Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of B cell activation
go back to main search page
Accession:GO:0050869 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of B cell activation.
Synonyms:exact_synonym: down regulation of B cell activation;   downregulation of B cell activation;   negative regulation of B lymphocyte activation
 narrow_synonym: inhibition of B cell activation

GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
negative regulation of B cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bank1 B cell scaffold protein with ankyrin repeats 1 acts_upstream_of_or_within ISO (PMID:16546095) MGI PMID:16546095 NCBI chrNW_004955496:6,267,618...6,511,195
Ensembl chrNW_004955496:6,267,551...6,470,948 		JBrowse link
G Btk Bruton tyrosine kinase ISO RGD PMID:25545336 RGD:151665128 NCBI chrNW_004955503:7,483,819...7,515,085
Ensembl chrNW_004955503:7,482,793...7,515,120 		JBrowse link
G Fas Fas cell surface death receptor acts_upstream_of_or_within ISO (PMID:6610701) MGI PMID:6610701 NCBI chrNW_004955425:3,961,671...3,987,513
Ensembl chrNW_004955425:3,961,013...3,987,455 		JBrowse link
G Foxj1 forkhead box J1 involved_in ISO (MGI:3589323|PMID:16002694) BHF-UCL PMID:16002694 MGI:3589323 NCBI chrNW_004955506:6,127,551...6,132,302
Ensembl chrNW_004955506:6,127,551...6,132,302 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D acts_upstream_of_or_within ISO (PMID:10704460) MGI PMID:10704460 NCBI chrNW_004955453:2,938,659...3,037,211
Ensembl chrNW_004955453:2,938,659...3,037,211 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (MGI:4460047|PMID:20519653) ARUK-UCL PMID:20519653 MGI:4460047 NCBI chrNW_004955452:9,335,481...9,358,177
Ensembl chrNW_004955452:9,334,587...9,358,444 		JBrowse link
G Samsn1 SAM domain, SH3 domain and nuclear localization signals 1 involved_in ISO (MGI:4437539|PMID:19923443) UniProt PMID:19923443 MGI:4437539 NCBI chrNW_004955407:16,329,838...16,377,763
Ensembl chrNW_004955407:16,329,288...16,378,062 		JBrowse link
G Tbc1d10c TBC1 domain family member 10C acts_upstream_of_or_within ISO (PMID:23109291) MGI PMID:23109291 NCBI chrNW_004955422:18,069,686...18,075,795
Ensembl chrNW_004955422:18,069,686...18,075,794 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (MGI:4946158|PMID:21088135) BHF-UCL PMID:21088135 MGI:4946158 NCBI chrNW_004955436:21,566,591...21,581,551
Ensembl chrNW_004955436:21,566,423...21,578,469 		JBrowse link
negative regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flt3 fms related receptor tyrosine kinase 3 acts_upstream_of_or_within ISO (PMID:16618805) MGI PMID:16618805 NCBI chrNW_004955497:7,357,533...7,441,215
Ensembl chrNW_004955497:7,357,212...7,461,439 		JBrowse link
G Hmgb3 high mobility group box 3 acts_upstream_of_or_within ISO (PMID:12714519) MGI PMID:12714519 NCBI chrNW_004955498:6,633,540...6,640,393
Ensembl chrNW_004955498:6,633,336...6,640,459 		JBrowse link
G Id2 inhibitor of DNA binding 2 acts_upstream_of_or_within ISO (PMID:18523151) MGI PMID:18523151 NCBI chrNW_004955487:878,326...880,783
Ensembl chrNW_004955487:878,326...880,783 		JBrowse link
G Sfrp1 secreted frizzled related protein 1 involved_in ISO (PMID:18941195)
(MGI:3814493|PMID:18941195)		 UniProt PMID:18941195 MGI:3814493 NCBI chrNW_004955536:1,663,721...1,702,678
Ensembl chrNW_004955536:1,663,344...1,703,514 		JBrowse link
negative regulation of B cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chrNW_004955412:10,422,753...10,531,406
Ensembl chrNW_004955412:10,426,135...10,530,545 		JBrowse link
G Btk Bruton tyrosine kinase acts_upstream_of_or_within ISO (PMID:7680896) MGI PMID:7680896 NCBI chrNW_004955503:7,483,819...7,515,085
Ensembl chrNW_004955503:7,482,793...7,515,120 		JBrowse link
G Btla B and T lymphocyte associated acts_upstream_of_or_within ISO (PMID:12796776) MGI PMID:12796776 NCBI chrNW_004955427:12,804,467...12,837,178
Ensembl chrNW_004955427:12,802,581...12,837,031 		JBrowse link
G Casp3 caspase 3 acts_upstream_of_or_within ISO (PMID:12970760) MGI PMID:12970760 NCBI chrNW_004955403:24,315,712...24,326,271 JBrowse link
G Cd24 CD24 molecule acts_upstream_of_or_within ISO (PMID:8920854) MGI PMID:8920854 NCBI chrNW_004955411:32,270,881...32,275,236
Ensembl chrNW_004955411:32,270,881...32,275,236 		JBrowse link
G Cd300a CD300a molecule involved_in ISO (PMID:21482706) UniProt PMID:21482706 NCBI chrNW_004955553:1,335,854...1,356,001
Ensembl chrNW_004955553:1,336,227...1,460,376 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte associated protein 4 involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chrNW_004955457:11,028,707...11,034,898
Ensembl chrNW_004955457:11,028,698...11,073,460 		JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb acts_upstream_of_or_within ISO (PMID:12385742), (PMID:8552190) MGI PMID:8552190 PMID:12385742 NCBI chrNW_004955462:14,639,396...14,653,801 JBrowse link
G Il10 interleukin 10 acts_upstream_of_or_within ISO (PMID:9184696) MGI PMID:9184696 NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D acts_upstream_of_or_within ISO (PMID:10704460) MGI PMID:10704460 NCBI chrNW_004955453:2,938,659...3,037,211
Ensembl chrNW_004955453:2,938,659...3,037,211 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (MGI:894972|PMID:9252121) UniProt PMID:9252121 MGI:894972 NCBI chrNW_004955454:15,025,967...15,111,142
Ensembl chrNW_004955454:15,035,979...15,111,142 		JBrowse link
G Pawr pro-apoptotic WT1 regulator acts_upstream_of_or_within ISO (PMID:12970181) MGI PMID:12970181 NCBI chrNW_004955405:18,434,711...18,540,710
Ensembl chrNW_004955405:18,434,711...18,540,710 		JBrowse link
G Pkn1 protein kinase N1 acts_upstream_of_or_within ISO (PMID:23223530) MGI PMID:23223530 NCBI chrNW_004955415:33,040,868...33,062,753
Ensembl chrNW_004955415:33,043,918...33,063,567 		JBrowse link
G Pten phosphatase and tensin homolog acts_upstream_of_or_within ISO (PMID:16027169) MGI PMID:16027169 NCBI chrNW_004955425:5,007,811...5,091,829
Ensembl chrNW_004955425:5,014,147...5,091,829 		JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in ISO (MGI:5284769|PMID:18172933) BHF-UCL PMID:18172933 MGI:5284769 NCBI chrNW_004955406:14,053,122...14,123,023
Ensembl chrNW_004955406:14,053,122...14,123,029 		JBrowse link
G Tnfrsf13b TNF receptor superfamily member 13B acts_upstream_of_or_within ISO (PMID:15240667) MGI PMID:15240667 NCBI chrNW_004955577:930,612...971,698 JBrowse link
G Tnfrsf21 TNF receptor superfamily member 21 involved_in ISO (MGI:3628730|PMID:12515813) UniProt PMID:12515813 MGI:3628730 NCBI chrNW_004955437:11,877,051...11,915,220
Ensembl chrNW_004955437:11,876,895...11,915,460 		JBrowse link
G Tsc2 TSC complex subunit 2 acts_upstream_of_or_within ISO (PMID:16027169) MGI PMID:16027169 NCBI chrNW_004955442:15,178,356...15,216,978
Ensembl chrNW_004955442:15,178,487...15,216,362 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor TYROBP involved_in ISO (PMID:21727189)
(MGI:5295549|PMID:21727189)		 UniProt PMID:21727189 MGI:5295549 NCBI chrNW_004955468:2,673,657...2,677,633
Ensembl chrNW_004955468:2,673,980...2,677,321 		JBrowse link
negative regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Parp3 poly(ADP-ribose) polymerase family member 3 involved_in ISO (MGI:6214451|PMID:26000965) UniProt PMID:26000965 MGI:6214451 NCBI chrNW_004955532:3,591,484...3,597,549
Ensembl chrNW_004955532:3,591,499...3,597,549 		JBrowse link
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6 transcription repressor acts_upstream_of_or_within ISO (PMID:10490661) MGI PMID:10490661 NCBI chrNW_004955420:19,998,960...20,021,200
Ensembl chrNW_004955420:19,998,742...20,022,259 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO (PMID:16275384) MGI PMID:16275384 NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606 		JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within ISO (PMID:17137798) MGI PMID:17137798 NCBI chrNW_004955415:11,643,846...11,666,131
Ensembl chrNW_004955415:11,643,846...11,666,131 		JBrowse link
negative regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6 transcription repressor acts_upstream_of_or_within ISO (PMID:15240705) MGI PMID:15240705 NCBI chrNW_004955420:19,998,960...20,021,200
Ensembl chrNW_004955420:19,998,742...20,022,259 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12362
    immune system process 1980
      leukocyte activation 888
        lymphocyte activation 720
          B cell activation 256
            negative regulation of B cell activation 34
              negative regulation of B cell differentiation + 5
              negative regulation of B cell proliferation 19
              negative regulation of isotype switching + 4
Path 2
Term Annotations click to browse term
  biological_process 12362
    biological regulation 8888
      regulation of biological process 8622
        regulation of multicellular organismal process 2854
          negative regulation of multicellular organismal process 1129
            negative regulation of cell activation 197
              negative regulation of leukocyte activation 179
                negative regulation of lymphocyte activation 155
                  negative regulation of B cell activation 34
                    negative regulation of B cell differentiation + 5
                    negative regulation of B cell proliferation 19
                    negative regulation of isotype switching + 4
paths to the root