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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of osteoblast differentiation
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Accession:GO:0045669 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of osteoblast differentiation.
Synonyms:exact_synonym: up regulation of osteoblast differentiation;   upregulation of osteoblast differentiation
 narrow_synonym: activation of osteoblast differentiation;   stimulation of osteoblast differentiation

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positive regulation of osteoblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004955449:15,587,958...15,706,432
Ensembl chrNW_004955449:15,640,230...15,708,694 		JBrowse link
G Acvr2a activin A receptor type 2A involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004955440:13,849,926...13,931,374
Ensembl chrNW_004955440:13,849,926...13,931,374 		JBrowse link
G Acvr2b activin A receptor type 2B involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004955427:25,438,652...25,467,360
Ensembl chrNW_004955427:25,438,652...25,467,360 		JBrowse link
G Atraid all-trans retinoic acid induced differentiation factor involved_in ISO (PMID:21723284) UniProt PMID:21723284 NCBI chrNW_004955469:9,194,656...9,203,292 JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within		 ISO (MGI:5009350|PMID:20675382)
(PMID:15175325), (PMID:16099986)		 BHF-UCL
MGI		 PMID:15175325 PMID:16099986 PMID:20675382 MGI:5009350 NCBI chrNW_004955415:17,048,374...17,058,172
Ensembl chrNW_004955415:17,048,030...17,060,181 		JBrowse link
G Bmp4 bone morphogenetic protein 4 acts_upstream_of_or_within
involved_in		 ISO (PMID:14749725)
(PMID:18436533)		 RGD
MGI
BHF-UCL		 PMID:14749725 PMID:16245174 PMID:17112416 PMID:18436533 RGD:1643600 RGD:2289011 NCBI chrNW_004955409:9,432,835...9,439,680
Ensembl chrNW_004955409:9,432,841...9,440,303 		JBrowse link
G Bmp6 bone morphogenetic protein 6 involved_in ISO (PMID:18436533) RGD
BHF-UCL		 PMID:9202223 PMID:18436533 RGD:2289027 NCBI chrNW_004955465:6,053,600...6,201,254
Ensembl chrNW_004955465:6,054,931...6,200,377 		JBrowse link
G Bmp7 bone morphogenetic protein 7 involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004955445:2,154,057...2,235,594
Ensembl chrNW_004955445:2,153,170...2,235,795 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004955510:5,812,571...5,936,312
Ensembl chrNW_004955510:5,905,008...5,936,312 		JBrowse link
G Bmpr1b bone morphogenetic protein receptor type 1B involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004955405:5,408,171...5,784,930
Ensembl chrNW_004955405:5,700,162...5,787,957 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004955457:12,235,780...12,315,680
Ensembl chrNW_004955457:12,235,780...12,316,727 		JBrowse link
G Ccn1 cellular communication network factor 1 involved_in ISO (PMID:20675382) BHF-UCL PMID:20675382 NCBI chrNW_004955423:8,416,498...8,419,029
Ensembl chrNW_004955423:8,413,725...8,419,166 		JBrowse link
G Ccn4 cellular communication network factor 4 involved_in ISO (PMID:20684029) UniProt PMID:20684029 NCBI chrNW_004955461:7,748,399...7,780,359
Ensembl chrNW_004955461:7,748,005...7,780,427 		JBrowse link
G Cd276 CD276 molecule acts_upstream_of_or_within ISO (PMID:15317945) MGI PMID:15317945 NCBI chrNW_004955450:3,884,437...3,896,416 JBrowse link
G Cebpa CCAAT enhancer binding protein alpha acts_upstream_of_or_within ISO (PMID:15175325) MGI PMID:15175325 NCBI chrNW_004955468:3,046,544...3,049,217
Ensembl chrNW_004955468:3,047,931...3,049,080 		JBrowse link
G Cebpb CCAAT enhancer binding protein beta acts_upstream_of_or_within ISO (PMID:15175325) MGI PMID:15175325 NCBI chrNW_004955445:8,060,432...8,061,289 JBrowse link
G Cebpd CCAAT enhancer binding protein delta acts_upstream_of_or_within ISO (PMID:15175325) MGI PMID:15175325 NCBI chrNW_004955454:7,711,010...7,711,680 JBrowse link
G Clic1 chloride intracellular channel 1 acts_upstream_of_or_within ISO (PMID:19703605) MGI PMID:19703605 NCBI chrNW_004955437:269,276...275,949
Ensembl chrNW_004955437:269,276...275,949 		JBrowse link
G Cthrc1 collagen triple helix repeat containing 1 acts_upstream_of_or_within ISO (PMID:18779865) MGI PMID:18779865 NCBI chrNW_004955417:27,520,420...27,525,907 JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within ISO (PMID:15866163) MGI PMID:15866163 NCBI chrNW_004955420:29,030,716...29,047,447
Ensembl chrNW_004955420:29,030,716...29,047,449 		JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 involved_in ISO (PMID:20564243) UniProt PMID:20564243 NCBI chrNW_004955462:13,578,638...13,644,834
Ensembl chrNW_004955462:13,584,724...13,642,968 		JBrowse link
G Dlx5 distal-less homeobox 5 ISO RGD PMID:12815054 RGD:1298882 NCBI chrNW_004955432:13,429,832...13,434,160
Ensembl chrNW_004955432:13,429,415...13,434,258 		JBrowse link
G Dnai3 dynein axonemal intermediate chain 3 involved_in ISO (MGI:6450489|PMID:25498833) UniProt PMID:25498833 MGI:6450489 NCBI chrNW_004955423:8,870,877...8,928,070
Ensembl chrNW_004955423:8,870,602...8,928,743 		JBrowse link
G Fam20c FAM20C golgi associated secretory pathway kinase acts_upstream_of_or_within ISO (PMID:22615579) MGI PMID:22615579 NCBI chrNW_004955460:8,142,325...8,192,044
Ensembl chrNW_004955460:8,143,824...8,193,825 		JBrowse link
G Fbn2 fibrillin 2 involved_in ISO (MGI:4836762|PMID:20855508) BHF-UCL PMID:20855508 MGI:4836762 NCBI chrNW_004955415:1,307,553...1,535,435
Ensembl chrNW_004955415:1,309,077...1,537,052 		JBrowse link
G Fbxo5 F-box protein 5 involved_in ISO (PMID:29850565) UniProt PMID:29850565 NCBI chrNW_004955439:8,830,658...8,843,653
Ensembl chrNW_004955439:8,830,975...8,843,828 		JBrowse link
G Fermt2 FERM domain containing kindlin 2 involved_in ISO (PMID:29496737)
(MGI:6149626|PMID:29496737)		 ARUK-UCL PMID:29496737 MGI:6149626 NCBI chrNW_004955409:10,285,780...10,327,286
Ensembl chrNW_004955409:10,285,793...10,327,468 		JBrowse link
G Ffar4 free fatty acid receptor 4 involved_in ISO (MGI:6220333|PMID:26365922) UniProt PMID:26365922 MGI:6220333 NCBI chrNW_004955507:81,910...110,047
Ensembl chrNW_004955507:81,284...110,047 		JBrowse link
G Fgf2 fibroblast growth factor 2 acts_upstream_of_or_within ISO (PMID:20570969) MGI PMID:20570969 NCBI chrNW_004955428:17,840,554...17,894,779
Ensembl chrNW_004955428:17,840,628...17,894,773 		JBrowse link
G Gdf10 growth differentiation factor 10 ISO RGD PMID:12559390 RGD:2316372 NCBI chrNW_004955556:2,185,121...2,195,150
Ensembl chrNW_004955556:2,185,121...2,196,502 		JBrowse link
G Gdpd2 glycerophosphodiester phosphodiesterase domain containing 2 acts_upstream_of_or_within ISO (PMID:12933806) MGI PMID:12933806 NCBI chrNW_004955475:9,972,797...9,983,145
Ensembl chrNW_004955475:9,972,664...9,985,939 		JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO (PMID:20570969) MGI PMID:20570969 NCBI chrNW_004955460:1,528,457...1,805,584
Ensembl chrNW_004955460:1,528,412...1,805,918 		JBrowse link
G Hey1 hes related family bHLH transcription factor with YRPW motif 1 acts_upstream_of_or_within ISO (PMID:18986983) MGI PMID:18986983 NCBI chrNW_004955444:1,498,444...1,502,099
Ensembl chrNW_004955444:1,498,675...1,500,945 		JBrowse link
G Ifi16 interferon gamma inducible protein 16 acts_upstream_of_or_within ISO (PMID:15557274) MGI PMID:15557274 NCBI chrNW_004955468:10,828,726...10,845,853 JBrowse link
G Igf1 insulin like growth factor 1 involved_in ISO (PMID:16433617) RGD
BHF-UCL		 PMID:16433617 PMID:16897348 RGD:1598452 NCBI chrNW_004955405:37,505,830...37,582,152
Ensembl chrNW_004955405:37,512,201...37,582,152 		JBrowse link
G Il6 interleukin 6 involved_in ISO (PMID:30545407) ARUK-UCL PMID:30545407 NCBI chrNW_004955410:25,079,835...25,084,390 JBrowse link
G Il6st interleukin 6 cytokine family signal transducer involved_in ISO (PMID:12372336) BHF-UCL PMID:12372336 NCBI chrNW_004955446:11,790,636...11,837,734
Ensembl chrNW_004955446:11,790,444...11,835,001 		JBrowse link
G Ilk integrin linked kinase involved_in ISO (MGI:5009350|PMID:20675382) BHF-UCL PMID:20675382 MGI:5009350 NCBI chrNW_004955414:22,316,243...22,322,979
Ensembl chrNW_004955414:22,316,047...22,322,979 		JBrowse link
G Jag1 jagged canonical Notch ligand 1 acts_upstream_of_or_within ISO (PMID:23980096) MGI PMID:23980096 NCBI chrNW_004955415:20,490,414...20,526,068
Ensembl chrNW_004955415:20,490,414...20,527,917 		JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit acts_upstream_of_or_within ISO (PMID:15563473) MGI PMID:15563473 NCBI chrNW_004955524:3,176,849...3,177,936 JBrowse link
G Lmna lamin A/C ISO RGD PMID:22119912 RGD:10003161 NCBI chrNW_004955545:2,290,076...2,310,982
Ensembl chrNW_004955545:2,290,037...2,313,033 		JBrowse link
G Lrp3 LDL receptor related protein 3 involved_in ISO (PMID:28340487) ARUK-UCL PMID:28340487 NCBI chrNW_004955468:2,957,156...2,967,678
Ensembl chrNW_004955468:2,957,145...2,967,678 		JBrowse link
G Lrp5 LDL receptor related protein 5 involved_in ISO (MGI:6162346|PMID:26891291) BHF-UCL PMID:26891291 MGI:6162346 NCBI chrNW_004955422:17,394,371...17,475,244
Ensembl chrNW_004955422:17,394,371...17,505,763 		JBrowse link
G Ltf lactotransferrin involved_in ISO (PMID:15166119) UniProt PMID:15166119 NCBI chrNW_004955420:25,580,449...25,604,277
Ensembl chrNW_004955420:25,580,359...25,604,331 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISO (MGI:5285459|PMID:21652706) UniProt PMID:21652706 MGI:5285459 NCBI chrNW_004955418:22,537,388...22,701,434
Ensembl chrNW_004955418:22,537,285...22,701,434 		JBrowse link
G Men1 menin 1 acts_upstream_of_or_within ISO (PMID:15150273) MGI PMID:15150273 NCBI chrNW_004955422:20,356,491...20,363,374
Ensembl chrNW_004955422:20,356,491...20,363,575 		JBrowse link
G Msx2 msh homeobox 2 acts_upstream_of_or_within ISO (PMID:15175325) MGI PMID:15175325 NCBI chrNW_004955408:27,323,405...27,329,484
Ensembl chrNW_004955408:27,323,360...27,329,755 		JBrowse link
G Nell1 neural EGFL like 1 involved_in ISO (PMID:21723284) UniProt PMID:21723284 NCBI chrNW_004955476:1,445,234...2,236,954
Ensembl chrNW_004955476:1,445,353...2,233,146 		JBrowse link
G Npnt nephronectin involved_in ISO (MGI:4414689|PMID:19944102), (MGI:5285024|PMID:21689636) BHF-UCL PMID:19944102 PMID:21689636 MGI:4414689 MGI:5285024 NCBI chrNW_004955496:3,321,310...3,388,625
Ensembl chrNW_004955496:3,320,946...3,388,694 		JBrowse link
G Nppc natriuretic peptide C ISO RGD PMID:17562543 RGD:1642298 NCBI chrNW_004955453:3,884,580...3,888,494
Ensembl chrNW_004955453:3,884,560...3,888,850 		JBrowse link
G Pdlim7 PDZ and LIM domain 7 ISO RGD PMID:9832452 RGD:632731 NCBI chrNW_004955408:29,718,830...29,734,085
Ensembl chrNW_004955408:29,718,644...29,734,085 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha involved_in ISO (MGI:3610779|PMID:16286645) UniProt PMID:16286645 MGI:3610779 NCBI chrNW_004955496:6,934,542...7,059,745
Ensembl chrNW_004955496:6,908,224...7,059,816 		JBrowse link
G Prkd1 protein kinase D1 involved_in ISO (MGI:5306577|PMID:19029091) UniProt PMID:19029091 MGI:5306577 NCBI chrNW_004955409:30,554,095...30,860,588
Ensembl chrNW_004955409:30,554,013...30,860,649 		JBrowse link
G Ptger4 prostaglandin E receptor 4 ISO RGD PMID:14751573 RGD:10043372 NCBI chrNW_004955426:24,997,811...25,010,822
Ensembl chrNW_004955426:24,997,811...25,010,822 		JBrowse link
G Runx2 RUNX family transcription factor 2 involved_in
acts_upstream_of_or_within		 ISO (PMID:28703881)
(PMID:15150273)
(PMID:15175325)
(PMID:18986983)		 UniProt
MGI		 PMID:15150273 PMID:15175325 PMID:18986983 PMID:28703881 NCBI chrNW_004955437:10,598,145...10,885,858
Ensembl chrNW_004955437:10,598,145...10,800,560 		JBrowse link
G Scube2 signal peptide, CUB domain and EGF like domain containing 2 acts_upstream_of_or_within ISO (PMID:25639508) MGI PMID:25639508 NCBI chrNW_004955414:24,751,134...24,818,338
Ensembl chrNW_004955414:24,752,629...24,818,336 		JBrowse link
G Scube3 signal peptide, CUB domain and EGF like domain containing 3 involved_in ISO (PMID:33308444)
(MGI:6716484|PMID:33308444)		 UniProt PMID:33308444 MGI:6716484 NCBI chrNW_004955437:3,178,985...3,213,772
Ensembl chrNW_004955437:3,178,985...3,213,772 		JBrowse link
G Sfrp2 secreted frizzled related protein 2 acts_upstream_of_or_within ISO (PMID:18166153) MGI PMID:18166153 NCBI chrNW_004955471:8,103,937...8,112,596
Ensembl chrNW_004955471:8,103,783...8,112,321 		JBrowse link
G Smad1 SMAD family member 1 acts_upstream_of_or_within ISO (PMID:15150273) MGI PMID:15150273 NCBI chrNW_004955428:1,357,398...1,429,521
Ensembl chrNW_004955428:1,361,085...1,429,948 		JBrowse link
G Smad5 SMAD family member 5 involved_in
acts_upstream_of_or_within		 ISO (PMID:32271402)
(PMID:15150273)		 BHF-UCL
MGI		 PMID:15150273 PMID:32271402 NCBI chrNW_004955408:31,183,727...31,228,355
Ensembl chrNW_004955408:31,183,659...31,229,384 		JBrowse link
G Sox11 SRY-box transcription factor 11 involved_in ISO (PMID:20626275) UniProt PMID:20626275 NCBI chrNW_004955487:2,678,961...2,680,869
Ensembl chrNW_004955487:2,679,145...2,680,521 		JBrowse link
G Suco SUN domain containing ossification factor involved_in ISO (MGI:4452525|PMID:20440000) UniProt PMID:20440000 MGI:4452525 NCBI chrNW_004955406:12,985,339...13,064,863
Ensembl chrNW_004955406:12,985,856...13,065,855 		JBrowse link
G Tent5a terminal nucleotidyltransferase 5A involved_in ISO (MGI:6717031|PMID:33882302) UniProt PMID:33882302 MGI:6717031 NCBI chrNW_004955411:9,695,149...9,701,463
Ensembl chrNW_004955411:9,699,011...9,701,507 		JBrowse link
G Tmem119 transmembrane protein 119 involved_in ISO (PMID:20025746)
(MGI:6294241|PMID:22579779)
(MGI:4418582|PMID:20025746), (MGI:5543589|PMID:22416756)		 UniProt
ARUK-UCL		 PMID:20025746 PMID:22416756 PMID:22579779 MGI:4418582 MGI:5543589 MGI:6294241 NCBI chrNW_004955455:9,856,443...9,863,100
Ensembl chrNW_004955455:9,856,443...9,863,100 		JBrowse link
G Tp63 tumor protein p63 involved_in ISO (PMID:22521434) BHF-UCL PMID:22521434 NCBI chrNW_004955420:18,178,639...18,384,786
Ensembl chrNW_004955420:18,176,155...18,384,786 		JBrowse link
G Vegfa vascular endothelial growth factor A acts_upstream_of_or_within ISO (PMID:22886301) MGI PMID:22886301 NCBI chrNW_004955437:9,527,445...9,541,908 JBrowse link
G Wnt10b Wnt family member 10B acts_upstream_of_or_within ISO (PMID:15728361), (PMID:19723499) MGI PMID:15728361 PMID:19723499 NCBI chrNW_004955500:7,782,782...7,800,281
Ensembl chrNW_004955500:7,782,782...7,788,309 		JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO (PMID:17720811) BHF-UCL PMID:17720811 NCBI chrNW_004955452:2,319,446...2,344,740
Ensembl chrNW_004955452:2,319,446...2,344,989 		JBrowse link
G Wnt7b Wnt family member 7B acts_upstream_of_or_within ISO (PMID:15576404) MGI PMID:15576404 NCBI chrNW_004955413:30,146,185...30,185,693
Ensembl chrNW_004955413:30,144,869...30,181,791 		JBrowse link
G Wwtr1 WW domain containing transcription regulator 1 involved_in ISO (PMID:29496737) ARUK-UCL PMID:29496737 NCBI chrNW_004955448:745,419...868,313
Ensembl chrNW_004955448:745,419...868,602 		JBrowse link
G Yap1 Yes1 associated transcriptional regulator involved_in ISO (PMID:29496737) ARUK-UCL PMID:29496737 NCBI chrNW_004955412:5,423,866...5,533,728
Ensembl chrNW_004955412:5,423,855...5,534,408 		JBrowse link
G Zhx3 zinc fingers and homeoboxes 3 involved_in ISO (PMID:21174497) UniProt PMID:21174497 NCBI chrNW_004955445:15,632,723...15,785,238
Ensembl chrNW_004955445:15,632,995...15,785,238 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12352
    positive regulation of biological process 5600
      positive regulation of cellular process 5149
        positive regulation of cell differentiation 903
          positive regulation of osteoblast differentiation 72
Path 2
Term Annotations click to browse term
  biological_process 12352
    developmental process 5861
      cellular developmental process 3879
        cell differentiation 3878
          regulation of cell differentiation 1528
            regulation of osteoblast differentiation 140
              positive regulation of osteoblast differentiation 72
paths to the root