Th (tyrosine hydroxylase) - Rat Genome Database
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Gene: Th (tyrosine hydroxylase) Chinchilla lanigera
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Symbol: Th
Name: tyrosine hydroxylase
RGD ID: 8835217
Description: ENCODES a protein that exhibits amino acid binding (ortholog); dopamine binding (ortholog); enzyme binding (ortholog); INVOLVED IN aminergic neurotransmitter loading into synaptic vesicle (ortholog); animal organ morphogenesis (ortholog); catecholamine biosynthetic process (ortholog); PARTICIPATES IN aromatic L-amino acid decarboxylase deficiency pathway; catecholamine biosynthetic pathway; dopamine biosynthetic pathway; ASSOCIATED WITH brain disease (ortholog); Brain Injuries (ortholog); brain ischemia (ortholog); FOUND IN neuron projection terminus; perikaryon; axon (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: tyrosine 3-monooxygenase
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542213,943,552 - 13,951,137 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542213,943,590 - 13,951,102 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aminergic neurotransmitter loading into synaptic vesicle  (ISO)
animal organ morphogenesis  (ISO)
catecholamine biosynthetic process  (ISO)
cellular response to alkaloid  (ISO)
cellular response to drug  (ISO)
cellular response to glucose stimulus  (ISO)
cellular response to growth factor stimulus  (ISO)
cellular response to manganese ion  (ISO)
cellular response to nicotine  (ISO)
cerebral cortex development  (ISO)
circadian sleep/wake cycle  (ISO)
cognition  (ISO)
dopamine biosynthetic process  (ISO)
dopamine biosynthetic process from tyrosine  (ISO)
eating behavior  (ISO)
embryonic camera-type eye morphogenesis  (ISO)
epinephrine biosynthetic process  (ISO)
eye photoreceptor cell development  (ISO)
fatty acid metabolic process  (ISO)
glycoside metabolic process  (ISO)
heart development  (ISO)
hyaloid vascular plexus regression  (ISO)
isoquinoline alkaloid metabolic process  (ISO)
learning  (ISO)
locomotory behavior  (ISO)
mating behavior  (ISO)
memory  (ISO)
multicellular organism aging  (ISO)
norepinephrine biosynthetic process  (ISO)
phthalate metabolic process  (ISO)
phytoalexin metabolic process  (ISO)
regulation of heart contraction  (ISO)
response to activity  (ISO)
response to amphetamine  (ISO)
response to corticosterone  (ISO)
response to drug  (ISO)
response to electrical stimulus  (ISO)
response to estradiol  (ISO)
response to ethanol  (ISO)
response to ether  (ISO)
response to growth factor  (ISO)
response to herbicide  (ISO)
response to hypoxia  (ISO)
response to immobilization stress  (ISO)
response to insecticide  (ISO)
response to isolation stress  (ISO)
response to light stimulus  (ISO)
response to lipopolysaccharide  (ISO)
response to metal ion  (ISO)
response to nicotine  (ISO)
response to nutrient levels  (ISO)
response to organic cyclic compound  (ISO)
response to peptide hormone  (ISO)
response to pyrethroid  (ISO)
response to salt stress  (ISO)
response to steroid hormone  (ISO)
response to water deprivation  (ISO)
response to zinc ion  (ISO)
sensory perception of sound  (ISO)
social behavior  (ISO)
sphingolipid metabolic process  (ISO)
synaptic transmission, dopaminergic  (ISO)
terpene metabolic process  (ISO)
visual perception  (ISO)

References


Genomics

Comparative Map Data
Th
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542213,943,552 - 13,951,137 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542213,943,590 - 13,951,102 (-)NCBIChiLan1.0ChiLan1.0
TH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl112,163,929 - 2,171,877 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl112,163,929 - 2,171,815 (-)EnsemblGRCh38hg38GRCh38
GRCh38112,163,929 - 2,174,081 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37112,185,159 - 2,193,107 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36112,141,735 - 2,149,611 (-)NCBINCBI36hg18NCBI36
Build 34112,141,735 - 2,149,605NCBI
Celera112,221,752 - 2,229,624 (-)NCBI
Cytogenetic Map11p15.5NCBI
HuRef111,975,424 - 1,983,299 (-)NCBIHuRef
CHM1_1112,183,941 - 2,191,817 (-)NCBICHM1_1
Th
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397142,446,516 - 142,453,732 (-)NCBIGRCm39mm39
GRCm387142,892,779 - 142,899,995 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7142,892,752 - 142,931,128 (-)EnsemblGRCm38mm10GRCm38
MGSCv377150,078,681 - 150,085,871 (-)NCBIGRCm37mm9NCBIm37
MGSCv367142,702,166 - 142,709,356 (-)NCBImm8
Celera7142,648,392 - 142,655,582 (-)NCBICelera
Cytogenetic Map7F5NCBI
cM Map788.06NCBI
Th
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01216,073,034 - 216,080,287 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1216,073,031 - 216,080,287 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01222,935,462 - 222,942,715 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41203,164,253 - 203,171,506 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11203,317,712 - 203,324,972 (-)NCBI
Celera1195,642,057 - 195,649,203 (-)NCBICelera
Cytogenetic Map1q41NCBI
RH 2.0 Map11080.1RGD
TH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1112,234,095 - 2,242,030 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl112,231,248 - 2,242,433 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0112,204,820 - 2,212,750 (-)NCBIMhudiblu_PPA_v0panPan3
TH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1846,327,137 - 46,335,602 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11846,327,136 - 46,334,973 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Th
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936794478,651 - 486,887 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl21,499,618 - 1,506,615 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.121,499,628 - 1,506,180 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TH
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl11,966,460 - 1,977,218 (-)Ensembl
ChlSab1.111,969,194 - 1,977,263 (-)NCBI
Th
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476715,003,073 - 15,010,207 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000022931   ⟹   ENSCLAP00000022722
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542213,943,552 - 13,951,137 (-)Ensembl
RefSeq Acc Id: XM_005384197   ⟹   XP_005384254
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542213,943,590 - 13,951,102 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005384254 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005384254   ⟸   XM_005384197
- Sequence:
RefSeq Acc Id: ENSCLAP00000022722   ⟸   ENSCLAT00000022931


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000015576 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000022722 ENTREZGENE
Ensembl Transcript ENSCLAT00000022931 ENTREZGENE
NCBI Gene Th ENTREZGENE