SETDB1 (SET domain bifurcated histone lysine methyltransferase 1) - Rat Genome Database

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Gene: SETDB1 (SET domain bifurcated histone lysine methyltransferase 1) Canis lupus familiaris
Analyze
Symbol: SETDB1
Name: SET domain bifurcated histone lysine methyltransferase 1
RGD ID: 12376325
Description: ENCODES a protein that exhibits chromatin binding (ortholog); histone H3K9 trimethyltransferase activity (ortholog); promoter-specific chromatin binding (ortholog); INVOLVED IN bone development (ortholog); inner cell mass cell proliferation (ortholog); negative regulation of single stranded viral RNA replication via double stranded DNA intermediate (ortholog); PARTICIPATES IN histone modification pathway; homocysteine metabolic pathway; methionine cycle/metabolic pathway; ASSOCIATED WITH autistic disorder (ortholog); gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: histone-lysine N-methyltransferase SETDB1; SET domain bifurcated 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11760,035,819 - 60,069,721 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1760,037,379 - 60,069,551 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1759,481,019 - 59,513,690 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01761,052,838 - 61,085,686 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1761,052,909 - 61,085,961 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11759,881,637 - 59,914,607 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01759,966,210 - 59,999,560 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01760,694,148 - 60,726,997 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SETDB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11760,035,819 - 60,069,721 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1760,037,379 - 60,069,551 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1759,481,019 - 59,513,690 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01761,052,838 - 61,085,686 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1761,052,909 - 61,085,961 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11759,881,637 - 59,914,607 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01759,966,210 - 59,999,560 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01760,694,148 - 60,726,997 (+)NCBIUU_Cfam_GSD_1.0
SETDB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381150,926,263 - 150,964,737 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1150,926,263 - 150,964,744 (+)EnsemblGRCh38hg38GRCh38
GRCh371150,898,739 - 150,937,213 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361149,165,512 - 149,203,837 (+)NCBINCBI36Build 36hg18NCBI36
Build 341147,711,960 - 147,750,284NCBI
Celera1124,014,522 - 124,052,915 (+)NCBICelera
Cytogenetic Map1q21.3NCBI
HuRef1122,275,918 - 122,314,348 (+)NCBIHuRef
CHM1_11152,294,142 - 152,332,540 (+)NCBICHM1_1
T2T-CHM13v2.01150,049,948 - 150,088,436 (+)NCBIT2T-CHM13v2.0
Setdb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39395,230,836 - 95,264,513 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl395,230,836 - 95,264,513 (-)EnsemblGRCm39 Ensembl
GRCm38395,323,525 - 95,357,202 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl395,323,525 - 95,357,202 (-)EnsemblGRCm38mm10GRCm38
MGSCv37395,127,447 - 95,161,124 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36395,408,929 - 95,442,577 (-)NCBIMGSCv36mm8
Celera396,754,826 - 96,788,575 (-)NCBICelera
Cytogenetic Map3F2.1NCBI
cM Map340.74NCBI
Setdb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82185,587,722 - 185,619,084 (-)NCBIGRCr8
mRatBN7.22182,898,738 - 182,930,283 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2182,898,738 - 182,930,506 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2190,563,824 - 190,594,782 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02188,359,310 - 188,390,238 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02183,196,321 - 183,227,279 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02196,495,867 - 196,527,412 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2196,495,867 - 196,527,127 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02215,994,295 - 216,025,842 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42190,232,228 - 190,264,309 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12190,195,015 - 190,227,043 (-)NCBI
Celera2175,432,236 - 175,463,195 (-)NCBICelera
Cytogenetic Map2q34NCBI
Setdb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955588290,168 - 338,426 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955588290,497 - 338,438 (+)NCBIChiLan1.0ChiLan1.0
SETDB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2198,868,713 - 98,907,047 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1198,622,938 - 98,661,286 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01126,275,719 - 126,314,043 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11129,925,009 - 129,962,442 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1129,925,009 - 129,962,442 (+)Ensemblpanpan1.1panPan2
Setdb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505822,115,903 - 22,162,583 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365801,146,277 - 1,192,842 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365801,146,286 - 1,192,842 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SETDB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl498,260,375 - 98,293,097 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1498,259,801 - 98,293,238 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24107,514,914 - 107,547,700 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SETDB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366603812,316,851 - 12,357,421 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Setdb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477218,855,332 - 18,894,226 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477218,855,405 - 18,894,285 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SETDB1
424 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 1 16 4 6 11 8 10 1
Low 4 5 6 6 2 6 6 1 5
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005630771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005630772 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022404972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022404973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038423081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038423082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038423083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038423084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038423085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038453196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038499578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038499579 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038499580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038499581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038499582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038562146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038562147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038562148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038562149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038562150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038626243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038626244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038626245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038626246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038626247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000036155   ⟹   ENSCAFP00000031500
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1760,037,379 - 60,069,264 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000045593   ⟹   ENSCAFP00000037492
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1760,037,379 - 60,069,264 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000049297   ⟹   ENSCAFP00000041684
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1760,037,379 - 60,069,551 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845035663   ⟹   ENSCAFP00845027903
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1761,052,909 - 61,085,961 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845035820   ⟹   ENSCAFP00845028025
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1761,052,909 - 61,085,961 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845035907   ⟹   ENSCAFP00845028099
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1761,052,909 - 61,069,657 (+)Ensembl
RefSeq Acc Id: XM_005630771   ⟹   XP_005630828
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11760,035,917 - 60,069,721 (+)NCBI
Dog10K_Boxer_Tasha1759,481,147 - 59,513,690 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005630772   ⟹   XP_005630829
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11760,035,819 - 60,069,721 (+)NCBI
Dog10K_Boxer_Tasha1759,481,019 - 59,513,690 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022404972   ⟹   XP_022260680
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11760,036,262 - 60,069,721 (+)NCBI
Dog10K_Boxer_Tasha1759,481,483 - 59,513,690 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022404973   ⟹   XP_022260681
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11760,036,262 - 60,069,721 (+)NCBI
Dog10K_Boxer_Tasha1759,481,483 - 59,513,690 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038423081   ⟹   XP_038279009
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01761,053,302 - 61,085,686 (+)NCBI
RefSeq Acc Id: XM_038423082   ⟹   XP_038279010
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01761,053,302 - 61,085,686 (+)NCBI
RefSeq Acc Id: XM_038423083   ⟹   XP_038279011
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01761,052,966 - 61,085,686 (+)NCBI
RefSeq Acc Id: XM_038423084   ⟹   XP_038279012
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01761,052,838 - 61,085,686 (+)NCBI
RefSeq Acc Id: XM_038423085   ⟹   XP_038279013
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01761,053,302 - 61,085,686 (+)NCBI
RefSeq Acc Id: XM_038453196   ⟹   XP_038309124
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1759,481,483 - 59,513,690 (+)NCBI
RefSeq Acc Id: XM_038499578   ⟹   XP_038355506
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11759,882,101 - 59,914,607 (+)NCBI
RefSeq Acc Id: XM_038499579   ⟹   XP_038355507
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11759,882,101 - 59,914,607 (+)NCBI
RefSeq Acc Id: XM_038499580   ⟹   XP_038355508
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11759,881,765 - 59,914,607 (+)NCBI
RefSeq Acc Id: XM_038499581   ⟹   XP_038355509
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11759,881,637 - 59,914,607 (+)NCBI
RefSeq Acc Id: XM_038499582   ⟹   XP_038355510
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11759,882,101 - 59,914,607 (+)NCBI
RefSeq Acc Id: XM_038562146   ⟹   XP_038418074
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01760,694,612 - 60,726,997 (+)NCBI
RefSeq Acc Id: XM_038562147   ⟹   XP_038418075
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01760,694,612 - 60,726,997 (+)NCBI
RefSeq Acc Id: XM_038562148   ⟹   XP_038418076
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01760,694,276 - 60,726,997 (+)NCBI
RefSeq Acc Id: XM_038562149   ⟹   XP_038418077
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01760,694,148 - 60,726,997 (+)NCBI
RefSeq Acc Id: XM_038562150   ⟹   XP_038418078
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01760,694,612 - 60,726,997 (+)NCBI
RefSeq Acc Id: XM_038626243   ⟹   XP_038482171
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01759,966,674 - 59,999,560 (+)NCBI
RefSeq Acc Id: XM_038626244   ⟹   XP_038482172
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01759,966,674 - 59,999,560 (+)NCBI
RefSeq Acc Id: XM_038626245   ⟹   XP_038482173
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01759,966,338 - 59,999,560 (+)NCBI
RefSeq Acc Id: XM_038626246   ⟹   XP_038482174
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01759,966,210 - 59,999,560 (+)NCBI
RefSeq Acc Id: XM_038626247   ⟹   XP_038482175
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01759,966,674 - 59,999,560 (+)NCBI
Protein Sequences
Protein RefSeqs XP_005630828 (Get FASTA)   NCBI Sequence Viewer  
  XP_005630829 (Get FASTA)   NCBI Sequence Viewer  
  XP_022260680 (Get FASTA)   NCBI Sequence Viewer  
  XP_022260681 (Get FASTA)   NCBI Sequence Viewer  
  XP_038279009 (Get FASTA)   NCBI Sequence Viewer  
  XP_038279010 (Get FASTA)   NCBI Sequence Viewer  
  XP_038279011 (Get FASTA)   NCBI Sequence Viewer  
  XP_038279012 (Get FASTA)   NCBI Sequence Viewer  
  XP_038279013 (Get FASTA)   NCBI Sequence Viewer  
  XP_038309124 (Get FASTA)   NCBI Sequence Viewer  
  XP_038355506 (Get FASTA)   NCBI Sequence Viewer  
  XP_038355507 (Get FASTA)   NCBI Sequence Viewer  
  XP_038355508 (Get FASTA)   NCBI Sequence Viewer  
  XP_038355509 (Get FASTA)   NCBI Sequence Viewer  
  XP_038355510 (Get FASTA)   NCBI Sequence Viewer  
  XP_038418074 (Get FASTA)   NCBI Sequence Viewer  
  XP_038418075 (Get FASTA)   NCBI Sequence Viewer  
  XP_038418076 (Get FASTA)   NCBI Sequence Viewer  
  XP_038418077 (Get FASTA)   NCBI Sequence Viewer  
  XP_038418078 (Get FASTA)   NCBI Sequence Viewer  
  XP_038482171 (Get FASTA)   NCBI Sequence Viewer  
  XP_038482172 (Get FASTA)   NCBI Sequence Viewer  
  XP_038482173 (Get FASTA)   NCBI Sequence Viewer  
  XP_038482174 (Get FASTA)   NCBI Sequence Viewer  
  XP_038482175 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00000037492.2
  ENSCAFP00000041684.2
  ENSCAFP00030011108.1
  ENSCAFP00040019016.1
  ENSCAFP00845027903
  ENSCAFP00845027903.1
  ENSCAFP00845028025.1
  ENSCAFP00845028099.1
Reference Protein Sequences
RefSeq Acc Id: XP_005630829   ⟸   XM_005630772
- Peptide Label: isoform X3
- UniProtKB: A0A8C0R0Q2 (UniProtKB/TrEMBL),   A0A8C0SCA0 (UniProtKB/TrEMBL),   A0A8I3PJ60 (UniProtKB/TrEMBL),   A0A8C0KNR7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005630828   ⟸   XM_005630771
- Peptide Label: isoform X3
- UniProtKB: A0A8C0R0Q2 (UniProtKB/TrEMBL),   A0A8C0SCA0 (UniProtKB/TrEMBL),   A0A8I3PJ60 (UniProtKB/TrEMBL),   A0A8C0KNR7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022260680   ⟸   XM_022404972
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KNR7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022260681   ⟸   XM_022404973
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KNR7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000041684   ⟸   ENSCAFT00000049297
RefSeq Acc Id: ENSCAFP00000037492   ⟸   ENSCAFT00000045593
RefSeq Acc Id: ENSCAFP00000031500   ⟸   ENSCAFT00000036155
RefSeq Acc Id: XP_038355509   ⟸   XM_038499581
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038355508   ⟸   XM_038499580
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038355506   ⟸   XM_038499578
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038355510   ⟸   XM_038499582
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038355507   ⟸   XM_038499579
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038482174   ⟸   XM_038626246
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038482173   ⟸   XM_038626245
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038482171   ⟸   XM_038626243
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038482175   ⟸   XM_038626247
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038482172   ⟸   XM_038626244
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038279012   ⟸   XM_038423084
- Peptide Label: isoform X3
- UniProtKB: A0A8C0R0Q2 (UniProtKB/TrEMBL),   A0A8C0SCA0 (UniProtKB/TrEMBL),   A0A8I3PJ60 (UniProtKB/TrEMBL),   A0A8C0KNR7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038279011   ⟸   XM_038423083
- Peptide Label: isoform X3
- UniProtKB: A0A8C0R0Q2 (UniProtKB/TrEMBL),   A0A8C0SCA0 (UniProtKB/TrEMBL),   A0A8I3PJ60 (UniProtKB/TrEMBL),   A0A8C0KNR7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038279009   ⟸   XM_038423081
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KNR7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038279013   ⟸   XM_038423085
- Peptide Label: isoform X4
- UniProtKB: A0A8C0KNR7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038279010   ⟸   XM_038423082
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KNR7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038309124   ⟸   XM_038453196
- Peptide Label: isoform X4
- UniProtKB: A0A8C0KNR7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038418077   ⟸   XM_038562149
- Peptide Label: isoform X3
- UniProtKB: A0A8C0KNR7 (UniProtKB/TrEMBL),   A0A8C0R0Q2 (UniProtKB/TrEMBL),   A0A8C0SCA0 (UniProtKB/TrEMBL),   A0A8I3PJ60 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038418076   ⟸   XM_038562148
- Peptide Label: isoform X3
- UniProtKB: A0A8C0KNR7 (UniProtKB/TrEMBL),   A0A8C0R0Q2 (UniProtKB/TrEMBL),   A0A8C0SCA0 (UniProtKB/TrEMBL),   A0A8I3PJ60 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038418074   ⟸   XM_038562146
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KNR7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038418078   ⟸   XM_038562150
- Peptide Label: isoform X4
- UniProtKB: A0A8C0KNR7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038418075   ⟸   XM_038562147
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KNR7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845028099   ⟸   ENSCAFT00845035907
RefSeq Acc Id: ENSCAFP00845028025   ⟸   ENSCAFT00845035820
RefSeq Acc Id: ENSCAFP00845027903   ⟸   ENSCAFT00845035663
Protein Domains
DUF5604   MBD   Post-SET   Pre-SET   SET   Tudor

Promoters
RGD ID:13686396
Promoter ID:EPDNEW_C4463
Type:initiation region
Name:SETDB1_1
Description:SET domain bifurcated 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11760,035,963 - 60,036,023EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000023501 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030006901 UniProtKB/TrEMBL
  ENSCAFG00040011895 UniProtKB/TrEMBL
  ENSCAFG00845020216 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000045593.3 UniProtKB/TrEMBL
  ENSCAFT00000049297.4 UniProtKB/TrEMBL
  ENSCAFT00030012699.1 UniProtKB/TrEMBL
  ENSCAFT00040021919.1 UniProtKB/TrEMBL
  ENSCAFT00845035663 ENTREZGENE
  ENSCAFT00845035663.1 UniProtKB/TrEMBL
  ENSCAFT00845035820.1 UniProtKB/TrEMBL
  ENSCAFT00845035907.1 UniProtKB/TrEMBL
Gene3D-CATH 2.170.270.10 UniProtKB/TrEMBL
  2.30.30.140 UniProtKB/TrEMBL
InterPro DNA-bd_dom_sf UniProtKB/TrEMBL
  DUF5604 UniProtKB/TrEMBL
  Hist-Lys_N-MeTrfase_SETDB1 UniProtKB/TrEMBL
  Methyl_CpG_DNA-bd UniProtKB/TrEMBL
  Post-SET_dom UniProtKB/TrEMBL
  Pre-SET_dom UniProtKB/TrEMBL
  SET_dom UniProtKB/TrEMBL
  SET_dom_sf UniProtKB/TrEMBL
  SETDB1/2-like_MBD UniProtKB/TrEMBL
  Tudor UniProtKB/TrEMBL
  Tudor_4 UniProtKB/TrEMBL
  TUDOR_5 UniProtKB/TrEMBL
KEGG Report cfa:483186 UniProtKB/TrEMBL
NCBI Gene SETDB1 ENTREZGENE
PANTHER HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS UniProtKB/TrEMBL
  HISTONE-LYSINE N-METHYLTRANSFERASE SETDB1 UniProtKB/TrEMBL
Pfam DUF5604 UniProtKB/TrEMBL
  MBD UniProtKB/TrEMBL
  Pre-SET UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
  Tudor_4 UniProtKB/TrEMBL
  TUDOR_5 UniProtKB/TrEMBL
PROSITE MBD UniProtKB/TrEMBL
  POST_SET UniProtKB/TrEMBL
  PRE_SET UniProtKB/TrEMBL
  SAM_MT43_SUVAR39_1 UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
SMART MBD UniProtKB/TrEMBL
  PreSET UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
  TUDOR UniProtKB/TrEMBL
Superfamily-SCOP SSF54171 UniProtKB/TrEMBL
  SSF82199 UniProtKB/TrEMBL
UniProt A0A8C0KNR7 ENTREZGENE
  A0A8C0MJ63_CANLF UniProtKB/TrEMBL
  A0A8C0R0Q2 ENTREZGENE
  A0A8C0SCA0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PHI2_CANLF UniProtKB/TrEMBL
  A0A8I3PJ60 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3S4D3_CANLF UniProtKB/TrEMBL
  A0A8P0NPB8_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:46060 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-01-22 SETDB1  SET domain bifurcated histone lysine methyltransferase 1    SET domain bifurcated 1  Symbol and/or name change 5135510 APPROVED