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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of B cell differentiation
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Accession:GO:0045578 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of B cell differentiation.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: down regulation of B cell differentiation;   downregulation of B cell differentiation;   negative regulation of B lymphocyte differentiation
 narrow_synonym: inhibition of B cell differentiation
 related_synonym: negative regulation of B cell development



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negative regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flt3 Fms related receptor tyrosine kinase 3 acts_upstream_of_or_within ISO (MGI:3623701|PMID:16618805) RGD PMID:16618805 MGI:3623701 NCBI chr12:7,623,658...7,699,474
Ensembl chr12:7,623,930...7,699,474
JBrowse link
G Hmgb3 high mobility group box 3 acts_upstream_of_or_within ISO (MGI:2670545|PMID:12714519) RGD PMID:12714519 MGI:2670545 NCBI chr  X:149,296,309...149,301,294
Ensembl chr  X:149,296,375...149,301,292
JBrowse link
G Id2 inhibitor of DNA binding 2 acts_upstream_of_or_within ISO MGI:2384134 (MGI:3805135|PMID:18523151) RGD PMID:18523151 MGI:3805135 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in ISO
IEA
(PMID:18941195)
GO_REF:0000107
(MGI:3814493|PMID:18941195)
RGD
Ensembl
PMID:18941195 GO_REF:0000107 MGI:3814493 NCBI chr16:68,575,763...68,613,905
Ensembl chr16:68,575,763...68,614,286
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19512
    immune system process 2869
      leukocyte activation 1078
        lymphocyte activation 893
          lymphocyte differentiation 427
            B cell differentiation 158
              negative regulation of B cell differentiation 4
                negative regulation of B-1 B cell differentiation 0
                negative regulation of central B cell anergy 0
                negative regulation of central B cell deletion 0
                negative regulation of plasma cell differentiation 0
Path 2
Term Annotations click to browse term
  biological_process 19512
    developmental process 6931
      anatomical structure development 6346
        multicellular organism development 5773
          system development 5413
            immune system development 1113
              hematopoietic or lymphoid organ development 1046
                hemopoiesis 994
                  leukocyte differentiation 621
                    mononuclear cell differentiation 480
                      lymphocyte differentiation 427
                        B cell differentiation 158
                          regulation of B cell differentiation 33
                            negative regulation of B cell differentiation 4
                              negative regulation of B-1 B cell differentiation 0
                              negative regulation of central B cell anergy 0
                              negative regulation of central B cell deletion 0
                              negative regulation of plasma cell differentiation 0
paths to the root