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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of macrophage cytokine production
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Accession:GO:0010935 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.

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regulation of macrophage cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Litaf lipopolysaccharide induced TNF factor acts_upstream_of_or_within ISO (PMID:16954198) MGI PMID:16954198 NCBI chrNW_004955442:7,054,418...7,084,973
Ensembl chrNW_004955442:7,077,823...7,083,437 		JBrowse link
G Ube2j1 ubiquitin conjugating enzyme E2 J1 acts_upstream_of_or_within ISO (PMID:24020373) MGI PMID:24020373 NCBI chrNW_004955411:16,076,647...16,091,554
Ensembl chrNW_004955411:16,074,551...16,091,570 		JBrowse link
negative regulation of macrophage cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp5 acid phosphatase 5, tartrate resistant acts_upstream_of_or_within ISO (PMID:11168643) MGI PMID:11168643 NCBI chrNW_004955495:2,418,113...2,421,181
Ensembl chrNW_004955495:2,418,364...2,421,538 		JBrowse link
G Atg9a autophagy related 9A acts_upstream_of_or_within ISO (PMID:24670807) MGI PMID:24670807 NCBI chrNW_004955453:14,203,798...14,214,760
Ensembl chrNW_004955453:14,206,065...14,213,729 		JBrowse link
G Axl AXL receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:16831897) MGI PMID:16831897 NCBI chrNW_004955555:189,445...218,509
Ensembl chrNW_004955555:189,174...218,565 		JBrowse link
G Cuedc2 CUE domain containing 2 acts_upstream_of_or_within ISO (PMID:24882011) MGI PMID:24882011 NCBI chrNW_004955485:7,969,389...7,977,073
Ensembl chrNW_004955485:7,975,190...7,976,875 		JBrowse link
G Epx eosinophil peroxidase acts_upstream_of_or_within ISO (PMID:16926417) MGI PMID:16926417 NCBI chrNW_004955451:4,818,809...4,828,913
Ensembl chrNW_004955451:4,818,809...4,828,913 		JBrowse link
G Irak3 interleukin 1 receptor associated kinase 3 involved_in ISO (MGI:2183694|PMID:12150927) BHF-UCL PMID:12150927 MGI:2183694 NCBI chrNW_004955458:12,839,995...12,880,285
Ensembl chrNW_004955458:12,846,237...12,879,316 		JBrowse link
G Nlrx1 NLR family member X1 acts_upstream_of_or_within ISO (PMID:21703540) MGI PMID:21703540 NCBI chrNW_004955412:20,275,767...20,287,414
Ensembl chrNW_004955412:20,275,917...20,287,414 		JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:15220916) MGI PMID:15220916 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710 		JBrowse link
G Tgfb1 transforming growth factor beta 1 involved_in ISO (PMID:20875417) DFLAT PMID:20875417 NCBI chrNW_004955555:274,405...288,441
Ensembl chrNW_004955555:270,652...288,441 		JBrowse link
G Tgfb2 transforming growth factor beta 2 involved_in ISO (PMID:20875417) DFLAT PMID:20875417 NCBI chrNW_004955406:174,949...249,248
Ensembl chrNW_004955406:172,814...249,248 		JBrowse link
G Tgfb3 transforming growth factor beta 3 involved_in ISO (PMID:20875417) DFLAT PMID:20875417 NCBI chrNW_004955438:33,129...55,180
Ensembl chrNW_004955438:29,415...55,180 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 acts_upstream_of_or_within ISO (PMID:16831897) MGI PMID:16831897 NCBI chrNW_004955410:22,003,981...22,005,483 JBrowse link
G Twist2 twist family bHLH transcription factor 2 acts_upstream_of_or_within ISO (PMID:16831897) MGI PMID:16831897 NCBI chrNW_004955542:1,959,765...2,000,665
Ensembl chrNW_004955542:1,959,765...2,000,665 		JBrowse link
positive regulation of macrophage cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Card9 caspase recruitment domain family member 9 acts_upstream_of_or_within ISO (PMID:17187069) MGI PMID:17187069 NCBI chrNW_004955513:4,350,873...4,359,345
Ensembl chrNW_004955513:4,350,147...4,359,345 		JBrowse link
G Cd36 CD36 molecule (CD36 blood group) acts_upstream_of_or_within ISO (PMID:16061696)
(PMID:15690042)		 MGI PMID:15690042 PMID:16061696 NCBI chrNW_004955410:5,003,720...5,120,903
Ensembl chrNW_004955410:5,003,668...5,075,313 		JBrowse link
G Cd74 CD74 molecule involved_in ISO (MGI:4943655|PMID:19413900) BHF-UCL PMID:19413900 MGI:4943655 NCBI chrNW_004955415:4,129,151...4,138,336
Ensembl chrNW_004955415:4,129,254...4,137,826 		JBrowse link
G Gprc5b G protein-coupled receptor class C group 5 member B involved_in ISO (MGI:5545939|PMID:23169819) UniProt PMID:23169819 MGI:5545939 NCBI chrNW_004955442:3,548,478...3,571,341
Ensembl chrNW_004955442:3,548,478...3,571,341 		JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:9348310) MGI PMID:9348310 NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (MGI:6391873|PMID:22733818) ARUK-UCL PMID:22733818 MGI:6391873 NCBI chrNW_004955452:9,335,481...9,358,177
Ensembl chrNW_004955452:9,334,587...9,358,444 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 acts_upstream_of_or_within ISO (PMID:24020373) MGI PMID:24020373 NCBI chrNW_004955406:42,231,858...42,276,477
Ensembl chrNW_004955406:42,231,858...42,276,477 		JBrowse link
G Myd88 MYD88 innate immune signal transduction adaptor acts_upstream_of_or_within ISO (PMID:10607756), (PMID:11067888), (PMID:12872135)
(PMID:12872135)		 MGI PMID:10607756 PMID:11067888 PMID:12872135 NCBI chrNW_004955427:25,553,589...25,557,654
Ensembl chrNW_004955427:25,553,589...25,559,138 		JBrowse link
G Nod1 nucleotide binding oligomerization domain containing 1 acts_upstream_of_or_within ISO (PMID:18261938) MGI PMID:18261938 NCBI chrNW_004955410:31,681,191...31,725,173
Ensembl chrNW_004955410:31,681,077...31,725,173 		JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:14560001), (PMID:15220916)
(PMID:15220916), (PMID:18261938)
(PMID:15692051), (PMID:18261938)
(PMID:18261938)		 MGI PMID:14560001 PMID:15220916 PMID:15692051 PMID:18261938 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (PMID:18490713)
(PMID:11016935)		 MGI PMID:11016935 PMID:18490713 NCBI chrNW_004955482:7,048,674...7,087,525
Ensembl chrNW_004955482:7,048,776...7,086,926 		JBrowse link
G Panx1 pannexin 1 acts_upstream_of_or_within ISO (PMID:18490713) MGI PMID:18490713 NCBI chrNW_004955414:405,483...448,470
Ensembl chrNW_004955414:401,188...448,470 		JBrowse link
G Plcg2 phospholipase C gamma 2 acts_upstream_of ISO (MGI:5300086|PMID:22041900) ARUK-UCL PMID:22041900 MGI:5300086 NCBI chrNW_004955522:4,352,890...4,480,735
Ensembl chrNW_004955522:4,358,233...4,468,986 		JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within ISO (PMID:11894098), (PMID:18261938) MGI PMID:11894098 PMID:18261938 NCBI chrNW_004955417:6,669,675...6,698,142
Ensembl chrNW_004955417:6,669,675...6,702,228 		JBrowse link
G Rtn4 reticulon 4 involved_in ISO (MGI:4366092|PMID:19805174) UniProt PMID:19805174 MGI:4366092 NCBI chrNW_004955424:28,061,346...28,125,838 JBrowse link
G Sema7a semaphorin 7A (JohnMiltonHagen blood group) involved_in ISO (MGI:3710037|PMID:17377534) UniProt PMID:17377534 MGI:3710037 NCBI chrNW_004955450:3,401,732...3,424,547
Ensembl chrNW_004955450:3,401,777...3,423,363 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (MGI:5319292|PMID:22315447) UniProt PMID:22315447 MGI:5319292 NCBI chrNW_004955425:20,280,725...20,307,663
Ensembl chrNW_004955425:20,279,963...20,307,663 		JBrowse link
G Spon2 spondin 2 acts_upstream_of_or_within ISO (PMID:14691481) MGI PMID:14691481 NCBI chrNW_004955514:598,840...603,390
Ensembl chrNW_004955514:596,829...604,051 		JBrowse link
G Ticam1 toll like receptor adaptor molecule 1 acts_upstream_of_or_within ISO (PMID:12855817)
(PMID:12872135)		 MGI PMID:12855817 PMID:12872135 NCBI chrNW_004955495:4,197,083...4,204,999
Ensembl chrNW_004955495:4,202,372...4,204,513 		JBrowse link
G Tirap TIR domain containing adaptor protein acts_upstream_of_or_within ISO (PMID:15690042) MGI PMID:15690042 NCBI chrNW_004955412:27,303,548...27,315,031
Ensembl chrNW_004955412:27,312,489...27,315,031 		JBrowse link
G Tlr2 toll like receptor 2 acts_upstream_of_or_within ISO (PMID:18261938)
(PMID:15690042)
(PMID:10549626), (PMID:11067888)		 MGI PMID:10549626 PMID:11067888 PMID:15690042 PMID:18261938 NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258 		JBrowse link
G Tlr3 toll like receptor 3 acts_upstream_of_or_within ISO (PMID:18261938)
(PMID:12855817)		 MGI PMID:12855817 PMID:18261938 NCBI chrNW_004955403:22,977,882...23,001,392
Ensembl chrNW_004955403:22,979,120...23,001,467 		JBrowse link
G Tlr4 toll like receptor 4 acts_upstream_of_or_within ISO (PMID:10623794)
(PMID:10549626), (PMID:10607756), (PMID:15661922)
(PMID:18261938), (PMID:21609717)
(PMID:14691481)		 MGI PMID:10549626 PMID:10607756 PMID:10623794 PMID:14691481 PMID:15661922 More... NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135 		JBrowse link
G Tlr7 toll like receptor 7 acts_upstream_of_or_within ISO (PMID:18261938) MGI PMID:18261938 NCBI chrNW_004955544:424,897...443,562
Ensembl chrNW_004955544:424,850...443,564 		JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO (PMID:18174455) UniProt PMID:18174455 NCBI chrNW_004955430:5,304,817...5,325,684
Ensembl chrNW_004955430:5,304,745...5,325,684 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12352
    multicellular organismal process 6191
      cytokine production 702
        regulation of cytokine production 695
          regulation of cytokine production involved in immune response 114
            regulation of macrophage cytokine production 39
              negative regulation of macrophage cytokine production 13
              positive regulation of macrophage cytokine production 25
Path 2
Term Annotations click to browse term
  biological_process 12352
    biological regulation 8890
      regulation of biological process 8624
        regulation of metabolic process 4805
          regulation of biosynthetic process 3814
            regulation of cellular biosynthetic process 3730
              regulation of macromolecule biosynthetic process 3637
                regulation of gene expression 3526
                  regulation of cytokine production 695
                    regulation of cytokine production involved in immune response 114
                      regulation of macrophage cytokine production 39
                        negative regulation of macrophage cytokine production 13
                        positive regulation of macrophage cytokine production 25
paths to the root