Suv39h1 (SUV39H1 histone lysine methyltransferase) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Suv39h1 (SUV39H1 histone lysine methyltransferase) Heterocephalus glaber
Analyze
Symbol: Suv39h1
Name: SUV39H1 histone lysine methyltransferase (Ensembl:suppressor of variegation 3-9 homolog 1)
RGD ID: 18928293
Description: ENCODES a protein that exhibits histone H3K9me2 methyltransferase activity (ortholog); histone methyltransferase activity (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN blastocyst hatching (ortholog); cellular response to glucose starvation (ortholog); cellular response to hypoxia (ortholog); PARTICIPATES IN histone modification pathway; methionine cycle/metabolic pathway; ASSOCIATED WITH autistic disorder (ortholog); Chromosome Breakage (ortholog); congenital disorder of glycosylation type IIm (ortholog); FOUND IN chromatin silencing complex (ortholog); eNoSc complex (ortholog); heterochromatin (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: histone-lysine N-methyltransferase SUV39H1; suppressor of variegation 3-9 homolog 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624893498,973 - 512,443 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624893499,222 - 512,341 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Suv39h1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624893498,973 - 512,443 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624893499,222 - 512,341 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SUV39H1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X48,695,554 - 48,709,016 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX48,695,554 - 48,709,016 (+)EnsemblGRCh38hg38GRCh38
GRCh37X48,553,945 - 48,567,407 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X48,440,075 - 48,452,351 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X48,311,380 - 48,323,651NCBI
CeleraX53,096,600 - 53,108,876 (-)NCBICelera
Cytogenetic MapXp11.23NCBI
HuRefX46,217,119 - 46,229,438 (+)NCBIHuRef
CHM1_1X48,586,299 - 48,598,575 (+)NCBICHM1_1
T2T-CHM13v2.0X48,106,035 - 48,119,497 (+)NCBIT2T-CHM13v2.0
Suv39h1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X7,927,401 - 7,940,994 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX7,927,410 - 7,940,999 (-)EnsemblGRCm39 Ensembl
GRCm38X8,061,171 - 8,074,760 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX8,061,171 - 8,074,760 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X7,638,297 - 7,651,886 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X7,218,263 - 7,231,545 (-)NCBIMGSCv36mm8
CeleraX3,394,838 - 3,408,427 (+)NCBICelera
Cytogenetic MapXA1.1NCBI
cM MapX3.64NCBI
Suv39h1-ps1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X146,828,818 - 146,831,485 (-)NCBIGRCr8
mRatBN7.2X141,792,589 - 141,795,257 (-)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_UtxX143,977,956 - 143,980,623 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X147,518,936 - 147,521,604 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X145,074,611 - 145,077,279 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X146,532,002 - 146,533,538 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X146,551,234 - 146,555,970 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X149,153,769 - 149,155,266 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX137,768,982 - 137,770,518 (-)NCBICelera
Cytogenetic MapXq36NCBI
Suv39h1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955543258,479 - 272,473 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955543258,479 - 271,128 (+)NCBIChiLan1.0ChiLan1.0
SUV39H1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X50,184,506 - 50,197,961 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X50,187,878 - 50,201,333 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X40,993,911 - 41,007,362 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X48,855,494 - 48,868,137 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX48,855,494 - 48,868,131 (+)Ensemblpanpan1.1panPan2
SUV39H1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X41,894,623 - 41,907,854 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX41,893,045 - 41,906,403 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX16,268,784 - 16,283,655 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X42,029,500 - 42,044,373 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX42,029,896 - 42,044,791 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X42,015,581 - 42,030,444 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X42,004,019 - 42,018,890 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X42,097,738 - 42,112,604 (+)NCBIUU_Cfam_GSD_1.0
Suv39h1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X34,406,375 - 34,420,755 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936721646,772 - 661,091 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936721646,778 - 661,144 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SUV39H1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX42,797,828 - 42,811,461 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X42,797,309 - 42,811,457 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SUV39H1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X45,820,114 - 45,834,727 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX45,822,453 - 45,834,917 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607611,300,493 - 11,313,955 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000010730   ⟹   ENSHGLP00000010611
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624893498,973 - 512,443 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000010731   ⟹   ENSHGLP00000010612
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624893499,396 - 504,823 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000010732   ⟹   ENSHGLP00000010613
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624893499,607 - 512,443 (+)Ensembl
RefSeq Acc Id: XM_004871950   ⟹   XP_004872007
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624893499,627 - 512,341 (+)NCBI
RefSeq Acc Id: XM_004871951   ⟹   XP_004872008
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624893499,222 - 512,341 (+)NCBI
RefSeq Acc Id: XM_013068237   ⟹   XP_012923691
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624893499,627 - 512,341 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004872007 (Get FASTA)   NCBI Sequence Viewer  
  XP_004872008 (Get FASTA)   NCBI Sequence Viewer  
  XP_012923691 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000010611
  ENSHGLP00000010613
GenBank Protein JAO01888 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004872008   ⟸   XM_004871951
- Peptide Label: isoform X3
- UniProtKB: A0A0P6JD86 (UniProtKB/TrEMBL),   G5BJH8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004872007   ⟸   XM_004871950
- Peptide Label: isoform X1
- UniProtKB: G5BJH8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012923691   ⟸   XM_013068237
- Peptide Label: isoform X2
- UniProtKB: G5BJH8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000010612   ⟸   ENSHGLT00000010731
Ensembl Acc Id: ENSHGLP00000010613   ⟸   ENSHGLT00000010732
Ensembl Acc Id: ENSHGLP00000010611   ⟸   ENSHGLT00000010730


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000007605 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000010730 ENTREZGENE
  ENSHGLT00000010732 ENTREZGENE
Gene3D-CATH 2.170.270.10 UniProtKB/TrEMBL
  2.40.50.40 UniProtKB/TrEMBL
InterPro Chromo-like_dom_sf UniProtKB/TrEMBL
  Chromo/chromo_shadow_dom UniProtKB/TrEMBL
  Chromo_domain UniProtKB/TrEMBL
  Chromodomain_CS UniProtKB/TrEMBL
  H3K9_Histone-Lys_N-MTase UniProtKB/TrEMBL
  Histone_H3-K9_MeTrfase UniProtKB/TrEMBL
  Post-SET_dom UniProtKB/TrEMBL
  Pre-SET_dom UniProtKB/TrEMBL
  SET_dom UniProtKB/TrEMBL
  SET_dom_sf UniProtKB/TrEMBL
NCBI Gene Suv39h1 ENTREZGENE
PANTHER HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H UniProtKB/TrEMBL
  HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H1 UniProtKB/TrEMBL
Pfam Chromo UniProtKB/TrEMBL
  Pre-SET UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
PIRSF SUV39_SET UniProtKB/TrEMBL
PROSITE CHROMO_1 UniProtKB/TrEMBL
  CHROMO_2 UniProtKB/TrEMBL
  POST_SET UniProtKB/TrEMBL
  PRE_SET UniProtKB/TrEMBL
  SAM_MT43_SUVAR39_3 UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
SMART CHROMO UniProtKB/TrEMBL
  PostSET UniProtKB/TrEMBL
  PreSET UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
Superfamily-SCOP SSF54160 UniProtKB/TrEMBL
  SSF82199 UniProtKB/TrEMBL
UniProt A0A0P6JD86 ENTREZGENE, UniProtKB/TrEMBL
  G5BJH8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-08-17 Suv39h1  SUV39H1 histone lysine methyltransferase  Suv39h1  suppressor of variegation 3-9 homolog 1  Symbol and/or name change 5135510 APPROVED