SUV39H2 (SUV39H2 histone lysine methyltransferase) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: SUV39H2 (SUV39H2 histone lysine methyltransferase) Sus scrofa
Analyze
Symbol: SUV39H2
Name: SUV39H2 histone lysine methyltransferase
RGD ID: 14222764
Description: ENCODES a protein that exhibits chromatin binding (ortholog); histone H3 methyltransferase activity (ortholog); histone H3K9me2 methyltransferase activity (ortholog); INVOLVED IN cellular response to hypoxia (ortholog); chromatin remodeling (ortholog); circadian rhythm (ortholog); PARTICIPATES IN histone modification pathway; methionine cycle/metabolic pathway; ASSOCIATED WITH genetic disease (ortholog); histiocytic sarcoma (ortholog); hypoparathyroidism-deafness-renal disease syndrome (ortholog); FOUND IN heterochromatin (ortholog); nucleus (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: histone-lysine N-methyltransferase SUV39H2; suppressor of variegation 3-9 homolog 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1046,873,126 - 46,900,040 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11046,874,606 - 46,900,058 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21051,595,641 - 51,633,086 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:15265077   PMID:22301074   PMID:23018532   PMID:30032202  


Genomics

Comparative Map Data
SUV39H2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1046,873,126 - 46,900,040 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11046,874,606 - 46,900,058 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21051,595,641 - 51,633,086 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SUV39H2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381014,878,866 - 14,904,315 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1014,878,820 - 14,904,315 (+)EnsemblGRCh38hg38GRCh38
GRCh371014,920,865 - 14,946,314 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361014,960,905 - 14,986,320 (+)NCBINCBI36Build 36hg18NCBI36
Build 341014,960,904 - 14,986,308NCBI
Celera1014,848,822 - 14,874,354 (+)NCBICelera
Cytogenetic Map10p13NCBI
HuRef1014,831,341 - 14,856,796 (+)NCBIHuRef
CHM1_11014,921,216 - 14,946,434 (+)NCBICHM1_1
T2T-CHM13v2.01014,892,831 - 14,918,279 (+)NCBIT2T-CHM13v2.0
Suv39h2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3923,456,852 - 3,476,085 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl23,456,852 - 3,476,068 (-)EnsemblGRCm39 Ensembl
GRCm3823,455,815 - 3,474,986 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl23,455,815 - 3,475,031 (-)EnsemblGRCm38mm10GRCm38
MGSCv3723,373,087 - 3,392,258 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3623,373,092 - 3,392,235 (-)NCBIMGSCv36mm8
Celera23,406,803 - 3,425,973 (-)NCBICelera
Cytogenetic Map2A1NCBI
cM Map21.95NCBI
Suv39h2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81779,665,467 - 79,684,492 (+)NCBIGRCr8
mRatBN7.21774,756,290 - 74,775,332 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1774,756,306 - 74,775,332 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1778,209,501 - 78,228,542 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01782,057,802 - 82,076,828 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01776,092,937 - 76,111,981 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01778,762,897 - 78,782,016 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1778,762,991 - 78,782,016 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01780,406,940 - 80,425,965 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41785,875,954 - 85,894,979 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11785,886,805 - 85,903,145 (+)NCBI
Celera1774,141,962 - 74,160,987 (+)NCBICelera
Cytogenetic Map17q12.3NCBI
Suv39h2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542919,503,197 - 19,528,027 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542919,503,197 - 19,526,454 (-)NCBIChiLan1.0ChiLan1.0
SUV39H2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2827,404,606 - 27,429,895 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11027,409,940 - 27,435,229 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01014,882,491 - 14,907,724 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11015,211,360 - 15,236,272 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1015,211,360 - 15,237,097 (+)Ensemblpanpan1.1panPan2
SUV39H2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1221,715,677 - 21,749,732 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl221,728,964 - 21,749,597 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha218,828,959 - 18,863,033 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0222,017,081 - 22,051,385 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl222,029,347 - 22,051,353 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1219,228,679 - 19,251,776 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0220,052,418 - 20,086,507 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0220,679,024 - 20,713,098 (-)NCBIUU_Cfam_GSD_1.0
Suv39h2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093446,893,110 - 6,922,105 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366131,443,629 - 1,467,229 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366131,443,663 - 1,467,776 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SUV39H2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1914,900,503 - 14,924,017 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl914,900,945 - 14,923,447 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605120,439,417 - 20,464,204 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Suv39h2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624805597,406 - 618,969 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624805594,986 - 619,115 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SUV39H2
529 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 10 4 3 5 2 23 2 3 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000012092   ⟹   ENSSSCP00000011784
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1046,862,584 - 46,899,966 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000049142   ⟹   ENSSSCP00000055161
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1046,873,126 - 46,900,040 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000059014   ⟹   ENSSSCP00000039480
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1046,875,128 - 46,899,966 (-)Ensembl
RefSeq Acc Id: NM_001039747   ⟹   NP_001034836
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11046,876,462 - 46,899,893 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005668113   ⟹   XP_005668170
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11046,874,606 - 46,900,058 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005668119   ⟹   XP_005668176
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11046,875,693 - 46,899,649 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013980236   ⟹   XP_013835690
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11046,875,693 - 46,899,572 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005668170   ⟸   XM_005668113
- Peptide Label: isoform X1
- UniProtKB: A0A287A6I1 (UniProtKB/TrEMBL),   A0A8D0NXY6 (UniProtKB/TrEMBL),   A0A8D0JMG2 (UniProtKB/TrEMBL),   C3RZ96 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005668176   ⟸   XM_005668119
- Peptide Label: isoform X2
- UniProtKB: Q27I49 (UniProtKB/TrEMBL),   A0A8D0WCK3 (UniProtKB/TrEMBL),   F1RW84 (UniProtKB/TrEMBL),   A0A8D0JMG2 (UniProtKB/TrEMBL),   C3RZ96 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013835690   ⟸   XM_013980236
- Peptide Label: isoform X2
- UniProtKB: Q27I49 (UniProtKB/TrEMBL),   A0A8D0WCK3 (UniProtKB/TrEMBL),   F1RW84 (UniProtKB/TrEMBL),   A0A8D0JMG2 (UniProtKB/TrEMBL),   C3RZ96 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001034836   ⟸   NM_001039747
- UniProtKB: Q27I49 (UniProtKB/TrEMBL),   A0A8D0WCK3 (UniProtKB/TrEMBL),   F1RW84 (UniProtKB/TrEMBL),   A0A8D0JMG2 (UniProtKB/TrEMBL),   C3RZ96 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000055161   ⟸   ENSSSCT00000049142
RefSeq Acc Id: ENSSSCP00000039480   ⟸   ENSSSCT00000059014
RefSeq Acc Id: ENSSSCP00000011784   ⟸   ENSSSCT00000012092
Protein Domains
Chromo   Post-SET   Pre-SET   SET


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000011048 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005030821 UniProtKB/TrEMBL
  ENSSSCG00015043397 UniProtKB/TrEMBL
  ENSSSCG00025034107 UniProtKB/TrEMBL
  ENSSSCG00030028361 UniProtKB/TrEMBL
  ENSSSCG00035038102 UniProtKB/TrEMBL
  ENSSSCG00040024258 UniProtKB/TrEMBL
  ENSSSCG00045035848 UniProtKB/TrEMBL
  ENSSSCG00050003023 UniProtKB/TrEMBL
  ENSSSCG00055003126 UniProtKB/TrEMBL
  ENSSSCG00060058855 UniProtKB/TrEMBL
  ENSSSCG00065018952 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000049142 ENTREZGENE
  ENSSSCT00000049142.2 UniProtKB/TrEMBL
  ENSSSCT00000059014 ENTREZGENE
  ENSSSCT00000059014.3 UniProtKB/TrEMBL
  ENSSSCT00005049252.1 UniProtKB/TrEMBL
  ENSSSCT00015057927.1 UniProtKB/TrEMBL
  ENSSSCT00015058251.1 UniProtKB/TrEMBL
  ENSSSCT00025046543.1 UniProtKB/TrEMBL
  ENSSSCT00025046629.1 UniProtKB/TrEMBL
  ENSSSCT00030039691.1 UniProtKB/TrEMBL
  ENSSSCT00030039706.1 UniProtKB/TrEMBL
  ENSSSCT00035050549.1 UniProtKB/TrEMBL
  ENSSSCT00035050561.1 UniProtKB/TrEMBL
  ENSSSCT00040032489.1 UniProtKB/TrEMBL
  ENSSSCT00040032551.1 UniProtKB/TrEMBL
  ENSSSCT00045061560.1 UniProtKB/TrEMBL
  ENSSSCT00045061640.1 UniProtKB/TrEMBL
  ENSSSCT00050003930.1 UniProtKB/TrEMBL
  ENSSSCT00050003944.1 UniProtKB/TrEMBL
  ENSSSCT00055006057.1 UniProtKB/TrEMBL
  ENSSSCT00055006082.1 UniProtKB/TrEMBL
  ENSSSCT00060080271.1 UniProtKB/TrEMBL
  ENSSSCT00060080316.1 UniProtKB/TrEMBL
  ENSSSCT00065025205.1 UniProtKB/TrEMBL
  ENSSSCT00065025222.1 UniProtKB/TrEMBL
Gene3D-CATH 2.170.270.10 UniProtKB/TrEMBL
  2.40.50.40 UniProtKB/TrEMBL
InterPro Chromo-like_dom_sf UniProtKB/TrEMBL
  Chromo/chromo_shadow_dom UniProtKB/TrEMBL
  Chromo_domain UniProtKB/TrEMBL
  Chromodomain_CS UniProtKB/TrEMBL
  Histone_H3-K9_MeTrfase UniProtKB/TrEMBL
  Post-SET_dom UniProtKB/TrEMBL
  Pre-SET_dom UniProtKB/TrEMBL
  SET_dom UniProtKB/TrEMBL
  SET_dom_sf UniProtKB/TrEMBL
KEGG Report ssc:664651 UniProtKB/TrEMBL
NCBI Gene SUV39H2 ENTREZGENE
PANTHER HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H UniProtKB/TrEMBL
  HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H2 UniProtKB/TrEMBL
Pfam Chromo UniProtKB/TrEMBL
  Pre-SET UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
PIRSF SUV39_SET UniProtKB/TrEMBL
PROSITE CHROMO_1 UniProtKB/TrEMBL
  CHROMO_2 UniProtKB/TrEMBL
  POST_SET UniProtKB/TrEMBL
  PRE_SET UniProtKB/TrEMBL
  SAM_MT43_SUVAR39_3 UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
SMART CHROMO UniProtKB/TrEMBL
  PostSET UniProtKB/TrEMBL
  PreSET UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
Superfamily-SCOP SSF54160 UniProtKB/TrEMBL
  SSF82199 UniProtKB/TrEMBL
UniProt A0A287A6I1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0JMG2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0NXY6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0WCK3 ENTREZGENE, UniProtKB/TrEMBL
  C3RZ96 ENTREZGENE, UniProtKB/TrEMBL
  F1RW84 ENTREZGENE
  Q27I49 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary F1RW84 UniProtKB/TrEMBL
VGNC ID VGNC:95841 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-08-16 SUV39H2  SUV39H2 histone lysine methyltransferase  SUV39H2  suppressor of variegation 3-9 homolog 2  Symbol and/or name change 19259463 PROVISIONAL