Suv39h2 (SUV39H2 histone lysine methyltransferase) - Rat Genome Database

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Gene: Suv39h2 (SUV39H2 histone lysine methyltransferase) Heterocephalus glaber
Analyze
Symbol: Suv39h2
Name: SUV39H2 histone lysine methyltransferase (Ensembl:suppressor of variegation 3-9 homolog 2)
RGD ID: 18902913
Description: ENCODES a protein that exhibits chromatin binding (ortholog); histone H3 methyltransferase activity (ortholog); histone H3K9me2 methyltransferase activity (ortholog); INVOLVED IN cellular response to hypoxia (ortholog); chromatin remodeling (ortholog); circadian rhythm (ortholog); PARTICIPATES IN histone modification pathway; methionine cycle/metabolic pathway; ASSOCIATED WITH genetic disease (ortholog); histiocytic sarcoma (ortholog); hypoparathyroidism-deafness-renal disease syndrome (ortholog); FOUND IN heterochromatin (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: histone-lysine N-methyltransferase SUV39H2; suppressor of variegation 3-9 homolog 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624805597,406 - 618,969 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624805594,986 - 619,115 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Suv39h2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624805597,406 - 618,969 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624805594,986 - 619,115 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SUV39H2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381014,878,866 - 14,904,315 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1014,878,820 - 14,904,315 (+)EnsemblGRCh38hg38GRCh38
GRCh371014,920,865 - 14,946,314 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361014,960,905 - 14,986,320 (+)NCBINCBI36Build 36hg18NCBI36
Build 341014,960,904 - 14,986,308NCBI
Celera1014,848,822 - 14,874,354 (+)NCBICelera
Cytogenetic Map10p13NCBI
HuRef1014,831,341 - 14,856,796 (+)NCBIHuRef
CHM1_11014,921,216 - 14,946,434 (+)NCBICHM1_1
T2T-CHM13v2.01014,892,831 - 14,918,279 (+)NCBIT2T-CHM13v2.0
Suv39h2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3923,456,852 - 3,476,085 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl23,456,852 - 3,476,068 (-)EnsemblGRCm39 Ensembl
GRCm3823,455,815 - 3,474,986 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl23,455,815 - 3,475,031 (-)EnsemblGRCm38mm10GRCm38
MGSCv3723,373,087 - 3,392,258 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3623,373,092 - 3,392,235 (-)NCBIMGSCv36mm8
Celera23,406,803 - 3,425,973 (-)NCBICelera
Cytogenetic Map2A1NCBI
cM Map21.95NCBI
Suv39h2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81779,665,467 - 79,684,492 (+)NCBIGRCr8
mRatBN7.21774,756,290 - 74,775,332 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1774,756,306 - 74,775,332 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1778,209,501 - 78,228,542 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01782,057,802 - 82,076,828 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01776,092,937 - 76,111,981 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01778,762,897 - 78,782,016 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1778,762,991 - 78,782,016 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01780,406,940 - 80,425,965 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41785,875,954 - 85,894,979 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11785,886,805 - 85,903,145 (+)NCBI
Celera1774,141,962 - 74,160,987 (+)NCBICelera
Cytogenetic Map17q12.3NCBI
Suv39h2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542919,503,197 - 19,528,027 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542919,503,197 - 19,526,454 (-)NCBIChiLan1.0ChiLan1.0
SUV39H2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2827,404,606 - 27,429,895 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11027,409,940 - 27,435,229 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01014,882,491 - 14,907,724 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11015,211,360 - 15,236,272 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1015,211,360 - 15,237,097 (+)Ensemblpanpan1.1panPan2
SUV39H2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1221,715,677 - 21,749,732 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl221,728,964 - 21,749,597 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha218,828,959 - 18,863,033 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0222,017,081 - 22,051,385 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl222,029,347 - 22,051,353 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1219,228,679 - 19,251,776 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0220,052,418 - 20,086,507 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0220,679,024 - 20,713,098 (-)NCBIUU_Cfam_GSD_1.0
Suv39h2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093446,893,110 - 6,922,105 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366131,443,629 - 1,467,229 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366131,443,663 - 1,467,776 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SUV39H2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1046,873,126 - 46,900,040 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11046,874,606 - 46,900,058 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21051,595,641 - 51,633,086 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SUV39H2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1914,900,503 - 14,924,017 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl914,900,945 - 14,923,447 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605120,439,417 - 20,464,204 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000024788   ⟹   ENSHGLP00000024566
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624805597,406 - 618,969 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000024789   ⟹   ENSHGLP00000024567
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624805597,406 - 618,969 (-)Ensembl
RefSeq Acc Id: XM_004921160   ⟹   XP_004921217
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624805594,986 - 619,115 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004921217 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000024566
  ENSHGLP00100015583
GenBank Protein JAO02036 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004921217   ⟸   XM_004921160
- UniProtKB: A0A0P6JCD0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000024566   ⟸   ENSHGLT00000024788
RefSeq Acc Id: ENSHGLP00000024567   ⟸   ENSHGLT00000024789


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000017513 Ensembl, UniProtKB/TrEMBL
  ENSHGLG00100011503 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000024788 UniProtKB/TrEMBL
  ENSHGLT00100015754 UniProtKB/TrEMBL
Gene3D-CATH 2.170.270.10 UniProtKB/TrEMBL
  2.40.50.40 UniProtKB/TrEMBL
InterPro Chromo-like_dom_sf UniProtKB/TrEMBL
  Chromo/chromo_shadow_dom UniProtKB/TrEMBL
  Chromo_domain UniProtKB/TrEMBL
  Chromodomain_CS UniProtKB/TrEMBL
  Histone_H3-K9_MeTrfase UniProtKB/TrEMBL
  Post-SET_dom UniProtKB/TrEMBL
  Pre-SET_dom UniProtKB/TrEMBL
  SET_dom UniProtKB/TrEMBL
  SET_dom_sf UniProtKB/TrEMBL
NCBI Gene Suv39h2 ENTREZGENE
PANTHER HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H UniProtKB/TrEMBL
  HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H2 UniProtKB/TrEMBL
Pfam Chromo UniProtKB/TrEMBL
  Pre-SET UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
PIRSF SUV39_SET UniProtKB/TrEMBL
PROSITE CHROMO_1 UniProtKB/TrEMBL
  CHROMO_2 UniProtKB/TrEMBL
  POST_SET UniProtKB/TrEMBL
  PRE_SET UniProtKB/TrEMBL
  SAM_MT43_SUVAR39_3 UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
SMART CHROMO UniProtKB/TrEMBL
  PostSET UniProtKB/TrEMBL
  PreSET UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
Superfamily-SCOP SSF54160 UniProtKB/TrEMBL
  SSF82199 UniProtKB/TrEMBL
UniProt A0A0P6JCD0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-08-17 Suv39h2  SUV39H2 histone lysine methyltransferase  Suv39h2  suppressor of variegation 3-9 homolog 2  Symbol and/or name change 5135510 APPROVED