Symbol:
Tsc2
Name:
TSC complex subunit 2
RGD ID:
8926086
Description:
ENCODES a protein that exhibits 14-3-3 protein binding (ortholog); GTPase activator activity (ortholog); Hsp90 protein binding (ortholog); INVOLVED IN anoikis (ortholog); B cell proliferation (ortholog); cell population proliferation (ortholog); PARTICIPATES IN mitogen activated protein kinase signaling pathway; mTOR signaling pathway; the extracellular signal-regulated Raf/Mek/Erk signaling pathway; ASSOCIATED WITH Acute Hepatitis (ortholog); acute myeloid leukemia (ortholog); Alzheimer's disease (ortholog); FOUND IN caveola (ortholog); cell projection (ortholog); cytoplasm (ortholog)
Type:
protein-coding
RefSeq Status:
MODEL
Previously known as:
tuberin; tuberous sclerosis 2
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955442 15,178,487 - 15,216,362 (-) Ensembl ChiLan1.0 ChiLan1.0 NW_004955442 15,178,356 - 15,216,978 (-) NCBI ChiLan1.0 ChiLan1.0
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Imported Annotations - PID (archival)
Tsc2 Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955442 15,178,487 - 15,216,362 (-) Ensembl ChiLan1.0 ChiLan1.0 NW_004955442 15,178,356 - 15,216,978 (-) NCBI ChiLan1.0 ChiLan1.0
TSC2 Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 16 2,047,985 - 2,089,491 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 16 2,047,967 - 2,089,491 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 16 2,097,986 - 2,139,492 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 16 2,037,991 - 2,078,714 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 16 2,038,599 - 2,078,713 NCBI Celera 16 2,310,097 - 2,350,826 (+) NCBI Celera Cytogenetic Map 16 p13.3 NCBI HuRef 16 2,022,255 - 2,063,441 (+) NCBI HuRef CHM1_1 16 2,097,965 - 2,138,628 (+) NCBI CHM1_1 T2T-CHM13v2.0 16 2,067,794 - 2,109,598 (+) NCBI T2T-CHM13v2.0
Tsc2 Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 17 24,814,788 - 24,851,607 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 17 24,814,790 - 24,851,604 (-) Ensembl GRCm39 Ensembl GRCm38 17 24,595,816 - 24,632,676 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 17 24,595,816 - 24,632,630 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 17 24,732,882 - 24,769,574 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 17 24,323,537 - 24,360,229 (-) NCBI MGSCv36 mm8 Celera 17 25,113,932 - 25,155,030 (-) NCBI Celera Cytogenetic Map 17 A3.3 NCBI cM Map 17 12.41 NCBI
Tsc2 Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 10 14,125,679 - 14,160,317 (-) NCBI GRCr8 mRatBN7.2 10 13,621,135 - 13,655,773 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 10 13,621,136 - 13,655,951 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 10 18,367,921 - 18,402,464 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 10 17,856,767 - 17,891,310 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 10 13,355,965 - 13,390,509 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 10 13,962,006 - 13,996,684 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 10 13,961,947 - 13,996,584 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 10 13,778,990 - 13,813,725 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 10 13,848,210 - 13,883,189 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 10 13,848,241 - 13,882,689 NCBI Celera 10 13,301,129 - 13,335,713 (-) NCBI Celera Cytogenetic Map 10 q12 NCBI
TSC2 Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 18 2,258,660 - 2,298,636 (-) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 16 6,040,481 - 6,080,306 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 16 615,776 - 655,411 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 16 2,135,696 - 2,175,569 (+) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 16 2,135,696 - 2,175,569 (+) Ensembl panpan1.1 panPan2
TSC2 Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 6 38,865,509 - 38,898,977 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 6 38,865,507 - 38,898,960 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 6 40,104,412 - 40,137,701 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 6 39,173,764 - 39,207,052 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 6 39,173,766 - 39,207,060 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 6 38,858,570 - 38,891,854 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 6 38,830,888 - 38,864,172 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 6 39,309,683 - 39,342,799 (-) NCBI UU_Cfam_GSD_1.0
Tsc2 Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024409344 104,716,067 - 104,751,311 (+) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936694 1,958,154 - 1,993,363 (-) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936694 1,958,152 - 1,993,373 (-) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
TSC2 Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 3 39,898,925 - 39,937,371 (-) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 3 39,898,924 - 39,935,579 (-) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 3 42,245,971 - 42,282,092 (+) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
TSC2 Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 5 1,946,534 - 1,985,168 (+) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 5 1,946,927 - 1,987,682 (+) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666068 29,078,990 - 29,119,738 (-) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Tsc2
.
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
Ensembl Acc Id:
ENSCLAT00000019639 ⟹ ENSCLAP00000019447
Type:
CODING
Position:
Chinchilla Assembly Chr Position (strand) Source ChiLan1.0 Ensembl NW_004955442 15,178,487 - 15,216,362 (-) Ensembl
RefSeq Acc Id:
XM_005391468 ⟹ XP_005391525
Type:
CODING
Position:
Chinchilla Assembly Chr Position (strand) Source ChiLan1.0 NW_004955442 15,178,356 - 15,216,978 (-) NCBI
Sequence:
CTCCGCACTGGCCCACCCCCGGAAGTGAGGGTGGTGCTTCCTGCGGCGGCTTCGCGGGGGTCCCGGGAGTGAGCCCTTCTCAGCGGCGGGGGGCCGCACGGGAGGAGCCCTCTCCTGGGCCCCTCCCC
hide sequence
RefSeq Acc Id:
XM_005391470 ⟹ XP_005391527
Type:
CODING
Position:
Chinchilla Assembly Chr Position (strand) Source ChiLan1.0 NW_004955442 15,178,356 - 15,216,978 (-) NCBI
Sequence:
CTCCGCACTGGCCCACCCCCGGAAGTGAGGGTGGTGCTTCCTGCGGCGGCTTCGCGGGGGTCCC
hide sequence
RefSeq Acc Id:
XM_013517657 ⟹ XP_013373111
Type:
CODING
Position:
Chinchilla Assembly Chr Position (strand) Source ChiLan1.0 NW_004955442 15,178,356 - 15,216,978 (-) NCBI
Sequence:
CTCCGCACTGGCCCACCCCCGGAAGTGAGGGTGGTGCTTCCTGCGGCGGCTTCGCGGGGGTCCC
hide sequence
RefSeq Acc Id:
XM_013517658 ⟹ XP_013373112
Type:
CODING
Position:
Chinchilla Assembly Chr Position (strand) Source ChiLan1.0 NW_004955442 15,178,356 - 15,216,978 (-) NCBI
Sequence:
CTCCGCACTGGCCCACCCCCGGAAGTGAGGGTGGTGCTTCCTGCGGCGGCTTCGCGGGGGTCCCGGGAGTGAGCCCTTCTCAGCGGCGGGGGGCCGCACGGGAGGAGCCCTCTCCTGGGCCCCTCCCC
hide sequence
RefSeq Acc Id:
XM_013517660 ⟹ XP_013373114
Type:
CODING
Position:
Chinchilla Assembly Chr Position (strand) Source ChiLan1.0 NW_004955442 15,178,356 - 15,216,978 (-) NCBI
Sequence:
CTCCGCACTGGCCCACCCCCGGAAGTGAGGGTGGTGCTTCCTGCGGCGGCTTCGCGGGGGTCCC
hide sequence
RefSeq Acc Id:
XM_013517661 ⟹ XP_013373115
Type:
CODING
Position:
Chinchilla Assembly Chr Position (strand) Source ChiLan1.0 NW_004955442 15,178,356 - 15,216,978 (-) NCBI
Sequence:
CTCCGCACTGGCCCACCCCCGGAAGTGAGGGTGGTGCTTCCTGCGGCGGCTTCGCGGGGGTCCCGGGAGTGAGCCCTTCTCAGCGGCGGGGGGCCGCACGGGAGGAGCCCTCTCCTGGGCCCCTCCCC
hide sequence
RefSeq Acc Id:
XM_013517662 ⟹ XP_013373116
Type:
CODING
Position:
Chinchilla Assembly Chr Position (strand) Source ChiLan1.0 NW_004955442 15,178,356 - 15,216,978 (-) NCBI
Sequence:
CTCCGCACTGGCCCACCCCCGGAAGTGAGGGTGGTGCTTCCTGCGGCGGCTTCGCGGGGGTCCC
hide sequence
RefSeq Acc Id:
XP_005391525 ⟸ XM_005391468
- Peptide Label:
isoform X1
- UniProtKB:
A0A8C2VRI8 (UniProtKB/TrEMBL)
- Sequence:
MAKPANKDSGLKEKFKTFLGLRTTRPNPRSAEGNQTEFIITAEILRELSVECGLNNRIRVIGQICEVAKTKKFEEHAVEALWKAVEDLLQPERPPEARHAVLALLKAIVQGQGDRLGILRALFFKVIK
hide sequence
RefSeq Acc Id:
XP_005391527 ⟸ XM_005391470
- Peptide Label:
isoform X5
- UniProtKB:
A0A8C2VRI8 (UniProtKB/TrEMBL)
- Sequence:
MAKPANKDSGLKEKFKTFLGLRTTRPNPRSAEGNQTEFIITAEILRELSVECGLNNRIRVIGQI
hide sequence
RefSeq Acc Id:
XP_013373114 ⟸ XM_013517660
- Peptide Label:
isoform X4
- UniProtKB:
A0A8C2VRI8 (UniProtKB/TrEMBL)
- Sequence:
MAKPANKDSGLKEKFKTFLGLRTTRPNPRSAEGNQTEFIITAEILRELSVECGLNNRIRVIGQI
hide sequence
RefSeq Acc Id:
XP_013373116 ⟸ XM_013517662
- Peptide Label:
isoform X7
- UniProtKB:
A0A8C2VRI8 (UniProtKB/TrEMBL)
- Sequence:
MAKPANKDSGLKEKFKTFLGLRTTRPNPRSAEGNQTEFIITAEILRELSVECGLNNRIRVIGQICEVAKTKKFEEHAVEALWKAVEDLLQPERPPEARHAVLALLKAIVQGQGDRLGILRALFFKVIK
hide sequence
RefSeq Acc Id:
XP_013373115 ⟸ XM_013517661
- Peptide Label:
isoform X6
- UniProtKB:
A0A8C2VRI8 (UniProtKB/TrEMBL)
- Sequence:
MAKPANKDSGLKEKFKTFLGLRTTRPNPRSAEGNQTEFIITAEILRELSVECGLNNRIRVIGQICEVAKTKKFEEHAVEALWKAVEDLLQPERPPEARHAVLALLKAIVQGQGDRLGILRALFFKVIK
hide sequence
RefSeq Acc Id:
XP_013373112 ⟸ XM_013517658
- Peptide Label:
isoform X3
- UniProtKB:
A0A8C2VRI8 (UniProtKB/TrEMBL)
- Sequence:
MAKPANKDSGLKEKFKTFLGLRTTRPNPRSAEGNQTEFIITAEILRELSVECGLNNRIRVIGQICEVAKTKKFEEHAVEALWKAVEDLLQPERPPEARHAVLALLKAIVQGQGDRLGILRALFFKVIK
hide sequence
RefSeq Acc Id:
XP_013373111 ⟸ XM_013517657
- Peptide Label:
isoform X2
- UniProtKB:
A0A8C2VRI8 (UniProtKB/TrEMBL)
- Sequence:
MAKPANKDSGLKEKFKTFLGLRTTRPNPRSAEGNQTEFIITAEILRELSVECGLNNRIRVIGQI
hide sequence
Ensembl Acc Id:
ENSCLAP00000019447 ⟸ ENSCLAT00000019639
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2017-07-04
Tsc2
TSC complex subunit 2
tuberous sclerosis 2
Symbol and/or name change
5135510 APPROVED
