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ONTOLOGY REPORT - ANNOTATIONS

Term:sphingolipid metabolic process
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Accession:GO:0006665 term browser browse the term
Definition:The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
Synonyms:exact_synonym: sphingolipid metabolism


show annotations for term's descendants           Sort by:
sphingolipid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acer1 alkaline ceramidase 1 acts_upstream_of_or_within ISO (MGI:2670497|PMID:12783875) RGD PMID:12783875 MGI:2670497 NCBI chr 9:1,794,340...1,824,432
Ensembl chr 9:1,793,139...1,824,434 		JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type involved_in ISO
ISS		 (PMID:21558561)
GO_REF:0000024		 RGD
UniProt		 PMID:21558561 GO_REF:0000024 NCBI chr10:53,863,060...53,874,938
Ensembl chr10:53,863,060...53,874,938 		JBrowse link
G Aloxe3 arachidonate lipoxygenase 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21558561)		 UniProt
RGD		 PMID:21558561 GO_REF:0000024 NCBI chr10:53,830,219...53,854,328
Ensembl chr10:53,831,264...53,854,328 		JBrowse link
G Arv1 ARV1 homolog, fatty acid homeostasis modulator involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:52,692,337...52,704,156
Ensembl chr19:52,692,337...52,704,156 		JBrowse link
G Cerkl ceramide kinase-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:64,238,714...64,344,695
Ensembl chr 3:64,237,522...64,340,675 		JBrowse link
G Fads3 fatty acid desaturase 3 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:206,685,667...206,702,538
Ensembl chr 1:206,685,894...206,704,769 		JBrowse link
G Gal3st1 galactose-3-O-sulfotransferase 1 involved_in ISO (PMID:8830034) RGD PMID:8830034 NCBI chr14:78,868,049...78,886,402
Ensembl chr14:78,870,793...78,886,388 		JBrowse link
G Psap prosaposin involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000104
MGI:2183897 (MGI:2183819|PMID:11371512)		 UniProt
RGD		 PMID:11371512 GO_REF:0000104 MGI:2183819 NCBI chr20:28,214,229...28,240,501
Ensembl chr20:28,214,271...28,240,498 		JBrowse link
G Psapl1 prosaposin-like 1 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr14:74,544,646...74,547,206
Ensembl chr14:74,544,646...74,547,206 		JBrowse link
G Serinc1 serine incorporator 1 involved_in IDA PMID:16120614 HGNC-UCL PMID:16120614 RGD:8553290 NCBI chr20:36,850,062...36,868,999
Ensembl chr20:36,850,076...36,896,691 		JBrowse link
G Serinc2 serine incorporator 2 involved_in ISS PMID:16120614 HGNC-UCL PMID:16120614 RGD:8553290 NCBI chr 5:142,592,308...142,614,628
Ensembl chr 5:142,592,309...142,618,364 		JBrowse link
G Serinc5 serine incorporator 5 involved_in ISS PMID:16120614 HGNC-UCL PMID:16120614 RGD:8553290 NCBI chr 2:23,846,899...23,950,346
Ensembl chr 2:23,846,900...23,950,346 		JBrowse link
G Sftpb surfactant protein B involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:104,359,303...104,368,439
Ensembl chr 4:104,359,396...104,368,436 		JBrowse link
G Sgms2 sphingomyelin synthase 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:219,889,809...219,967,704
Ensembl chr 2:219,893,572...219,967,546 		JBrowse link
G Sgpp1 sphingosine-1-phosphate phosphatase 1 acts_upstream_of_or_within ISO (MGI:1932564|PMID:10859351), (MGI:2386810|PMID:12235122) RGD PMID:10859351 PMID:12235122 MGI:1932564 MGI:2386810 NCBI chr 6:94,425,339...94,446,534
Ensembl chr 6:94,425,339...94,446,534 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1856877 (MGI:5469952|PMID:22945695)
GO_REF:0000041		 RGD
UniProt		 PMID:22945695 GO_REF:0000041 MGI:5469952 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749 		JBrowse link
G Spns2 SPNS lysolipid transporter 2, sphingosine-1-phosphate acts_upstream_of_or_within ISO MGI:4460276 (MGI:5490425|PMID:23180825) RGD PMID:23180825 MGI:5490425 NCBI chr10:57,067,348...57,105,969
Ensembl chr10:57,066,897...57,105,957 		JBrowse link
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 involved_in ISO (MGI:5896517|PMID:28100772) RGD PMID:28100772 MGI:5896517 NCBI chr17:11,877,249...11,916,295
Ensembl chr17:11,877,249...11,916,295 		JBrowse link
G Tecr trans-2,3-enoyl-CoA reductase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
GO_REF:0000041
(PMID:25049234)		 UniProt
Ensembl
RGD		 PMID:25049234 GO_REF:0000024 GO_REF:0000041 GO_REF:0000107 NCBI chr19:24,526,700...24,568,168
Ensembl chr19:24,541,615...24,568,168 		JBrowse link
G Th tyrosine hydroxylase IEP sphingosine 1-phosphate RGD PMID:21076868 RGD:5128811 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
G Zpbp2 zona pellucida binding protein 2 acts_upstream_of_or_within ISO MGI:3762590 (MGI:6150730|PMID:29536159) RGD PMID:29536159 MGI:6150730 NCBI chr10:83,558,772...83,567,511
Ensembl chr10:83,559,016...83,567,508 		JBrowse link
3-keto-sphinganine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdsr 3-ketodihydrosphingosine reductase involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(PMID:15364918)		 RGD PMID:15364918 PMID:21873635 RGD:13792537 NCBI chr13:22,862,117...22,894,118
Ensembl chr13:22,862,117...22,894,108 		JBrowse link
ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agk acylglycerol kinase involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:3054595|PMID:15252046)		 RGD PMID:15252046 PMID:21873635 MGI:3054595, RGD:13792537 NCBI chr 4:69,114,850...69,193,989
Ensembl chr 4:69,114,269...69,193,934 		JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:3789553|PMID:17403930)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:17403930 GO_REF:0000024 GO_REF:0000107 MGI:3789553 NCBI chr10:53,863,060...53,874,938
Ensembl chr10:53,863,060...53,874,938 		JBrowse link
G Aloxe3 arachidonate lipoxygenase 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5488571|PMID:22832496)		 UniProt
RGD		 PMID:22832496 GO_REF:0000024 MGI:5488571 NCBI chr10:53,830,219...53,854,328
Ensembl chr10:53,831,264...53,854,328 		JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 involved_in ISO
ISS		 (PMID:12764132), (PMID:12815059)
GO_REF:0000024		 RGD
UniProt		 PMID:12764132 PMID:12815059 GO_REF:0000024 NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233 		JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in ISO
IDA		 (PMID:11278489), (PMID:17475390)
(MGI:6274955|PMID:21613224)
PMID:15123644		 RGD PMID:11278489 PMID:17475390 PMID:21613224 PMID:15123644 PMID:11278489 MGI:6274955, RGD:13838793, RGD:13838803 NCBI chr 1:229,865,662...229,973,253
Ensembl chr 1:229,865,662...229,939,162 		JBrowse link
G Cers1 ceramide synthase 1 involved_in ISO
IBA		 (PMID:12105227), (PMID:12869556), (PMID:15823095), (PMID:17548428), (PMID:18541923), (PMID:22922758), (PMID:24782409)
PMID:21873635
(MGI:3696321|PMID:16951403), (MGI:3764760|PMID:17977534), (MGI:5008665|PMID:21625621), (MGI:5755322|PMID:26620563), (MGI:6380950|PMID:30605666)		 RGD PMID:12105227 PMID:12869556 PMID:15823095 PMID:16951403 PMID:17548428 More... MGI:3696321 MGI:3764760 MGI:5008665 MGI:5755322 MGI:6380950, RGD:13792537 NCBI chr16:19,097,309...19,112,519
Ensembl chr16:19,104,466...19,112,519 		JBrowse link
G Cers2 ceramide synthase 2 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:17977534), (PMID:18165233), (PMID:29632068)
PMID:21873635
(MGI:4421488|PMID:19801672), (MGI:5755322|PMID:26620563)
(MGI:3696894|PMID:15823095)		 RGD PMID:15823095 PMID:17977534 PMID:18165233 PMID:19801672 PMID:26620563 More... MGI:3696894 MGI:4421488 MGI:5755322, RGD:13792537 NCBI chr 2:182,890,527...182,898,805
Ensembl chr 2:182,890,493...182,933,314 		JBrowse link
G Cers3 ceramide synthase 3 involved_in ISO
IBA		 (PMID:17977534), (PMID:22038835), (PMID:23754960)
PMID:21873635
(MGI:5303015|PMID:22038835)		 RGD PMID:17977534 PMID:22038835 PMID:23754960 PMID:21873635 MGI:5303015, RGD:13792537 NCBI chr 1:120,316,930...120,422,926
Ensembl chr 1:120,318,212...120,422,902 		JBrowse link
G Cers4 ceramide synthase 4 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:17977534), (PMID:29632068)
PMID:21873635
(MGI:2679796|PMID:12912983), (MGI:3696894|PMID:15823095)		 RGD PMID:12912983 PMID:15823095 PMID:17977534 PMID:29632068 PMID:21873635 MGI:2679796 MGI:3696894, RGD:13792537 NCBI chr12:2,851,784...2,890,244
Ensembl chr12:2,851,784...2,886,828 		JBrowse link
G Cers5 ceramide synthase 5 involved_in ISO
IBA		 (PMID:16951403), (PMID:29632068)
PMID:21873635
(MGI:3696624|PMID:16100120), (MGI:3722529|PMID:17609214), (MGI:3764760|PMID:17977534)		 RGD PMID:16100120 PMID:16951403 PMID:17609214 PMID:17977534 PMID:29632068 More... MGI:3696624 MGI:3722529 MGI:3764760, RGD:13792537 NCBI chr 7:130,859,993...130,897,979
Ensembl chr 7:130,859,990...130,897,947 		JBrowse link
G Cers6 ceramide synthase 6 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:17609214), (PMID:17977534)
PMID:21873635
(MGI:5513027|PMID:23760501), (MGI:5755322|PMID:26620563)
(MGI:3696894|PMID:15823095)		 RGD PMID:15823095 PMID:17609214 PMID:17977534 PMID:23760501 PMID:26620563 More... MGI:3696894 MGI:5513027 MGI:5755322, RGD:13792537 NCBI chr 3:53,630,637...53,879,692
Ensembl chr 3:53,630,959...53,876,848 		JBrowse link
G Cyp4f17 cytochrome P450, family 4, subfamily f, polypeptide 17 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:11,518,985...11,536,208
Ensembl chr 7:11,433,371...11,536,181 		JBrowse link
G Cyp4f39 cytochrome P450, family 4, subfamily f, polypeptide 39 involved_in IBA
ISO		 PMID:21873635
(PMID:26056268)		 RGD PMID:26056268 PMID:21873635 RGD:13792537 NCBI chr 7:11,426,806...11,505,553
Ensembl chr 7:11,433,371...11,536,181 		JBrowse link
G Degs1 delta(4)-desaturase, sphingolipid 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:3529540 (MGI:5466789|PMID:22984457)
PMID:21873635		 RGD PMID:22984457 PMID:21873635 MGI:5466789, RGD:13792537 NCBI chr13:93,946,154...93,953,677
Ensembl chr13:93,946,157...93,953,664 		JBrowse link
G Degs1l1 delta(4)-desaturase, sphingolipid 1 like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:92,772,654...92,818,811
Ensembl chr13:92,772,649...92,818,574 		JBrowse link
G Degs1l2 delta(4)-desaturase, sphingolipid 1 like 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:92,831,549...92,839,257
Ensembl chr13:92,831,537...92,839,246 		JBrowse link
G Degs2 delta(4)-desaturase, sphingolipid 2 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:3694278|PMID:16571104)
PMID:21873635		 RGD PMID:16571104 PMID:21873635 MGI:3694278, RGD:13792537 NCBI chr 6:127,596,063...127,613,293
Ensembl chr 6:127,596,071...127,613,293 		JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 involved_in ISO (MGI:5532629|PMID:23689133) RGD PMID:23689133 MGI:5532629 NCBI chr 5:131,961,478...131,965,961
Ensembl chr 5:131,961,322...131,965,958 		JBrowse link
G Fa2h fatty acid 2-hydroxylase involved_in ISO
ISS		 (PMID:15337768)
(MGI:6245295|PMID:22517924)
GO_REF:0000024		 RGD
UniProt		 PMID:15337768 PMID:22517924 GO_REF:0000024 MGI:6245295 NCBI chr19:39,312,904...39,364,153
Ensembl chr19:39,312,906...39,364,153 		JBrowse link
G Gba1 glucosylceramidase beta 1 involved_in ISO (PMID:19279011) RGD PMID:19279011 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263 		JBrowse link
G P2rx1 purinergic receptor P2X 1 acts_upstream_of_or_within ISO (MGI:3640029|PMID:16325464) RGD PMID:16325464 MGI:3640029 NCBI chr10:57,618,586...57,633,648
Ensembl chr10:57,618,586...57,633,623 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (MGI:3640029|PMID:16325464) RGD PMID:16325464 MGI:3640029 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G Pnpla1 patatin-like phospholipase domain containing 1 involved_in ISO (PMID:27751867)
(MGI:5882269|PMID:27751867)		 RGD PMID:27751867 MGI:5882269 NCBI chr20:6,917,993...6,952,157
Ensembl chr20:6,917,931...6,952,375 		JBrowse link
G Samd8 sterile alpha motif domain containing 8 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:19506037)
PMID:21873635
MGI:5749225 (MGI:5632043|PMID:25605874), (MGI:5707904|PMID:25667419)		 RGD PMID:19506037 PMID:25605874 PMID:25667419 PMID:21873635 MGI:5632043 MGI:5707904, RGD:13792537 NCBI chr15:2,512,104...2,562,368
Ensembl chr15:2,512,105...2,515,379
Ensembl chr15:2,512,105...2,515,379 		JBrowse link
G Sgms1 sphingomyelin synthase 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(PMID:25605874)
(MGI:5632043|PMID:25605874)		 RGD PMID:25605874 PMID:21873635 MGI:5632043, RGD:13792537 NCBI chr 1:229,996,673...230,259,591
Ensembl chr 1:229,998,119...230,259,603 		JBrowse link
G Sgms2 sphingomyelin synthase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
MGI:4818459 (MGI:5632043|PMID:25605874)
PMID:21873635		 Ensembl
RGD		 PMID:25605874 PMID:21873635 GO_REF:0000107 MGI:5632043, RGD:13792537 NCBI chr 2:219,889,809...219,967,704
Ensembl chr 2:219,893,572...219,967,546 		JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 involved_in IMP
ISO
IBA		 (PMID:17303575), (PMID:18815062), (PMID:19279011), (PMID:20807762), (PMID:33163980), (PMID:8706124)
(MGI:7327228|PMID:35705808), (MGI:82530|PMID:8706124)
PMID:21873635		 RGD PMID:8706124 PMID:17303575 PMID:18815062 PMID:19279011 PMID:20807762 More... MGI:7327228 MGI:82530, RGD:1601344, RGD:13792537 NCBI chr 1:159,892,946...159,896,789
Ensembl chr 1:159,892,859...159,896,794 		JBrowse link
G Smpd2 sphingomyelin phosphodiesterase 2 involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:12473648 PMID:21873635 RGD:1581395, RGD:13792537 NCBI chr20:44,986,229...44,989,343
Ensembl chr20:44,986,231...44,989,441 		JBrowse link
G Smpd4 sphingomyelin phosphodiesterase 4 involved_in ISO
IBA		 (PMID:16517606), (PMID:25180167)
(MGI:6450503|PMID:25180167)
PMID:21873635		 RGD PMID:16517606 PMID:25180167 PMID:21873635 MGI:6450503, RGD:13792537 NCBI chr11:83,362,534...83,386,257
Ensembl chr11:83,362,534...83,386,250 		JBrowse link
G Smpd5 sphingomyelin phosphodiesterase 5 involved_in ISO (MGI:6450238|PMID:21183079) RGD PMID:21183079 MGI:6450238 NCBI chr 7:108,009,182...108,011,767
Ensembl chr 7:108,009,173...108,011,763 		JBrowse link
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(PMID:25691431)
MGI:3815115 (MGI:3814228|PMID:16216550)		 RGD PMID:16216550 PMID:25691431 PMID:21873635 MGI:3814228, RGD:13792537 NCBI chr17:11,877,249...11,916,295
Ensembl chr17:11,877,249...11,916,295 		JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 PMID:21873635
GO_REF:0000107
(PMID:25691431)
MGI:3815117 (MGI:3814228|PMID:16216550)		 Ensembl
RGD		 PMID:16216550 PMID:25691431 PMID:21873635 GO_REF:0000107 MGI:3814228, RGD:13792537 NCBI chr 6:106,948,682...107,031,532
Ensembl chr 6:106,950,949...107,031,542 		JBrowse link
G Sptlc3 serine palmitoyltransferase, long chain base subunit 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:126,847,878...126,978,010
Ensembl chr 3:126,847,878...126,978,010 		JBrowse link
G Sptssa serine palmitoyltransferase, small subunit A involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(PMID:25691431)		 RGD PMID:25691431 PMID:21873635 RGD:13792537 NCBI chr 6:72,144,714...72,156,130
Ensembl chr 6:72,144,714...72,156,214 		JBrowse link
G Sptssb serine palmitoyltransferase, small subunit B acts_upstream_of_or_within ISO MGI:5689843 (MGI:5689923|PMID:26438849) RGD PMID:26438849 MGI:5689923 NCBI chr 2:154,133,728...154,162,127
Ensembl chr 2:154,133,733...154,163,120 		JBrowse link
G Tlcd3b TLC domain containing 3B acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:5490837|PMID:23275342)
PMID:21873635		 RGD PMID:23275342 PMID:21873635 MGI:5490837, RGD:13792537 NCBI chr 1:181,421,104...181,439,744
Ensembl chr 1:181,422,830...181,439,743 		JBrowse link
ceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acer1 alkaline ceramidase 1 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:20207939)
PMID:21873635
(MGI:2670497|PMID:12783875)
(MGI:5800647|PMID:27126290)		 RGD PMID:12783875 PMID:20207939 PMID:27126290 PMID:21873635 MGI:2670497 MGI:5800647, RGD:13792537 NCBI chr 9:1,794,340...1,824,432
Ensembl chr 9:1,793,139...1,824,434 		JBrowse link
G Acer2 alkaline ceramidase 2 involved_in ISO
IBA		 (PMID:16940153), (PMID:20207939)
PMID:21873635		 RGD PMID:16940153 PMID:20207939 PMID:21873635 RGD:13792537 NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614 		JBrowse link
G Acer3 alkaline ceramidase 3 involved_in ISO (PMID:20207939), (PMID:26792856), (PMID:30575723)
(MGI:5749603|PMID:26474409)		 RGD PMID:20207939 PMID:26474409 PMID:26792856 PMID:30575723 MGI:5749603 NCBI chr 1:152,504,180...152,606,596
Ensembl chr 1:152,504,186...152,606,591 		JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:1267186|PMID:9653654), (MGI:5505361|PMID:23770692)
(PMID:10610716), (PMID:12815059)		 UniProt
Ensembl
RGD		 PMID:9653654 PMID:10610716 PMID:12815059 PMID:23770692 GO_REF:0000024 GO_REF:0000107 MGI:1267186 MGI:5505361 NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233 		JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in IDA
IEA
ISO
IBA		 PMID:10488143
GO_REF:0000002
PMID:15123644
(MGI:3608219|PMID:16126722), (MGI:3640407|PMID:16380386), (MGI:6275120|PMID:10652340)
PMID:15217782
PMID:21873635
(PMID:10781606), (PMID:15946935), (PMID:16229686), (PMID:17475390), (PMID:19345744), (PMID:30154232)		 InterPro
RGD		 PMID:10652340 PMID:10781606 PMID:15946935 PMID:16126722 PMID:16229686 More... GO_REF:0000002 MGI:3608219 MGI:3640407 MGI:6275120, RGD:13838800, RGD:13838793, RGD:13838794, RGD:13792537 NCBI chr 1:229,865,662...229,973,253
Ensembl chr 1:229,865,662...229,939,162 		JBrowse link
G Cel carboxyl ester lipase involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 GO_REF:0000107
PMID:21873635
MGI:2180867 (MGI:2158596|PMID:11733511)		 Ensembl
RGD		 PMID:11733511 PMID:21873635 GO_REF:0000107 MGI:2158596, RGD:13792537 NCBI chr 3:11,883,532...11,891,035
Ensembl chr 3:11,883,532...11,891,035 		JBrowse link
ceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca12 ATP binding cassette subfamily A member 12 involved_in ISO (PMID:17927575)
(MGI:4462766|PMID:20489143)		 RGD PMID:17927575 PMID:20489143 MGI:4462766 NCBI chr 9:72,822,661...72,995,748
Ensembl chr 9:72,823,350...72,996,049 		JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:26190575)		 UniProt
RGD		 PMID:26190575 GO_REF:0000024 NCBI chr 1:229,865,662...229,973,253
Ensembl chr 1:229,865,662...229,939,162 		JBrowse link
G Cerk ceramide kinase involved_in ISO
IBA		 (PMID:19501188)
PMID:21873635		 RGD PMID:19501188 PMID:21873635 RGD:13792537 NCBI chr 7:117,225,855...117,269,436
Ensembl chr 7:117,225,855...117,268,759 		JBrowse link
G Cert1 ceramide transporter 1 acts_upstream_of_or_within ISO MGI:3837565 (MGI:3836857|PMID:19139267) RGD PMID:19139267 MGI:3836857 NCBI chr 2:27,882,546...27,987,090
Ensembl chr 2:27,882,555...27,987,074 		JBrowse link
G Cln8 CLN8, transmembrane ER and ERGIC protein involved_in ISS
ISO		 GO_REF:0000024
(PMID:16086686)		 UniProt
RGD		 PMID:16086686 GO_REF:0000024 NCBI chr16:74,749,662...74,759,553
Ensembl chr16:74,749,662...74,759,774 		JBrowse link
G ENSRNOG00000069695 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr14:25,729,638...25,730,194 JBrowse link
G Fut4-ps1 fucosyltransferase 4, pseudogene 1 involved_in ISO (PMID:17604274) RGD PMID:17604274 NCBI chr 9:1,569,605...1,572,022 JBrowse link
G Fut7 fucosyltransferase 7 involved_in ISO (PMID:9299472) RGD PMID:9299472 NCBI chr 3:8,237,687...8,242,273
Ensembl chr 3:8,239,384...8,242,260 		JBrowse link
G Htra2 HtrA serine peptidase 2 IEP C2 ceramide RGD PMID:22296759 RGD:5688365 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095 		JBrowse link
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 involved_in IBA
ISO		 PMID:21873635
(PMID:20182505)		 RGD PMID:20182505 PMID:21873635 RGD:13792537 NCBI chr 9:48,243,365...48,253,316
Ensembl chr 9:48,237,572...48,253,211 		JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 involved_in ISO
IBA		 (PMID:20182505)
PMID:21873635		 RGD PMID:20182505 PMID:21873635 RGD:13792537 NCBI chr 7:1,247,869...1,250,999
Ensembl chr 7:1,246,479...1,250,907 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 involved_in ISO
IEA
IBA
ISS		 (PMID:20182505)
GO_REF:0000107
PMID:21873635
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:20182505 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr10:83,590,052...83,596,035
Ensembl chr10:83,590,071...83,598,620 		JBrowse link
G Pla2g15 phospholipase A2, group XV involved_in
acts_upstream_of_or_within		 ISO
IDA
IBA		 (PMID:20410020), (PMID:29724779)
PMID:15294901
PMID:21873635
(MGI:3694368|PMID:16837646), (MGI:4820669|PMID:20410020)
(MGI:2176649|PMID:11790796)		 RGD PMID:11790796 PMID:16837646 PMID:20410020 PMID:29724779 PMID:15294901 More... MGI:2176649 MGI:3694368 MGI:4820669, RGD:1304489, RGD:13792537 NCBI chr19:34,050,685...34,068,070
Ensembl chr19:34,050,694...34,068,063 		JBrowse link
G Plpp1 phospholipid phosphatase 1 involved_in IDA
IEA
ISO		 PMID:8663293
GO_REF:0000107
(MGI:6383560|PMID:10359651)
(PMID:9305923), (PMID:9705349)		 Ensembl
RGD		 PMID:9305923 PMID:9705349 PMID:10359651 PMID:8663293 PMID:10359651 GO_REF:0000107 MGI:6383560, RGD:15090855, RGD:15090857 NCBI chr 2:44,439,002...44,500,430
Ensembl chr 2:44,438,994...44,501,268 		JBrowse link
G Plpp2 phospholipid phosphatase 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:9705349)		 UniProt
RGD		 PMID:9705349 GO_REF:0000024 NCBI chr 7:10,175,918...10,184,032
Ensembl chr 7:10,175,948...10,184,071 		JBrowse link
G Plpp3 phospholipid phosphatase 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:9305923), (PMID:9705349)		 UniProt
RGD		 PMID:9305923 PMID:9705349 GO_REF:0000024 NCBI chr 5:119,927,085...120,002,206
Ensembl chr 5:119,927,085...120,002,205 		JBrowse link
G Psap prosaposin acts_upstream_of_or_within ISO MGI:3521746 (MGI:3512714|PMID:15345707), (MGI:3711591|PMID:17353235) RGD PMID:15345707 PMID:17353235 MGI:3512714 MGI:3711591 NCBI chr20:28,214,229...28,240,501
Ensembl chr20:28,214,271...28,240,498 		JBrowse link
G Sgpl1 sphingosine-1-phosphate lyase 1 involved_in ISO
IEA
ISS		 (PMID:14570870)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:14570870 GO_REF:0000024 GO_REF:0000107 NCBI chr20:29,047,793...29,094,209
Ensembl chr20:29,047,796...29,094,084 		JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 acts_upstream_of_or_within ISO MGI:2183206 (MGI:5448760|PMID:23046545) RGD PMID:23046545 MGI:5448760 NCBI chr 1:159,892,946...159,896,789
Ensembl chr 1:159,892,859...159,896,794 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1856877 (MGI:5320806|PMID:22383528), (MGI:5448760|PMID:23046545)		 Ensembl
RGD		 PMID:22383528 PMID:23046545 GO_REF:0000107 MGI:5320806 MGI:5448760 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749 		JBrowse link
G Smpd5 sphingomyelin phosphodiesterase 5 acts_upstream_of_or_within ISO (MGI:4833930|PMID:20378533) RGD PMID:20378533 MGI:4833930 NCBI chr 7:108,009,182...108,011,767
Ensembl chr 7:108,009,173...108,011,763 		JBrowse link
G Tm9sf2 transmembrane 9 superfamily member 2 involved_in ISO (PMID:30660999) RGD PMID:30660999 NCBI chr15:99,201,556...99,254,054
Ensembl chr15:99,201,489...99,254,049 		JBrowse link
ceramide phosphoethanolamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Samd8 sterile alpha motif domain containing 8 acts_upstream_of_or_within ISO (MGI:5707904|PMID:25667419) RGD PMID:25667419 MGI:5707904 NCBI chr15:2,512,104...2,562,368
Ensembl chr15:2,512,105...2,515,379
Ensembl chr15:2,512,105...2,515,379 		JBrowse link
G Sgms2 sphingomyelin synthase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:5707904|PMID:25667419)		 Ensembl
RGD		 PMID:25667419 GO_REF:0000107 MGI:5707904 NCBI chr 2:219,889,809...219,967,704
Ensembl chr 2:219,893,572...219,967,546 		JBrowse link
galactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3galt1 Beta-1,3-galactosyltransferase 1 involved_in ISO (PMID:9582303) RGD PMID:9582303 NCBI chr 3:52,253,413...52,826,508
Ensembl chr 3:52,253,618...52,825,313 		JBrowse link
G B3galt2 Beta-1,3-galactosyltransferase 2 involved_in ISO (PMID:9582303) RGD PMID:9582303 NCBI chr13:55,389,406...55,398,419
Ensembl chr13:55,389,406...55,398,419 		JBrowse link
G B4galt3 beta-1,4-galactosyltransferase 3 involved_in IBA
IEA
ISO		 PMID:21873635
GO_REF:0000107
(PMID:9405390)		 Ensembl
RGD		 PMID:9405390 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr13:83,691,378...83,697,448
Ensembl chr13:83,691,446...83,697,448 		JBrowse link
G Fa2h fatty acid 2-hydroxylase involved_in ISS
ISO
IMP
IEA		 GO_REF:0000024
(MGI:3696647|PMID:15658937), (MGI:3826747|PMID:18815260)
PMID:17901466
GO_REF:0000041		 UniProt
RGD		 PMID:15658937 PMID:18815260 PMID:17901466 GO_REF:0000024 GO_REF:0000041 MGI:3696647 MGI:3826747, RGD:13825191 NCBI chr19:39,312,904...39,364,153
Ensembl chr19:39,312,906...39,364,153 		JBrowse link
G Gal3st1 galactose-3-O-sulfotransferase 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:1355015|PMID:10727929)		 RGD PMID:10727929 PMID:21873635 MGI:1355015, RGD:13792537 NCBI chr14:78,868,049...78,886,402
Ensembl chr14:78,870,793...78,886,388 		JBrowse link
G Ugt8 UDP glycosyltransferase 8 involved_in IDA
IBA
IEA		 PMID:8713090
PMID:21873635
GO_REF:0000041		 UniProt PMID:8713090 PMID:21873635 GO_REF:0000041, RGD:39458006, RGD:13792537 NCBI chr 2:214,264,483...214,332,769
Ensembl chr 2:214,264,483...214,332,660 		JBrowse link
galactosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Galc galactosylceramidase involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:78941|PMID:8769874)
MGI:1856218 (MGI:2183819|PMID:11371512)
(PMID:8399327)		 RGD PMID:8399327 PMID:8769874 PMID:11371512 PMID:21873635 MGI:2183819 MGI:78941, RGD:13792537 NCBI chr 6:117,452,888...117,522,281
Ensembl chr 6:117,452,895...117,515,830 		JBrowse link
G Gba3 glucosylceramidase beta 3 involved_in ISO (PMID:17595169) RGD PMID:17595169 NCBI chr14:60,574,974...60,721,411
Ensembl chr14:60,574,976...60,721,653 		JBrowse link
G Psap prosaposin acts_upstream_of_or_within ISO MGI:2183897 (MGI:2183819|PMID:11371512) RGD PMID:11371512 MGI:2183819 NCBI chr20:28,214,229...28,240,501
Ensembl chr20:28,214,271...28,240,498 		JBrowse link
galactosylceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gal3st1 galactose-3-O-sulfotransferase 1 involved_in ISO (MGI:6436415|PMID:9030544) RGD PMID:9030544 MGI:6436415 NCBI chr14:78,868,049...78,886,402
Ensembl chr14:78,870,793...78,886,388 		JBrowse link
ganglioside biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3galt4 Beta-1,3-galactosyltransferase 4 involved_in ISO
IEA		 (PMID:9582303)
GO_REF:0000107		 RGD
Ensembl		 PMID:9582303 GO_REF:0000107 NCBI chr20:4,936,089...4,937,664
Ensembl chr20:4,931,768...4,938,315 		JBrowse link
G B4galnt1 beta-1,4-N-acetyl-galactosaminyl transferase 1 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO
IDA
ISS		 PMID:21873635
GO_REF:0000107
(MGI:83232|PMID:8855236)
MGI:2158349|MGI:96074 (MGI:1331265|PMID:10021458)
PMID:3140234
(PMID:1601877), (PMID:7487055), (PMID:7890749)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:1601877 PMID:7487055 PMID:7890749 PMID:8855236 PMID:10021458 More... GO_REF:0000024 GO_REF:0000107 MGI:1331265 MGI:83232, RGD:13792537, RGD:21201261 NCBI chr 7:62,988,429...62,996,190
Ensembl chr 7:62,988,930...62,996,190 		JBrowse link
G Rps18 ribosomal protein S18 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:4,931,427...4,935,538
Ensembl chr10:101,204,500...101,205,146
Ensembl chr20:101,204,500...101,205,146 		JBrowse link
G St6galnac3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:242,129,755...242,645,120
Ensembl chr 2:242,129,763...242,645,133 		JBrowse link
G St6galnac4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:15,872,230...15,885,250
Ensembl chr 3:15,872,532...15,885,243 		JBrowse link
G St6galnac5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:241,741,933...241,911,214
Ensembl chr 2:241,742,688...241,911,208 		JBrowse link
G St6galnac6 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:1354410|PMID:10702226)
PMID:21873635		 RGD PMID:10702226 PMID:21873635 MGI:1354410, RGD:13792537 NCBI chr 3:15,894,275...15,907,502
Ensembl chr 3:15,885,968...15,907,496 		JBrowse link
G St8sia2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 involved_in ISO (PMID:10766765) RGD PMID:10766765 NCBI chr 1:127,762,573...127,838,017
Ensembl chr 1:127,762,573...127,838,091 		JBrowse link
G St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 involved_in ISO (PMID:10766765) RGD PMID:10766765 NCBI chr18:57,754,349...57,760,839
Ensembl chr18:57,754,347...57,760,839 		JBrowse link
G St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 involved_in ISO (PMID:10766765) RGD PMID:10766765 NCBI chr 9:95,990,131...96,084,661
Ensembl chr 9:95,993,503...96,084,653 		JBrowse link
G St8sia6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 involved_in ISO (MGI:2182536|PMID:11980897) RGD PMID:11980897 MGI:2182536 NCBI chr17:76,740,755...76,884,178
Ensembl chr17:76,745,224...76,884,299 		JBrowse link
ganglioside biosynthetic process via lactosylceramide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4galt5 beta-1,4-galactosyltransferase 5 involved_in ISO (MGI:6196231|PMID:30114188) RGD PMID:30114188 MGI:6196231 NCBI chr 3:156,018,056...156,033,983
Ensembl chr 3:156,018,053...156,070,074 		JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6196231|PMID:30114188)		 UniProt
RGD		 PMID:30114188 GO_REF:0000024 MGI:6196231 NCBI chr18:11,958,382...12,015,247
Ensembl chr18:11,958,390...12,015,247 		JBrowse link
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 involved_in ISO
IBA		 (PMID:8027041)
PMID:21873635
(MGI:65558|PMID:8144500)		 RGD PMID:8027041 PMID:8144500 PMID:21873635 MGI:65558, RGD:13792537 NCBI chr 7:98,845,270...98,913,409
Ensembl chr 7:98,845,270...98,913,236 		JBrowse link
G St3gal2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 involved_in IDA
IBA
IEA
ISO		 PMID:8144500
PMID:21873635
GO_REF:0000107
(MGI:6467685|PMID:22735313), (MGI:65558|PMID:8144500)
(PMID:8920913)		 Ensembl
RGD		 PMID:8144500 PMID:8920913 PMID:22735313 PMID:8144500 PMID:21873635 GO_REF:0000107 MGI:6467685 MGI:65558, RGD:68307, RGD:13792537 NCBI chr19:38,888,851...38,939,874
Ensembl chr19:38,923,999...38,939,869 		JBrowse link
G St3gal3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6467685|PMID:22735313)		 Ensembl
RGD		 PMID:22735313 GO_REF:0000107 MGI:6467685 NCBI chr 5:131,470,348...131,670,794
Ensembl chr 5:131,470,348...131,670,810 		JBrowse link
ganglioside catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gm2a ganglioside GM2 activator acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:1861930 (MGI:894862|PMID:9223328)
PMID:21873635		 RGD PMID:9223328 PMID:21873635 MGI:894862, RGD:13792537 NCBI chr10:39,219,221...39,231,756
Ensembl chr10:39,219,243...39,231,757 		JBrowse link
G Hexa hexosaminidase subunit alpha involved_in
acts_upstream_of_or_within		 ISS
IBA
ISO		 GO_REF:0000024
PMID:21873635
MGI:1857181|MGI:2429698 (MGI:1271008|PMID:9645704), (MGI:69059|PMID:7937929), (MGI:78473|PMID:8789434), (MGI:894862|PMID:9223328)
(PMID:8123671), (PMID:8672428), (PMID:9694901)		 UniProt
RGD		 PMID:7937929 PMID:8123671 PMID:8672428 PMID:8789434 PMID:9223328 More... GO_REF:0000024 MGI:1271008 MGI:69059 MGI:78473 MGI:894862, RGD:13792537 NCBI chr 8:59,936,526...59,961,654
Ensembl chr 8:59,936,660...59,962,013 		JBrowse link
G Hexb hexosaminidase subunit beta involved_in
acts_upstream_of_or_within		 ISS
IBA
ISO
IEA		 GO_REF:0000024
PMID:21873635
MGI:1857438|MGI:2429701 (MGI:1271008|PMID:9645704), (MGI:1331265|PMID:10021458), (MGI:2670850|PMID:12756243), (MGI:3041658|PMID:12657883), (MGI:3573807|PMID:15748167), (MGI:76816|PMID:8566348), (MGI:78473|PMID:8789434), (MGI:894862|PMID:9223328)
(PMID:8123671), (PMID:8672428)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:8123671 PMID:8566348 PMID:8672428 PMID:8789434 PMID:9223328 More... GO_REF:0000024 GO_REF:0000107 MGI:1271008 MGI:1331265 MGI:2670850 MGI:3041658 MGI:3573807 MGI:76816 MGI:78473 MGI:894862, RGD:13792537 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223 		JBrowse link
G Neu1 neuraminidase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:3,897,480...3,901,745
Ensembl chr20:3,897,480...3,901,745 		JBrowse link
G Neu2 neuraminidase 2 involved_in ISS
IEA
ISO
IBA		 GO_REF:0000024
GO_REF:0000107
(MGI:1354405|PMID:10713120)
(PMID:14613940), (PMID:22228546)
PMID:21873635		 UniProt
Ensembl
RGD		 PMID:10713120 PMID:14613940 PMID:22228546 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:1354405, RGD:13792537 NCBI chr 9:88,218,494...88,267,356
Ensembl chr 9:88,249,135...88,267,355 		JBrowse link
G Neu3 neuraminidase 3 involved_in IBA
ISO
ISS		 PMID:21873635
(MGI:3040535|PMID:14970224), (MGI:3765376|PMID:17708748), (MGI:6478528|PMID:11696012)
GO_REF:0000024
(PMID:10861246), (PMID:11298736), (PMID:15847605), (PMID:17334392)		 RGD
UniProt		 PMID:10861246 PMID:11298736 PMID:11696012 PMID:14970224 PMID:15847605 More... GO_REF:0000024 MGI:3040535 MGI:3765376 MGI:6478528, RGD:13792537 NCBI chr 1:154,137,732...154,148,879
Ensembl chr 1:154,050,855...154,148,813 		JBrowse link
G Neu4 neuraminidase 4 involved_in IBA
ISO		 PMID:21873635
(MGI:4361102|PMID:19506080)
(PMID:15213228), (PMID:15847605)		 RGD PMID:15213228 PMID:15847605 PMID:19506080 PMID:21873635 MGI:4361102, RGD:13792537 NCBI chr 9:94,396,920...94,402,576
Ensembl chr 9:94,396,920...94,402,576 		JBrowse link
ganglioside metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3718765|PMID:17488728)		 UniProt
RGD		 PMID:17488728 GO_REF:0000024 MGI:3718765 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537 		JBrowse link
G Cln6 CLN6, transmembrane ER protein involved_in ISO (PMID:16857350) RGD PMID:16857350 NCBI chr 8:63,303,356...63,318,360
Ensembl chr 8:63,303,029...63,318,360 		JBrowse link
G Gm2a ganglioside GM2 activator IDA RGD PMID:9770472 RGD:1598995 NCBI chr10:39,219,221...39,231,756
Ensembl chr10:39,219,243...39,231,757 		JBrowse link
G Itgb8 integrin subunit beta 8 acts_upstream_of_or_within ISO MGI:2180548 (MGI:3607039|PMID:16251442) RGD PMID:16251442 MGI:3607039 NCBI chr 6:140,125,002...140,208,261
Ensembl chr 6:140,127,203...140,208,476 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO MGI:1934018 (MGI:4950812|PMID:21408219) RGD PMID:21408219 MGI:4950812 NCBI chr10:86,001,545...86,009,049
Ensembl chr10:86,001,566...86,008,972 		JBrowse link
globoside biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A4galt alpha 1,4-galactosyltransferase (P blood group) acts_upstream_of_or_within ISO MGI:3624807|MGI:5445373 (MGI:3623723|PMID:16476743), (MGI:5445364|PMID:22875802) RGD PMID:16476743 PMID:22875802 MGI:3623723 MGI:5445364 NCBI chr 7:114,368,525...114,392,872
Ensembl chr 7:114,368,276...114,396,071 		JBrowse link
globoside biosynthetic process via lactosylceramide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G St3gal2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 involved_in ISO
IEA
ISS		 (PMID:12716912)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:12716912 GO_REF:0000024 GO_REF:0000107 NCBI chr19:38,888,851...38,939,874
Ensembl chr19:38,923,999...38,939,869 		JBrowse link
globoside metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gbgt1 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group) involved_in ISO (PMID:8855242) RGD PMID:8855242 NCBI chr 3:11,826,131...11,829,745 JBrowse link
glucosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fa2h fatty acid 2-hydroxylase involved_in ISS
ISO		 GO_REF:0000024
(MGI:5285470|PMID:21628453)		 UniProt
RGD		 PMID:21628453 GO_REF:0000024 MGI:5285470 NCBI chr19:39,312,904...39,364,153
Ensembl chr19:39,312,906...39,364,153 		JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase involved_in IBA
ISO
ISS		 PMID:21873635
(MGI:2180222|PMID:10430909), (MGI:3603060|PMID:16109770), (MGI:5448789|PMID:22851168), (MGI:5510915|PMID:23748427)
GO_REF:0000024
(PMID:8643456)		 RGD
UniProt		 PMID:8643456 PMID:10430909 PMID:16109770 PMID:22851168 PMID:23748427 More... GO_REF:0000024 MGI:2180222 MGI:3603060 MGI:5448789 MGI:5510915, RGD:13792537 NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393 		JBrowse link
glucosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gba1 glucosylceramidase beta 1 involved_in ISO
IBA		 (PMID:16293621), (PMID:19279011), (PMID:21700325), (PMID:24022302), (PMID:24211208), (PMID:9201993)
PMID:21873635
(MGI:5141165|PMID:21700325), (MGI:5501380|PMID:23707074), (MGI:6271235|PMID:24211208)		 RGD PMID:9201993 PMID:16293621 PMID:19279011 PMID:21700325 PMID:23707074 More... MGI:5141165 MGI:5501380 MGI:6271235, RGD:13792537 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263 		JBrowse link
G Gba2 glucosylceramidase beta 2 involved_in ISO
IEA
ISS		 (PMID:17080196), (PMID:30308956)
GO_REF:0000107
(MGI:3690511|PMID:17080196), (MGI:5484792|PMID:23250757)
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:17080196 PMID:23250757 PMID:30308956 GO_REF:0000024 GO_REF:0000107 MGI:3690511 MGI:5484792 NCBI chr 5:57,822,389...57,834,522
Ensembl chr 5:57,822,389...57,834,072 		JBrowse link
G Gba3 glucosylceramidase beta 3 involved_in
NOT|involved_in		 ISO (PMID:17595169), (PMID:26724485)
(PMID:20728381)		 RGD PMID:17595169 PMID:20728381 PMID:26724485 NCBI chr14:60,574,974...60,721,411
Ensembl chr14:60,574,976...60,721,653 		JBrowse link
glucosylceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gba1 glucosylceramidase beta 1 acts_upstream_of_or_within ISO (MGI:3762988|PMID:17954912), (MGI:3795074|PMID:18346921) RGD PMID:17954912 PMID:18346921 MGI:3762988 MGI:3795074 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263 		JBrowse link
G Psap prosaposin acts_upstream_of_or_within ISO (MGI:3711591|PMID:17353235) RGD PMID:17353235 MGI:3711591 NCBI chr20:28,214,229...28,240,501
Ensembl chr20:28,214,271...28,240,498 		JBrowse link
glycosphingolipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A3galt2 alpha 1,3-galactosyltransferase 2 acts_upstream_of_or_within
involved_in		 IDA
ISO		 PMID:10854427
MGI:1347344|MGI:3512453 (MGI:5445364|PMID:22875802)
PMID:12626403		 RGD PMID:22875802 PMID:10854427 PMID:10854427 PMID:12626403 MGI:5445364, RGD:1299594, RGD:1299594, RGD:632674 NCBI chr 5:141,101,329...141,113,760
Ensembl chr 5:141,107,983...141,115,641 		JBrowse link
G B4galnt1 beta-1,4-N-acetyl-galactosaminyl transferase 1 involved_in IDA PMID:1606358 UniProt PMID:1606358 RGD:21201272 NCBI chr 7:62,988,429...62,996,190
Ensembl chr 7:62,988,930...62,996,190 		JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:9593693 PMID:21873635 RGD:70807, RGD:13792537 NCBI chr18:11,958,382...12,015,247
Ensembl chr18:11,958,390...12,015,247 		JBrowse link
G Fut4 fucosyltransferase 4 involved_in ISO
ISS		 (PMID:29593094)
GO_REF:0000024		 RGD
UniProt		 PMID:29593094 GO_REF:0000024 NCBI chr 8:11,586,721...11,590,682
Ensembl chr 8:11,586,721...11,590,682 		JBrowse link
G Fut4-ps1 fucosyltransferase 4, pseudogene 1 involved_in ISO (PMID:29593094) RGD PMID:29593094 NCBI chr 9:1,569,605...1,572,022 JBrowse link
G Fut9 fucosyltransferase 9 involved_in ISO
ISS		 (PMID:29593094)
GO_REF:0000024		 RGD
UniProt		 PMID:29593094 GO_REF:0000024 NCBI chr 5:39,351,815...39,565,256
Ensembl chr 5:39,351,819...39,565,130 		JBrowse link
G St6galnac5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 involved_in ISO (MGI:1346847|PMID:10521438) RGD PMID:10521438 MGI:1346847 NCBI chr 2:241,741,933...241,911,214
Ensembl chr 2:241,742,688...241,911,208 		JBrowse link
G St8sia5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 involved_in IDA PMID:1606358 UniProt PMID:1606358 RGD:21201272 NCBI chr18:70,736,395...70,802,537
Ensembl chr18:70,736,602...70,797,789 		JBrowse link
G Tm9sf2 transmembrane 9 superfamily member 2 involved_in ISO (PMID:30660999) RGD PMID:30660999 NCBI chr15:99,201,556...99,254,054
Ensembl chr15:99,201,489...99,254,049 		JBrowse link
G Ugt8 UDP glycosyltransferase 8 TAS RGD PMID:7521399 RGD:70050 NCBI chr 2:214,264,483...214,332,769
Ensembl chr 2:214,264,483...214,332,660 		JBrowse link
glycosphingolipid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gla galactosidase, alpha involved_in ISO (PMID:10838196), (PMID:8804427) RGD PMID:8804427 PMID:10838196 NCBI chr  X:97,769,227...97,780,646
Ensembl chr  X:97,768,996...97,780,664 		JBrowse link
glycosphingolipid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3718765|PMID:17488728)		 UniProt
RGD		 PMID:17488728 GO_REF:0000024 MGI:3718765 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537 		JBrowse link
G B4galnt1 beta-1,4-N-acetyl-galactosaminyl transferase 1 involved_in
acts_upstream_of_or_within		 IDA
ISO		 PMID:3140234
MGI:2158349 (MGI:3797995|PMID:18308723)		 RGD PMID:18308723 PMID:3140234 MGI:3797995, RGD:21201261 NCBI chr 7:62,988,429...62,996,190
Ensembl chr 7:62,988,930...62,996,190 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within ISO MGI:1857429 (MGI:3797995|PMID:18308723) RGD PMID:18308723 MGI:3797995 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Crem cAMP responsive element modulator acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:2158921 (MGI:3797995|PMID:18308723)
GO_REF:0000107		 RGD
Ensembl		 PMID:18308723 GO_REF:0000107 MGI:3797995 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989 		JBrowse link
G Hexb hexosaminidase subunit beta acts_upstream_of_or_within ISO MGI:2429701 (MGI:78473|PMID:8789434) RGD PMID:8789434 MGI:78473 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:1856232 (MGI:3797995|PMID:18308723) RGD PMID:18308723 MGI:3797995 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Map7 microtubule-associated protein 7 acts_upstream_of_or_within ISO MGI:1889849 (MGI:3797995|PMID:18308723) RGD PMID:18308723 MGI:3797995 NCBI chr 1:14,910,433...15,037,574
Ensembl chr 1:14,910,551...15,037,574 		JBrowse link
G St6galnac3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 involved_in ISO (PMID:17123352) RGD PMID:17123352 NCBI chr 2:242,129,755...242,645,120
Ensembl chr 2:242,129,763...242,645,133 		JBrowse link
G St6galnac6 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 involved_in ISO (PMID:17123352) RGD PMID:17123352 NCBI chr 3:15,894,275...15,907,502
Ensembl chr 3:15,885,968...15,907,496 		JBrowse link
glycosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gba3 glucosylceramidase beta 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:60,574,974...60,721,411
Ensembl chr14:60,574,976...60,721,653 		JBrowse link
G Gla galactosidase, alpha acts_upstream_of_or_within ISO MGI:1861794 (MGI:1859538|PMID:10841515), (MGI:1860035|PMID:10840053), (MGI:2155538|PMID:11752062), (MGI:3525994|PMID:15629890), (MGI:86774|PMID:9122231) RGD PMID:9122231 PMID:10840053 PMID:10841515 PMID:11752062 PMID:15629890 MGI:1859538 MGI:1860035 MGI:2155538 MGI:3525994 MGI:86774 NCBI chr  X:97,769,227...97,780,646
Ensembl chr  X:97,768,996...97,780,664 		JBrowse link
G Lct lactase involved_in IDA PMID:4752949 UniProt PMID:4752949 RGD:151356630 NCBI chr13:39,781,929...39,824,456
Ensembl chr13:39,781,929...39,824,456 		JBrowse link
glycosylceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G St6galnac3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 involved_in ISO
IEA		 (PMID:17123352)
GO_REF:0000107		 RGD
Ensembl		 PMID:17123352 GO_REF:0000107 NCBI chr 2:242,129,755...242,645,120
Ensembl chr 2:242,129,763...242,645,133 		JBrowse link
G St6galnac6 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 involved_in ISO (PMID:17123352) RGD PMID:17123352 NCBI chr 3:15,894,275...15,907,502
Ensembl chr 3:15,885,968...15,907,496 		JBrowse link
lactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4galt4 beta-1,4-galactosyltransferase 4 involved_in ISO
ISS		 (PMID:9792633)
GO_REF:0000024		 RGD
UniProt		 PMID:9792633 GO_REF:0000024 NCBI chr11:61,995,807...62,021,751
Ensembl chr11:61,995,814...62,021,671 		JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 involved_in ISO (PMID:10320813) RGD PMID:10320813 NCBI chr18:11,958,382...12,015,247
Ensembl chr18:11,958,390...12,015,247 		JBrowse link
negative regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 acts_upstream_of_or_within ISO (PMID:25691431) RGD PMID:25691431 NCBI chr 9:48,243,365...48,253,316
Ensembl chr 9:48,237,572...48,253,211 		JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 acts_upstream_of_or_within ISO (PMID:25691431) RGD PMID:25691431 NCBI chr 7:1,247,869...1,250,999
Ensembl chr 7:1,246,479...1,250,907 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:25691431)
(MGI:5638294|PMID:25691431)		 Ensembl
RGD		 PMID:25691431 GO_REF:0000107 MGI:5638294 NCBI chr10:83,590,052...83,596,035
Ensembl chr10:83,590,071...83,598,620 		JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:6294167|PMID:16118219)
(PMID:16118219)		 UniProt
Ensembl
RGD		 PMID:16118219 GO_REF:0000024 GO_REF:0000107 MGI:6294167 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240 		JBrowse link
negative regulation of sphingolipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 involved_in ISO
IEA
IMP		 (PMID:24201375)
GO_REF:0000107		 RGD
Ensembl		 PMID:24201375 PMID:24201375 GO_REF:0000107, RGD:14697729 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537 		JBrowse link
G Atg7 autophagy related 7 acts_upstream_of_or_within ISO MGI:2176073|MGI:3587769 (MGI:5613260|PMID:25332431) RGD PMID:25332431 MGI:5613260 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
omega-hydroxyceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pnpla1 patatin-like phospholipase domain containing 1 involved_in ISO (PMID:28248318)
(MGI:5888934|PMID:28248300)		 RGD PMID:28248300 PMID:28248318 MGI:5888934 NCBI chr20:6,917,993...6,952,157
Ensembl chr20:6,917,931...6,952,375 		JBrowse link
phytosphingosine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acer3 alkaline ceramidase 3 involved_in IBA
ISO		 PMID:21873635
(PMID:11356846), (PMID:20068046)		 RGD PMID:11356846 PMID:20068046 PMID:21873635 RGD:13792537 NCBI chr 1:152,504,180...152,606,596
Ensembl chr 1:152,504,186...152,606,591 		JBrowse link
positive regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn1 cellular communication network factor 1 acts_upstream_of_or_within ISO (MGI:3849354|PMID:19364818) RGD PMID:19364818 MGI:3849354 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4947032|PMID:21177474)		 UniProt
RGD		 PMID:21177474 GO_REF:0000024 MGI:4947032 NCBI chr10:104,242,169...104,247,185
Ensembl chr10:104,242,223...104,246,589 		JBrowse link
G Pla2g6 phospholipase A2 group VI involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:18936091 PMID:21873635 RGD:6482750, RGD:13792537 NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114 		JBrowse link
G Prkcd protein kinase C, delta involved_in ISO
IEA		 (PMID:19279011)
GO_REF:0000107		 RGD
Ensembl		 PMID:19279011 GO_REF:0000107 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Sirt3 sirtuin 3 involved_in ISO (MGI:5755322|PMID:26620563) RGD PMID:26620563 MGI:5755322 NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 IMP RGD PMID:20096352 RGD:10041064 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749 		JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO (PMID:16118219)
(MGI:6294167|PMID:16118219)		 RGD PMID:16118219 MGI:6294167 NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391 		JBrowse link
positive regulation of glucosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkcd protein kinase C, delta involved_in ISO
IEA		 (PMID:19279011)
GO_REF:0000107		 RGD
Ensembl		 PMID:19279011 GO_REF:0000107 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
positive regulation of sphingomyelin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4947032|PMID:21177474)		 UniProt
RGD		 PMID:21177474 GO_REF:0000024 MGI:4947032 NCBI chr10:104,242,169...104,247,185
Ensembl chr10:104,242,223...104,246,589 		JBrowse link
G Prkcd protein kinase C, delta involved_in ISO
IEA		 (PMID:19279011)
GO_REF:0000107		 RGD
Ensembl		 PMID:19279011 GO_REF:0000107 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENSRNOG00000068509 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 Ensembl chr17:11,942,344...11,942,538 JBrowse link
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 acts_upstream_of ISO MGI:1913862 (MGI:6393026|PMID:31880535) RGD PMID:31880535 MGI:6393026 NCBI chr 9:48,243,365...48,253,316
Ensembl chr 9:48,237,572...48,253,211 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 acts_upstream_of ISO MGI:2137691|MGI:2181669|MGI:6382064 (MGI:6393026|PMID:31880535) RGD PMID:31880535 MGI:6393026 NCBI chr10:83,590,052...83,596,035
Ensembl chr10:83,590,071...83,598,620 		JBrowse link
G Prkcd protein kinase C, delta involved_in ISO
ISS		 (PMID:17303575)
GO_REF:0000024		 RGD
UniProt		 PMID:17303575 GO_REF:0000024 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Samd8 sterile alpha motif domain containing 8 involved_in ISO (PMID:19506037) RGD PMID:19506037 NCBI chr15:2,512,104...2,562,368
Ensembl chr15:2,512,105...2,515,379
Ensembl chr15:2,512,105...2,515,379 		JBrowse link
regulation of sphingolipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 acts_upstream_of ISO MGI:1913862 (MGI:6393026|PMID:31880535) RGD PMID:31880535 MGI:6393026 NCBI chr 9:48,243,365...48,253,316
Ensembl chr 9:48,237,572...48,253,211 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 acts_upstream_of ISO MGI:2137691|MGI:2181669|MGI:2445707|MGI:6343506|MGI:6382064 (MGI:5926671|PMID:28275141), (MGI:6393026|PMID:31880535) RGD PMID:28275141 PMID:31880535 MGI:5926671 MGI:6393026 NCBI chr10:83,590,052...83,596,035
Ensembl chr10:83,590,071...83,598,620 		JBrowse link
sphinganine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 acts_upstream_of_or_within ISO MGI:3815115 (MGI:3846467|PMID:19416652) RGD PMID:19416652 MGI:3846467 NCBI chr17:11,877,249...11,916,295
Ensembl chr17:11,877,249...11,916,295 		JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1098386|PMID:9363775)
GO_REF:0000107		 RGD
Ensembl		 PMID:9363775 GO_REF:0000107 MGI:1098386 NCBI chr 6:106,948,682...107,031,532
Ensembl chr 6:106,950,949...107,031,542 		JBrowse link
sphinganine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Degs2 delta(4)-desaturase, sphingolipid 2 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
SGD:S000002705 (MGI:3505861|PMID:11937514)
(MGI:3694278|PMID:16571104)		 RGD PMID:11937514 PMID:16571104 PMID:21873635 MGI:3505861 MGI:3694278, RGD:13792537 NCBI chr 6:127,596,063...127,613,293
Ensembl chr 6:127,596,071...127,613,293 		JBrowse link
sphinganine-1-phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sphk2 sphingosine kinase 2 involved_in ISO
IBA		 (PMID:10751414), (PMID:19729656)
PMID:21873635
(MGI:1860308|PMID:10751414)		 RGD PMID:10751414 PMID:19729656 PMID:21873635 MGI:1860308, RGD:13792537 NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391 		JBrowse link
sphinganine-1-phosphate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sgpp1 sphingosine-1-phosphate phosphatase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1932564|PMID:10859351), (MGI:2176350|PMID:11756451)
GO_REF:0000107		 RGD
Ensembl		 PMID:10859351 PMID:11756451 GO_REF:0000107 MGI:1932564 MGI:2176350 NCBI chr 6:94,425,339...94,446,534
Ensembl chr 6:94,425,339...94,446,534 		JBrowse link
sphingoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sptlc3 serine palmitoyltransferase, long chain base subunit 3 acts_upstream_of_or_within ISO (PMID:19648650) RGD PMID:19648650 NCBI chr 3:126,847,878...126,978,010
Ensembl chr 3:126,847,878...126,978,010 		JBrowse link
sphingolipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acer1 alkaline ceramidase 1 involved_in ISO (PMID:17713573) RGD PMID:17713573 NCBI chr 9:1,794,340...1,824,432
Ensembl chr 9:1,793,139...1,824,434 		JBrowse link
G Atg7 autophagy related 7 acts_upstream_of ISO MGI:2176073|MGI:3587769 (MGI:5613260|PMID:25332431) RGD PMID:25332431 MGI:5613260 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
G Cerkl ceramide kinase-like acts_upstream_of_or_within ISO MGI:5461515 (MGI:5571022|PMID:23501591) RGD PMID:23501591 MGI:5571022 NCBI chr 3:64,238,714...64,344,695
Ensembl chr 3:64,237,522...64,340,675 		JBrowse link
G Cers1 ceramide synthase 1 involved_in ISO (PMID:12105227) RGD PMID:12105227 NCBI chr16:19,097,309...19,112,519
Ensembl chr16:19,104,466...19,112,519 		JBrowse link
G Cers2 ceramide synthase 2 acts_upstream_of_or_within ISO (MGI:3696894|PMID:15823095) RGD PMID:15823095 MGI:3696894 NCBI chr 2:182,890,527...182,898,805
Ensembl chr 2:182,890,493...182,933,314 		JBrowse link
G Cers3 ceramide synthase 3 acts_upstream_of_or_within ISO (MGI:3692343|PMID:16753040) RGD PMID:16753040 MGI:3692343 NCBI chr 1:120,316,930...120,422,926
Ensembl chr 1:120,318,212...120,422,902 		JBrowse link
G Cers4 ceramide synthase 4 acts_upstream_of_or_within ISO (MGI:3696894|PMID:15823095) RGD PMID:15823095 MGI:3696894 NCBI chr12:2,851,784...2,890,244
Ensembl chr12:2,851,784...2,886,828 		JBrowse link
G Cers5 ceramide synthase 5 acts_upstream_of_or_within ISO (MGI:3696894|PMID:15823095) RGD PMID:15823095 MGI:3696894 NCBI chr 7:130,859,993...130,897,979
Ensembl chr 7:130,859,990...130,897,947 		JBrowse link
G Cers6 ceramide synthase 6 acts_upstream_of_or_within ISO (MGI:3696894|PMID:15823095) RGD PMID:15823095 MGI:3696894 NCBI chr 3:53,630,637...53,879,692
Ensembl chr 3:53,630,959...53,876,848 		JBrowse link
G Degs2 delta(4)-desaturase, sphingolipid 2 acts_upstream_of_or_within ISO SGD:S000002705 (MGI:3505861|PMID:11937514) RGD PMID:11937514 MGI:3505861 NCBI chr 6:127,596,063...127,613,293
Ensembl chr 6:127,596,071...127,613,293 		JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 involved_in ISO
IBA		 (PMID:20937905)
PMID:21873635
(MGI:4944052|PMID:20253178)		 RGD PMID:20253178 PMID:20937905 PMID:21873635 MGI:4944052, RGD:13792537 NCBI chr 5:131,961,478...131,965,961
Ensembl chr 5:131,961,322...131,965,958 		JBrowse link
G Elovl2 ELOVL fatty acid elongase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:23,544,598...23,584,855
Ensembl chr17:23,544,568...23,584,848 		JBrowse link
G Elovl3 ELOVL fatty acid elongase 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:244,997,287...245,001,115
Ensembl chr 1:244,997,287...245,001,115 		JBrowse link
G Elovl4 ELOVL fatty acid elongase 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:84,702,916...84,729,466
Ensembl chr 8:84,702,362...84,729,697 		JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:78,790,846...78,857,307
Ensembl chr 8:78,790,846...78,857,284 		JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186 		JBrowse link
G Elovl7 ELOVL fatty acid elongase 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:39,789,229...39,858,579
Ensembl chr 2:39,789,250...39,856,845 		JBrowse link
G Hacd1 3-hydroxyacyl-CoA dehydratase 1 involved_in ISO
IBA		 UniProtKB:P40857 (PMID:18554506)
PMID:21873635		 RGD PMID:18554506 PMID:21873635 RGD:13792537 NCBI chr17:77,081,508...77,106,114
Ensembl chr17:77,083,740...77,106,073 		JBrowse link
G Hacd2 3-hydroxyacyl-CoA dehydratase 2 involved_in ISO
IBA		 UniProtKB:P40857 (PMID:18554506)
PMID:21873635		 RGD PMID:18554506 PMID:21873635 RGD:13792537 NCBI chr11:65,667,671...65,762,903
Ensembl chr11:65,670,281...65,762,889 		JBrowse link
G Hacd3 3-hydroxyacyl-CoA dehydratase 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:65,501,240...65,538,507
Ensembl chr 8:65,501,240...65,538,507 		JBrowse link
G Hacd4 3-hydroxyacyl-CoA dehydratase 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:102,887,597...102,915,376
Ensembl chr 5:102,887,588...102,915,338 		JBrowse link
G Kdsr 3-ketodihydrosphingosine reductase acts_upstream_of_or_within
involved_in		 ISO
IBA		 SGD:S000000469 (MGI:3522414|PMID:15328338)
PMID:21873635		 RGD PMID:15328338 PMID:21873635 MGI:3522414, RGD:13792537 NCBI chr13:22,862,117...22,894,118
Ensembl chr13:22,862,117...22,894,108 		JBrowse link
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:48,243,365...48,253,316
Ensembl chr 9:48,237,572...48,253,211 		JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:1,247,869...1,250,999
Ensembl chr 7:1,246,479...1,250,907 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:83,590,052...83,596,035
Ensembl chr10:83,590,071...83,598,620 		JBrowse link
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 acts_upstream_of_or_within ISO (PMID:25332431) RGD PMID:25332431 NCBI chr17:11,877,249...11,916,295
Ensembl chr17:11,877,249...11,916,295 		JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:25332431)
(PMID:26573920)
(MGI:5917779|PMID:28698261)		 UniProt
RGD		 PMID:25332431 PMID:26573920 PMID:28698261 GO_REF:0000024 MGI:5917779 NCBI chr 6:106,948,682...107,031,532
Ensembl chr 6:106,950,949...107,031,542 		JBrowse link
G Sptssb serine palmitoyltransferase, small subunit B acts_upstream_of_or_within ISO MGI:5689843 (MGI:5689923|PMID:26438849) RGD PMID:26438849 MGI:5689923 NCBI chr 2:154,133,728...154,162,127
Ensembl chr 2:154,133,733...154,163,120 		JBrowse link
sphingolipid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:14500380)		 UniProt
Ensembl
RGD		 PMID:14500380 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827 		JBrowse link
G Sgpl1 sphingosine-1-phosphate lyase 1 involved_in ISS
IEA
IBA
ISO		 GO_REF:0000024
GO_REF:0000107
PMID:21873635
(PMID:24809814), (PMID:28165339)		 UniProt
Ensembl
RGD		 PMID:24809814 PMID:28165339 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr20:29,047,793...29,094,209
Ensembl chr20:29,047,796...29,094,084 		JBrowse link
G Smpd2 sphingomyelin phosphodiesterase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:44,986,229...44,989,343
Ensembl chr20:44,986,231...44,989,441 		JBrowse link
G Vps54 VPS54 subunit of GARP complex involved_in ISO
IEA		 MGI:1857091 (MGI:6430941|PMID:32345721)
GO_REF:0000107		 RGD
Ensembl		 PMID:32345721 GO_REF:0000107 MGI:6430941 NCBI chr14:95,378,821...95,455,871
Ensembl chr14:95,378,012...95,455,857 		JBrowse link
sphingomyelin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca8 ATP binding cassette subfamily A member 8 involved_in ISO (PMID:23560799) RGD PMID:23560799 NCBI chr10:94,917,520...94,991,199
Ensembl chr10:94,917,520...94,990,988 		JBrowse link
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 acts_upstream_of ISO MGI:1913862 (MGI:6393026|PMID:31880535) RGD PMID:31880535 MGI:6393026 NCBI chr 9:48,243,365...48,253,316
Ensembl chr 9:48,237,572...48,253,211 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 acts_upstream_of
involved_in		 ISO
IEA		 MGI:2137691|MGI:2181669|MGI:6382064 (MGI:6393026|PMID:31880535)
GO_REF:0000107		 RGD
Ensembl		 PMID:31880535 GO_REF:0000107 MGI:6393026 NCBI chr10:83,590,052...83,596,035
Ensembl chr10:83,590,071...83,598,620 		JBrowse link
G Osbp oxysterol binding protein involved_in ISO (PMID:12023275) RGD PMID:12023275 NCBI chr 1:208,888,697...208,918,511
Ensembl chr 1:208,887,895...208,918,506 		JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase acts_upstream_of_or_within ISO (MGI:5707904|PMID:25667419) RGD PMID:25667419 MGI:5707904 NCBI chr10:44,775,910...44,849,990
Ensembl chr10:44,775,911...44,850,013 		JBrowse link
G Sgms1 sphingomyelin synthase 1 involved_in IBA
ISO
ISS		 PMID:21873635
(MGI:6221394|PMID:27892528)
GO_REF:0000024
(PMID:14685263), (PMID:14976195), (PMID:17982138)		 RGD
HGNC-UCL		 PMID:14685263 PMID:14976195 PMID:17982138 PMID:27892528 PMID:21873635 GO_REF:0000024 MGI:6221394, RGD:13792537 NCBI chr 1:229,996,673...230,259,591
Ensembl chr 1:229,998,119...230,259,603 		JBrowse link
G Sgms2 sphingomyelin synthase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
(MGI:6221394|PMID:27892528)
(MGI:5707904|PMID:25667419)
(PMID:14685263), (PMID:17982138)
PMID:21873635		 Ensembl
RGD		 PMID:14685263 PMID:17982138 PMID:25667419 PMID:27892528 PMID:21873635 GO_REF:0000107 MGI:5707904 MGI:6221394, RGD:13792537 NCBI chr 2:219,889,809...219,967,704
Ensembl chr 2:219,893,572...219,967,546 		JBrowse link
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 involved_in
acts_upstream_of_or_within		 ISO (MGI:5749304|PMID:26301690)
MGI:3815115 (MGI:3814228|PMID:16216550)		 RGD PMID:16216550 PMID:26301690 MGI:3814228 MGI:5749304 NCBI chr17:11,877,249...11,916,295
Ensembl chr17:11,877,249...11,916,295 		JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:3815117 (MGI:3814228|PMID:16216550)
GO_REF:0000107		 RGD
Ensembl		 PMID:16216550 GO_REF:0000107 MGI:3814228 NCBI chr 6:106,948,682...107,031,532
Ensembl chr 6:106,950,949...107,031,542 		JBrowse link
G Vapa VAMP associated protein A involved_in ISO (PMID:12023275) RGD PMID:12023275 NCBI chr 9:105,177,904...105,208,400
Ensembl chr 9:105,177,907...105,207,847 		JBrowse link
sphingomyelin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smpd1 sphingomyelin phosphodiesterase 1 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:18815062), (PMID:20807762), (PMID:22573858)
PMID:21873635
(MGI:5529577|PMID:23973266)		 RGD PMID:18815062 PMID:20807762 PMID:22573858 PMID:23973266 PMID:21873635 MGI:5529577, RGD:13792537 NCBI chr 1:159,892,946...159,896,789
Ensembl chr 1:159,892,859...159,896,794 		JBrowse link
G Smpd2 sphingomyelin phosphodiesterase 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5529577|PMID:23973266)
GO_REF:0000107
(MGI:1202145|PMID:9520418)
(PMID:10608884), (PMID:14741383)		 RGD
Ensembl		 PMID:9520418 PMID:10608884 PMID:14741383 PMID:23973266 GO_REF:0000107 MGI:1202145 MGI:5529577 NCBI chr20:44,986,229...44,989,343
Ensembl chr20:44,986,231...44,989,441 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:14741383)
(MGI:5529577|PMID:23973266)		 Ensembl
RGD		 PMID:14741383 PMID:23973266 GO_REF:0000107 MGI:5529577 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749 		JBrowse link
G Smpd4 sphingomyelin phosphodiesterase 4 involved_in ISO
IBA		 (PMID:16517606), (PMID:25180167)
PMID:21873635
(MGI:6450503|PMID:25180167)		 RGD PMID:16517606 PMID:25180167 PMID:21873635 MGI:6450503, RGD:13792537 NCBI chr11:83,362,534...83,386,257
Ensembl chr11:83,362,534...83,386,250 		JBrowse link
G Smpd5 sphingomyelin phosphodiesterase 5 involved_in ISO (MGI:6450238|PMID:21183079) RGD PMID:21183079 MGI:6450238 NCBI chr 7:108,009,182...108,011,767
Ensembl chr 7:108,009,173...108,011,763 		JBrowse link
G Smpdl3a sphingomyelin phosphodiesterase, acid-like 3A NOT|involved_in ISO
ISS		 (PMID:26783088)
GO_REF:0000024		 RGD
UniProt		 PMID:26783088 GO_REF:0000024 NCBI chr20:37,132,592...37,155,567
Ensembl chr20:37,132,592...37,155,567 		JBrowse link
G Smpdl3b sphingomyelin phosphodiesterase, acid-like 3B involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:144,944,618...144,966,703
Ensembl chr 5:144,944,636...144,966,720 		JBrowse link
sphingomyelin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3718765|PMID:17488728)		 UniProt
RGD		 PMID:17488728 GO_REF:0000024 MGI:3718765 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537 		JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12671034), (PMID:12885774), (PMID:28292932)		 UniProt
RGD		 PMID:12671034 PMID:12885774 PMID:28292932 GO_REF:0000024 NCBI chr10:104,242,169...104,247,185
Ensembl chr10:104,242,223...104,246,589 		JBrowse link
G Smpd2 sphingomyelin phosphodiesterase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:44,986,229...44,989,343
Ensembl chr20:44,986,231...44,989,441 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within		 ISS
IBA
ISO		 GO_REF:0000024
PMID:21873635
(MGI:1858672|PMID:10823942)
(MGI:6450311|PMID:21550973)		 UniProt
RGD		 PMID:10823942 PMID:21550973 PMID:21873635 GO_REF:0000024 MGI:1858672 MGI:6450311, RGD:13792537 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749 		JBrowse link
G Smpd5 sphingomyelin phosphodiesterase 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:108,009,182...108,011,767
Ensembl chr 7:108,009,173...108,011,763 		JBrowse link
sphingosine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of_positive_effect
involved_in		 ISO
IEA		 (PMID:26510981)
GO_REF:0000107		 RGD
Ensembl		 PMID:26510981 GO_REF:0000107 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537 		JBrowse link
G Acer1 alkaline ceramidase 1 involved_in ISO
IBA		 (PMID:17713573), (PMID:20207939), (PMID:20628055)
PMID:21873635
(MGI:5800647|PMID:27126290), (MGI:6107252|PMID:29056331)		 RGD PMID:17713573 PMID:20207939 PMID:20628055 PMID:27126290 PMID:29056331 More... MGI:5800647 MGI:6107252, RGD:13792537 NCBI chr 9:1,794,340...1,824,432
Ensembl chr 9:1,793,139...1,824,434 		JBrowse link
G Acer2 alkaline ceramidase 2 involved_in ISO
IBA		 (PMID:16940153), (PMID:20089856), (PMID:20207939), (PMID:20628055)
PMID:21873635
(MGI:6116621|PMID:29401619)		 RGD PMID:16940153 PMID:20089856 PMID:20207939 PMID:20628055 PMID:29401619 More... MGI:6116621, RGD:13792537 NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614 		JBrowse link
G Acer3 alkaline ceramidase 3 involved_in ISO (PMID:20068046), (PMID:20207939), (PMID:26792856)
(MGI:5749603|PMID:26474409)		 RGD PMID:20068046 PMID:20207939 PMID:26474409 PMID:26792856 MGI:5749603 NCBI chr 1:152,504,180...152,606,596
Ensembl chr 1:152,504,186...152,606,591 		JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:1267186|PMID:9653654)
(PMID:10610716), (PMID:12815059)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:9653654 PMID:10610716 PMID:12815059 GO_REF:0000024 GO_REF:0000107 MGI:1267186 NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233 		JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in IDA
ISO
IBA		 PMID:10488143
PMID:15123644
(MGI:3608219|PMID:16126722), (MGI:3640407|PMID:16380386), (MGI:6275120|PMID:10652340)
PMID:15217782
PMID:21873635
(PMID:30154232)		 RGD PMID:10652340 PMID:16126722 PMID:16380386 PMID:30154232 PMID:10488143 More... MGI:3608219 MGI:3640407 MGI:6275120, RGD:13838800, RGD:13838793, RGD:13838794, RGD:13792537 NCBI chr 1:229,865,662...229,973,253
Ensembl chr 1:229,865,662...229,939,162 		JBrowse link
G ENSRNOG00000069695 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 Ensembl chr14:25,729,638...25,730,194 JBrowse link
G Gba1 glucosylceramidase beta 1 involved_in ISO (PMID:19279011) RGD PMID:19279011 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263 		JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISO
IEA
IBA		 UniProtKB:Q9NRA0 (PMID:23106337)
GO_REF:0000107
PMID:21873635		 RGD
Ensembl		 PMID:23106337 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240 		JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO
IBA		 UniProtKB:Q9NYA1 (PMID:23106337)
PMID:21873635		 RGD PMID:23106337 PMID:21873635 RGD:13792537 NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391 		JBrowse link
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:3815115 (MGI:3814228|PMID:16216550)
PMID:21873635
(PMID:19416851), (PMID:33558761)		 RGD PMID:16216550 PMID:19416851 PMID:33558761 PMID:21873635 MGI:3814228, RGD:13792537 NCBI chr17:11,877,249...11,916,295
Ensembl chr17:11,877,249...11,916,295 		JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 acts_upstream_of_or_within
involved_in		 ISO
IEA
IBA		 MGI:3815117 (MGI:3814228|PMID:16216550)
GO_REF:0000107
PMID:21873635
(PMID:19416851), (PMID:33558761)		 RGD
Ensembl		 PMID:16216550 PMID:19416851 PMID:33558761 PMID:21873635 GO_REF:0000107 MGI:3814228, RGD:13792537 NCBI chr 6:106,948,682...107,031,532
Ensembl chr 6:106,950,949...107,031,542 		JBrowse link
G Sptlc3 serine palmitoyltransferase, long chain base subunit 3 involved_in ISO
IBA		 (PMID:19416851)
PMID:21873635		 RGD PMID:19416851 PMID:21873635 RGD:13792537 NCBI chr 3:126,847,878...126,978,010
Ensembl chr 3:126,847,878...126,978,010 		JBrowse link
G Sptssa serine palmitoyltransferase, small subunit A involved_in ISO (PMID:19416851), (PMID:33558761) RGD PMID:19416851 PMID:33558761 NCBI chr 6:72,144,714...72,156,130
Ensembl chr 6:72,144,714...72,156,214 		JBrowse link
G Sptssb serine palmitoyltransferase, small subunit B involved_in ISO (PMID:19416851) RGD PMID:19416851 NCBI chr 2:154,133,728...154,162,127
Ensembl chr 2:154,133,733...154,163,120 		JBrowse link
sphingosine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in ISO
ISS		 (PMID:10781606), (PMID:15946935), (PMID:16229686), (PMID:17475390), (PMID:26190575)
GO_REF:0000024		 RGD
UniProt		 PMID:10781606 PMID:15946935 PMID:16229686 PMID:17475390 PMID:26190575 GO_REF:0000024 NCBI chr 1:229,865,662...229,973,253
Ensembl chr 1:229,865,662...229,939,162 		JBrowse link
G Naaa N-acylethanolamine acid amidase involved_in ISO
ISS		 (PMID:15655246)
GO_REF:0000024		 RGD
UniProt		 PMID:15655246 GO_REF:0000024 NCBI chr14:15,777,306...15,796,411
Ensembl chr14:15,777,306...15,796,410 		JBrowse link
G Plpp1 phospholipid phosphatase 1 involved_in IDA
IEA
ISO		 PMID:10359651
GO_REF:0000107
(MGI:6383560|PMID:10359651)
PMID:8663293
(PMID:9705349)		 Ensembl
RGD		 PMID:9705349 PMID:10359651 PMID:10359651 PMID:8663293 GO_REF:0000107 MGI:6383560, RGD:15090857, RGD:15090855 NCBI chr 2:44,439,002...44,500,430
Ensembl chr 2:44,438,994...44,501,268 		JBrowse link
G Plpp2 phospholipid phosphatase 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:9705349)		 UniProt
RGD		 PMID:9705349 GO_REF:0000024 NCBI chr 7:10,175,918...10,184,032
Ensembl chr 7:10,175,948...10,184,071 		JBrowse link
G Plpp3 phospholipid phosphatase 3 involved_in ISO
ISS		 (PMID:9305923), (PMID:9705349)
GO_REF:0000024		 RGD
UniProt		 PMID:9305923 PMID:9705349 GO_REF:0000024 NCBI chr 5:119,927,085...120,002,206
Ensembl chr 5:119,927,085...120,002,205 		JBrowse link
G Sgpp1 sphingosine-1-phosphate phosphatase 1 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 PMID:21873635
GO_REF:0000107
(MGI:2176350|PMID:11756451)		 Ensembl
RGD		 PMID:11756451 PMID:21873635 GO_REF:0000107 MGI:2176350, RGD:13792537 NCBI chr 6:94,425,339...94,446,534
Ensembl chr 6:94,425,339...94,446,534 		JBrowse link
G Sgpp2 sphingosine-1-phosphate phosphatase 2 involved_in ISO
IBA		 (PMID:12411432)
PMID:21873635		 RGD PMID:12411432 PMID:21873635 RGD:13792537 NCBI chr 9:79,762,658...79,884,665
Ensembl chr 9:79,763,284...79,880,457 		JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISO
ISS		 (PMID:20577214)
GO_REF:0000024		 RGD
UniProt		 PMID:20577214 GO_REF:0000024 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240 		JBrowse link
G Sphk2 sphingosine kinase 2 involved_in
acts_upstream_of_or_within		 ISO (MGI:3703830|PMID:17346996)
MGI:3580701 (MGI:3608224|PMID:16093248)		 RGD PMID:16093248 PMID:17346996 MGI:3608224 MGI:3703830 NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19574
    metabolic process 11556
      nitrogen compound metabolic process 9337
        organonitrogen compound metabolic process 5634
          sphingolipid metabolic process 151
            ceramide metabolic process + 106
            ceramide phosphoethanolamine metabolic process + 2
            glycosphingolipid metabolic process + 55
            inositol phosphoceramide metabolic process + 0
            sphinganine-1-phosphate metabolic process + 2
            sphingoid metabolic process + 23
            sphingolipid biosynthetic process + 100
            sphingolipid catabolic process + 32
            sphingomyelin metabolic process + 20
Path 2
Term Annotations click to browse term
  biological_process 19574
    metabolic process 11556
      primary metabolic process 9996
        lipid metabolic process 1406
          cellular lipid metabolic process 1035
            membrane lipid metabolic process 176
              sphingolipid metabolic process 151
                ceramide metabolic process + 106
                ceramide phosphoethanolamine metabolic process + 2
                glycosphingolipid metabolic process + 55
                inositol phosphoceramide metabolic process + 0
                sphinganine-1-phosphate metabolic process + 2
                sphingoid metabolic process + 23
                sphingolipid biosynthetic process + 100
                sphingolipid catabolic process + 32
                sphingomyelin metabolic process + 20
paths to the root