:ENSMUSP00000000219	150520179		Ensembl	GO_REF:0000107
TH	Bonobo	heart development	involved_in	IEA	PANTHER:PTN000895530 and PANTHER:PTN002607616	150520179		TreeGrafter	GO_REF:0000118
TH	Bonobo	hyaloid vascular plexus regression	involved_in	IEA	UniProtKB:P24529 and ensembl:ENSMUSP00000000219	150520179		Ensembl	GO_REF:0000107
TH	Bonobo	isoquinoline alkaloid metabolic process		ISO	Th (Rattus norvegicus)	9068941	anonaine	RGD	PMID:18305432 and REF_RGD_ID:5129087
TH	Bonobo	learning	acts_upstream_of_or_within	IEA	UniProtKB:P24529 and ensembl:ENSMUSP00000000219	150520179		Ensembl	GO_REF:0000107
TH	Bonobo	locomotory behavior	acts_upstream_of_or_within	IEA	UniProtKB:P24529 and ensembl:ENSMUSP00000000219	150520179		Ensembl	GO_REF:0000107
TH	Bonobo	mating behavior	acts_upstream_of_or_within	IEA	UniProtKB:P24529 and ensembl:ENSMUSP00000000219	150520179		Ensembl	GO_REF:0000107
TH	Bonobo	memory	acts_upstream_of_or_within	IEA	UniProtKB:P24529 and ensembl:ENSMUSP00000000219	150520179		Ensembl	GO_REF:0000107
TH	Bonobo	norepinephrine biosynthetic process	involved_in	IEA	UniProtKB:P07101 and ensembl:ENSP00000325951	150520179		Ensembl	GO_REF:0000107
TH	Bonobo	phthalate metabolic process		ISO	Th (Rattus norvegicus)	9068941	mono-2-ethylhexyl phthalate	RGD	PMID:21145954 and REF_RGD_ID:5128805
TH	Bonobo	phytoalexin metabolic process		ISO	Th (Rattus norvegicus)	9068941	scoparone	RGD	PMID:19185027 and REF_RGD_ID:5128879
TH	Bonobo	regulation of heart contraction	acts_upstream_of_or_within	IEA	UniProtKB:P24529 and ensembl:ENSMUSP00000000219	150520179		Ensembl	GO_REF:0000107
TH	Bonobo	response to activity		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:21276429 and REF_RGD_ID:5128681
TH	Bonobo	response to amphetamine		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:21078367 and REF_RGD_ID:5128808
TH	Bonobo	response to corticosterone		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:19494803 and REF_RGD_ID:5130973
TH	Bonobo	response to curcumin		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:20951685 and REF_RGD_ID:5128840
TH	Bonobo	response to electrical stimulus		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:21296669 and REF_RGD_ID:5128670
TH	Bonobo	response to estradiol		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:11914591 and REF_RGD_ID:727567
TH	Bonobo	response to ethanol		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:16713504 and REF_RGD_ID:5130703
TH	Bonobo	response to ethanol	involved_in	IEA	UniProtKB:P07101 and ensembl:ENSP00000325951	150520179		Ensembl	GO_REF:0000107
TH	Bonobo	response to ethanol	involved_in	IEA	PANTHER:PTN000895530 and PANTHER:PTN002607616	150520179		TreeGrafter	GO_REF:0000118
TH	Bonobo	response to ether		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:15896472 and REF_RGD_ID:5130730
TH	Bonobo	response to growth factor		ISO	Th (Rattus norvegicus)	9068941	brain-derived neurotrophic factor	RGD	PMID:21236244 and REF_RGD_ID:5128712
TH	Bonobo	response to herbicide		ISO	Th (Rattus norvegicus)	9068941	paraquat	RGD	PMID:20553223 and REF_RGD_ID:5130934
TH	Bonobo	response to hypoxia		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:12692140 more ...
TH	Bonobo	response to hypoxia	involved_in	IEA	UniProtKB:P07101 and ensembl:ENSP00000325951	150520179		Ensembl	GO_REF:0000107
TH	Bonobo	response to hypoxia	involved_in	IEA	PANTHER:PTN000895530 and PANTHER:PTN002607616	150520179		TreeGrafter	GO_REF:0000118
TH	Bonobo	response to immobilization stress		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:11858766 and REF_RGD_ID:727666
TH	Bonobo	response to insecticide		ISO	Th (Rattus norvegicus)	9068941	rotenone	RGD	PMID:21277943 and REF_RGD_ID:5128680
TH	Bonobo	response to isolation stress		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:19893991 and REF_RGD_ID:9684986
TH	Bonobo	response to light stimulus		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:21185915 and REF_RGD_ID:5128767
TH	Bonobo	response to lipopolysaccharide		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:21239462 and REF_RGD_ID:5128710
TH	Bonobo	response to metal ion		ISO	Th (Rattus norvegicus)	9068941	welding fumes Mn more ...	RGD	PMID:20224926 and REF_RGD_ID:5130952
TH	Bonobo	response to nicotine		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:17437548 and REF_RGD_ID:5129090
TH	Bonobo	response to nutrient levels		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:21364997 and REF_RGD_ID:5128611
TH	Bonobo	response to peptide hormone		ISO	Th (Rattus norvegicus)	9068941	endothelins 1 and 3	RGD	PMID:21129429 and REF_RGD_ID:5128806
TH	Bonobo	response to pyrethroid		ISO	Th (Rattus norvegicus)	9068941	deltamethrin	RGD	PMID:16229977 and REF_RGD_ID:5129144
TH	Bonobo	response to salt stress		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:21113619 and REF_RGD_ID:5128807
TH	Bonobo	response to steroid hormone		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:11883789 and REF_RGD_ID:1601633
TH	Bonobo	response to xenobiotic stimulus		ISO	Th (Rattus norvegicus)	9068941	haloperidol and risperidone	RGD	PMID:21396352 and REF_RGD_ID:5128664
TH	Bonobo	response to zinc ion		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:20553223 and REF_RGD_ID:5130934
TH	Bonobo	social behavior		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:15345906 and REF_RGD_ID:5130765
TH	Bonobo	sphingolipid metabolic process		ISO	Th (Rattus norvegicus)	9068941	sphingosine 1-phosphate	RGD	PMID:21076868 and REF_RGD_ID:5128811
TH	Bonobo	synaptic transmission, dopaminergic	acts_upstream_of_or_within	IEA	UniProtKB:P24529 and ensembl:ENSMUSP00000000219	150520179		Ensembl	GO_REF:0000107
TH	Bonobo	terpene metabolic process		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:20934257 and REF_RGD_ID:5128841
TH	Bonobo	visual perception	involved_in	IEA	UniProtKB:P24529 and ensembl:ENSMUSP00000000219	150520179		Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TH	Bonobo	axon		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:14681933 and REF_RGD_ID:1580024
TH	Bonobo	axon	located_in	IEA	UniProtKB:P24529 and ensembl:ENSMUSP00000000219	150520179		Ensembl	GO_REF:0000107
TH	Bonobo	axon	located_in	IEA	PANTHER:PTN000895530 and PANTHER:PTN002607616	150520179		TreeGrafter	GO_REF:0000118
TH	Bonobo	axon	located_in	IEA	UniProtKB-SubCell:SL-0279	150520179		UniProt	GO_REF:0000044
TH	Bonobo	cell projection	located_in	IEA	UniProtKB-KW:KW-0966	150520179		UniProt	GO_REF:0000043
TH	Bonobo	cytoplasm	located_in	IEA	UniProtKB:P07101 more ...	150520179		Ensembl	GO_REF:0000107
TH	Bonobo	cytoplasm	located_in	IEA	PANTHER:PTN000895530 and PANTHER:PTN002607616	150520179		TreeGrafter	GO_REF:0000118
TH	Bonobo	cytoplasm	located_in	IEA	UniProtKB-KW:KW-0963	150520179		UniProt	GO_REF:0000043
TH	Bonobo	cytoplasmic side of plasma membrane	located_in	IEA	UniProtKB:P07101 and ensembl:ENSP00000325951	150520179		Ensembl	GO_REF:0000107
TH	Bonobo	cytoplasmic vesicle	located_in	IEA	UniProtKB:P07101 and ensembl:ENSP00000325951	150520179		Ensembl	GO_REF:0000107
TH	Bonobo	cytoplasmic vesicle membrane	located_in	ISO	Th (Rattus norvegicus)	9068941	PMID:11943812	BHF-UCL	PMID:11943812 and REF_RGD_ID:5129111
TH	Bonobo	dendrite		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:21362438 and REF_RGD_ID:5128613
TH	Bonobo	melanosome membrane	located_in	IEA	UniProtKB:P07101 and ensembl:ENSP00000325951	150520179		Ensembl	GO_REF:0000107
TH	Bonobo	mitochondrion	located_in	ISO	Th (Rattus norvegicus)	9068941	PMID:11943812	BHF-UCL	PMID:11943812 and REF_RGD_ID:5129111
TH	Bonobo	neuron projection	located_in	IEA	UniProtKB:P07101 more ...	150520179		Ensembl	GO_REF:0000107
TH	Bonobo	neuron projection terminus		ISO	Th (Chinchilla lanigera)	9068941		RGD	PMID:23971205 more ...
TH	Bonobo	neuronal cell body		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:21325515 and REF_RGD_ID:5128615
TH	Bonobo	nucleus	located_in	IEA	UniProtKB:P07101 more ...	150520179		Ensembl	GO_REF:0000107
TH	Bonobo	perikaryon		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:20434498 and REF_RGD_ID:5129701
TH	Bonobo	perikaryon		ISO	Th (Chinchilla lanigera)	9068941		RGD	PMID:23971205 more ...
TH	Bonobo	perikaryon	located_in	IEA	UniProtKB:P24529 and ensembl:ENSMUSP00000000219	150520179		Ensembl	GO_REF:0000107
TH	Bonobo	perikaryon	located_in	IEA	PANTHER:PTN000895530 and PANTHER:PTN002607616	150520179		TreeGrafter	GO_REF:0000118
TH	Bonobo	perinuclear region of cytoplasm	located_in	IEA	UniProtKB-SubCell:SL-0198	150520179		UniProt	GO_REF:0000044
TH	Bonobo	perinuclear region of cytoplasm	located_in	IEA	UniProtKB:P24529 and ensembl:ENSMUSP00000000219	150520179		Ensembl	GO_REF:0000107
TH	Bonobo	smooth endoplasmic reticulum	located_in	IEA	UniProtKB:P07101 and ensembl:ENSP00000325951	150520179		Ensembl	GO_REF:0000107
TH	Bonobo	synapse	located_in	IEA	GO:0001963	150520179		GOC	GO_REF:0000108
TH	Bonobo	synaptic vesicle		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:15496595 more ...
TH	Bonobo	terminal bouton		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:14681933 and REF_RGD_ID:1580024

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TH	Bonobo	amino acid binding		ISO	Th (Rattus norvegicus)	9068941	L-tyrosine	RGD	PMID:19489646 more ...
TH	Bonobo	amino acid binding		ISO	tyrosine	9068941		RGD	PMID:15639226 and REF_RGD_ID:1580027
TH	Bonobo	dopamine binding		ISO	dopamine	9068941		RGD	PMID:15639226 and REF_RGD_ID:1580027
TH	Bonobo	enzyme binding	enables	IEA	UniProtKB:P07101 and ensembl:ENSP00000325951	150520179		Ensembl	GO_REF:0000107
TH	Bonobo	ferric iron binding		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:16475826 more ...
TH	Bonobo	ferrous iron binding		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:16475826 more ...
TH	Bonobo	identical protein binding	enables	ISO	UniProtKB:P07101-3	9068941	PMID:32296183	IntAct	PMID:32296183
TH	Bonobo	iron ion binding	enables	IEA	InterPro:IPR001273 more ...	150520179		InterPro	GO_REF:0000002
TH	Bonobo	metal ion binding	enables	IEA	UniProtKB-KW:KW-0479	150520179		UniProt	GO_REF:0000043
TH	Bonobo	monooxygenase activity	enables	IEA	InterPro:IPR001273 more ...	150520179		InterPro	GO_REF:0000002
TH	Bonobo	monooxygenase activity	enables	IEA	UniProtKB-KW:KW-0503	150520179		UniProt	GO_REF:0000043
TH	Bonobo	oxidoreductase activity	enables	IEA	UniProtKB-KW:KW-0560	150520179		UniProt	GO_REF:0000043
TH	Bonobo	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen	enables	IEA	InterPro:IPR019773 and InterPro:IPR019774	150520179		InterPro	GO_REF:0000002
TH	Bonobo	oxygen binding		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:19489646 more ...
TH	Bonobo	protein binding		ISO	Slc18a2 (Rattus norvegicus)	9068941		RGD	PMID:19903816 and REF_RGD_ID:5128868
TH	Bonobo	protein binding	enables	ISO	UniProtKB:C9J7I0 more ...	9068941	PMID:32296183	IntAct	PMID:32296183
TH	Bonobo	protein binding	enables	ISO	UniProtKB:Q6Q0N3	9068941	PMID:38382359	UniProt	PMID:38382359 and REF_RGD_ID:408345199
TH	Bonobo	protein binding	enables	ISO	UniProtKB:Q6Q0N3	9068941	PMID:31279527	UniProt	PMID:31279527 and REF_RGD_ID:408345212
TH	Bonobo	protein binding		ISO	Snca (Rattus norvegicus)	9068941		RGD	PMID:11943812 and REF_RGD_ID:5129111
TH	Bonobo	protein binding		ISO	Prkcd (Rattus norvegicus)	9068941		RGD	PMID:17507557 and REF_RGD_ID:8694085
TH	Bonobo	protein binding		ISO	Slc18a1 (Rattus norvegicus)	9068941		RGD	PMID:19903816 and REF_RGD_ID:5128868
TH	Bonobo	protein binding	enables	ISO	UniProtKB:P37840	9068941	PMID:11943812	BHF-UCL	PMID:11943812
TH	Bonobo	protein binding	enables	ISO	UniProtKB:Q99497	9068941	PMID:19703902	ParkinsonsUK-UCL	PMID:19703902
TH	Bonobo	protein domain specific binding		ISO	SLC18A2 (Homo sapiens)	9068941	cytoplasmic domains	RGD	PMID:19903816 and REF_RGD_ID:5128868
TH	Bonobo	small molecule binding	enables	ISO	Th (Rattus norvegicus)	9068941	PMID:10375411	DisProt	PMID:10375411 and REF_RGD_ID:152995565
TH	Bonobo	small molecule binding	enables	ISO	Th (Rattus norvegicus)	9068941	PMID:19371093	DisProt	PMID:19371093 and REF_RGD_ID:152995543
TH	Bonobo	tetrahydrobiopterin binding		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:19489646 more ...
TH	Bonobo	tyrosine 3-monooxygenase activity		ISO	Th (Rattus norvegicus)	9068941		RGD	PMID:19489646 more ...
TH	Bonobo	tyrosine 3-monooxygenase activity	enables	IEA	EC:1.14.16.2	150520179		UniProt	GO_REF:0000003
TH	Bonobo	tyrosine 3-monooxygenase activity	enables	IEA	UniProtKB:P07101 and ensembl:ENSP00000325951	150520179		Ensembl	GO_REF:0000107
TH	Bonobo	tyrosine 3-monooxygenase activity	enables	IEA	InterPro:IPR005962 and InterPro:IPR021164	150520179		InterPro	GO_REF:0000002
TH	Bonobo	tyrosine 3-monooxygenase activity	enables	IEA	PANTHER:PTN000895530 and PANTHER:PTN002607616	150520179		TreeGrafter	GO_REF:0000118

RGD Manual Annotations

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TH	Bonobo	dopamine biosynthetic pathway		ISO	TH (Homo sapiens)	9068941		RGD	PMID:19342614 and REF_RGD_ID:4139904
TH	Bonobo	epinephrine biosynthetic pathway		ISO	TH (Homo sapiens)	9068941		RGD	PMID:19342614 and REF_RGD_ID:4139904
TH	Bonobo	norepinephrine biosynthetic pathway		ISO	TH (Homo sapiens)	9068941		RGD	PMID:19342614 and REF_RGD_ID:4139904

Imported Annotations - SMPDB

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TH	Bonobo	aromatic L-amino acid decarboxylase deficiency pathway		ISO	TH (Homo sapiens)	9068941		SMPDB	SMP:00170
TH	Bonobo	catecholamine biosynthetic pathway		ISO	TH (Homo sapiens)	9068941		SMPDB	SMP:00012

PMID:22301074	PMID:30032202

TH
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	4,590,095 - 4,597,992 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	3,801,867 - 3,809,764 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	2,204,820 - 2,212,750 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	2,234,095 - 2,242,030 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	2,231,248 - 2,242,433 (-)	Ensembl	panpan1.1		panPan2

TH
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	2,163,929 - 2,171,815 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	2,163,929 - 2,171,815 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	2,185,159 - 2,193,045 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	2,141,735 - 2,149,611 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	2,141,735 - 2,149,605	NCBI
Celera	11	2,221,752 - 2,229,624 (-)	NCBI		Celera
Cytogenetic Map	11	p15.5	NCBI
HuRef	11	1,975,424 - 1,983,299 (-)	NCBI		HuRef
CHM1_1	11	2,183,941 - 2,191,817 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	2,253,295 - 2,261,192 (-)	NCBI		T2T-CHM13v2.0

Th
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	142,446,516 - 142,453,732 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	142,446,489 - 142,484,865 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	142,892,779 - 142,899,995 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	142,892,752 - 142,931,128 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	150,078,681 - 150,085,871 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	142,702,166 - 142,709,356 (-)	NCBI		MGSCv36	mm8
Celera	7	142,648,392 - 142,655,582 (-)	NCBI		Celera
Cytogenetic Map	7	F5	NCBI
cM Map	7	88.06	NCBI

Th
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	207,500,959 - 207,508,276 (-)	NCBI		GRCr8
mRatBN7.2	1	198,071,500 - 198,078,832 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	198,071,503 - 198,109,767 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	206,450,387 - 206,457,507 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	213,537,252 - 213,544,373 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	206,211,403 - 206,218,524 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	216,073,034 - 216,080,287 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	216,073,031 - 216,080,287 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	222,935,462 - 222,942,715 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	203,164,253 - 203,171,506 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	203,317,712 - 203,324,972 (-)	NCBI
Celera	1	195,642,057 - 195,649,203 (-)	NCBI		Celera
RH 2.0 Map	1	1080.1	RGD
Cytogenetic Map	1	q41	NCBI

Th
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955422	13,943,552 - 13,951,137 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955422	13,943,590 - 13,951,102 (-)	NCBI	ChiLan1.0	ChiLan1.0

TH
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	46,327,136 - 46,334,973 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	46,327,137 - 46,335,602 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	44,936,923 - 44,944,750 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	47,006,609 - 47,014,412 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	47,006,611 - 47,014,441 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	46,455,359 - 46,462,897 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	46,035,687 - 46,043,215 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	46,782,129 - 46,789,967 (-)	NCBI		UU_Cfam_GSD_1.0

Th
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	2,535,447 - 2,543,939 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936794	478,614 - 487,061 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936794	478,651 - 486,887 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TH
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	1,499,620 - 1,506,170 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	1,499,628 - 1,506,180 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

TH
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	1,969,194 - 1,977,263 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	1,966,460 - 1,977,218 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	99,163,059 - 99,174,711 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Th
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624767	15,003,092 - 15,010,154 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624767	15,003,073 - 15,010,207 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	XM_003816061	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008969091	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000050732 ⟹ ENSPPAP00000027889

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	11	2,231,248 - 2,242,433 (-)	Ensembl

Ensembl Acc Id:

ENSPPAT00000050739 ⟹ ENSPPAP00000027896

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	11	2,234,095 - 2,241,958 (-)	Ensembl

Ensembl Acc Id:

ENSPPAT00000050742 ⟹ ENSPPAP00000027899

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	11	2,234,395 - 2,241,939 (-)	Ensembl

RefSeq Acc Id:

XM_003816061 ⟹ XP_003816109

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	9	4,590,095 - 4,597,992 (-)	NCBI
NHGRI_mPanPan1	11	3,801,867 - 3,809,764 (-)	NCBI
Mhudiblu_PPA_v0	11	2,204,820 - 2,212,750 (-)	NCBI
PanPan1.1	11	2,234,095 - 2,242,030 (-)	NCBI

Sequence:

show sequence

GGACCCAGAGGGGGCTTTGACGTCAGCTCAGCTTATAAGAGGCTGCTGGGCCAGGGCTGTGGAGACGGAGCCCGGACCTCCACACTGAGCCATGCCCACCCCCGACGCCACCACGCCACAGGCCAAGG
GCTTCCGCAGGGCCGTGTCTGAGCTGGATGCCAAGCAGGCAGAGGCCATCATGTCCCCGCGGTTCATTGGGCGCAGGCAGAGCCTCATCGAGGACGCCCGCAAGGAGCGGGAGGCGGCGGTGGCAGCA
GCGGCCGCTGCAGTCCCCTCGGAGCCCGGGGACCCCCTGGAGGCCGTGGCCTTTGAGGAGAAGGAGGGGAAGGCCGTGCTAAACCTGCTCTTCTCCCCGAGGGCCACCAAGCCCTCCGCGCTGTCCCG
AGCTGTGAAGGTGTTTGAGACGTTTGAAGCCAAAATCCACCATCTAGAGACCCGGCCCGCCCAGAGGCCGCGAGCTGGGGGCCCCCACCTGGAGTACTTCGTGCGCCTCGAGGTGCGCCGAGGGGACC
TGGCCGCCCTGCTCAGTGGTGTGCGCCAGGTGTCAGAGGACGTGCGCAGCCCCGCGGGGCCCAAGGTCCCCTGGTTCCCAAGAAAAGTGTCAGAGCTGGACAAGTGTCATCACCTGGTCACCAAGTTC
GACCCTGACCTGGACTTGGACCACCCGGGCTTCTCGGACCAGGTGTACCGCCAGCGCAGGAAGCTGATTGCTGAGATCGCCTTCCAGTACAGGCACGGCGACCCGATTCCCCGTGTGGAGTACACCGC
CGAGGAGATTGCCACCTGGAAGGAGGTCTACACCACGCTGAAGGGCCTCTACGCCACGCACGCCTGCGGGGAGCACCTGGAGGCCTTTGCTTTGCTGGAGCGCTTCAGCGGCTACCGGGAAGACAATA
TCCCCCAGCTGGAGGACGTCTCCCGCTTCCTGAAGGAGCGCACGGGCTTCCAGCTGCGGCCTGTGGCCGGCCTGCTGTCCGCCCGGGACTTCCTGGCCAGCCTGGCCTTCCGCGTGTTCCAGTGCACC
CAGTATATCCGCCACGCGTCCTCGCCCATGCACTCCCCTGAGCCGGACTGCTGCCACGAGCTGCTGGGGCACGTGCCCATGCTGGCCGACCGCACCTTCGCGCAGTTCTCGCAGGACATTGGCCTGGC
ATCCCTGGGGGCCTCGGATGAGGAAATTGAGAAGCTGTCCACGCTGTACTGGTTCACGGTGGAGTTCGGGCTGTGTAAGCAGAATGGGGAGGTGAAGGCCTATGGTGCCGGGCTGCTGTCCTCCTACG
GGGAGCTCCTGCACTGCCTGTCTGAGGAGCCCGAGATTCGGGCCTTCGACCCTGAAGCTGCAGCCGTGCAGCCCTACCAAGACCAGACGTACCAGTCAGTCTACTTCGTGTCTGAGAGCTTCAGTGAC
GCCAAGGACAAGCTCAGGAGCTATGCCTCACGCATCCAGCGCCCCTTCTCCGTGAAGTTCGACCCGTACACGCTGGCCATCGACGTGCTGGACAGCCCCCAGGCCGTGCGGCGCTCCCTGGAGGGTGT
CCAGGATGAGCTGGACACCCTTGCCCATGCGCTGAGTGCCATTGGCTAGGTGCACGGCGTCCCTGAAGGCCCTTCCCAACCTCCCCTGGTCCTGCACTGTCCCGGAGCTCAGGCCCTGGTGAGGGGCT
GGGTCCCGGGTGCCCCCACCTCCCTGCTGCCAGGCTCCCGCTGCCCCTGCACCTGCTTCTCAGCGCAACAGCTGTGTGTGCCCGTGGTGAGGTTGTGCTGCCTGTGGTGAGGTCCTGTCCTGGCTCCC
AGGGTCCTGGGGGCTGCTGCACTGCCCTCTCCCCTTCCCTGACACTGTCTGCTGCCCCAGTCACCGTCACAATAAAAGAAAGTGTGGTCTCTA

hide sequence

RefSeq Acc Id:

XM_008969091 ⟹ XP_008967339

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	9	4,590,095 - 4,597,982 (-)	NCBI
NHGRI_mPanPan1	11	3,801,867 - 3,809,754 (-)	NCBI
Mhudiblu_PPA_v0	11	2,204,820 - 2,212,750 (-)	NCBI
PanPan1.1	11	2,234,095 - 2,242,030 (-)	NCBI

Sequence:

show sequence

GGACCCAGAGGGGGCTTTGACGTCAGCTCAGCTTATAAGAGGCTGCTGGGCCAGGGCTGTGGAGACGGAGCCCGGACCTCCACACTGAGCCATGCCCACCCCCGACGCCACCACGCCACAGGCCAAGG
GCTTCCGCAGGGCCGTGTCTGAGCTGGATGCCAAGCAGGCAGAGGCCATCATGGTAAGAGGGCAGTCCCCGCGGTTCATTGGGCGCAGGCAGAGCCTCATCGAGGACGCCCGCAAGGAGCGGGAGGCG
GCGGTGGCAGCAGCGGCCGCTGCAGTCCCCTCGGAGCCCGGGGACCCCCTGGAGGCCGTGGCCTTTGAGGAGAAGGAGGGGAAGGCCGTGCTAAACCTGCTCTTCTCCCCGAGGGCCACCAAGCCCTC
CGCGCTGTCCCGAGCTGTGAAGGTGTTTGAGACGTTTGAAGCCAAAATCCACCATCTAGAGACCCGGCCCGCCCAGAGGCCGCGAGCTGGGGGCCCCCACCTGGAGTACTTCGTGCGCCTCGAGGTGC
GCCGAGGGGACCTGGCCGCCCTGCTCAGTGGTGTGCGCCAGGTGTCAGAGGACGTGCGCAGCCCCGCGGGGCCCAAGGTCCCCTGGTTCCCAAGAAAAGTGTCAGAGCTGGACAAGTGTCATCACCTG
GTCACCAAGTTCGACCCTGACCTGGACTTGGACCACCCGGGCTTCTCGGACCAGGTGTACCGCCAGCGCAGGAAGCTGATTGCTGAGATCGCCTTCCAGTACAGGCACGGCGACCCGATTCCCCGTGT
GGAGTACACCGCCGAGGAGATTGCCACCTGGAAGGAGGTCTACACCACGCTGAAGGGCCTCTACGCCACGCACGCCTGCGGGGAGCACCTGGAGGCCTTTGCTTTGCTGGAGCGCTTCAGCGGCTACC
GGGAAGACAATATCCCCCAGCTGGAGGACGTCTCCCGCTTCCTGAAGGAGCGCACGGGCTTCCAGCTGCGGCCTGTGGCCGGCCTGCTGTCCGCCCGGGACTTCCTGGCCAGCCTGGCCTTCCGCGTG
TTCCAGTGCACCCAGTATATCCGCCACGCGTCCTCGCCCATGCACTCCCCTGAGCCGGACTGCTGCCACGAGCTGCTGGGGCACGTGCCCATGCTGGCCGACCGCACCTTCGCGCAGTTCTCGCAGGA
CATTGGCCTGGCATCCCTGGGGGCCTCGGATGAGGAAATTGAGAAGCTGTCCACGCTGTACTGGTTCACGGTGGAGTTCGGGCTGTGTAAGCAGAATGGGGAGGTGAAGGCCTATGGTGCCGGGCTGC
TGTCCTCCTACGGGGAGCTCCTGCACTGCCTGTCTGAGGAGCCCGAGATTCGGGCCTTCGACCCTGAAGCTGCAGCCGTGCAGCCCTACCAAGACCAGACGTACCAGTCAGTCTACTTCGTGTCTGAG
AGCTTCAGTGACGCCAAGGACAAGCTCAGGAGCTATGCCTCACGCATCCAGCGCCCCTTCTCCGTGAAGTTCGACCCGTACACGCTGGCCATCGACGTGCTGGACAGCCCCCAGGCCGTGCGGCGCTC
CCTGGAGGGTGTCCAGGATGAGCTGGACACCCTTGCCCATGCGCTGAGTGCCATTGGCTAGGTGCACGGCGTCCCTGAAGGCCCTTCCCAACCTCCCCTGGTCCTGCACTGTCCCGGAGCTCAGGCCC
TGGTGAGGGGCTGGGTCCCGGGTGCCCCCACCTCCCTGCTGCCAGGCTCCCGCTGCCCCTGCACCTGCTTCTCAGCGCAACAGCTGTGTGTGCCCGTGGTGAGGTTGTGCTGCCTGTGGTGAGGTCCT
GTCCTGGCTCCCAGGGTCCTGGGGGCTGCTGCACTGCCCTCTCCCCTTCCCTGACACTGTCTGCTGCCCCAGTCACCGTCACAATAAAAGAAAGTGTGGTCTCTA

hide sequence


Protein RefSeqs	XP_003816109	(Get FASTA)	NCBI Sequence Viewer
	XP_008967339	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000027889.1
	ENSPPAP00000027896.1
	ENSPPAP00000027899.1

RefSeq Acc Id:	XP_003816109 ⟸ XM_003816061
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R9BE28 (UniProtKB/TrEMBL), A0A2R9BMK2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPTPDATTPQAKGFRRAVSELDAKQAEAIMSPRFIGRRQSLIEDARKEREAAVAAAAAAVPSEPGDPLEAVAFEEKEGKAVLNLLFSPRATKPSALSRAVKVFETFEAKIHHLETRPAQRPRAGGPHL EYFVRLEVRRGDLAALLSGVRQVSEDVRSPAGPKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQVYRQRRKLIAEIAFQYRHGDPIPRVEYTAEEIATWKEVYTTLKGLYATHACGEHLEAFA LLERFSGYREDNIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWFTVEFGLCKQNGE VKAYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFVSESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALSAIG hide sequence

RefSeq Acc Id:	XP_008967339 ⟸ XM_008969091
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9BMK2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPTPDATTPQAKGFRRAVSELDAKQAEAIMVRGQSPRFIGRRQSLIEDARKEREAAVAAAAAAVPSEPGDPLEAVAFEEKEGKAVLNLLFSPRATKPSALSRAVKVFETFEAKIHHLETRPAQRPRAG GPHLEYFVRLEVRRGDLAALLSGVRQVSEDVRSPAGPKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQVYRQRRKLIAEIAFQYRHGDPIPRVEYTAEEIATWKEVYTTLKGLYATHACGEHL EAFALLERFSGYREDNIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWFTVEFGLCK QNGEVKAYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFVSESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALSAIG hide sequence

Ensembl Acc Id:

ENSPPAP00000027889 ⟸ ENSPPAT00000050732

Ensembl Acc Id:

ENSPPAP00000027899 ⟸ ENSPPAT00000050742

Ensembl Acc Id:

ENSPPAP00000027896 ⟸ ENSPPAT00000050739

Protein Domains

Biopterin-dependent aromatic amino acid hydroxylase

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000037007	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000050732.1	UniProtKB/TrEMBL
	ENSPPAT00000050739.1	UniProtKB/TrEMBL
	ENSPPAT00000050742.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.800.10	UniProtKB/TrEMBL
	3.30.70.260	UniProtKB/TrEMBL
InterPro	ACT-like_dom_sf	UniProtKB/TrEMBL
	ArAA_hydroxylase	UniProtKB/TrEMBL
	ArAA_hydroxylase_Fe/CU_BS	UniProtKB/TrEMBL
	ArAA_hydroxylase_sf	UniProtKB/TrEMBL
	Aro-AA_hydroxylase_C_sf	UniProtKB/TrEMBL
	Aromatic-AA_hydroxylase_C	UniProtKB/TrEMBL
	Eu_TyrOH_cat	UniProtKB/TrEMBL
	TH_ACT	UniProtKB/TrEMBL
	Tyr_3_mOase	UniProtKB/TrEMBL
	Tyrosine_3-monooxygenase-like	UniProtKB/TrEMBL
	Tyrosine_hydroxylase_CS	UniProtKB/TrEMBL
KEGG Report	pps:100967895	UniProtKB/TrEMBL
NCBI Gene	TH	ENTREZGENE
PANTHER	PTHR11473	UniProtKB/TrEMBL
	TYROSINE 3-MONOOXYGENASE	UniProtKB/TrEMBL
Pfam	Biopterin_H	UniProtKB/TrEMBL
	TH_ACT	UniProtKB/TrEMBL
	TOH_N	UniProtKB/TrEMBL
PIRSF	PIRSF000336	UniProtKB/TrEMBL
PRINTS	FYWHYDRXLASE	UniProtKB/TrEMBL
PROSITE	BH4_AAA_HYDROXYL_1	UniProtKB/TrEMBL
	BH4_AAA_HYDROXYL_2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF55021	UniProtKB/TrEMBL
	SSF56534	UniProtKB/TrEMBL
UniProt	A0A2R9BE28	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9BE39_PANPA	UniProtKB/TrEMBL
	A0A2R9BMK2	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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