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ONTOLOGY REPORT - ANNOTATIONS


Term:sphingolipid metabolic process
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Accession:GO:0006665 term browser browse the term
Definition:The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
Synonyms:exact_synonym: sphingolipid metabolism


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sphingolipid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07028989.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr10:1,622,573...1,674,701 JBrowse link
G Acer1 alkaline ceramidase 1 ISO (MGI:MGI:2670497|PMID:12783875) RGD PMID:12783875 MGI:MGI:2670497 NCBI chr 9:10,061,978...10,093,588
Ensembl chr 9:10,061,978...10,093,588
JBrowse link
G Agk acylglycerol kinase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:68,483,345...68,561,518
Ensembl chr 4:68,483,320...68,560,801
JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type ISO
ISS
(PMID:21558561)
GO_REF:0000024
RGD
UniProt
PMID:21558561 GO_REF:0000024 NCBI chr10:55,744,646...55,756,524
Ensembl chr10:55,744,588...55,756,566
JBrowse link
G Aloxe3 arachidonate lipoxygenase 3 ISO
ISS
(PMID:21558561)
GO_REF:0000024
RGD
UniProt
PMID:21558561 GO_REF:0000024 NCBI chr10:55,711,996...55,735,915
Ensembl chr10:55,712,043...55,735,911
JBrowse link
G Arv1 ARV1 homolog, fatty acid homeostasis modulator IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:57,484,720...57,496,539
Ensembl chr19:57,484,634...57,496,695
JBrowse link
G Cerk ceramide kinase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:127,015,162...127,058,056
Ensembl chr 7:127,015,162...127,058,056
JBrowse link
G Cerkl ceramide kinase-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:66,268,835...66,395,615
Ensembl chr 3:66,268,947...66,394,764
JBrowse link
G Gal3st1 galactose-3-O-sulfotransferase 1 ISO (PMID:8830034) RGD PMID:8830034 NCBI chr14:84,231,473...84,247,371
Ensembl chr14:84,231,639...84,247,369
JBrowse link
G Pdxdc1 pyridoxal-dependent decarboxylase domain containing 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:3,232,794...3,321,438
Ensembl chr10:3,232,794...3,321,412
JBrowse link
G Psap prosaposin ISO MGI:MGI:2183897 (MGI:MGI:2183819|PMID:11371512) RGD PMID:11371512 MGI:MGI:2183819 NCBI chr20:29,831,302...29,856,876
Ensembl chr20:29,831,314...29,856,875
JBrowse link
G Psapl1 prosaposin-like 1 IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr14:79,711,694...79,714,254
Ensembl chr14:79,711,694...79,714,254
JBrowse link
G Serinc1 serine incorporator 1 IDA PMID:16120614 HGNC PMID:16120614 RGD:8553290 NCBI chr20:38,966,016...38,985,056
Ensembl chr20:38,967,238...38,985,036
JBrowse link
G Serinc2 serine incorporator 2 ISS PMID:16120614 HGNC PMID:16120614 RGD:8553290 NCBI chr 5:148,470,060...148,492,232
Ensembl chr 5:148,470,061...148,492,232
JBrowse link
G Serinc3 serine incorporator 3 ISS PMID:16120614 HGNC PMID:16120614 RGD:8553290 NCBI chr 3:160,018,643...160,038,078
Ensembl chr 3:160,018,646...160,038,078
JBrowse link
G Serinc5 serine incorporator 5 IEA
ISS
GO_REF:0000002
PMID:16120614
InterPro PMID:16120614 GO_REF:0000002, RGD:8553290 NCBI chr 2:22,195,507...22,310,289
Ensembl chr 2:22,195,600...22,310,312
JBrowse link
G Sftpb surfactant protein B IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:100,166,855...100,175,941
Ensembl chr 4:100,166,863...100,175,938
JBrowse link
G Sgms1 sphingomyelin synthase 1 IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:250,692,448...250,951,685
Ensembl chr 1:250,691,370...250,951,697
JBrowse link
G Sgpl1 sphingosine-1-phosphate lyase 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:30,699,936...30,769,178
Ensembl chr20:30,699,872...30,749,940
JBrowse link
G Sgpp1 sphingosine-1-phosphate phosphatase 1 ISO (MGI:MGI:1932564|PMID:10859351), (MGI:MGI:2386810|PMID:12235122) RGD PMID:10859351, PMID:12235122 MGI:MGI:1932564, MGI:MGI:2386810 NCBI chr 6:98,675,324...98,696,492
Ensembl chr 6:98,675,326...98,695,988
JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 ISO MGI:MGI:1856877 (MGI:MGI:5469952|PMID:22945695) RGD PMID:22945695 MGI:MGI:5469952 NCBI chr19:38,237,963...38,321,572
Ensembl chr19:38,237,965...38,321,528
JBrowse link
G Sphk1 sphingosine kinase 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:105,498,728...105,504,401
Ensembl chr10:105,498,728...105,504,393
JBrowse link
G Sphk2 sphingosine kinase 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:101,692,972...101,700,604
Ensembl chr 1:101,692,973...101,697,277
JBrowse link
G Spns2 sphingolipid transporter 2 ISO MGI:MGI:4460276 (MGI:MGI:5490425|PMID:23180825) RGD PMID:23180825 MGI:MGI:5490425 NCBI chr10:59,010,428...59,049,482
Ensembl chr10:59,010,428...59,049,482
JBrowse link
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 ISO (MGI:MGI:5896517|PMID:28100772) RGD PMID:28100772 MGI:MGI:5896517 NCBI chr17:11,856,525...11,895,566
Ensembl chr17:11,856,525...11,895,566
JBrowse link
G Tecr trans-2,3-enoyl-CoA reductase ISO
IEA
ISS
(PMID:25049234)
GO_REF:0000041
GO_REF:0000024
RGD
UniProt
PMID:25049234 GO_REF:0000024, GO_REF:0000041 NCBI chr19:24,705,478...24,732,024
Ensembl chr19:24,705,481...24,732,024
JBrowse link
G Th tyrosine hydroxylase IEP sphingosine 1-phosphate RGD PMID:21076868 RGD:5128811 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Zpbp2 zona pellucida binding protein 2 ISO MGI:MGI:3762590 (MGI:MGI:6150730|PMID:29536159) RGD PMID:29536159 MGI:MGI:6150730 NCBI chr10:86,513,645...86,523,375
Ensembl chr10:86,514,830...86,523,372
JBrowse link
3-keto-sphinganine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdsr 3-ketodihydrosphingosine reductase ISO
IBA
(PMID:15364918)
PMID:21873635
RGD PMID:15364918, PMID:21873635 RGD:13792537 NCBI chr13:26,779,386...26,812,271
Ensembl chr13:26,780,633...26,812,215
JBrowse link
ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agk acylglycerol kinase ISO
IBA
(MGI:MGI:3054595|PMID:15252046)
PMID:21873635
RGD PMID:15252046, PMID:21873635 MGI:MGI:3054595, RGD:13792537 NCBI chr 4:68,483,345...68,561,518
Ensembl chr 4:68,483,320...68,560,801
JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:3789553|PMID:17403930)
Ensembl
UniProt
RGD
PMID:17403930 GO_REF:0000024, GO_REF:0000107, MGI:MGI:3789553 NCBI chr10:55,744,646...55,756,524
Ensembl chr10:55,744,588...55,756,566
JBrowse link
G Aloxe3 arachidonate lipoxygenase 3 ISO
ISS
(MGI:MGI:5488571|PMID:22832496)
GO_REF:0000024
RGD
UniProt
PMID:22832496 GO_REF:0000024, MGI:MGI:5488571 NCBI chr10:55,711,996...55,735,915
Ensembl chr10:55,712,043...55,735,911
JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 IEA
ISO
ISS
GO_REF:0000107
(PMID:12764132), (PMID:12815059)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:12764132, PMID:12815059 GO_REF:0000024, GO_REF:0000107 NCBI chr16:53,998,604...54,030,006
Ensembl chr16:53,998,560...54,040,836
JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 IDA
ISO
PMID:11278489
(MGI:MGI:6274955|PMID:21613224)
(PMID:11278489), (PMID:17475390)
PMID:15123644
RGD PMID:11278489, PMID:17475390, PMID:21613224, PMID:11278489, PMID:15123644 MGI:MGI:6274955, RGD:13838803, RGD:13838793 NCBI chr 1:250,557,042...250,665,083
Ensembl chr 1:250,557,044...250,630,677
JBrowse link
G Cers1 ceramide synthase 1 ISO (PMID:12105227), (PMID:12869556), (PMID:15823095), (PMID:17548428), (PMID:18541923), (PMID:24782409)
(MGI:MGI:3696321|PMID:16951403), (MGI:MGI:3764760|PMID:17977534), (MGI:MGI:5755322|PMID:26620563)
RGD PMID:12105227, PMID:12869556, PMID:15823095, PMID:16951403, PMID:17548428, PMID:17977534, PMID:18541923, PMID:24782409, PMID:26620563 MGI:MGI:3696321, MGI:MGI:3764760, MGI:MGI:5755322 NCBI chr16:20,845,580...20,860,789
Ensembl chr16:20,845,576...20,860,789
JBrowse link
G Cers2 ceramide synthase 2 ISO
IBA
(PMID:17977534), (PMID:18165233), (PMID:29632068)
PMID:21873635
(MGI:MGI:3696894|PMID:15823095), (MGI:MGI:5755322|PMID:26620563)
RGD PMID:15823095, PMID:17977534, PMID:18165233, PMID:26620563, PMID:29632068, PMID:21873635 MGI:MGI:3696894, MGI:MGI:5755322, RGD:13792537 NCBI chr 2:196,487,656...196,495,930
Ensembl chr 2:196,487,656...196,496,986
JBrowse link
G Cers3 ceramide synthase 3 ISO
IBA
(PMID:17977534), (PMID:22038835), (PMID:23754960)
PMID:21873635
(MGI:MGI:5303015|PMID:22038835)
RGD PMID:17977534, PMID:22038835, PMID:23754960, PMID:21873635 MGI:MGI:5303015, RGD:13792537 NCBI chr 1:127,706,618...127,781,041
Ensembl chr 1:127,648,234...127,781,017
JBrowse link
G Cers4 ceramide synthase 4 ISO
IBA
(MGI:MGI:2679796|PMID:12912983), (MGI:MGI:3696894|PMID:15823095)
PMID:21873635
(PMID:17977534), (PMID:29632068)
RGD PMID:12912983, PMID:15823095, PMID:17977534, PMID:29632068, PMID:21873635 MGI:MGI:2679796, MGI:MGI:3696894, RGD:13792537 NCBI chr12:4,439,750...4,474,759
Ensembl chr12:4,439,750...4,474,729
JBrowse link
G Cers5 ceramide synthase 5 ISO
IBA
(PMID:16951403), (PMID:29632068)
PMID:21873635
(MGI:MGI:3696624|PMID:16100120), (MGI:MGI:3722529|PMID:17609214), (MGI:MGI:3764760|PMID:17977534)
RGD PMID:16100120, PMID:16951403, PMID:17609214, PMID:17977534, PMID:29632068, PMID:21873635 MGI:MGI:3696624, MGI:MGI:3722529, MGI:MGI:3764760, RGD:13792537 NCBI chr 7:141,386,391...141,424,375
Ensembl chr 7:141,386,391...141,424,343
JBrowse link
G Cers6 ceramide synthase 6 ISO
IBA
(PMID:17609214), (PMID:17977534)
PMID:21873635
(MGI:MGI:3696894|PMID:15823095), (MGI:MGI:5513027|PMID:23760501), (MGI:MGI:5755322|PMID:26620563)
RGD PMID:15823095, PMID:17609214, PMID:17977534, PMID:23760501, PMID:26620563, PMID:21873635 MGI:MGI:3696894, MGI:MGI:5513027, MGI:MGI:5755322, RGD:13792537 NCBI chr 3:55,094,240...55,338,370
Ensembl chr 3:55,094,637...55,338,445
JBrowse link
G Cyp4f39 cytochrome P450, family 4, subfamily f, polypeptide 39 ISO
IBA
(PMID:26056268)
PMID:21873635
RGD PMID:26056268, PMID:21873635 RGD:13792537 NCBI chr 7:14,435,024...14,514,960
Ensembl chr 7:14,441,476...14,515,212
JBrowse link
G Degs1 delta(4)-desaturase, sphingolipid 1 ISO
IBA
MGI:MGI:3529540 (MGI:MGI:5466789|PMID:22984457)
PMID:21873635
RGD PMID:22984457, PMID:21873635 MGI:MGI:5466789, RGD:13792537 NCBI chr13:100,665,265...100,672,731
Ensembl chr13:100,666,075...100,672,731
JBrowse link
G Degs2 delta(4)-desaturase, sphingolipid 2 ISO
IBA
(MGI:MGI:3694278|PMID:16571104)
PMID:21873635
RGD PMID:16571104, PMID:21873635 MGI:MGI:3694278, RGD:13792537 NCBI chr 6:132,591,968...132,608,600
Ensembl chr 6:132,591,969...132,608,600
JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 ISO (MGI:MGI:5532629|PMID:23689133) RGD PMID:23689133 MGI:MGI:5532629 NCBI chr 5:137,255,868...137,260,486
Ensembl chr 5:137,255,908...137,260,483
JBrowse link
G Fa2h fatty acid 2-hydroxylase ISS
ISO
GO_REF:0000024
(MGI:MGI:6245295|PMID:22517924)
(PMID:15337768)
UniProt
RGD
PMID:15337768, PMID:22517924 GO_REF:0000024, MGI:MGI:6245295 NCBI chr19:43,545,380...43,596,788
Ensembl chr19:43,545,378...43,596,801
JBrowse link
G Gba glucosylceramidase beta ISO (PMID:19279011) RGD PMID:19279011 NCBI chr 2:188,511,781...188,522,602
Ensembl chr 2:188,516,582...188,522,601
JBrowse link
G LOC498300 similar to degenerative spermatocyte homolog IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:99,369,102...99,374,051
Ensembl chr13:99,369,126...99,374,033
JBrowse link
G P2rx1 purinergic receptor P2X 1 ISO (MGI:MGI:3640029|PMID:16325464) RGD PMID:16325464 MGI:MGI:3640029 NCBI chr10:59,566,268...59,581,328
Ensembl chr10:59,566,223...59,581,325
JBrowse link
G P2rx7 purinergic receptor P2X 7 ISO (MGI:MGI:3640029|PMID:16325464) RGD PMID:16325464 MGI:MGI:3640029 NCBI chr12:39,353,613...39,396,042
Ensembl chr12:39,353,613...39,396,042
JBrowse link
G RGD1564463 similar to Mdes protein IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:99,374,006...99,395,804
Ensembl chr13:99,387,950...99,395,842
JBrowse link
G Samd8 sterile alpha motif domain containing 8 ISO
IBA
(PMID:19506037)
PMID:21873635
MGI:MGI:5749225 (MGI:MGI:5632043|PMID:25605874), (MGI:MGI:5707904|PMID:25667419)
RGD PMID:19506037, PMID:25605874, PMID:25667419, PMID:21873635 MGI:MGI:5632043, MGI:MGI:5707904, RGD:13792537 NCBI chr15:2,685,504...2,731,062
Ensembl chr15:2,685,511...2,731,462
JBrowse link
G Sgms1 sphingomyelin synthase 1 ISO
IBA
(MGI:MGI:5632043|PMID:25605874)
PMID:21873635
(PMID:25605874)
RGD PMID:25605874, PMID:21873635 MGI:MGI:5632043, RGD:13792537 NCBI chr 1:250,692,448...250,951,685
Ensembl chr 1:250,691,370...250,951,697
JBrowse link
G Sgms2 sphingomyelin synthase 2 ISO
IBA
IEA
MGI:MGI:4818459 (MGI:MGI:5632043|PMID:25605874)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:25605874, PMID:21873635 GO_REF:0000107, MGI:MGI:5632043, RGD:13792537 NCBI chr 2:236,458,276...236,530,667
Ensembl chr 2:236,458,279...236,480,502
JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 IMP
IBA
ISO
PMID:21873635
(PMID:18815062), (PMID:19279011)
RGD PMID:18815062, PMID:19279011, PMID:17261082, PMID:21873635 RGD:1601344, RGD:13792537 NCBI chr 1:170,383,682...170,387,525
Ensembl chr 1:170,383,682...170,387,524
JBrowse link
G Smpd2 sphingomyelin phosphodiesterase 2 IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:12473648, PMID:21873635 RGD:1581395, RGD:13792537 NCBI chr20:46,212,070...46,215,183
Ensembl chr20:46,211,892...46,215,120
JBrowse link
G Smpd4 sphingomyelin phosphodiesterase 4 IBA
ISO
PMID:21873635
(MGI:MGI:6450503|PMID:25180167)
(PMID:16517606), (PMID:25180167)
RGD PMID:16517606, PMID:25180167, PMID:21873635 MGI:MGI:6450503, RGD:13792537 NCBI chr11:87,522,971...87,546,687
Ensembl chr11:87,522,971...87,546,687
JBrowse link
G Smpd5 sphingomyelin phosphodiesterase 5 ISO (MGI:MGI:6450238|PMID:21183079) RGD PMID:21183079 MGI:MGI:6450238 NCBI chr 7:117,351,694...117,354,241
Ensembl chr 7:117,351,648...117,354,084
JBrowse link
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 ISO
IBA
MGI:MGI:3815115 (MGI:MGI:3814228|PMID:16216550)
PMID:21873635
(PMID:25691431)
RGD PMID:16216550, PMID:25691431, PMID:21873635 MGI:MGI:3814228, RGD:13792537 NCBI chr17:11,856,525...11,895,566
Ensembl chr17:11,856,525...11,895,566
JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 ISO
IBA
MGI:MGI:3815117 (MGI:MGI:3814228|PMID:16216550)
PMID:21873635
(PMID:25691431)
RGD PMID:16216550, PMID:25691431, PMID:21873635 MGI:MGI:3814228, RGD:13792537 NCBI chr 6:111,334,408...111,417,960
Ensembl chr 6:111,339,136...111,417,954
JBrowse link
G Sptlc3 serine palmitoyltransferase, long chain base subunit 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:132,560,437...132,689,313
Ensembl chr 3:132,560,506...132,692,737
JBrowse link
G Sptssa serine palmitoyltransferase, small subunit A ISO
IBA
(PMID:25691431)
PMID:21873635
RGD PMID:25691431, PMID:21873635 RGD:13792537 NCBI chr 6:75,540,132...75,551,545
Ensembl chr 6:75,540,174...75,551,625
JBrowse link
G Sptssb serine palmitoyltransferase, small subunit B ISO
IBA
MGI:MGI:5689843 (MGI:MGI:5689923|PMID:26438849)
PMID:21873635
RGD PMID:26438849, PMID:21873635 MGI:MGI:5689923, RGD:13792537 NCBI chr 2:166,654,036...166,682,325
Ensembl chr 2:166,654,043...166,682,325
JBrowse link
G Tlcd3b TLC domain containing 3B ISO (MGI:MGI:5490837|PMID:23275342) RGD PMID:23275342 MGI:MGI:5490837 NCBI chr 1:198,252,208...198,265,840
Ensembl chr 1:198,259,496...198,265,839
JBrowse link
ceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acer1 alkaline ceramidase 1 ISO (PMID:20207939)
(MGI:MGI:2670497|PMID:12783875), (MGI:MGI:5800647|PMID:27126290)
RGD PMID:12783875, PMID:20207939, PMID:27126290 MGI:MGI:2670497, MGI:MGI:5800647 NCBI chr 9:10,061,978...10,093,588
Ensembl chr 9:10,061,978...10,093,588
JBrowse link
G Acer2 alkaline ceramidase 2 ISO (PMID:16940153), (PMID:20207939) RGD PMID:16940153, PMID:20207939 NCBI chr 5:105,230,540...105,279,732
Ensembl chr 5:105,230,580...105,279,731
JBrowse link
G Acer3 alkaline ceramidase 3 ISO (MGI:MGI:5749603|PMID:26474409)
(PMID:20207939), (PMID:26792856), (PMID:30575723)
RGD PMID:20207939, PMID:26474409, PMID:26792856, PMID:30575723 MGI:MGI:5749603 NCBI chr 1:163,160,987...163,263,621
Ensembl chr 1:163,160,979...163,263,606
JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 IEA
ISO
ISS
GO_REF:0000107
(MGI:MGI:1267186|PMID:9653654), (MGI:MGI:5505361|PMID:23770692)
(PMID:10610716), (PMID:12815059)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:9653654, PMID:10610716, PMID:12815059, PMID:23770692 GO_REF:0000024, GO_REF:0000107, MGI:MGI:1267186, MGI:MGI:5505361 NCBI chr16:53,998,604...54,030,006
Ensembl chr16:53,998,560...54,040,836
JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 IDA
IBA
ISO
PMID:10488143
PMID:21873635
(MGI:MGI:3608219|PMID:16126722), (MGI:MGI:3640407|PMID:16380386), (MGI:MGI:6275120|PMID:10652340)
(PMID:10781606), (PMID:15946935), (PMID:16229686), (PMID:17475390), (PMID:19345744), (PMID:30154232)
PMID:15217782
PMID:15123644
RGD PMID:10652340, PMID:10781606, PMID:15946935, PMID:16126722, PMID:16229686, PMID:16380386, PMID:17475390, PMID:19345744, PMID:30154232, PMID:10488143, PMID:21873635, PMID:15217782, PMID:15123644 MGI:MGI:3608219, MGI:MGI:3640407, MGI:MGI:6275120, RGD:13838800, RGD:13792537, RGD:13838794, RGD:13838793 NCBI chr 1:250,557,042...250,665,083
Ensembl chr 1:250,557,044...250,630,677
JBrowse link
G Cel carboxyl ester lipase ISO
IEA
MGI:MGI:2180867 (MGI:MGI:2158596|PMID:11733511)
GO_REF:0000107
RGD
Ensembl
PMID:11733511 GO_REF:0000107, MGI:MGI:2158596 NCBI chr 3:7,134,021...7,141,522
Ensembl chr 3:7,134,021...7,141,522
JBrowse link
ceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asah2 N-acylsphingosine amidohydrolase 2 ISS
ISO
GO_REF:0000024
(PMID:26190575)
UniProt
RGD
PMID:26190575 GO_REF:0000024 NCBI chr 1:250,557,042...250,665,083
Ensembl chr 1:250,557,044...250,630,677
JBrowse link
G Cerk ceramide kinase ISO
IBA
(PMID:19501188)
PMID:21873635
RGD PMID:19501188, PMID:21873635 RGD:13792537 NCBI chr 7:127,015,162...127,058,056
Ensembl chr 7:127,015,162...127,058,056
JBrowse link
G Cert1 ceramide transporter 1 ISO MGI:MGI:3837565 (MGI:MGI:3836857|PMID:19139267) RGD PMID:19139267 MGI:MGI:3836857 NCBI chr 2:27,365,145...27,469,797
Ensembl chr 2:27,365,148...27,469,779
JBrowse link
G Cln8 CLN8, transmembrane ER and ERGIC protein ISO
ISS
(PMID:16086686)
GO_REF:0000024
RGD
UniProt
PMID:16086686 GO_REF:0000024 NCBI chr16:79,828,321...79,838,212
Ensembl chr16:79,828,324...79,838,212
JBrowse link
G Fut7 fucosyltransferase 7 ISO (PMID:9299472) RGD PMID:9299472 NCBI chr 3:2,637,281...2,646,497
Ensembl chr 3:2,642,531...2,646,648
JBrowse link
G Htra2 HtrA serine peptidase 2 IEP C2 ceramide RGD PMID:22296759 RGD:5688365 NCBI chr 4:113,883,671...113,886,833
Ensembl chr 4:113,883,670...113,886,994
JBrowse link
G LOC367454 similar to Alpha-(1,3)-fucosyltransferase (Galactoside 3-L-fucosyltransferase) (Fucosyltransferase 6) (FUCT-VI) ISO (PMID:17604274) RGD PMID:17604274 NCBI chr 9:10,309,050...10,318,899 JBrowse link
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 ISO
IBA
(PMID:20182505)
PMID:21873635
RGD PMID:20182505, PMID:21873635 RGD:13792537 NCBI chr 9:53,110,628...53,120,454
Ensembl chr 9:53,111,371...53,118,613
JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 ISO
IBA
(PMID:20182505)
PMID:21873635
RGD PMID:20182505, PMID:21873635 RGD:13792537 NCBI chr 7:3,242,991...3,246,085
Ensembl chr 7:3,242,991...3,246,071
JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 IEA
IBA
ISS
ISO
GO_REF:0000107
PMID:21873635
GO_REF:0000024
(PMID:20182505)
Ensembl
UniProt
RGD
PMID:20182505, PMID:21873635 GO_REF:0000024, GO_REF:0000107, RGD:13792537 NCBI chr10:86,545,910...86,554,478
Ensembl chr10:86,547,339...86,554,478
JBrowse link
G Pla2g15 phospholipase A2, group XV IDA
ISO
PMID:15294901
(MGI:MGI:2176649|PMID:11790796), (MGI:MGI:3694368|PMID:16837646), (MGI:MGI:4820669|PMID:20410020)
(PMID:20410020)
RGD PMID:11790796, PMID:16837646, PMID:20410020, PMID:15294901 MGI:MGI:2176649, MGI:MGI:3694368, MGI:MGI:4820669, RGD:1304489 NCBI chr19:38,129,666...38,146,958
Ensembl chr19:38,129,584...38,146,956
JBrowse link
G Plpp1 phospholipid phosphatase 1 ISO
IDA
IEA
(PMID:9305923), (PMID:9705349)
(MGI:MGI:6383560|PMID:10359651)
PMID:8663293
GO_REF:0000107
RGD
Ensembl
PMID:9305923, PMID:9705349, PMID:10359651, PMID:8663293, PMID:10359651 GO_REF:0000107, MGI:MGI:6383560, RGD:15090855, RGD:15090857 NCBI chr 2:44,664,076...44,726,820
Ensembl chr 2:44,664,124...44,726,689
JBrowse link
G Plpp2 phospholipid phosphatase 2 ISO
ISS
(PMID:9705349)
GO_REF:0000024
RGD
UniProt
PMID:9705349 GO_REF:0000024 NCBI chr 7:13,062,168...13,070,281
Ensembl chr 7:13,062,196...13,070,280
JBrowse link
G Plpp3 phospholipid phosphatase 3 ISO
IEA
ISS
(PMID:9305923), (PMID:9705349)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:9305923, PMID:9705349 GO_REF:0000024, GO_REF:0000107 NCBI chr 5:124,690,214...124,765,499
Ensembl chr 5:124,690,214...124,765,498
JBrowse link
G Psap prosaposin ISO MGI:MGI:3521746 (MGI:MGI:3512714|PMID:15345707), (MGI:MGI:3711591|PMID:17353235) RGD PMID:15345707, PMID:17353235 MGI:MGI:3512714, MGI:MGI:3711591 NCBI chr20:29,831,302...29,856,876
Ensembl chr20:29,831,314...29,856,875
JBrowse link
G Sgpl1 sphingosine-1-phosphate lyase 1 ISO
ISS
(PMID:14570870)
GO_REF:0000024
RGD
UniProt
PMID:14570870 GO_REF:0000024 NCBI chr20:30,699,936...30,769,178
Ensembl chr20:30,699,872...30,749,940
JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 ISO MGI:MGI:2183206 (MGI:MGI:5448760|PMID:23046545) RGD PMID:23046545 MGI:MGI:5448760 NCBI chr 1:170,383,682...170,387,525
Ensembl chr 1:170,383,682...170,387,524
JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 ISO
IEA
MGI:MGI:1856877 (MGI:MGI:5320806|PMID:22383528), (MGI:MGI:5448760|PMID:23046545)
GO_REF:0000107
RGD
Ensembl
PMID:22383528, PMID:23046545 GO_REF:0000107, MGI:MGI:5320806, MGI:MGI:5448760 NCBI chr19:38,237,963...38,321,572
Ensembl chr19:38,237,965...38,321,528
JBrowse link
G Smpd5 sphingomyelin phosphodiesterase 5 ISO (MGI:MGI:4833930|PMID:20378533) RGD PMID:20378533 MGI:MGI:4833930 NCBI chr 7:117,351,694...117,354,241
Ensembl chr 7:117,351,648...117,354,084
JBrowse link
ceramide phosphoethanolamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Samd8 sterile alpha motif domain containing 8 ISO (MGI:MGI:5707904|PMID:25667419) RGD PMID:25667419 MGI:MGI:5707904 NCBI chr15:2,685,504...2,731,062
Ensembl chr15:2,685,511...2,731,462
JBrowse link
G Sgms2 sphingomyelin synthase 2 ISO
IEA
(MGI:MGI:5707904|PMID:25667419)
GO_REF:0000107
RGD
Ensembl
PMID:25667419 GO_REF:0000107, MGI:MGI:5707904 NCBI chr 2:236,458,276...236,530,667
Ensembl chr 2:236,458,279...236,480,502
JBrowse link
galactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3galt1 Beta-1,3-galactosyltransferase 1 ISO (PMID:9582303) RGD PMID:9582303 NCBI chr 3:53,699,409...54,269,612
Ensembl chr 3:54,253,949...54,267,292
JBrowse link
G B3galt2 Beta-1,3-galactosyltransferase 2 ISO (PMID:9582303) RGD PMID:9582303 NCBI chr13:60,435,946...60,444,957
Ensembl chr13:60,435,946...60,444,957
JBrowse link
G B4galt3 beta-1,4-galactosyltransferase 3 ISO (PMID:9405390) RGD PMID:9405390 NCBI chr13:89,643,847...89,649,880
Ensembl chr13:89,643,881...89,649,906
JBrowse link
G Fa2h fatty acid 2-hydroxylase ISS
IEA
IMP
ISO
GO_REF:0000024
GO_REF:0000041
PMID:17901466
(MGI:MGI:3696647|PMID:15658937), (MGI:MGI:3826747|PMID:18815260)
UniProt
RGD
PMID:15658937, PMID:18815260, PMID:17901466 GO_REF:0000024, GO_REF:0000041, MGI:MGI:3696647, MGI:MGI:3826747, RGD:13825191 NCBI chr19:43,545,380...43,596,788
Ensembl chr19:43,545,378...43,596,801
JBrowse link
G Gal3st1 galactose-3-O-sulfotransferase 1 ISO
IBA
(MGI:MGI:1355015|PMID:10727929)
PMID:21873635
RGD PMID:10727929, PMID:21873635 MGI:MGI:1355015, RGD:13792537 NCBI chr14:84,231,473...84,247,371
Ensembl chr14:84,231,639...84,247,369
JBrowse link
G Ugt8 UDP glycosyltransferase 8 IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 2:229,644,373...229,718,678
Ensembl chr 2:229,644,382...229,718,659
JBrowse link
galactosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Galc galactosylceramidase ISO
IBA
MGI:MGI:1856218 (MGI:MGI:2183819|PMID:11371512), (MGI:MGI:78941|PMID:8769874)
(PMID:8399327)
PMID:21873635
RGD PMID:8399327, PMID:8769874, PMID:11371512, PMID:21873635 MGI:MGI:2183819, MGI:MGI:78941, RGD:13792537 NCBI chr 6:122,177,195...122,239,411
Ensembl chr 6:122,178,602...122,239,614
JBrowse link
G Gba3 glucosylceramidase beta 3 ISO (PMID:17595169) RGD PMID:17595169 NCBI chr14:64,390,793...64,535,213
Ensembl chr14:64,390,793...64,535,170
JBrowse link
G Psap prosaposin IEA
ISO
GO_REF:0000107
MGI:MGI:2183897 (MGI:MGI:2183819|PMID:11371512)
Ensembl
RGD
PMID:11371512 GO_REF:0000107, MGI:MGI:2183819 NCBI chr20:29,831,302...29,856,876
Ensembl chr20:29,831,314...29,856,875
JBrowse link
galactosylceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gal3st1 galactose-3-O-sulfotransferase 1 ISO (MGI:MGI:6436415|PMID:9030544) RGD PMID:9030544 MGI:MGI:6436415 NCBI chr14:84,231,473...84,247,371
Ensembl chr14:84,231,639...84,247,369
JBrowse link
ganglioside biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07013843.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 2:259,149,018...259,150,479 JBrowse link
G B3galt4 Beta-1,3-galactosyltransferase 4 IEA
ISO
GO_REF:0000107
(PMID:9582303)
Ensembl
RGD
PMID:9582303 GO_REF:0000107 NCBI chr20:5,446,104...5,447,679
Ensembl chr20:5,446,104...5,447,673
JBrowse link
G B4galnt1 beta-1,4-N-acetyl-galactosaminyl transferase 1 ISS
IBA
ISO
IDA
GO_REF:0000024
PMID:21873635
(PMID:1601877), (PMID:7487055), (PMID:7890749)
PMID:3140234
MGI:MGI:2158349|MGI:MGI:96074 (MGI:MGI:1331265|PMID:10021458), (MGI:MGI:83232|PMID:8855236)
UniProt
RGD
PMID:1601877, PMID:7487055, PMID:7890749, PMID:8855236, PMID:10021458, PMID:21873635, PMID:3140234 GO_REF:0000024, MGI:MGI:1331265, MGI:MGI:83232, RGD:13792537, RGD:21201261 NCBI chr 7:70,439,273...70,459,556
Ensembl chr 7:70,452,579...70,459,880
JBrowse link
G St6galnac3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:259,379,653...259,918,813
Ensembl chr 2:259,379,509...259,898,525
JBrowse link
G St6galnac4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:11,607,103...11,619,595
Ensembl chr 3:11,607,225...11,619,593
JBrowse link
G St6galnac5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:258,025,177...259,150,709
Ensembl chr 2:258,025,177...258,052,835
JBrowse link
G St6galnac6 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 ISO
IBA
(MGI:MGI:1354410|PMID:10702226)
PMID:21873635
RGD PMID:10702226, PMID:21873635 MGI:MGI:1354410, RGD:13792537 NCBI chr 3:11,620,050...11,641,460
Ensembl chr 3:11,629,556...11,641,466
JBrowse link
G St8sia2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 ISO (PMID:10766765) RGD PMID:10766765 NCBI chr 1:135,336,374...135,406,699
Ensembl chr 1:135,336,374...135,406,700
JBrowse link
G St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 ISO (PMID:10766765) RGD PMID:10766765 NCBI chr18:59,748,766...59,755,257
Ensembl chr18:59,748,444...59,755,226
JBrowse link
G St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 ISO (PMID:10766765) RGD PMID:10766765 NCBI chr 9:103,117,705...103,207,154
Ensembl chr 9:103,117,506...103,207,190
JBrowse link
G St8sia6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 ISO (MGI:MGI:2182536|PMID:11980897) RGD PMID:11980897 MGI:MGI:2182536 NCBI chr17:80,960,785...81,002,830
Ensembl chr17:80,960,785...81,002,838
JBrowse link
ganglioside biosynthetic process via lactosylceramide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4galt5 beta-1,4-galactosyltransferase 5 ISO (MGI:MGI:6196231|PMID:30114188) RGD PMID:30114188 MGI:MGI:6196231 NCBI chr 3:164,039,731...164,055,561
Ensembl chr 3:164,039,731...164,095,878
JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 ISS
ISO
IEA
GO_REF:0000024
(MGI:MGI:6196231|PMID:30114188)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:30114188 GO_REF:0000024, GO_REF:0000107, MGI:MGI:6196231 NCBI chr18:15,462,913...15,525,584
Ensembl chr18:15,462,913...15,525,579
JBrowse link
ganglioside catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gm2a GM2 ganglioside activator ISO
IBA
MGI:MGI:1861930 (MGI:MGI:894862|PMID:9223328)
PMID:21873635
RGD PMID:9223328, PMID:21873635 MGI:MGI:894862, RGD:13792537 NCBI chr10:40,438,394...40,450,927
Ensembl chr10:40,438,356...40,450,930
JBrowse link
G Hexa hexosaminidase subunit alpha ISO
ISS
MGI:MGI:1857181|MGI:MGI:2429698 (MGI:MGI:1271008|PMID:9645704), (MGI:MGI:69059|PMID:7937929), (MGI:MGI:78473|PMID:8789434), (MGI:MGI:894862|PMID:9223328)
GO_REF:0000024
(PMID:8123671), (PMID:8672428), (PMID:9694901)
RGD
UniProt
PMID:7937929, PMID:8123671, PMID:8672428, PMID:8789434, PMID:9223328, PMID:9645704, PMID:9694901 GO_REF:0000024, MGI:MGI:1271008, MGI:MGI:69059, MGI:MGI:78473, MGI:MGI:894862 NCBI chr 8:64,325,435...64,350,775
Ensembl chr 8:64,325,435...64,350,773
JBrowse link
G Hexb hexosaminidase subunit beta ISO
IEA
ISS
MGI:MGI:1857438|MGI:MGI:2429701 (MGI:MGI:1271008|PMID:9645704), (MGI:MGI:1331265|PMID:10021458), (MGI:MGI:2670850|PMID:12756243), (MGI:MGI:3041658|PMID:12657883), (MGI:MGI:3573807|PMID:15748167), (MGI:MGI:76816|PMID:8566348), (MGI:MGI:78473|PMID:8789434), (MGI:MGI:894862|PMID:9223328)
GO_REF:0000107
GO_REF:0000024
(PMID:8123671), (PMID:8672428)
RGD
Ensembl
UniProt
PMID:8123671, PMID:8566348, PMID:8672428, PMID:8789434, PMID:9223328, PMID:9645704, PMID:10021458, PMID:12657883, PMID:12756243, PMID:15748167 GO_REF:0000024, GO_REF:0000107, MGI:MGI:1271008, MGI:MGI:1331265, MGI:MGI:2670850, MGI:MGI:3041658, MGI:MGI:3573807, MGI:MGI:76816, MGI:MGI:78473, MGI:MGI:894862 NCBI chr 2:27,983,925...28,003,260
Ensembl chr 2:27,984,117...28,003,186
JBrowse link
G Neu1 neuraminidase 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:4,610,995...4,615,258
Ensembl chr20:4,610,995...4,615,247
JBrowse link
G Neu2 neuraminidase 2 IEA
ISO
IBA
ISS
GO_REF:0000107
(MGI:MGI:1354405|PMID:10713120)
(PMID:14613940), (PMID:22228546)
PMID:21873635
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:10713120, PMID:14613940, PMID:22228546, PMID:21873635 GO_REF:0000024, GO_REF:0000107, MGI:MGI:1354405, RGD:13792537 NCBI chr 9:94,702,095...94,724,903
Ensembl chr 9:94,702,129...94,724,902
JBrowse link
G Neu3 neuraminidase 3 ISS
ISO
IBA
GO_REF:0000024
(MGI:MGI:3765376|PMID:17708748)
(PMID:10861246), (PMID:11298736), (PMID:15847605), (PMID:17334392)
PMID:21873635
UniProt
RGD
PMID:10861246, PMID:11298736, PMID:15847605, PMID:17334392, PMID:17708748, PMID:21873635 GO_REF:0000024, MGI:MGI:3765376, RGD:13792537 NCBI chr 1:164,803,574...164,814,777
Ensembl chr 1:164,803,574...164,814,651
JBrowse link
G Neu4 neuraminidase 4 IBA
ISO
PMID:21873635
(MGI:MGI:4361102|PMID:19506080)
(PMID:15213228), (PMID:15847605)
RGD PMID:15213228, PMID:15847605, PMID:19506080, PMID:21873635 MGI:MGI:4361102, RGD:13792537 NCBI chr 9:101,284,902...101,290,558
Ensembl chr 9:101,284,902...101,290,558
JBrowse link
G NEWGENE_1308624 sialidase 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:101,003,455...101,008,365
Ensembl chr 9:101,005,082...101,008,170
JBrowse link
ganglioside metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln6 CLN6, transmembrane ER protein ISO (PMID:16857350) RGD PMID:16857350 NCBI chr 8:67,733,215...67,748,170
Ensembl chr 8:67,733,215...67,748,172
JBrowse link
G Gm2a GM2 ganglioside activator IDA RGD PMID:9770472 RGD:1598995 NCBI chr10:40,438,394...40,450,927
Ensembl chr10:40,438,356...40,450,930
JBrowse link
G Itgb8 integrin subunit beta 8 ISO MGI:MGI:2180548 (MGI:MGI:3607039|PMID:16251442) RGD PMID:16251442 MGI:MGI:3607039 NCBI chr 6:147,089,280...147,172,846
Ensembl chr 6:147,094,097...147,172,813
JBrowse link
globoside biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A4galt alpha 1,4-galactosyltransferase (P blood group) ISO MGI:MGI:3624807|MGI:MGI:5445373 (MGI:MGI:3623723|PMID:16476743), (MGI:MGI:5445364|PMID:22875802) RGD PMID:16476743, PMID:22875802 MGI:MGI:3623723, MGI:MGI:5445364 NCBI chr 7:124,085,832...124,110,440
Ensembl chr 7:124,085,834...124,089,385
JBrowse link
globoside metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gbgt1 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group) ISO (PMID:8855242) RGD PMID:8855242 NCBI chr 3:7,076,582...7,079,652 JBrowse link
glucosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fa2h fatty acid 2-hydroxylase ISS
ISO
GO_REF:0000024
(MGI:MGI:5285470|PMID:21628453)
UniProt
RGD
PMID:21628453 GO_REF:0000024, MGI:MGI:5285470 NCBI chr19:43,545,380...43,596,788
Ensembl chr19:43,545,378...43,596,801
JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase ISO
IBA
ISS
(PMID:8643456)
PMID:21873635
(MGI:MGI:2180222|PMID:10430909), (MGI:MGI:3603060|PMID:16109770), (MGI:MGI:5448789|PMID:22851168), (MGI:MGI:5510915|PMID:23748427)
GO_REF:0000024
RGD
UniProt
PMID:8643456, PMID:10430909, PMID:16109770, PMID:22851168, PMID:23748427, PMID:21873635 GO_REF:0000024, MGI:MGI:2180222, MGI:MGI:3603060, MGI:MGI:5448789, MGI:MGI:5510915, RGD:13792537 NCBI chr 5:76,376,722...76,419,564
Ensembl chr 5:76,386,836...76,419,560
JBrowse link
glucosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gba glucosylceramidase beta ISO
IBA
(PMID:16293621), (PMID:19279011), (PMID:21700325), (PMID:24022302), (PMID:24211208), (PMID:9201993)
PMID:21873635
(MGI:MGI:5141165|PMID:21700325), (MGI:MGI:5501380|PMID:23707074), (MGI:MGI:6271235|PMID:24211208)
RGD PMID:9201993, PMID:16293621, PMID:19279011, PMID:21700325, PMID:23707074, PMID:24022302, PMID:24211208, PMID:21873635 MGI:MGI:5141165, MGI:MGI:5501380, MGI:MGI:6271235, RGD:13792537 NCBI chr 2:188,511,781...188,522,602
Ensembl chr 2:188,516,582...188,522,601
JBrowse link
G Gba2 glucosylceramidase beta 2 IEA
ISO
ISS
GO_REF:0000002
(MGI:MGI:3690511|PMID:17080196), (MGI:MGI:5484792|PMID:23250757)
(PMID:17080196), (PMID:30308956)
GO_REF:0000024
InterPro
RGD
UniProt
PMID:17080196, PMID:23250757, PMID:30308956 GO_REF:0000002, GO_REF:0000024, MGI:MGI:3690511, MGI:MGI:5484792 NCBI chr 5:59,068,081...59,079,719
Ensembl chr 5:59,068,081...59,079,719
JBrowse link
G Gba3 glucosylceramidase beta 3 NOT ISO (PMID:20728381)
(PMID:17595169), (PMID:26724485)
RGD PMID:17595169, PMID:20728381, PMID:26724485 NCBI chr14:64,390,793...64,535,213
Ensembl chr14:64,390,793...64,535,170
JBrowse link
glucosylceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gba glucosylceramidase beta ISO (MGI:MGI:3762988|PMID:17954912), (MGI:MGI:3795074|PMID:18346921) RGD PMID:17954912, PMID:18346921 MGI:MGI:3762988, MGI:MGI:3795074 NCBI chr 2:188,511,781...188,522,602
Ensembl chr 2:188,516,582...188,522,601
JBrowse link
G Psap prosaposin IEA
ISO
GO_REF:0000107
(MGI:MGI:3711591|PMID:17353235)
Ensembl
RGD
PMID:17353235 GO_REF:0000107, MGI:MGI:3711591 NCBI chr20:29,831,302...29,856,876
Ensembl chr20:29,831,314...29,856,875
JBrowse link
glycosphingolipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A3galt2 alpha 1,3-galactosyltransferase 2 IDA
ISO
MGI:MGI:1347344|MGI:MGI:3512453 (MGI:MGI:5445364|PMID:22875802)
PMID:12626403
RGD PMID:22875802, PMID:10854427, PMID:12626403 MGI:MGI:5445364, RGD:1299594, RGD:632674 NCBI chr 5:146,933,592...146,945,882
Ensembl chr 5:146,933,592...146,945,880
JBrowse link
G A4galt alpha 1,4-galactosyltransferase (P blood group) IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:124,085,832...124,110,440
Ensembl chr 7:124,085,834...124,089,385
JBrowse link
G B4galnt1 beta-1,4-N-acetyl-galactosaminyl transferase 1 IDA PMID:1606358 UniProt PMID:1606358 RGD:21201272 NCBI chr 7:70,439,273...70,459,556
Ensembl chr 7:70,452,579...70,459,880
JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 IDA RGD PMID:9593693 RGD:70807 NCBI chr18:15,462,913...15,525,584
Ensembl chr18:15,462,913...15,525,579
JBrowse link
G St6galnac5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 ISO (MGI:MGI:1346847|PMID:10521438) RGD PMID:10521438 MGI:MGI:1346847 NCBI chr 2:258,025,177...259,150,709
Ensembl chr 2:258,025,177...258,052,835
JBrowse link
G St8sia5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 IDA PMID:1606358 UniProt PMID:1606358 RGD:21201272 NCBI chr18:73,564,010...73,630,256
Ensembl chr18:73,564,247...73,625,137
JBrowse link
G Ugt8 UDP glycosyltransferase 8 TAS RGD PMID:7521399 RGD:70050 NCBI chr 2:229,644,373...229,718,678
Ensembl chr 2:229,644,382...229,718,659
JBrowse link
glycosphingolipid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gla galactosidase, alpha ISO (PMID:10838196), (PMID:8804427) RGD PMID:8804427, PMID:10838196 NCBI chr  X:105,405,915...105,417,331
Ensembl chr  X:105,406,792...105,417,323
JBrowse link
glycosphingolipid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4galnt1 beta-1,4-N-acetyl-galactosaminyl transferase 1 ISO
IDA
MGI:MGI:2158349 (MGI:MGI:3797995|PMID:18308723)
PMID:3140234
RGD PMID:18308723, PMID:3140234 MGI:MGI:3797995, RGD:21201261 NCBI chr 7:70,439,273...70,459,556
Ensembl chr 7:70,452,579...70,459,880
JBrowse link
G Bax BCL2 associated X, apoptosis regulator ISO
IEA
MGI:MGI:1857429 (MGI:MGI:3797995|PMID:18308723)
GO_REF:0000107
RGD
Ensembl
PMID:18308723 GO_REF:0000107, MGI:MGI:3797995 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Crem cAMP responsive element modulator ISO MGI:MGI:2158921 (MGI:MGI:3797995|PMID:18308723) RGD PMID:18308723 MGI:MGI:3797995 NCBI chr17:57,021,704...57,090,888
Ensembl chr17:57,031,766...57,090,888
JBrowse link
G Hexb hexosaminidase subunit beta ISO MGI:MGI:2429701 (MGI:MGI:78473|PMID:8789434) RGD PMID:8789434 MGI:MGI:78473 NCBI chr 2:27,983,925...28,003,260
Ensembl chr 2:27,984,117...28,003,186
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase ISO MGI:MGI:1856232 (MGI:MGI:3797995|PMID:18308723) RGD PMID:18308723 MGI:MGI:3797995 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610
JBrowse link
G Map7 microtubule-associated protein 7 ISO MGI:MGI:1889849 (MGI:MGI:3797995|PMID:18308723) RGD PMID:18308723 MGI:MGI:3797995 NCBI chr 1:15,620,665...15,748,203
Ensembl chr 1:15,620,653...15,748,203
JBrowse link
G St6galnac3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 ISO (PMID:17123352) RGD PMID:17123352 NCBI chr 2:259,379,653...259,918,813
Ensembl chr 2:259,379,509...259,898,525
JBrowse link
G St6galnac6 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 ISO (PMID:17123352) RGD PMID:17123352 NCBI chr 3:11,620,050...11,641,460
Ensembl chr 3:11,629,556...11,641,466
JBrowse link
glycosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gba3 glucosylceramidase beta 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:64,390,793...64,535,213
Ensembl chr14:64,390,793...64,535,170
JBrowse link
G Gla galactosidase, alpha ISO
IBA
MGI:MGI:1861794 (MGI:MGI:1859538|PMID:10841515), (MGI:MGI:1860035|PMID:10840053), (MGI:MGI:2155538|PMID:11752062), (MGI:MGI:3525994|PMID:15629890), (MGI:MGI:86774|PMID:9122231)
PMID:21873635
RGD PMID:9122231, PMID:10840053, PMID:10841515, PMID:11752062, PMID:15629890, PMID:21873635 MGI:MGI:1859538, MGI:MGI:1860035, MGI:MGI:2155538, MGI:MGI:3525994, MGI:MGI:86774, RGD:13792537 NCBI chr  X:105,405,915...105,417,331
Ensembl chr  X:105,406,792...105,417,323
JBrowse link
G Naga alpha-N-acetylgalactosaminidase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:123,563,047...123,572,074
Ensembl chr 7:123,563,059...123,572,082
JBrowse link
glycosylceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G St6galnac3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 ISO
IEA
(PMID:17123352)
GO_REF:0000107
RGD
Ensembl
PMID:17123352 GO_REF:0000107 NCBI chr 2:259,379,653...259,918,813
Ensembl chr 2:259,379,509...259,898,525
JBrowse link
G St6galnac6 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 ISO (PMID:17123352) RGD PMID:17123352 NCBI chr 3:11,620,050...11,641,460
Ensembl chr 3:11,629,556...11,641,466
JBrowse link
lactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4galt6 beta-1,4-galactosyltransferase 6 IEA
ISO
GO_REF:0000107
(PMID:10320813)
Ensembl
RGD
PMID:10320813 GO_REF:0000107 NCBI chr18:15,462,913...15,525,584
Ensembl chr18:15,462,913...15,525,579
JBrowse link
negative regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 ISO
IBA
(PMID:25691431)
PMID:21873635
RGD PMID:25691431, PMID:21873635 RGD:13792537 NCBI chr 9:53,110,628...53,120,454
Ensembl chr 9:53,111,371...53,118,613
JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 ISO
IBA
(PMID:25691431)
PMID:21873635
RGD PMID:25691431, PMID:21873635 RGD:13792537 NCBI chr 7:3,242,991...3,246,085
Ensembl chr 7:3,242,991...3,246,071
JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 ISO
IBA
IEA
(MGI:MGI:5638294|PMID:25691431)
PMID:21873635
GO_REF:0000107
(PMID:25691431)
RGD
Ensembl
PMID:25691431, PMID:21873635 GO_REF:0000107, MGI:MGI:5638294, RGD:13792537 NCBI chr10:86,545,910...86,554,478
Ensembl chr10:86,547,339...86,554,478
JBrowse link
G Sphk1 sphingosine kinase 1 ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:MGI:6294167|PMID:16118219)
(PMID:16118219)
UniProt
Ensembl
RGD
PMID:16118219 GO_REF:0000024, GO_REF:0000107, MGI:MGI:6294167 NCBI chr10:105,498,728...105,504,401
Ensembl chr10:105,498,728...105,504,393
JBrowse link
negative regulation of sphingolipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 ISO
IMP
IEA
(PMID:24201375)
GO_REF:0000107
RGD
Ensembl
PMID:24201375, PMID:24201375 GO_REF:0000107, RGD:14697729 NCBI chr 3:2,648,787...2,668,770
Ensembl chr 3:2,648,885...2,668,809
JBrowse link
G Atg7 autophagy related 7 ISO MGI:MGI:2176073|MGI:MGI:3587769 (MGI:MGI:5613260|PMID:25332431) RGD PMID:25332431 MGI:MGI:5613260 NCBI chr 4:146,570,113...146,777,093
Ensembl chr 4:146,598,413...146,777,124
JBrowse link
phytosphingosine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acer3 alkaline ceramidase 3 ISO
IBA
(PMID:11356846), (PMID:20068046)
PMID:21873635
RGD PMID:11356846, PMID:20068046, PMID:21873635 RGD:13792537 NCBI chr 1:163,160,987...163,263,621
Ensembl chr 1:163,160,979...163,263,606
JBrowse link
positive regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn1 cellular communication network factor 1 ISO
IEA
(MGI:MGI:3849354|PMID:19364818)
GO_REF:0000107
RGD
Ensembl
PMID:19364818 GO_REF:0000107, MGI:MGI:3849354 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312
JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 ISS
ISO
GO_REF:0000024
(MGI:MGI:4947032|PMID:21177474)
UniProt
RGD
PMID:21177474 GO_REF:0000024, MGI:MGI:4947032 NCBI chr10:108,095,131...108,099,483
Ensembl chr10:108,095,131...108,099,483
JBrowse link
G Pla2g6 phospholipase A2 group VI IDA RGD PMID:18936091 RGD:6482750 NCBI chr 7:120,519,479...120,559,716
Ensembl chr 7:120,519,467...120,559,347
JBrowse link
G Prkcd protein kinase C, delta ISO
IEA
(PMID:19279011)
GO_REF:0000107
RGD
Ensembl
PMID:19279011 GO_REF:0000107 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746
JBrowse link
G Sirt3 sirtuin 3 ISO (MGI:MGI:5755322|PMID:26620563) RGD PMID:26620563 MGI:MGI:5755322 NCBI chr 1:213,613,502...213,636,061
Ensembl chr 1:213,613,513...213,635,546
JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 IMP RGD PMID:20096352 RGD:10041064 NCBI chr19:38,237,963...38,321,572
Ensembl chr19:38,237,965...38,321,528
JBrowse link
G Sphk2 sphingosine kinase 2 ISO (PMID:16118219)
(MGI:MGI:6294167|PMID:16118219)
RGD PMID:16118219 MGI:MGI:6294167 NCBI chr 1:101,692,972...101,700,604
Ensembl chr 1:101,692,973...101,697,277
JBrowse link
positive regulation of glucosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkcd protein kinase C, delta ISO
IEA
(PMID:19279011)
GO_REF:0000107
RGD
Ensembl
PMID:19279011 GO_REF:0000107 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746
JBrowse link
positive regulation of sphingomyelin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 ISS
ISO
GO_REF:0000024
(MGI:MGI:4947032|PMID:21177474)
UniProt
RGD
PMID:21177474 GO_REF:0000024, MGI:MGI:4947032 NCBI chr10:108,095,131...108,099,483
Ensembl chr10:108,095,131...108,099,483
JBrowse link
G Prkcd protein kinase C, delta ISO
IEA
(PMID:19279011)
GO_REF:0000107
RGD
Ensembl
PMID:19279011 GO_REF:0000107 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746
JBrowse link
regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 ISO MGI:MGI:1913862 (MGI:MGI:6393026|PMID:31880535) RGD PMID:31880535 MGI:MGI:6393026 NCBI chr 9:53,110,628...53,120,454
Ensembl chr 9:53,111,371...53,118,613
JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 ISO MGI:MGI:2137691|MGI:MGI:2181669|MGI:MGI:6382064 (MGI:MGI:6393026|PMID:31880535) RGD PMID:31880535 MGI:MGI:6393026 NCBI chr10:86,545,910...86,554,478
Ensembl chr10:86,547,339...86,554,478
JBrowse link
G Samd8 sterile alpha motif domain containing 8 ISO (PMID:19506037) RGD PMID:19506037 NCBI chr15:2,685,504...2,731,062
Ensembl chr15:2,685,511...2,731,462
JBrowse link
regulation of sphingolipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 ISO MGI:MGI:1913862 (MGI:MGI:6393026|PMID:31880535) RGD PMID:31880535 MGI:MGI:6393026 NCBI chr 9:53,110,628...53,120,454
Ensembl chr 9:53,111,371...53,118,613
JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 ISO MGI:MGI:2137691|MGI:MGI:2181669|MGI:MGI:2445707|MGI:MGI:6343506|MGI:MGI:6382064 (MGI:MGI:5926671|PMID:28275141), (MGI:MGI:6393026|PMID:31880535) RGD PMID:28275141, PMID:31880535 MGI:MGI:5926671, MGI:MGI:6393026 NCBI chr10:86,545,910...86,554,478
Ensembl chr10:86,547,339...86,554,478
JBrowse link
sphinganine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 ISO MGI:MGI:3815115 (MGI:MGI:3846467|PMID:19416652) RGD PMID:19416652 MGI:MGI:3846467 NCBI chr17:11,856,525...11,895,566
Ensembl chr17:11,856,525...11,895,566
JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 ISO (MGI:MGI:1098386|PMID:9363775) RGD PMID:9363775 MGI:MGI:1098386 NCBI chr 6:111,334,408...111,417,960
Ensembl chr 6:111,339,136...111,417,954
JBrowse link
sphinganine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Degs2 delta(4)-desaturase, sphingolipid 2 ISO
IBA
SGD:S000002705 (MGI:MGI:3505861|PMID:11937514), (MGI:MGI:3694278|PMID:16571104)
PMID:21873635
RGD PMID:11937514, PMID:16571104, PMID:21873635 MGI:MGI:3505861, MGI:MGI:3694278, RGD:13792537 NCBI chr 6:132,591,968...132,608,600
Ensembl chr 6:132,591,969...132,608,600
JBrowse link
sphinganine-1-phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sphk2 sphingosine kinase 2 ISO
IBA
(PMID:10751414), (PMID:19729656)
PMID:21873635
(MGI:MGI:1860308|PMID:10751414)
RGD PMID:10751414, PMID:19729656, PMID:21873635 MGI:MGI:1860308, RGD:13792537 NCBI chr 1:101,692,972...101,700,604
Ensembl chr 1:101,692,973...101,697,277
JBrowse link
sphinganine-1-phosphate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sgpp1 sphingosine-1-phosphate phosphatase 1 ISO (MGI:MGI:1932564|PMID:10859351), (MGI:MGI:2176350|PMID:11756451) RGD PMID:10859351, PMID:11756451 MGI:MGI:1932564, MGI:MGI:2176350 NCBI chr 6:98,675,324...98,696,492
Ensembl chr 6:98,675,326...98,695,988
JBrowse link
sphingoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sptlc3 serine palmitoyltransferase, long chain base subunit 3 ISO (PMID:19648650) RGD PMID:19648650 NCBI chr 3:132,560,437...132,689,313
Ensembl chr 3:132,560,506...132,692,737
JBrowse link
sphingolipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acer1 alkaline ceramidase 1 ISO (PMID:17713573) RGD PMID:17713573 NCBI chr 9:10,061,978...10,093,588
Ensembl chr 9:10,061,978...10,093,588
JBrowse link
G Cerkl ceramide kinase-like ISO MGI:MGI:5461515 (MGI:MGI:5571022|PMID:23501591) RGD PMID:23501591 MGI:MGI:5571022 NCBI chr 3:66,268,835...66,395,615
Ensembl chr 3:66,268,947...66,394,764
JBrowse link
G Cers1 ceramide synthase 1 ISO (PMID:12105227) RGD PMID:12105227 NCBI chr16:20,845,580...20,860,789
Ensembl chr16:20,845,576...20,860,789
JBrowse link
G Cers2 ceramide synthase 2 ISO (MGI:MGI:3696894|PMID:15823095) RGD PMID:15823095 MGI:MGI:3696894 NCBI chr 2:196,487,656...196,495,930
Ensembl chr 2:196,487,656...196,496,986
JBrowse link
G Cers3 ceramide synthase 3 ISO (MGI:MGI:3692343|PMID:16753040) RGD PMID:16753040 MGI:MGI:3692343 NCBI chr 1:127,706,618...127,781,041
Ensembl chr 1:127,648,234...127,781,017
JBrowse link
G Cers4 ceramide synthase 4 ISO (MGI:MGI:3696894|PMID:15823095) RGD PMID:15823095 MGI:MGI:3696894 NCBI chr12:4,439,750...4,474,759
Ensembl chr12:4,439,750...4,474,729
JBrowse link
G Cers5 ceramide synthase 5 ISO (MGI:MGI:3696894|PMID:15823095) RGD PMID:15823095 MGI:MGI:3696894 NCBI chr 7:141,386,391...141,424,375
Ensembl chr 7:141,386,391...141,424,343
JBrowse link
G Cers6 ceramide synthase 6 ISO (MGI:MGI:3696894|PMID:15823095) RGD PMID:15823095 MGI:MGI:3696894 NCBI chr 3:55,094,240...55,338,370
Ensembl chr 3:55,094,637...55,338,445
JBrowse link
G Degs2 delta(4)-desaturase, sphingolipid 2 ISO SGD:S000002705 (MGI:MGI:3505861|PMID:11937514) RGD PMID:11937514 MGI:MGI:3505861 NCBI chr 6:132,591,968...132,608,600
Ensembl chr 6:132,591,969...132,608,600
JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 ISO
IBA
(PMID:20937905)
PMID:21873635
(MGI:MGI:4944052|PMID:20253178)
RGD PMID:20253178, PMID:20937905, PMID:21873635 MGI:MGI:4944052, RGD:13792537 NCBI chr 5:137,255,868...137,260,486
Ensembl chr 5:137,255,908...137,260,483
JBrowse link
G Elovl2 ELOVL fatty acid elongase 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:21,382,461...21,422,413
Ensembl chr17:21,382,455...21,422,407
JBrowse link
G Elovl3 ELOVL fatty acid elongase 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:265,883,353...265,887,181
Ensembl chr 1:265,883,355...265,887,226
JBrowse link
G Elovl4 ELOVL fatty acid elongase 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:91,310,690...91,338,625
Ensembl chr 8:91,310,630...91,338,843
JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:85,220,941...85,287,449
Ensembl chr 8:85,259,982...85,285,983
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:234,187,490...234,296,124
Ensembl chr 2:234,189,105...234,296,145
Ensembl chr 2:234,189,105...234,296,145
JBrowse link
G Elovl7 ELOVL fatty acid elongase 7 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:40,373,211...40,386,643
Ensembl chr 2:40,373,211...40,386,669
JBrowse link
G Hacd1 3-hydroxyacyl-CoA dehydratase 1 ISO
IBA
UniProtKB:P40857 (PMID:18554506)
PMID:21873635
RGD PMID:18554506, PMID:21873635 RGD:13792537 NCBI chr17:81,173,238...81,196,012
Ensembl chr17:81,173,713...81,187,739
JBrowse link
G Hacd2 3-hydroxyacyl-CoA dehydratase 2 ISO
IBA
UniProtKB:P40857 (PMID:18554506)
PMID:21873635
RGD PMID:18554506, PMID:21873635 RGD:13792537 NCBI chr11:68,893,684...68,985,635
Ensembl chr11:68,894,445...68,989,988
JBrowse link
G Hacd3 3-hydroxyacyl-CoA dehydratase 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:70,471,572...70,509,874
Ensembl chr 8:70,471,572...70,509,874
JBrowse link
G Hacd4 3-hydroxyacyl-CoA dehydratase 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:106,728,401...106,758,068
Ensembl chr 5:106,732,513...106,758,032
JBrowse link
G Kdsr 3-ketodihydrosphingosine reductase ISO
IBA
SGD:S000000469 (MGI:MGI:3522414|PMID:15328338)
PMID:21873635
RGD PMID:15328338, PMID:21873635 MGI:MGI:3522414, RGD:13792537 NCBI chr13:26,779,386...26,812,271
Ensembl chr13:26,780,633...26,812,215
JBrowse link
G LOC102549542 elongation of very long chain fatty acids protein 6-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:234,375,172...234,486,639
Ensembl chr 2:234,375,315...234,483,149
JBrowse link
G Samd8 sterile alpha motif domain containing 8 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:2,685,504...2,731,062
Ensembl chr15:2,685,511...2,731,462
JBrowse link
G Sgms1 sphingomyelin synthase 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:250,692,448...250,951,685
Ensembl chr 1:250,691,370...250,951,697
JBrowse link
G Sgms2 sphingomyelin synthase 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:236,458,276...236,530,667
Ensembl chr 2:236,458,279...236,480,502
JBrowse link
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 ISO (PMID:25332431) RGD PMID:25332431 NCBI chr17:11,856,525...11,895,566
Ensembl chr17:11,856,525...11,895,566
JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 ISO
ISS
(PMID:25332431), (PMID:26573920)
GO_REF:0000024
(MGI:MGI:5917779|PMID:28698261)
RGD
UniProt
PMID:25332431, PMID:26573920, PMID:28698261 GO_REF:0000024, MGI:MGI:5917779 NCBI chr 6:111,334,408...111,417,960
Ensembl chr 6:111,339,136...111,417,954
JBrowse link
G Sptssb serine palmitoyltransferase, small subunit B ISO MGI:MGI:5689843 (MGI:MGI:5689923|PMID:26438849) RGD PMID:26438849 MGI:MGI:5689923 NCBI chr 2:166,654,036...166,682,325
Ensembl chr 2:166,654,043...166,682,325
JBrowse link
sphingolipid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07028989.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr10:1,622,573...1,674,701 JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 ISO
IEA
ISS
(PMID:14500380)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:14500380 GO_REF:0000024, GO_REF:0000107 NCBI chr 7:94,479,931...94,563,086
Ensembl chr 7:94,480,396...94,563,001
JBrowse link
G Pdxdc1 pyridoxal-dependent decarboxylase domain containing 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:3,232,794...3,321,438
Ensembl chr10:3,232,794...3,321,412
JBrowse link
G Sgpl1 sphingosine-1-phosphate lyase 1 ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:24809814), (PMID:28165339)
UniProt
RGD
PMID:24809814, PMID:28165339, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr20:30,699,936...30,769,178
Ensembl chr20:30,699,872...30,749,940
JBrowse link
G Smpd2 sphingomyelin phosphodiesterase 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:46,212,070...46,215,183
Ensembl chr20:46,211,892...46,215,120
JBrowse link
sphingomyelin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 ISO MGI:MGI:1913862 (MGI:MGI:6393026|PMID:31880535) RGD PMID:31880535 MGI:MGI:6393026 NCBI chr 9:53,110,628...53,120,454
Ensembl chr 9:53,111,371...53,118,613
JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 ISO MGI:MGI:2137691|MGI:MGI:2181669|MGI:MGI:6382064 (MGI:MGI:6393026|PMID:31880535) RGD PMID:31880535 MGI:MGI:6393026 NCBI chr10:86,545,910...86,554,478
Ensembl chr10:86,547,339...86,554,478
JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase ISO (MGI:MGI:5707904|PMID:25667419) RGD PMID:25667419 MGI:MGI:5707904 NCBI chr10:46,339,821...46,404,640
Ensembl chr10:46,339,821...46,404,642
JBrowse link
G Sgms1 sphingomyelin synthase 1 ISS
ISO
IBA
GO_REF:0000024
(MGI:MGI:6221394|PMID:27892528)
(PMID:14685263), (PMID:14976195), (PMID:17982138)
PMID:21873635
HGNC
RGD
PMID:14685263, PMID:14976195, PMID:17982138, PMID:27892528, PMID:21873635 GO_REF:0000024, MGI:MGI:6221394, RGD:13792537 NCBI chr 1:250,692,448...250,951,685
Ensembl chr 1:250,691,370...250,951,697
JBrowse link
G Sgms2 sphingomyelin synthase 2 IEA
ISO
IBA
GO_REF:0000107
(MGI:MGI:5707904|PMID:25667419), (MGI:MGI:6221394|PMID:27892528)
(PMID:14685263), (PMID:17982138)
PMID:21873635
Ensembl
RGD
PMID:14685263, PMID:17982138, PMID:25667419, PMID:27892528, PMID:21873635 GO_REF:0000107, MGI:MGI:5707904, MGI:MGI:6221394, RGD:13792537 NCBI chr 2:236,458,276...236,530,667
Ensembl chr 2:236,458,279...236,480,502
JBrowse link
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 ISO MGI:MGI:3815115 (MGI:MGI:3814228|PMID:16216550), (MGI:MGI:5749304|PMID:26301690) RGD PMID:16216550, PMID:26301690 MGI:MGI:3814228, MGI:MGI:5749304 NCBI chr17:11,856,525...11,895,566
Ensembl chr17:11,856,525...11,895,566
JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 ISO MGI:MGI:3815117 (MGI:MGI:3814228|PMID:16216550) RGD PMID:16216550 MGI:MGI:3814228 NCBI chr 6:111,334,408...111,417,960
Ensembl chr 6:111,339,136...111,417,954
JBrowse link
sphingomyelin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:108,095,131...108,099,483
Ensembl chr10:108,095,131...108,099,483
JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 ISO
IBA
(PMID:18815062)
(MGI:MGI:5529577|PMID:23973266)
PMID:21873635
RGD PMID:18815062, PMID:23973266, PMID:21873635 MGI:MGI:5529577, RGD:13792537 NCBI chr 1:170,383,682...170,387,525
Ensembl chr 1:170,383,682...170,387,524
JBrowse link
G Smpd2 sphingomyelin phosphodiesterase 2 ISO (MGI:MGI:5529577|PMID:23973266) RGD PMID:23973266 MGI:MGI:5529577 NCBI chr20:46,212,070...46,215,183
Ensembl chr20:46,211,892...46,215,120
JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 ISO
IEA
(MGI:MGI:5529577|PMID:23973266)
GO_REF:0000107
RGD
Ensembl
PMID:23973266 GO_REF:0000107, MGI:MGI:5529577 NCBI chr19:38,237,963...38,321,572
Ensembl chr19:38,237,965...38,321,528
JBrowse link
G Smpd4 sphingomyelin phosphodiesterase 4 IBA
ISO
PMID:21873635
(MGI:MGI:6450503|PMID:25180167)
(PMID:16517606), (PMID:25180167)
RGD PMID:16517606, PMID:25180167, PMID:21873635 MGI:MGI:6450503, RGD:13792537 NCBI chr11:87,522,971...87,546,687
Ensembl chr11:87,522,971...87,546,687
JBrowse link
G Smpd5 sphingomyelin phosphodiesterase 5 ISO (MGI:MGI:6450238|PMID:21183079) RGD PMID:21183079 MGI:MGI:6450238 NCBI chr 7:117,351,694...117,354,241
Ensembl chr 7:117,351,648...117,354,084
JBrowse link
G Smpdl3a sphingomyelin phosphodiesterase, acid-like 3A NOT ISO
ISS
(PMID:26783088)
GO_REF:0000024
RGD
UniProt
PMID:26783088 GO_REF:0000024 NCBI chr20:40,779,022...40,800,842
Ensembl chr20:40,778,927...40,800,868
JBrowse link
G Smpdl3b sphingomyelin phosphodiesterase, acid-like 3B IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:150,925,150...150,946,994
Ensembl chr 5:150,925,370...150,949,931
JBrowse link
sphingomyelin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 ISS
ISO
GO_REF:0000024
(PMID:12671034), (PMID:12885774), (PMID:28292932)
UniProt
RGD
PMID:12671034, PMID:12885774, PMID:28292932 GO_REF:0000024 NCBI chr10:108,095,131...108,099,483
Ensembl chr10:108,095,131...108,099,483
JBrowse link
G Smpd2 sphingomyelin phosphodiesterase 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:46,212,070...46,215,183
Ensembl chr20:46,211,892...46,215,120
JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 IBA
ISO
ISS
PMID:21873635
(MGI:MGI:1858672|PMID:10823942), (MGI:MGI:6450311|PMID:21550973)
GO_REF:0000024
RGD
UniProt
PMID:10823942, PMID:21550973, PMID:21873635 GO_REF:0000024, MGI:MGI:1858672, MGI:MGI:6450311, RGD:13792537 NCBI chr19:38,237,963...38,321,572
Ensembl chr19:38,237,965...38,321,528
JBrowse link
G Smpd5 sphingomyelin phosphodiesterase 5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:117,351,694...117,354,241
Ensembl chr 7:117,351,648...117,354,084
JBrowse link
sphingosine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 ISO
IEA
(PMID:26510981)
GO_REF:0000107
RGD
Ensembl
PMID:26510981 GO_REF:0000107 NCBI chr 3:2,648,787...2,668,770
Ensembl chr 3:2,648,885...2,668,809
JBrowse link
G Acer1 alkaline ceramidase 1 ISO (PMID:17713573), (PMID:20207939), (PMID:20628055)
(MGI:MGI:5800647|PMID:27126290), (MGI:MGI:6107252|PMID:29056331)
RGD PMID:17713573, PMID:20207939, PMID:20628055, PMID:27126290, PMID:29056331 MGI:MGI:5800647, MGI:MGI:6107252 NCBI chr 9:10,061,978...10,093,588
Ensembl chr 9:10,061,978...10,093,588
JBrowse link
G Acer2 alkaline ceramidase 2 ISO (PMID:16940153), (PMID:20089856), (PMID:20207939), (PMID:20628055)
(MGI:MGI:6116621|PMID:29401619)
RGD PMID:16940153, PMID:20089856, PMID:20207939, PMID:20628055, PMID:29401619 MGI:MGI:6116621 NCBI chr 5:105,230,540...105,279,732
Ensembl chr 5:105,230,580...105,279,731
JBrowse link
G Acer3 alkaline ceramidase 3 ISO (PMID:20068046), (PMID:20207939), (PMID:26792856)
(MGI:MGI:5749603|PMID:26474409)
RGD PMID:20068046, PMID:20207939, PMID:26474409, PMID:26792856 MGI:MGI:5749603 NCBI chr 1:163,160,987...163,263,621
Ensembl chr 1:163,160,979...163,263,606
JBrowse link
G Agk acylglycerol kinase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:68,483,345...68,561,518
Ensembl chr 4:68,483,320...68,560,801
JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 IEA
ISO
ISS
GO_REF:0000107
(PMID:10610716), (PMID:12815059)
GO_REF:0000024
(MGI:MGI:1267186|PMID:9653654)
Ensembl
RGD
UniProt
PMID:9653654, PMID:10610716, PMID:12815059 GO_REF:0000024, GO_REF:0000107, MGI:MGI:1267186 NCBI chr16:53,998,604...54,030,006
Ensembl chr16:53,998,560...54,040,836
JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 IDA
IBA
ISO
PMID:10488143
PMID:21873635
(MGI:MGI:3608219|PMID:16126722), (MGI:MGI:3640407|PMID:16380386), (MGI:MGI:6275120|PMID:10652340)
(PMID:30154232)
PMID:15217782
PMID:15123644
RGD PMID:10652340, PMID:16126722, PMID:16380386, PMID:30154232, PMID:10488143, PMID:21873635, PMID:15217782, PMID:15123644 MGI:MGI:3608219, MGI:MGI:3640407, MGI:MGI:6275120, RGD:13838800, RGD:13792537, RGD:13838794, RGD:13838793 NCBI chr 1:250,557,042...250,665,083
Ensembl chr 1:250,557,044...250,630,677
JBrowse link
G Gba glucosylceramidase beta ISO (PMID:19279011) RGD PMID:19279011 NCBI chr 2:188,511,781...188,522,602
Ensembl chr 2:188,516,582...188,522,601
JBrowse link
G Sphk1 sphingosine kinase 1 ISO
IBA
IEA
UniProtKB:Q9NRA0 (PMID:23106337)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:23106337, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr10:105,498,728...105,504,401
Ensembl chr10:105,498,728...105,504,393
JBrowse link
G Sphk2 sphingosine kinase 2 ISO
IBA
UniProtKB:Q9NYA1 (PMID:23106337)
PMID:21873635
RGD PMID:23106337, PMID:21873635 RGD:13792537 NCBI chr 1:101,692,972...101,700,604
Ensembl chr 1:101,692,973...101,697,277
JBrowse link
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 ISO
IBA
MGI:MGI:3815115 (MGI:MGI:3814228|PMID:16216550)
PMID:21873635
RGD PMID:16216550, PMID:21873635 MGI:MGI:3814228, RGD:13792537 NCBI chr17:11,856,525...11,895,566
Ensembl chr17:11,856,525...11,895,566
JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 ISO
IBA
MGI:MGI:3815117 (MGI:MGI:3814228|PMID:16216550)
PMID:21873635
RGD PMID:16216550, PMID:21873635 MGI:MGI:3814228, RGD:13792537 NCBI chr 6:111,334,408...111,417,960
Ensembl chr 6:111,339,136...111,417,954
JBrowse link
G Sptlc3 serine palmitoyltransferase, long chain base subunit 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:132,560,437...132,689,313
Ensembl chr 3:132,560,506...132,692,737
JBrowse link
sphingosine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asah2 N-acylsphingosine amidohydrolase 2 ISS
ISO
GO_REF:0000024
(PMID:10781606), (PMID:15946935), (PMID:16229686), (PMID:17475390), (PMID:26190575)
UniProt
RGD
PMID:10781606, PMID:15946935, PMID:16229686, PMID:17475390, PMID:26190575 GO_REF:0000024 NCBI chr 1:250,557,042...250,665,083
Ensembl chr 1:250,557,044...250,630,677
JBrowse link
G Plpp1 phospholipid phosphatase 1 ISO
IDA
IEA
(PMID:9705349)
(MGI:MGI:6383560|PMID:10359651)
PMID:8663293
GO_REF:0000107
RGD
Ensembl
PMID:9705349, PMID:10359651, PMID:8663293, PMID:10359651 GO_REF:0000107, MGI:MGI:6383560, RGD:15090855, RGD:15090857 NCBI chr 2:44,664,076...44,726,820
Ensembl chr 2:44,664,124...44,726,689
JBrowse link
G Plpp2 phospholipid phosphatase 2 ISO
ISS
(PMID:9705349)
GO_REF:0000024
RGD
UniProt
PMID:9705349 GO_REF:0000024 NCBI chr 7:13,062,168...13,070,281
Ensembl chr 7:13,062,196...13,070,280
JBrowse link
G Plpp3 phospholipid phosphatase 3 ISO
IEA
ISS
(PMID:9305923), (PMID:9705349)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:9305923, PMID:9705349 GO_REF:0000024, GO_REF:0000107 NCBI chr 5:124,690,214...124,765,499
Ensembl chr 5:124,690,214...124,765,498
JBrowse link
G Sgpp1 sphingosine-1-phosphate phosphatase 1 ISO
IBA
(MGI:MGI:2176350|PMID:11756451)
PMID:21873635
RGD PMID:11756451, PMID:21873635 MGI:MGI:2176350, RGD:13792537 NCBI chr 6:98,675,324...98,696,492
Ensembl chr 6:98,675,326...98,695,988
JBrowse link
G Sgpp2 sphingosine-1-phosphate phosphatase 2 ISO
IBA
(PMID:12411432)
PMID:21873635
RGD PMID:12411432, PMID:21873635 RGD:13792537 NCBI chr 9:84,203,094...84,321,269
Ensembl chr 9:84,203,072...84,319,874
JBrowse link
G Sphk1 sphingosine kinase 1 ISO
ISS
(PMID:20577214)
GO_REF:0000024
RGD
UniProt
PMID:20577214 GO_REF:0000024 NCBI chr10:105,498,728...105,504,401
Ensembl chr10:105,498,728...105,504,393
JBrowse link
G Sphk2 sphingosine kinase 2 ISO MGI:MGI:3580701 (MGI:MGI:3608224|PMID:16093248), (MGI:MGI:3703830|PMID:17346996) RGD PMID:16093248, PMID:17346996 MGI:MGI:3608224, MGI:MGI:3703830 NCBI chr 1:101,692,972...101,700,604
Ensembl chr 1:101,692,973...101,697,277
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    metabolic process 12256
      nitrogen compound metabolic process 10342
        organonitrogen compound metabolic process 7132
          sphingolipid metabolic process 137
            ceramide metabolic process + 95
            ceramide phosphoethanolamine metabolic process + 2
            glycosphingolipid metabolic process + 46
            inositol phosphoceramide metabolic process + 0
            sphinganine-1-phosphate metabolic process + 2
            sphingoid metabolic process + 20
            sphingolipid biosynthetic process + 86
            sphingolipid catabolic process + 34
            sphingomyelin metabolic process + 16
Path 2
Term Annotations click to browse term
  biological_process 20014
    metabolic process 12256
      primary metabolic process 10901
        lipid metabolic process 1378
          cellular lipid metabolic process 1057
            membrane lipid metabolic process 187
              sphingolipid metabolic process 137
                ceramide metabolic process + 95
                ceramide phosphoethanolamine metabolic process + 2
                glycosphingolipid metabolic process + 46
                inositol phosphoceramide metabolic process + 0
                sphinganine-1-phosphate metabolic process + 2
                sphingoid metabolic process + 20
                sphingolipid biosynthetic process + 86
                sphingolipid catabolic process + 34
                sphingomyelin metabolic process + 16
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.