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ONTOLOGY REPORT - ANNOTATIONS


Term:histone H3K9 trimethyltransferase activity
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Accession:GO:0140949 term browser browse the term
Definition:Catalysis of the reaction: L-lysyl9-[histone H3] + 3 S-adenosyl-L-methionine = 3 H+ + N6,N6,N6-trimethyl-L-lysyl9-[histone H3] + 3 S-adenosyl-L-homocysteine. This reaction is the successive addition of three methyl groups to the unmethylated lysine residue at position 9 of histone H3, producing histone H3K9me3.
Synonyms:exact_synonym: histone H3K9 mono/di/trimethylase activity;   histone H3K9 trimethylase activity;   histone lysine N-trimethyltransferase activity (H3-K9 specific)
 broad_synonym: histone H3-K9 trimethylation;   histone H3K9 trimethylation
 xref: EC:2.1.1.355;   RHEA:60276


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histone H3K9 trimethyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G R Prdm2 PR/SET domain 2 enables IEA GO_REF:0000116
GO_REF:0000003
RHEA
UniProt
GO_REF:0000003 GO_REF:0000116 NCBI chr 5:155,421,066...155,531,884
Ensembl chr 5:155,422,134...155,531,825
JBrowse link
G H PRDM2 PR/SET domain 2 enables IEA RHEA
UniProt
GO_REF:0000003 GO_REF:0000116 NCBI chr 1:13,700,188...13,825,079
Ensembl chr 1:13,700,188...13,825,079
JBrowse link
G R Prdm9 PR/SET domain 9 enables IEA GO_REF:0000003
GO_REF:0000116
UniProt
RHEA
GO_REF:0000003 GO_REF:0000116 NCBI chr 1:56,505,579...56,525,726
Ensembl chr 1:56,505,579...56,525,652
JBrowse link
G M Prdm9 PR domain containing 9 enables IEA UniProt GO_REF:0000003 MGI:2152096 NCBI chr17:15,763,334...15,784,636
Ensembl chr17:15,763,341...15,784,616
JBrowse link
G H PRDM9 PR/SET domain 9 enables IEA RHEA
UniProt
GO_REF:0000003 GO_REF:0000116 NCBI chr 5:23,507,155...23,528,093
Ensembl chr 5:23,443,586...23,528,093
JBrowse link
G N Setdb1 SET domain bifurcated histone lysine methyltransferase 1 enables ISO (PMID:14536086) UniProt PMID:14536086 NCBI chrNW_004624772:18,855,405...18,894,285
Ensembl chrNW_004624772:18,855,332...18,894,226
JBrowse link
G G SETDB1 SET domain bifurcated histone lysine methyltransferase 1 enables ISO (PMID:14536086) UniProt PMID:14536086
G P SETDB1 SET domain bifurcated histone lysine methyltransferase 1 enables ISO (PMID:14536086) UniProt PMID:14536086 NCBI chr 4:98,259,801...98,293,238
Ensembl chr 4:98,260,375...98,293,097
JBrowse link
G S Setdb1 SET domain bifurcated histone lysine methyltransferase 1 enables ISO (PMID:14536086) UniProt PMID:14536086 NCBI chrNW_004936580:1,146,286...1,192,842
Ensembl chrNW_004936580:1,146,277...1,192,842
JBrowse link
G D SETDB1 SET domain bifurcated histone lysine methyltransferase 1 enables ISO (PMID:14536086) UniProt PMID:14536086 NCBI chr17:60,035,819...60,069,721
Ensembl chr17:60,037,379...60,069,551
JBrowse link
G B SETDB1 SET domain bifurcated histone lysine methyltransferase 1 enables ISO (PMID:14536086) UniProt PMID:14536086 NCBI chr 1:126,275,719...126,314,043
Ensembl chr 1:129,925,009...129,962,442
JBrowse link
G C Setdb1 SET domain bifurcated histone lysine methyltransferase 1 enables ISO (PMID:14536086) UniProt PMID:14536086 NCBI chrNW_004955588:290,497...338,438
Ensembl chrNW_004955588:290,168...338,426
JBrowse link
G R Setdb1 SET domain bifurcated histone lysine methyltransferase 1 enables ISO (PMID:14536086) RGD PMID:14536086 NCBI chr 2:182,898,738...182,930,283
Ensembl chr 2:182,898,738...182,930,506
JBrowse link
G M Setdb1 SET domain, bifurcated 1 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 3:95,230,836...95,264,513
Ensembl chr 3:95,230,836...95,264,513
JBrowse link
G H SETDB1 SET domain bifurcated histone lysine methyltransferase 1 enables IDA (PMID:14536086) UniProt PMID:14536086 NCBI chr 1:150,926,263...150,964,737
Ensembl chr 1:150,926,263...150,964,744
JBrowse link
G N Suv39h1 SUV39H1 histone lysine methyltransferase enables IEA RHEA
UniProt
GO_REF:0000003 GO_REF:0000116 NCBI chrNW_004624893:499,222...512,341
Ensembl chrNW_004624893:498,973...512,443
JBrowse link
G G SUV39H1 SUV39H1 histone lysine methyltransferase enables IEA UniProt
RHEA
GO_REF:0000003 GO_REF:0000116 NCBI chr  X:45,820,114...45,834,727
Ensembl chr  X:45,822,453...45,834,917
JBrowse link
G P SUV39H1 SUV39H1 histone lysine methyltransferase enables IEA RHEA
Ensembl
UniProt
GO_REF:0000003 GO_REF:0000107 GO_REF:0000116 NCBI chr  X:42,797,309...42,811,457
Ensembl chr  X:42,797,828...42,811,461
JBrowse link
G S Suv39h1 SUV39H1 histone lysine methyltransferase enables IEA RHEA
Ensembl
UniProt
GO_REF:0000003 GO_REF:0000107 GO_REF:0000116 NCBI chrNW_004936721:646,778...661,144
Ensembl chrNW_004936721:646,772...661,091
JBrowse link
G D SUV39H1 SUV39H1 histone lysine methyltransferase enables ISO (PMID:30111536) UniProt PMID:30111536 NCBI chr  X:41,894,623...41,907,854
Ensembl chr  X:41,893,045...41,906,403
JBrowse link
G B SUV39H1 SUV39H1 histone lysine methyltransferase enables IEA RHEA
Ensembl
UniProt
GO_REF:0000003 GO_REF:0000107 GO_REF:0000116 NCBI chr  X:40,993,911...41,007,362
Ensembl chr  X:48,855,494...48,868,131
JBrowse link
G C Suv39h1 SUV39H1 histone lysine methyltransferase enables ISO (PMID:30111536) UniProt PMID:30111536 NCBI chrNW_004955543:258,479...271,128
Ensembl chrNW_004955543:258,479...272,473
JBrowse link
G R Suv39h1 SUV39H1 histone lysine methyltransferase enables ISO (PMID:30111536) RGD PMID:30111536 NCBI chr  X:14,421,028...14,433,993
Ensembl chr  X:14,421,109...14,433,982
JBrowse link
G M Suv39h1 suppressor of variegation 3-9 1 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr  X:7,927,401...7,940,994
Ensembl chr  X:7,927,410...7,940,999
JBrowse link
G H SUV39H1 SUV39H1 histone lysine methyltransferase enables IEA
IDA
(PMID:30111536) RHEA
UniProt
PMID:30111536 GO_REF:0000003 GO_REF:0000116 NCBI chr  X:48,695,554...48,709,016
Ensembl chr  X:48,695,554...48,709,016
JBrowse link
G R Suv39h1-ps1 SUV39H1 histone lysine methyltransferase, pseudogene 1 enables ISO (PMID:30111536) RGD PMID:30111536 NCBI chr  X:141,792,589...141,795,257 JBrowse link
G N Suv39h2 SUV39H2 histone lysine methyltransferase enables IEA UniProt
RHEA
GO_REF:0000003 GO_REF:0000116 NCBI chrNW_004624805:594,986...619,115
Ensembl chrNW_004624805:597,406...618,969
JBrowse link
G G SUV39H2 SUV39H2 histone lysine methyltransferase enables IEA RHEA
UniProt
GO_REF:0000003 GO_REF:0000116 NCBI chr 9:14,900,503...14,924,017
Ensembl chr 9:14,900,945...14,923,447
JBrowse link
G P SUV39H2 SUV39H2 histone lysine methyltransferase enables IEA RHEA
UniProt
GO_REF:0000003 GO_REF:0000116 NCBI chr10:46,874,606...46,900,058
Ensembl chr10:46,873,126...46,900,040
JBrowse link
G S Suv39h2 SUV39H2 histone lysine methyltransferase enables IEA RHEA
UniProt
GO_REF:0000003 GO_REF:0000116 NCBI chrNW_004936613:1,443,663...1,467,776
Ensembl chrNW_004936613:1,443,629...1,467,229
JBrowse link
G B SUV39H2 SUV39H2 histone lysine methyltransferase enables IEA UniProt
RHEA
GO_REF:0000003 GO_REF:0000116 NCBI chr10:14,882,491...14,907,724
Ensembl chr10:15,211,360...15,237,097
JBrowse link
G R Suv39h2 SUV39H2 histone lysine methyltransferase enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr17:74,756,290...74,775,332
Ensembl chr17:74,756,306...74,775,332
JBrowse link
G M Suv39h2 suppressor of variegation 3-9 2 enables IEA UniProt GO_REF:0000003 MGI:2152096 NCBI chr 2:3,456,852...3,476,085
Ensembl chr 2:3,456,852...3,476,068
JBrowse link
G H SUV39H2 SUV39H2 histone lysine methyltransferase enables IEA UniProt
RHEA
GO_REF:0000003 GO_REF:0000116 NCBI chr10:14,878,866...14,904,315
Ensembl chr10:14,878,820...14,904,315
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 189416
    catalytic activity 54171
      catalytic activity, acting on a protein 22375
        protein methyltransferase activity 1020
          protein-lysine N-methyltransferase activity 627
            histone H3K9 methyltransferase activity 124
              histone H3K9 trimethyltransferase activity 34
Path 2
Term Annotations click to browse term
  molecular_function 189416
    catalytic activity 54171
      transferase activity 22311
        transferase activity, transferring one-carbon groups 2186
          methyltransferase activity 2074
            S-adenosylmethionine-dependent methyltransferase activity 1652
              lysine N-methyltransferase activity 628
                protein-lysine N-methyltransferase activity 627
                  histone H3K9 methyltransferase activity 124
                    histone H3K9 trimethyltransferase activity 34
paths to the root