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ONTOLOGY REPORT - ANNOTATIONS

Term:glycosphingolipid biosynthetic process
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Accession:GO:0006688 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.
Synonyms:exact_synonym: glycosphingolipid anabolism;   glycosphingolipid biosynthesis;   glycosphingolipid formation;   glycosphingolipid synthesis


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glycosphingolipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A3galt2 alpha 1,3-galactosyltransferase 2 acts_upstream_of_or_within
involved_in		 IDA
ISO		 MGI:1347344|MGI:3512453 (MGI:5445364|PMID:22875802)
PMID:12626403
PMID:10854427		 RGD PMID:22875802 PMID:10854427 PMID:12626403 PMID:10854427 MGI:5445364, RGD:1299594, RGD:632674, RGD:1299594 NCBI chr 5:141,101,329...141,113,760
Ensembl chr 5:141,107,983...141,115,641 		JBrowse link
G B4galnt1 beta-1,4-N-acetyl-galactosaminyl transferase 1 involved_in IDA PMID:1606358 UniProt PMID:1606358 RGD:21201272 NCBI chr 7:62,988,429...62,996,190
Ensembl chr 7:62,988,930...62,996,190 		JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:9593693 PMID:21873635 RGD:70807, RGD:13792537 NCBI chr18:11,958,382...12,015,247
Ensembl chr18:11,958,390...12,015,247 		JBrowse link
G Fut4 fucosyltransferase 4 involved_in ISO
ISS		 (PMID:29593094)
GO_REF:0000024		 RGD
UniProt		 PMID:29593094 GO_REF:0000024 NCBI chr 8:11,586,721...11,590,682
Ensembl chr 8:11,586,721...11,590,682 		JBrowse link
G Fut4-ps1 fucosyltransferase 4, pseudogene 1 involved_in ISO (PMID:29593094) RGD PMID:29593094 NCBI chr 9:1,569,605...1,572,022 JBrowse link
G Fut9 fucosyltransferase 9 involved_in ISS
ISO		 GO_REF:0000024
(PMID:29593094)		 UniProt
RGD		 PMID:29593094 GO_REF:0000024 NCBI chr 5:39,351,815...39,565,256
Ensembl chr 5:39,351,819...39,565,130 		JBrowse link
G St6galnac5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 involved_in ISO (MGI:1346847|PMID:10521438) RGD PMID:10521438 MGI:1346847 NCBI chr 2:241,741,933...241,911,214
Ensembl chr 2:241,742,688...241,911,208 		JBrowse link
G St8sia5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 involved_in IDA PMID:1606358 UniProt PMID:1606358 RGD:21201272 NCBI chr18:70,736,632...70,802,537
Ensembl chr18:70,736,602...70,797,789 		JBrowse link
G Tm9sf2 transmembrane 9 superfamily member 2 involved_in ISO (PMID:30660999) RGD PMID:30660999 NCBI chr15:99,201,556...99,254,054
Ensembl chr15:99,201,489...99,254,049 		JBrowse link
G Ugt8 UDP glycosyltransferase 8 TAS RGD PMID:7521399 RGD:70050 NCBI chr 2:214,264,483...214,332,769
Ensembl chr 2:214,264,483...214,332,660 		JBrowse link
galactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3galt1 Beta-1,3-galactosyltransferase 1 involved_in ISO (PMID:9582303) RGD PMID:9582303 NCBI chr 3:52,253,413...52,826,508
Ensembl chr 3:52,253,618...52,825,313 		JBrowse link
G B3galt2 Beta-1,3-galactosyltransferase 2 involved_in ISO (PMID:9582303) RGD PMID:9582303 NCBI chr13:55,389,406...55,398,419
Ensembl chr13:55,389,406...55,398,419 		JBrowse link
G B4galt3 beta-1,4-galactosyltransferase 3 involved_in IBA
ISO		 PMID:21873635
(PMID:9405390)		 RGD PMID:9405390 PMID:21873635 RGD:13792537 NCBI chr13:83,691,378...83,697,448
Ensembl chr13:83,691,446...83,697,448 		JBrowse link
G Fa2h fatty acid 2-hydroxylase involved_in IMP
IEA
ISS
ISO		 PMID:17901466
GO_REF:0000041
GO_REF:0000024
(MGI:3696647|PMID:15658937), (MGI:3826747|PMID:18815260)		 UniProt
RGD		 PMID:15658937 PMID:18815260 PMID:17901466 GO_REF:0000024 GO_REF:0000041 MGI:3696647 MGI:3826747, RGD:13825191 NCBI chr19:39,312,904...39,364,153
Ensembl chr19:39,312,906...39,364,153 		JBrowse link
G Gal3st1 galactose-3-O-sulfotransferase 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:1355015|PMID:10727929)		 RGD PMID:10727929 PMID:21873635 MGI:1355015, RGD:13792537 NCBI chr14:78,868,049...78,886,402
Ensembl chr14:78,870,793...78,886,388 		JBrowse link
G Ugt8 UDP glycosyltransferase 8 involved_in IDA
IBA
IEA		 PMID:8713090
PMID:21873635
GO_REF:0000041		 UniProt PMID:8713090 PMID:21873635 GO_REF:0000041, RGD:39458006, RGD:13792537 NCBI chr 2:214,264,483...214,332,769
Ensembl chr 2:214,264,483...214,332,660 		JBrowse link
ganglioside biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3galt4 Beta-1,3-galactosyltransferase 4 involved_in ISO (PMID:9582303) RGD PMID:9582303 NCBI chr20:4,936,089...4,937,664
Ensembl chr20:4,931,768...4,938,315 		JBrowse link
G B4galnt1 beta-1,4-N-acetyl-galactosaminyl transferase 1 involved_in
acts_upstream_of_or_within		 IDA
ISO
ISS
IBA		 PMID:3140234
(PMID:1601877), (PMID:7487055), (PMID:7890749)
GO_REF:0000024
PMID:21873635
(MGI:83232|PMID:8855236)
MGI:2158349|MGI:96074 (MGI:1331265|PMID:10021458)		 RGD
UniProt		 PMID:1601877 PMID:7487055 PMID:7890749 PMID:8855236 PMID:10021458 More... GO_REF:0000024 MGI:1331265 MGI:83232, RGD:21201261, RGD:13792537 NCBI chr 7:62,988,429...62,996,190
Ensembl chr 7:62,988,930...62,996,190 		JBrowse link
G Rps18 ribosomal protein S18 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:4,931,427...4,935,538
Ensembl chr10:101,204,500...101,205,146
Ensembl chr20:101,204,500...101,205,146 		JBrowse link
G Rps18l1 ribosomal protein S18-like 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr10:101,204,519...101,205,067
Ensembl chr10:101,204,500...101,205,146 		JBrowse link
G St6galnac3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:242,129,755...242,645,120
Ensembl chr 2:242,129,763...242,645,133 		JBrowse link
G St6galnac4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:15,872,230...15,885,250
Ensembl chr 3:15,872,532...15,885,243 		JBrowse link
G St6galnac5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:241,741,933...241,911,214
Ensembl chr 2:241,742,688...241,911,208 		JBrowse link
G St6galnac6 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:1354410|PMID:10702226)
PMID:21873635		 RGD PMID:10702226 PMID:21873635 MGI:1354410, RGD:13792537 NCBI chr 3:15,894,278...15,907,502
Ensembl chr 3:15,885,968...15,907,496 		JBrowse link
G St8sia2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 involved_in ISO (PMID:10766765) RGD PMID:10766765 NCBI chr 1:127,766,669...127,838,017
Ensembl chr 1:127,762,573...127,838,091 		JBrowse link
G St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 involved_in ISO (PMID:10766765) RGD PMID:10766765 NCBI chr18:57,754,349...57,760,839
Ensembl chr18:57,754,347...57,760,839 		JBrowse link
G St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 involved_in ISO (PMID:10766765) RGD PMID:10766765 NCBI chr 9:95,994,150...96,084,617
Ensembl chr 9:95,993,503...96,084,653 		JBrowse link
G St8sia6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 involved_in ISO (MGI:2182536|PMID:11980897) RGD PMID:11980897 MGI:2182536 NCBI chr17:76,740,755...76,883,766
Ensembl chr17:76,745,224...76,884,299 		JBrowse link
ganglioside biosynthetic process via lactosylceramide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4galt5 beta-1,4-galactosyltransferase 5 involved_in ISO (MGI:6196231|PMID:30114188) RGD PMID:30114188 MGI:6196231 NCBI chr 3:156,018,056...156,033,983
Ensembl chr 3:156,018,053...156,070,074 		JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6196231|PMID:30114188)		 UniProt
RGD		 PMID:30114188 GO_REF:0000024 MGI:6196231 NCBI chr18:11,958,382...12,015,247
Ensembl chr18:11,958,390...12,015,247 		JBrowse link
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 involved_in ISO
IBA		 (PMID:8027041)
PMID:21873635
(MGI:65558|PMID:8144500)		 RGD PMID:8027041 PMID:8144500 PMID:21873635 MGI:65558, RGD:13792537 NCBI chr 7:98,845,270...98,913,409
Ensembl chr 7:98,845,270...98,913,236 		JBrowse link
G St3gal2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 involved_in IBA
ISO
IEA
IDA		 PMID:21873635
(PMID:8920913)
GO_REF:0000107
PMID:8144500
(MGI:6467685|PMID:22735313), (MGI:65558|PMID:8144500)		 RGD
Ensembl		 PMID:8144500 PMID:8920913 PMID:22735313 PMID:21873635 PMID:8144500 GO_REF:0000107 MGI:6467685 MGI:65558, RGD:13792537, RGD:68307 NCBI chr19:38,888,851...38,939,874
Ensembl chr19:38,923,999...38,939,869 		JBrowse link
G St3gal3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6467685|PMID:22735313)		 Ensembl
RGD		 PMID:22735313 GO_REF:0000107 MGI:6467685 NCBI chr 5:131,470,348...131,670,794
Ensembl chr 5:131,470,348...131,670,810 		JBrowse link
globoside biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A4galt alpha 1,4-galactosyltransferase (P blood group) acts_upstream_of_or_within ISO MGI:3624807|MGI:5445373 (MGI:3623723|PMID:16476743), (MGI:5445364|PMID:22875802) RGD PMID:16476743 PMID:22875802 MGI:3623723 MGI:5445364 NCBI chr 7:114,368,525...114,392,872
Ensembl chr 7:114,368,276...114,396,071 		JBrowse link
globoside biosynthetic process via lactosylceramide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G St3gal2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:12716912)		 UniProt
Ensembl
RGD		 PMID:12716912 GO_REF:0000024 GO_REF:0000107 NCBI chr19:38,888,851...38,939,874
Ensembl chr19:38,923,999...38,939,869 		JBrowse link
glucosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fa2h fatty acid 2-hydroxylase involved_in ISS
ISO		 GO_REF:0000024
(MGI:5285470|PMID:21628453)		 UniProt
RGD		 PMID:21628453 GO_REF:0000024 MGI:5285470 NCBI chr19:39,312,904...39,364,153
Ensembl chr19:39,312,906...39,364,153 		JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase involved_in ISS
ISO
IBA		 GO_REF:0000024
(PMID:8643456)
PMID:21873635
(MGI:2180222|PMID:10430909), (MGI:3603060|PMID:16109770), (MGI:5448789|PMID:22851168), (MGI:5510915|PMID:23748427)		 UniProt
RGD		 PMID:8643456 PMID:10430909 PMID:16109770 PMID:22851168 PMID:23748427 More... GO_REF:0000024 MGI:2180222 MGI:3603060 MGI:5448789 MGI:5510915, RGD:13792537 NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393 		JBrowse link
lactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4galt4 beta-1,4-galactosyltransferase 4 involved_in ISO
ISS		 (PMID:9792633)
GO_REF:0000024		 RGD
UniProt		 PMID:9792633 GO_REF:0000024 NCBI chr11:61,995,807...62,021,751
Ensembl chr11:61,995,814...62,021,671 		JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 involved_in ISO (PMID:10320813) RGD PMID:10320813 NCBI chr18:11,958,382...12,015,247
Ensembl chr18:11,958,390...12,015,247 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19746
    metabolic process 12044
      organic substance metabolic process 11597
        organic substance biosynthetic process 6173
          carbohydrate derivative biosynthetic process 644
            glycolipid biosynthetic process 72
              glycosphingolipid biosynthetic process 32
                GSI anchor biosynthetic process + 0
                ganglioside biosynthetic process + 17
                globoside biosynthetic process + 2
                glycosylceramide biosynthetic process + 7
                isogloboside biosynthetic process 0
                lactosylceramide biosynthetic process 2
                mannosyl-inositol phosphorylceramide biosynthetic process 0
Path 2
Term Annotations click to browse term
  biological_process 19746
    metabolic process 12044
      primary metabolic process 10824
        lipid metabolic process 1451
          cellular lipid metabolic process 1050
            membrane lipid metabolic process 202
              sphingolipid metabolic process 153
                sphingolipid biosynthetic process 102
                  glycosphingolipid biosynthetic process 32
                    GSI anchor biosynthetic process + 0
                    ganglioside biosynthetic process + 17
                    globoside biosynthetic process + 2
                    glycosylceramide biosynthetic process + 7
                    isogloboside biosynthetic process 0
                    lactosylceramide biosynthetic process 2
                    mannosyl-inositol phosphorylceramide biosynthetic process 0
paths to the root