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ONTOLOGY REPORT - ANNOTATIONS


Term:glycosphingolipid biosynthetic process
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Accession:GO:0006688 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.
Synonyms:exact_synonym: glycosphingolipid anabolism;   glycosphingolipid biosynthesis;   glycosphingolipid formation;   glycosphingolipid synthesis



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glycosphingolipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A3galt2 alpha 1,3-galactosyltransferase 2 acts_upstream_of_or_within
involved_in
IDA
ISO
MGI:1347344|MGI:3512453 (PMID:22875802)
PMID:10854427
PMID:12626403
RGD PMID:22875802 PMID:10854427 PMID:10854427 PMID:12626403 RGD:1299594, RGD:1299594, RGD:632674 NCBI chr 5:141,101,329...141,113,760
Ensembl chr 5:141,107,983...141,115,641
JBrowse link
G B4galnt1 beta-1,4-N-acetyl-galactosaminyl transferase 1 involved_in IDA PMID:1606358 UniProt PMID:1606358 RGD:21201272 NCBI chr 7:62,988,429...62,996,190
Ensembl chr 7:62,988,930...62,996,190
JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 involved_in IDA
IBA
GO_REF:0000033 GO_Central
RGD
PMID:9593693 GO_REF:0000033, RGD:70807 NCBI chr18:11,958,382...12,015,247
Ensembl chr18:11,958,390...12,015,247
JBrowse link
G Fut4 fucosyltransferase 4 involved_in ISO
ISS
(PMID:29593094)
GO_REF:0000024
RGD
UniProt
PMID:29593094 GO_REF:0000024 NCBI chr 8:11,586,721...11,590,682
Ensembl chr 8:11,586,721...11,590,682
JBrowse link
G Fut4-ps1 fucosyltransferase 4, pseudogene 1 involved_in ISO (PMID:29593094) RGD PMID:29593094 NCBI chr 9:1,569,605...1,572,022 JBrowse link
G Fut9 fucosyltransferase 9 involved_in ISO
ISS
(PMID:29593094)
GO_REF:0000024
RGD
UniProt
PMID:29593094 GO_REF:0000024 NCBI chr 5:39,351,815...39,565,256
Ensembl chr 5:39,351,819...39,565,130
JBrowse link
G St6galnac5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 involved_in ISO (MGI:1346847|PMID:10521438) RGD PMID:10521438 MGI:1346847 NCBI chr 2:241,741,933...241,911,214
Ensembl chr 2:241,742,688...241,911,208
JBrowse link
G St8sia5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 involved_in IDA PMID:1606358 UniProt PMID:1606358 RGD:21201272 NCBI chr18:70,736,395...70,802,537
Ensembl chr18:70,736,602...70,797,789
JBrowse link
G Tm9sf2 transmembrane 9 superfamily member 2 involved_in ISO (PMID:30660999) RGD PMID:30660999 NCBI chr15:99,201,556...99,254,054
Ensembl chr15:99,201,489...99,254,049
JBrowse link
G Ugt8 UDP glycosyltransferase 8 TAS RGD PMID:7521399 RGD:70050 NCBI chr 2:214,264,483...214,332,769
Ensembl chr 2:214,264,483...214,332,660
JBrowse link
galactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3galt1 Beta-1,3-galactosyltransferase 1 involved_in ISO (PMID:9582303) RGD PMID:9582303 NCBI chr 3:52,253,413...52,826,508
Ensembl chr 3:52,253,618...52,825,313
JBrowse link
G B3galt2 Beta-1,3-galactosyltransferase 2 involved_in ISO (PMID:9582303) RGD PMID:9582303 NCBI chr13:55,389,406...55,398,419
Ensembl chr13:55,389,406...55,398,419
JBrowse link
G B4galt3 beta-1,4-galactosyltransferase 3 involved_in ISO
IBA
IEA
(PMID:9405390)
GO_REF:0000033
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:9405390 GO_REF:0000033 GO_REF:0000107 NCBI chr13:83,691,378...83,697,448
Ensembl chr13:83,691,446...83,697,448
JBrowse link
G Fa2h fatty acid 2-hydroxylase involved_in ISS
ISO
IMP
IEA
GO_REF:0000024
(MGI:3696647|PMID:15658937), (MGI:3826747|PMID:18815260)
PMID:17901466
GO_REF:0000041
UniProt
RGD
PMID:15658937 PMID:18815260 PMID:17901466 GO_REF:0000024 GO_REF:0000041 MGI:3696647 MGI:3826747, RGD:13825191 NCBI chr19:39,312,904...39,364,153
Ensembl chr19:39,312,906...39,364,153
JBrowse link
G Gal3st1 galactose-3-O-sulfotransferase 1 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:10727929)
GO_Central
RGD
PMID:10727929 GO_REF:0000033 NCBI chr14:78,868,049...78,886,402
Ensembl chr14:78,870,793...78,886,388
JBrowse link
G Ugt8 UDP glycosyltransferase 8 involved_in IDA
IBA
IEA
PMID:8713090
GO_REF:0000033
GO_REF:0000041
GO_Central
UniProt
PMID:8713090 GO_REF:0000033 GO_REF:0000041, RGD:39458006 NCBI chr 2:214,264,483...214,332,769
Ensembl chr 2:214,264,483...214,332,660
JBrowse link
ganglioside biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3galt4 Beta-1,3-galactosyltransferase 4 involved_in ISO
IEA
(PMID:9582303)
GO_REF:0000107
RGD
Ensembl
PMID:9582303 GO_REF:0000107 NCBI chr20:4,936,089...4,937,664
Ensembl chr20:4,931,768...4,938,315
JBrowse link
G B4galnt1 beta-1,4-N-acetyl-galactosaminyl transferase 1 involved_in
acts_upstream_of_or_within
ISS
ISO
IBA
IEA
IDA
GO_REF:0000024
MGI:2158349|MGI:96074 (PMID:10021458)
GO_REF:0000033
GO_REF:0000118
GO_REF:0000107
(MGI:83232|PMID:8855236)
PMID:3140234
(PMID:1601877), (PMID:7487055), (PMID:7890749)
UniProt
RGD
GO_Central
TreeGrafter
Ensembl
PMID:1601877 PMID:7487055 PMID:7890749 PMID:8855236 PMID:10021458 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 MGI:83232, RGD:21201261 NCBI chr 7:62,988,429...62,996,190
Ensembl chr 7:62,988,930...62,996,190
JBrowse link
G Rps18 ribosomal protein S18 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:4,931,427...4,935,538
Ensembl chr10:101,204,500...101,205,146
Ensembl chr20:101,204,500...101,205,146
JBrowse link
G St6galnac3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 involved_in IBA
IEA
GO_REF:0000033
GO_REF:0000118
GO_Central
TreeGrafter
GO_REF:0000033 GO_REF:0000118 NCBI chr 2:242,129,755...242,645,120
Ensembl chr 2:242,129,763...242,645,133
JBrowse link
G St6galnac4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:15,872,230...15,885,250
Ensembl chr 3:15,872,532...15,885,243
JBrowse link
G St6galnac5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:241,741,933...241,911,214
Ensembl chr 2:241,742,688...241,911,208
JBrowse link
G St6galnac6 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:10702226)
GO_Central
RGD
PMID:10702226 GO_REF:0000033 NCBI chr 3:15,894,275...15,907,502
Ensembl chr 3:15,885,968...15,907,496
JBrowse link
G St8sia2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 involved_in ISO (PMID:10766765) RGD PMID:10766765 NCBI chr 1:127,762,573...127,838,017
Ensembl chr 1:127,762,573...127,838,091
JBrowse link
G St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 involved_in ISO (PMID:10766765)
(MGI:74245|PMID:7782326)
RGD PMID:7782326 PMID:10766765 MGI:74245 NCBI chr18:57,754,349...57,760,839
Ensembl chr18:57,754,347...57,760,839
JBrowse link
G St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 involved_in ISO (PMID:10766765) RGD PMID:10766765 NCBI chr 9:95,990,131...96,084,661
Ensembl chr 9:95,993,503...96,084,653
JBrowse link
G St8sia6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 involved_in ISO (MGI:2182536|PMID:11980897) RGD PMID:11980897 MGI:2182536 NCBI chr17:76,740,755...76,884,178
Ensembl chr17:76,745,224...76,884,299
JBrowse link
ganglioside biosynthetic process via lactosylceramide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4galt5 beta-1,4-galactosyltransferase 5 involved_in ISO (MGI:6196231|PMID:30114188) RGD PMID:30114188 MGI:6196231 NCBI chr 3:156,018,056...156,033,983
Ensembl chr 3:156,018,053...156,070,074
JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 involved_in ISS
ISO
GO_REF:0000024
(MGI:6196231|PMID:30114188)
UniProt
RGD
PMID:30114188 GO_REF:0000024 MGI:6196231 NCBI chr18:11,958,382...12,015,247
Ensembl chr18:11,958,390...12,015,247
JBrowse link
G C3h20orf173 similar to human chromosome 20 open reading frame 173 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 3:144,514,060...144,524,979
Ensembl chr 3:144,519,930...144,524,920
JBrowse link
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 involved_in ISO
IBA
(PMID:8027041)
GO_REF:0000033
(MGI:65558|PMID:8144500)
RGD
GO_Central
PMID:8027041 PMID:8144500 GO_REF:0000033 MGI:65558 NCBI chr 7:98,845,270...98,913,409
Ensembl chr 7:98,845,270...98,913,236
JBrowse link
G St3gal2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 involved_in IDA
IBA
IEA
ISO
PMID:8144500
GO_REF:0000033
GO_REF:0000117
(MGI:6467685|PMID:22735313), (MGI:65558|PMID:8144500)
(PMID:8920913)
GO_Central
UniProt
RGD
PMID:8144500 PMID:8920913 PMID:22735313 PMID:8144500 GO_REF:0000033 GO_REF:0000117 MGI:6467685 MGI:65558, RGD:68307 NCBI chr19:38,888,851...38,939,874
Ensembl chr19:38,923,999...38,939,869
JBrowse link
G St3gal3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 involved_in IEA
ISO
GO_REF:0000107
(MGI:6467685|PMID:22735313)
Ensembl
RGD
PMID:22735313 GO_REF:0000107 MGI:6467685 NCBI chr 5:131,470,348...131,670,794
Ensembl chr 5:131,470,348...131,670,810
JBrowse link
globoside biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A4galt alpha 1,4-galactosyltransferase acts_upstream_of_or_within ISO MGI:3624807|MGI:5445373 (PMID:16476743), (PMID:22875802) RGD PMID:16476743 PMID:22875802 NCBI chr 7:114,368,525...114,392,872
Ensembl chr 7:114,368,276...114,396,071
JBrowse link
globoside biosynthetic process via lactosylceramide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G St3gal2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 involved_in ISO
ISS
IEA
(PMID:12716912)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:12716912 GO_REF:0000024 GO_REF:0000107 NCBI chr19:38,888,851...38,939,874
Ensembl chr19:38,923,999...38,939,869
JBrowse link
glucosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fa2h fatty acid 2-hydroxylase involved_in ISS
ISO
GO_REF:0000024
(MGI:5285470|PMID:21628453)
UniProt
RGD
PMID:21628453 GO_REF:0000024 MGI:5285470 NCBI chr19:39,312,904...39,364,153
Ensembl chr19:39,312,906...39,364,153
JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase involved_in ISO
IBA
ISS
(PMID:8643456)
GO_REF:0000033
(MGI:2180222|PMID:10430909), (MGI:3603060|PMID:16109770), (MGI:5448789|PMID:22851168), (MGI:5510915|PMID:23748427)
GO_REF:0000024
RGD
GO_Central
UniProt
PMID:8643456 PMID:10430909 PMID:16109770 PMID:22851168 PMID:23748427 GO_REF:0000024 GO_REF:0000033 MGI:2180222 MGI:3603060 MGI:5448789 MGI:5510915 NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393
JBrowse link
lactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4galt4 beta-1,4-galactosyltransferase 4 involved_in ISO
ISS
(PMID:9792633)
GO_REF:0000024
RGD
UniProt
PMID:9792633 GO_REF:0000024 NCBI chr11:61,995,807...62,021,751
Ensembl chr11:61,995,814...62,021,671
JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 involved_in ISO (PMID:10320813) RGD PMID:10320813 NCBI chr18:11,958,382...12,015,247
Ensembl chr18:11,958,390...12,015,247
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20292
    metabolic process 11720
      organic substance metabolic process 11221
        carbohydrate derivative metabolic process 1157
          carbohydrate derivative biosynthetic process 648
            glycolipid biosynthetic process 73
              glycosphingolipid biosynthetic process 32
                GSI anchor biosynthetic process + 0
                ganglioside biosynthetic process + 17
                globoside biosynthetic process + 2
                glycosylceramide biosynthetic process + 7
                isogloboside biosynthetic process 0
                lactosylceramide biosynthetic process 2
                mannosyl-inositol phosphorylceramide biosynthetic process 0
Path 2
Term Annotations click to browse term
  biological_process 20292
    metabolic process 11720
      primary metabolic process 10271
        lipid metabolic process 1483
          cellular lipid metabolic process 1100
            membrane lipid metabolic process 211
              sphingolipid metabolic process 158
                sphingolipid biosynthetic process 103
                  glycosphingolipid biosynthetic process 32
                    GSI anchor biosynthetic process + 0
                    ganglioside biosynthetic process + 17
                    globoside biosynthetic process + 2
                    glycosylceramide biosynthetic process + 7
                    isogloboside biosynthetic process 0
                    lactosylceramide biosynthetic process 2
                    mannosyl-inositol phosphorylceramide biosynthetic process 0
paths to the root