Suv39h1 (SUV39H1 histone lysine methyltransferase)

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Gene: Suv39h1 (SUV39H1 histone lysine methyltransferase) Ictidomys tridecemlineatus

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Symbol:

Suv39h1

Name:

SUV39H1 histone lysine methyltransferase

RGD ID:

12580051

Description:

ENCODES a protein that exhibits histone H3K9me2 methyltransferase activity (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); transcription cis-regulatory region binding (ortholog); INVOLVED IN blastocyst hatching (ortholog); cellular response to hypoxia (ortholog); circadian rhythm (ortholog); PARTICIPATES IN histone modification pathway; methionine cycle/metabolic pathway; ASSOCIATED WITH autistic disorder (ortholog); Chromosome Breakage (ortholog); congenital disorder of glycosylation type IIm (ortholog); FOUND IN nucleolus (ortholog); nucleus (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

histone-lysine N-methyltransferase SUV39H1; suppressor of variegation 3-9 homolog 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	34,406,375 - 34,420,755 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936721	646,772 - 661,091 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936721	646,778 - 661,144 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

Chromosome Breakage (ISO)

congenital disorder of glycosylation type IIm (ISO)

Diamond-Blackfan anemia (ISO)

high grade glioma (ISO)

immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome (ISO)

Neoplastic Cell Transformation (ISO)

neurodegeneration with brain iron accumulation 5 (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

Thrombocytopenia 1 (ISO)

Wiskott-Aldrich syndrome (ISO)

X-linked epilepsy with variable learning disabilities and behavior disorders (ISO)

X-linked severe congenital neutropenia (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

blastocyst hatching (ISO)

cell differentiation (IEA)

cellular response to glucose starvation (IEA)

cellular response to hypoxia (IEA,ISO)

chromatin organization (IEA)

circadian rhythm (ISO)

determination of adult lifespan (ISO)

DNA damage response (IEA,ISO)

energy homeostasis (IEA)

epigenetic programming in the zygotic pronuclei (IEA)

methylation (IEA)

negative regulation of cell cycle (IEA)

negative regulation of DNA-templated transcription (IEA)

negative regulation of gene expression, epigenetic (ISO)

negative regulation of transcription by RNA polymerase II (IEA,ISO)

rDNA heterochromatin formation (IEA)

regulation of bone mineralization (ISO)

regulation of cellular senescence (ISO)

regulation of DNA repair (ISO)

regulation of multicellular organism growth (ISO)

regulation of transcription by glucose (IEA)

Cellular Component

chromatin silencing complex (IEA)

chromosome (IEA)

chromosome, centromeric region (IEA)

eNoSc complex (IEA)

heterochromatin (IEA)

nucleolus (IEA,ISO)

nucleus (IEA,ISO)

rDNA heterochromatin (IEA)

Molecular Function

histone H3K9 methyltransferase activity (IEA)

histone H3K9 trimethyltransferase activity (IEA)

histone H3K9me2 methyltransferase activity (ISO)

histone methyltransferase activity (IEA)

metal ion binding (IEA)

methyltransferase activity (IEA)

protein binding (ISO)

RNA polymerase II transcription regulatory region sequence-specific DNA binding (ISO)

S-adenosylmethionine-dependent methyltransferase activity (IEA)

transcription cis-regulatory region binding (ISO)

zinc ion binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

histone modification pathway (ISO)

methionine cycle/metabolic pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Suv39h1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	34,406,375 - 34,420,755 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936721	646,772 - 661,091 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936721	646,778 - 661,144 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SUV39H1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	48,695,554 - 48,709,016 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	48,695,554 - 48,709,016 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	48,553,945 - 48,567,407 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	48,440,075 - 48,452,351 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	48,311,380 - 48,323,651	NCBI
Celera	X	53,096,600 - 53,108,876 (-)	NCBI		Celera
Cytogenetic Map	X	p11.23	NCBI
HuRef	X	46,217,119 - 46,229,438 (+)	NCBI		HuRef
CHM1_1	X	48,586,299 - 48,598,575 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	48,106,035 - 48,119,497 (+)	NCBI		T2T-CHM13v2.0

Suv39h1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	7,927,401 - 7,940,994 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	7,927,410 - 7,940,999 (-)	Ensembl		GRCm39 Ensembl
GRCm38	X	8,061,171 - 8,074,760 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	8,061,171 - 8,074,760 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	7,638,297 - 7,651,886 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	7,218,263 - 7,231,545 (-)	NCBI		MGSCv36	mm8
Celera	X	3,394,838 - 3,408,427 (+)	NCBI		Celera
Cytogenetic Map	X	A1.1	NCBI
cM Map	X	3.64	NCBI

Suv39h1-ps1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	146,828,818 - 146,831,485 (-)	NCBI		GRCr8
mRatBN7.2	X	141,792,589 - 141,795,257 (-)	NCBI	mRatBN7.2	mRatBN7.2
UTH_Rnor_SHR_Utx	X	143,977,956 - 143,980,623 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	147,518,936 - 147,521,604 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	145,074,611 - 145,077,279 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	146,532,002 - 146,533,538 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	X	146,551,234 - 146,555,970 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	149,153,769 - 149,155,266 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	X	137,768,982 - 137,770,518 (-)	NCBI		Celera
Cytogenetic Map	X	q36	NCBI

Suv39h1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955543	258,479 - 272,473 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955543	258,479 - 271,128 (+)	NCBI	ChiLan1.0	ChiLan1.0

SUV39H1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	50,184,506 - 50,197,961 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	50,187,878 - 50,201,333 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	40,993,911 - 41,007,362 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	48,855,494 - 48,868,137 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	48,855,494 - 48,868,131 (+)	Ensembl	panpan1.1		panPan2

SUV39H1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	41,894,623 - 41,907,854 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	41,893,045 - 41,906,403 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	16,268,784 - 16,283,655 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	42,029,500 - 42,044,373 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	42,029,896 - 42,044,791 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	42,015,581 - 42,030,444 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	42,004,019 - 42,018,890 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	42,097,738 - 42,112,604 (+)	NCBI		UU_Cfam_GSD_1.0

SUV39H1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	42,797,828 - 42,811,461 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	42,797,309 - 42,811,457 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

SUV39H1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	45,820,114 - 45,834,727 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	45,822,453 - 45,834,917 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666076	11,300,493 - 11,313,955 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Suv39h1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624893	498,973 - 512,443 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624893	499,222 - 512,341 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005338653	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_002485520	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000614	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000015329 ⟹ ENSSTOP00000013735

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936721	646,772 - 661,091 (+)	Ensembl

RefSeq Acc Id:

XM_005338653 ⟹ XP_005338710

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	X	34,406,379 - 34,420,755 (+)	NCBI
SpeTri2.0	NW_004936721	646,778 - 661,144 (+)	NCBI

Sequence:

show sequence

CGGCGAGCACCCGCCTCCGGGACCGAGCCGGTGGTGGGGAGGGGTCCCGTCACGGCTCGCCGGT
TGGTCCGCGCGGGCGCTGCTGGCGGGGAGGCACGGCCAATAGGCTGCGCGTTCCCGGCCACGCC
CGCGCGAGCTCTCTTCTCGCGAGGCCGGCTAGGCCCGAATGTCGTTAGCCGTGGGGAAAGATGG
CGGAAAATTTAAAAGGCTGCAGTGTGTGTTGCAAGTCTTCTTGGAATCAGTTGCAGGATCTGTG
CCGCCTGGCCAAGCTGTCCTGCCCTGCCCTTGGCATCTCTAAGAGGAACCTCTATGATTTTGAA
GTCGAGTACCTGTGTGATTACAAGAAGATCCGAGAACAAGAATATTACCTGGTAAAGTGGCGTG
GATACCCTGACTCAGAGAGCACCTGGGAACCAAGGCAGAATCTCAAGTGTGTGCGCATTCTCAA
GCAGTTCCACAAGGACTTAGAAAAGGAGCTGCTCCGCCGGCATCACAGGTTGAAGCCACCCCGG
CATCTGGACCCAAGTTTGGCCAACTACCTCGTGCAGAAGGCCAAGCAGAGGCGGGCACTTCAGC
GCTGGGAGCAGGAGCTCAATGCCAAGCGCAGCCACCTAGGACGCATTACTGTGGAGAATGAGGT
GGACCTGGATGGCCCCCCACGGGCCTTCGTGTACATCAATGAATACCGTGTTGGTGAGGGTATC
ACCCTCAACCAGGTGGCCGTAGGCTGCGAGTGTCAGGACTGTCTATGGGCACCAGCTGGAGGCT
GCTGCCCTGGGGCATCCCTGCACAAGTTTGCCTACAATGACCAAGGCCAGGTGCGGCTGCGAGC
CGGGCTGCCCATCTATGAGTGCAACTCCCGCTGCCGCTGCGGCTATGACTGCCCCAACCGCGTA
GTACAGAAGGGCATCCGCTATGATCTCTGCATCTTCCGCACAGATGATGGGCGTGGCTGGGGTG
TACGCACTCTAGAGAAGATTCGCAAGAACAGCTTCGTCATGGAGTATGTGGGAGAGATCATTAC
CTCAGAGGAGGCGGAGCGGCGGGGCCAGATCTATGACCGTCAGGGTGCCACCTACCTCTTCGAC
CTGGACTACGTGGAGGACGTGTATACTGTGGATGCCGCCTATTATGGCAACATCTCCCACTTTG
TTAACCATAGTTGTGACCCCAACCTACAGGTGTACAACGTCTTCATAGACAACCTTGATGAGCG
GCTGCCCCGCATTGCTTTCTTTGCCACAAGAACCATCCGGGCAGGCGAGGAGCTCACCTTTGAT
TACAACATGCAAGTGGACCCCGTGGACATGGAGAGTACCCGTATGGACTCCAACTTTGGCCTGG
CTGGGCTCCCCGGCTCCCCCAAGAAGCGGGTCCGTATTGAATGCAAGTGTGGGACTGAATCCTG
CCGCAAATACCTCTTCTAGCCCTGAGAAGTTTGAGGCCAGACTGACTGAGGGGGGTCTGAAGCC
ACCTCCCCCTCCCCCACTCCTTCCCTCCTATAGGGGAATGACTGCCAGGGCCTCGCCTGCCTCC
ACCTGATCCCACTTGTCCCCTCTACCCCCCTCCCCCCCGCCTGCTCCACCTGCTCCACCTGCTC
CAGGGTCAGGGCTGCAGTGAGGACCAACTCCAGGAGTCCCCTTTCTCTGTCCCAGCTCCATCTG
TTGGTTGCACTTACAAACCCCTGCCCACCTTCAGAAGTACCTTTTCCCATCAGGATTTTCTGCA
GTTGGGATTTATGACCTATGAAGGAGGTCCAAGGGGTGAGCCCAGCCCCAGAACAGAAAGATGC
TTGTTTCTGCCTGGAGCCTGAGGGGTCTGCTGCAGGTCTCCTCCCTGTTGCCTCCGGGTGTCGG
GAAGCAACACTCCGGACAGGCAGACATCAGAGCCCAGAGTTTCCAGCATGACTTGAAGCTGGTT
CTCCAACCACAGAACCTTTATACTAGTGAAAGAAAAGGGGGTTTCCAGGGCAGGGTGCTAAGGC
TGGTTTTTGCCCATTGTGCTTATGATGCTTATGATGTTGGCCTTAAGAGTCATAGGATATCTGC
CAGGGCTTTACATCCGAGAAGTGGATGCCCATGGCCCACTGGCCAGTGAGAGGAAGGTGATCTA
TACTTTGCTAGCTCTGGCGGTGGCCAGGACTGAGTTCTACCTTCAGGGAACACAGAGAAGATGT
CCCAGGCTTTCAGGAACACTGAGTGTTAGGACTCCTGCCATGGAGTGTGATGATTGCTAGGACT
ACTCAGAGCTGGAATCAAGATCTAGATAGTCCTAGATAGCACTTAGGAGAATAATGTGCATTGA
TGGAAAGCTGATGAGGTGCATCTGGTCCACGTGGATTGTCTCAGGGAAGCCTTGAAAACCACAG
AGGTGGATCCCAGGAAAGGGCCTGTGTGGTAGAAGGCAAAGTAAAGGCCAAGAATTGGGGAAAA
CTTACCCACTAAGATACAGTAAGGCAAGAGAAAATCTACTTCCCACCAGCCTCAGCCTCCAGCC
CTTTGTGCTCACCTTGGGTCCACTGGTCTCCCAAATTGCCTACAAATGTACAAAAGGTGAAAGT
TCTGATGGCTGCCTCGCCCTGCTCCCCCACCCCTGTGAGGTCTTCTCTAGGAAACCTTTACTGA
CTACCTGTGCCCAGAGTGCCCCTATGTGAGACTGTGCACCCTGCTATCAGATCTATGTGTCTGT
CTATGTGTCTGTCCTGCCCTTGCCCCCAAGGCTGACCTTCAGGCATGGACTGAATGTGGTTCTC
CTCTTGTATACCCCTCAGCTCTACCCAGCCTGGAGTGGGCATCAATAAAATACATTGTTGACTG
AA

hide sequence

RefSeq Acc Id:

XR_002485520

Type:

NON-CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	X	34,406,375 - 34,419,369 (+)	NCBI
SpeTri2.0	NW_004936721	646,778 - 659,686 (+)	NCBI

Sequence:

show sequence

CGGCGAGCACCCGCCTCCGGGACCGAGCCGGTGGTGGGGAGGGGTCCCGTCACGGCTCGCCGGT
TGGTCCGCGCGGGCGCTGCTGGCGGGGAGGCACGGCCAATAGGCTGCGCGTTCCCGGCCACGCC
CGCGCGAGCTCTCTTCTCGCGAGGCCGGCTAGGCCCGAATGTCGTTAGCCGTGGGGAAAGATGG
CGGAAAATTTAAAAGGCTGCAGTGTGTGTTGCAAGTCTTCTTGGAATCAGTTGCAGGATCTGTG
CCGCCTGGCCAAGCTGTCCTGCCCTGCCCTTGGCATCTCTAAGAGGAACCTCTATGATTTTGAA
GTCGAGTACCTGTGTGATTACAAGAAGATCCGAGAACAAGAATATTACCTGGTAAAGTGGCGTG
GATACCCTGACTCAGAGAGCACCTGGGAACCAAGGCAGAATCTCAAGTGTGTGCGCATTCTCAA
GCAGTTCCACAAGGACTTAGAAAAGGAGCTGCTCCGCCGGCATCACAGGTTGAAGCCACCCCGG
CATCTGGACCCAAGTTTGGCCAACTACCTCGTGCAGAAGGCCAAGCAGAGGCGGGCACTTCAGC
GCTGGGAGCAGGAGCTCAATGCCAAGCGCAGCCACCTAGGACGCATTACTGTGGAGAATGAGGT
GGACCTGGATGGCCCCCCACGGGCCTTCGTGTACATCAATGAATACCGTGTTGGTGAGGGTATC
ACCCTCAACCAGGTGGCCGTAGGCTGCGAGTGTCAGGACTGTCTATGGGCACCAGCTGGAGGCT
GCTGCCCTGGGGCATCCCTGCACAAGTTTGCCTACAATGACCAAGGCCAGGTGCGGCTGCGAGC
CGGGCTGCCCATCTATGAGTGCAACTCCCGCTGCCGCTGCGGCTATGACTGCCCCAACCGCGTA
GTACAGAAGGGCATCCGCTATGATCTCTGCATCTTCCGCACAGATGATGGGCGTGGCTGGGGTG
TACGCACTCTAGAGAAGATTCGCAAGAACAGCTTCGTCATGGAGTATGTGGGAGAGATCATTAC
CTCAGAGGAGGCGGAGCGGCGGGGCCAGATCTATGACCGTCAGGGTGCCACCTACCTCTTCGAC
CTGGACTACGTGGAGGACGTGTATACTGTGGATGCCGCCTATTATGGCAACATCTCCCACTTTG
TTAACCATAGTTGTGACCCCAACCTACAGGTGTACAACGTCTTCATAGACAACCTTGATGAGCG
GCTGCCCCGCATTGCTTTCTTTGCCACAAGAACCATCCGGGCAGGCGAGGAGCTCACCTTTGAT
TACAACATGCAAGCCCCCTGTGACTTTCCTCAGTCCAGGCCTTTGGAAAACCAGTCCCTTCCTT
GATAGACTAGACATCTCTGAGATACTCAGTGTGGATCTGGGGCAGGATGCTTCTATGGATACAC
AGTGGACCCCGTGGACATGGAGAGTACCCGTATGGACTCCAACTTTGGCCTGGCTGGGCTCCCC
GGCTC

hide sequence

Protein Sequences


Protein RefSeqs	XP_005338710	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000013735.2
GenBank Protein	KAG3272067	(Get FASTA)	NCBI Sequence Viewer
	KAG3272068	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005338710 ⟸ XM_005338653

- UniProtKB:

I3MPK2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAENLKGCSVCCKSSWNQLQDLCRLAKLSCPALGISKRNLYDFEVEYLCDYKKIREQEYYLVKW
RGYPDSESTWEPRQNLKCVRILKQFHKDLEKELLRRHHRLKPPRHLDPSLANYLVQKAKQRRAL
QRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGEGITLNQVAVGCECQDCLWAPAG
GCCPGASLHKFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKGIRYDLCIFRTDDGRGW
GVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISH
FVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDSNFG
LAGLPGSPKKRVRIECKCGTESCRKYLF

hide sequence

Ensembl Acc Id:

ENSSTOP00000013735 ⟸ ENSSTOT00000015329

Protein Domains

Chromo Post-SET Pre-SET SET

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000015328	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000015329.3	UniProtKB/TrEMBL
Gene3D-CATH	2.170.270.10	UniProtKB/TrEMBL
	2.40.50.40	UniProtKB/TrEMBL
InterPro	Chromo-like_dom_sf	UniProtKB/TrEMBL
	Chromo/chromo_shadow_dom	UniProtKB/TrEMBL
	Chromo_domain	UniProtKB/TrEMBL
	Chromodomain_CS	UniProtKB/TrEMBL
	H3K9_Histone-Lys_N-MTase	UniProtKB/TrEMBL
	Histone_H3-K9_MeTrfase	UniProtKB/TrEMBL
	Post-SET_dom	UniProtKB/TrEMBL
	Pre-SET_dom	UniProtKB/TrEMBL
	SET_dom	UniProtKB/TrEMBL
	SET_dom_sf	UniProtKB/TrEMBL
NCBI Gene	Suv39h1	ENTREZGENE
PANTHER	HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H	UniProtKB/TrEMBL
	HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H1	UniProtKB/TrEMBL
Pfam	Chromo	UniProtKB/TrEMBL
	Pre-SET	UniProtKB/TrEMBL
	SET	UniProtKB/TrEMBL
PIRSF	SUV39_SET	UniProtKB/TrEMBL
PROSITE	CHROMO_1	UniProtKB/TrEMBL
	CHROMO_2	UniProtKB/TrEMBL
	POST_SET	UniProtKB/TrEMBL
	PRE_SET	UniProtKB/TrEMBL
	SAM_MT43_SUVAR39_3	UniProtKB/TrEMBL
	SET	UniProtKB/TrEMBL
SMART	CHROMO	UniProtKB/TrEMBL
	PostSET	UniProtKB/TrEMBL
	PreSET	UniProtKB/TrEMBL
	SET	UniProtKB/TrEMBL
Superfamily-SCOP	SSF54160	UniProtKB/TrEMBL
	SSF82199	UniProtKB/TrEMBL
UniProt	I3MPK2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-08-17	Suv39h1	SUV39H1 histone lysine methyltransferase	Suv39h1	suppressor of variegation 3-9 homolog 1	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations