SUV39H2 (SUV39H2 histone lysine methyltransferase) - Rat Genome Database

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Gene: SUV39H2 (SUV39H2 histone lysine methyltransferase) Sus scrofa
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Symbol: SUV39H2
Name: SUV39H2 histone lysine methyltransferase
RGD ID: 14222764
Description: ENCODES a protein that exhibits chromatin binding (ortholog); histone H3 methyltransferase activity (ortholog); histone H3K9me2 methyltransferase activity (ortholog); INVOLVED IN cellular response to hypoxia (ortholog); chromatin remodeling (ortholog); circadian rhythm (ortholog); PARTICIPATES IN histone modification pathway; methionine cycle/metabolic pathway; ASSOCIATED WITH histiocytic sarcoma (ortholog); hypoparathyroidism-deafness-renal disease syndrome (ortholog); Parakeratosis (ortholog); FOUND IN heterochromatin (ortholog); nucleus (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: histone-lysine N-methyltransferase SUV39H2; suppressor of variegation 3-9 homolog 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1046,873,126 - 46,900,040 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11046,874,606 - 46,900,058 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21051,595,641 - 51,633,086 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:15265077   PMID:22301074   PMID:23018532   PMID:30032202  


Genomics

Comparative Map Data
SUV39H2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1046,873,126 - 46,900,040 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11046,874,606 - 46,900,058 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21051,595,641 - 51,633,086 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SUV39H2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381014,878,866 - 14,904,315 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1014,878,820 - 14,904,315 (+)EnsemblGRCh38hg38GRCh38
GRCh371014,920,865 - 14,946,314 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361014,960,905 - 14,986,320 (+)NCBINCBI36Build 36hg18NCBI36
Build 341014,960,904 - 14,986,308NCBI
Celera1014,848,822 - 14,874,354 (+)NCBICelera
Cytogenetic Map10p13NCBI
HuRef1014,831,341 - 14,856,796 (+)NCBIHuRef
CHM1_11014,921,216 - 14,946,434 (+)NCBICHM1_1
T2T-CHM13v2.01014,892,831 - 14,918,279 (+)NCBIT2T-CHM13v2.0
Suv39h2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3923,456,852 - 3,476,085 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl23,456,852 - 3,476,068 (-)EnsemblGRCm39 Ensembl
GRCm3823,455,815 - 3,474,986 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl23,455,815 - 3,475,031 (-)EnsemblGRCm38mm10GRCm38
MGSCv3723,373,087 - 3,392,258 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3623,373,092 - 3,392,235 (-)NCBIMGSCv36mm8
Celera23,406,803 - 3,425,973 (-)NCBICelera
Cytogenetic Map2A1NCBI
cM Map21.95NCBI
Suv39h2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81779,665,467 - 79,684,492 (+)NCBIGRCr8
mRatBN7.21774,756,290 - 74,775,332 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1774,756,306 - 74,775,332 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1778,209,501 - 78,228,542 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01782,057,802 - 82,076,828 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01776,092,937 - 76,111,981 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01778,762,897 - 78,782,016 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1778,762,991 - 78,782,016 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01780,406,940 - 80,425,965 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41785,875,954 - 85,894,979 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11785,886,805 - 85,903,145 (+)NCBI
Celera1774,141,962 - 74,160,987 (+)NCBICelera
Cytogenetic Map17q12.3NCBI
Suv39h2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542919,503,197 - 19,528,027 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542919,503,197 - 19,526,454 (-)NCBIChiLan1.0ChiLan1.0
SUV39H2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2827,404,606 - 27,429,895 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11027,409,940 - 27,435,229 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01014,882,491 - 14,907,724 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11015,211,360 - 15,236,272 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1015,211,360 - 15,237,097 (+)Ensemblpanpan1.1panPan2
SUV39H2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1221,715,677 - 21,749,732 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl221,728,964 - 21,749,597 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha218,828,959 - 18,863,033 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0222,017,081 - 22,051,385 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl222,029,347 - 22,051,353 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1219,228,679 - 19,251,776 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0220,052,418 - 20,086,507 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0220,679,024 - 20,713,098 (-)NCBIUU_Cfam_GSD_1.0
Suv39h2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093446,893,110 - 6,922,105 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366131,443,629 - 1,467,229 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366131,443,663 - 1,467,776 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SUV39H2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1914,900,503 - 14,924,017 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl914,900,945 - 14,923,447 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605120,439,417 - 20,464,204 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Suv39h2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624805597,406 - 618,969 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624805594,986 - 619,115 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SUV39H2
529 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000012092   ⟹   ENSSSCP00000011784
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1046,862,584 - 46,899,966 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000049142   ⟹   ENSSSCP00000055161
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1046,873,126 - 46,900,040 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000059014   ⟹   ENSSSCP00000039480
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1046,875,128 - 46,899,966 (-)Ensembl
RefSeq Acc Id: NM_001039747   ⟹   NP_001034836
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11046,876,462 - 46,899,893 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005668113   ⟹   XP_005668170
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11046,874,606 - 46,900,058 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005668119   ⟹   XP_005668176
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11046,875,693 - 46,899,649 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013980236   ⟹   XP_013835690
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11046,875,693 - 46,899,572 (-)NCBI
Sequence:
RefSeq Acc Id: XP_005668170   ⟸   XM_005668113
- Peptide Label: isoform X1
- UniProtKB: A0A287A6I1 (UniProtKB/TrEMBL),   A0A8D0NXY6 (UniProtKB/TrEMBL),   A0A8D0JMG2 (UniProtKB/TrEMBL),   C3RZ96 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005668176   ⟸   XM_005668119
- Peptide Label: isoform X2
- UniProtKB: Q27I49 (UniProtKB/TrEMBL),   A0A8D0WCK3 (UniProtKB/TrEMBL),   F1RW84 (UniProtKB/TrEMBL),   A0A8D0JMG2 (UniProtKB/TrEMBL),   C3RZ96 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013835690   ⟸   XM_013980236
- Peptide Label: isoform X2
- UniProtKB: Q27I49 (UniProtKB/TrEMBL),   A0A8D0WCK3 (UniProtKB/TrEMBL),   F1RW84 (UniProtKB/TrEMBL),   A0A8D0JMG2 (UniProtKB/TrEMBL),   C3RZ96 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001034836   ⟸   NM_001039747
- UniProtKB: Q27I49 (UniProtKB/TrEMBL),   A0A8D0WCK3 (UniProtKB/TrEMBL),   F1RW84 (UniProtKB/TrEMBL),   A0A8D0JMG2 (UniProtKB/TrEMBL),   C3RZ96 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000055161   ⟸   ENSSSCT00000049142
Ensembl Acc Id: ENSSSCP00000039480   ⟸   ENSSSCT00000059014
Ensembl Acc Id: ENSSSCP00000011784   ⟸   ENSSSCT00000012092
Protein Domains
Chromo   Post-SET   Pre-SET   SET


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000011048 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005030821 UniProtKB/TrEMBL
  ENSSSCG00015043397 UniProtKB/TrEMBL
  ENSSSCG00025034107 UniProtKB/TrEMBL
  ENSSSCG00030028361 UniProtKB/TrEMBL
  ENSSSCG00035038102 UniProtKB/TrEMBL
  ENSSSCG00040024258 UniProtKB/TrEMBL
  ENSSSCG00045035848 UniProtKB/TrEMBL
  ENSSSCG00050003023 UniProtKB/TrEMBL
  ENSSSCG00055003126 UniProtKB/TrEMBL
  ENSSSCG00060058855 UniProtKB/TrEMBL
  ENSSSCG00065018952 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000049142 ENTREZGENE
  ENSSSCT00000049142.2 UniProtKB/TrEMBL
  ENSSSCT00000059014 ENTREZGENE
  ENSSSCT00000059014.3 UniProtKB/TrEMBL
  ENSSSCT00005049252.1 UniProtKB/TrEMBL
  ENSSSCT00015057927.1 UniProtKB/TrEMBL
  ENSSSCT00015058251.1 UniProtKB/TrEMBL
  ENSSSCT00025046543.1 UniProtKB/TrEMBL
  ENSSSCT00025046629.1 UniProtKB/TrEMBL
  ENSSSCT00030039691.1 UniProtKB/TrEMBL
  ENSSSCT00030039706.1 UniProtKB/TrEMBL
  ENSSSCT00035050549.1 UniProtKB/TrEMBL
  ENSSSCT00035050561.1 UniProtKB/TrEMBL
  ENSSSCT00040032489.1 UniProtKB/TrEMBL
  ENSSSCT00040032551.1 UniProtKB/TrEMBL
  ENSSSCT00045061560.1 UniProtKB/TrEMBL
  ENSSSCT00045061640.1 UniProtKB/TrEMBL
  ENSSSCT00050003930.1 UniProtKB/TrEMBL
  ENSSSCT00050003944.1 UniProtKB/TrEMBL
  ENSSSCT00055006057.1 UniProtKB/TrEMBL
  ENSSSCT00055006082.1 UniProtKB/TrEMBL
  ENSSSCT00060080271.1 UniProtKB/TrEMBL
  ENSSSCT00060080316.1 UniProtKB/TrEMBL
  ENSSSCT00065025205.1 UniProtKB/TrEMBL
  ENSSSCT00065025222.1 UniProtKB/TrEMBL
Gene3D-CATH 2.170.270.10 UniProtKB/TrEMBL
  2.40.50.40 UniProtKB/TrEMBL
InterPro Chromo-like_dom_sf UniProtKB/TrEMBL
  Chromo/chromo_shadow_dom UniProtKB/TrEMBL
  Chromo_domain UniProtKB/TrEMBL
  Chromodomain_CS UniProtKB/TrEMBL
  H3K9_Histone-Lys_N-MTase UniProtKB/TrEMBL
  Histone_H3-K9_MeTrfase UniProtKB/TrEMBL
  Post-SET_dom UniProtKB/TrEMBL
  Pre-SET_dom UniProtKB/TrEMBL
  SET_dom UniProtKB/TrEMBL
  SET_dom_sf UniProtKB/TrEMBL
KEGG Report ssc:664651 UniProtKB/TrEMBL
NCBI Gene SUV39H2 ENTREZGENE
PANTHER HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H UniProtKB/TrEMBL
  HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H2 UniProtKB/TrEMBL
Pfam Chromo UniProtKB/TrEMBL
  Pre-SET UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
PIRSF SUV39_SET UniProtKB/TrEMBL
PROSITE CHROMO_1 UniProtKB/TrEMBL
  CHROMO_2 UniProtKB/TrEMBL
  POST_SET UniProtKB/TrEMBL
  PRE_SET UniProtKB/TrEMBL
  SAM_MT43_SUVAR39_3 UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
SMART CHROMO UniProtKB/TrEMBL
  PostSET UniProtKB/TrEMBL
  PreSET UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
Superfamily-SCOP SSF54160 UniProtKB/TrEMBL
  SSF82199 UniProtKB/TrEMBL
UniProt A0A287A6I1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0JMG2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0NXY6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0WCK3 ENTREZGENE, UniProtKB/TrEMBL
  C3RZ96 ENTREZGENE, UniProtKB/TrEMBL
  F1RW84 ENTREZGENE
  Q27I49 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary F1RW84 UniProtKB/TrEMBL
VGNC ID VGNC:95841 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-08-16 SUV39H2  SUV39H2 histone lysine methyltransferase  SUV39H2  suppressor of variegation 3-9 homolog 2  Symbol and/or name change 19259463 PROVISIONAL