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ONTOLOGY REPORT - ANNOTATIONS


Term:myelin sheath
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Accession:GO:0043209 term browser browse the term
Definition:An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system.
Synonyms:narrow_synonym: Schwann cell myelin sheath;   astrocyte sheath;   oligodendrocyte myelin sheath
 xref: FMA:62983;   NIF_Subcellular:sao593830697;   Wikipedia:Myelin
 only_in_taxon: NCBITaxon:33208 ! Metazoa


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myelin sheath term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 located_in ISO PMID:17960831 UniProt PMID:17960831 RGD:10047364 NCBI chrNW_004624907:715,109...736,040
Ensembl chrNW_004624907:715,094...736,432
JBrowse link
G Bcl2 BCL2 apoptosis regulator located_in ISO (PMID:7953633) MGI PMID:7953633 NCBI chrNW_004624792:8,854,345...9,032,727
Ensembl chrNW_004624792:8,859,522...9,031,344
JBrowse link
G Ca13 carbonic anhydrase 13 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624744:6,418,487...6,447,023
Ensembl chrNW_004624744:6,416,664...6,447,315
JBrowse link
G Ca2 carbonic anhydrase 2 located_in ISO (PMID:14600151) MGI PMID:14600151 NCBI chrNW_004624744:6,168,030...6,183,407
Ensembl chrNW_004624744:6,167,606...6,183,538
JBrowse link
G Calm1 calmodulin 1 located_in IEA Ensembl
UniProt
GO_REF:0000107 GO_REF:0000117 NCBI chrNW_004624734:12,030,264...12,041,682
Ensembl chrNW_004624734:12,030,001...12,041,772
JBrowse link
G Calm2 calmodulin 2 located_in IEA Ensembl
UniProt
GO_REF:0000107 GO_REF:0000117 NCBI chrNW_004624738:28,525,290...28,541,562
Ensembl chrNW_004624738:28,525,285...28,541,514
JBrowse link
G Calm3 calmodulin 3 located_in IEA Ensembl
UniProt
GO_REF:0000107 GO_REF:0000117 NCBI chrNW_004624832:6,957,775...6,966,505
Ensembl chrNW_004624832:6,958,820...6,966,514
JBrowse link
G Clcn2 chloride voltage-gated channel 2 located_in ISO (PMID:22405205) UniProt PMID:22405205 NCBI chrNW_004624730:72,228,912...72,242,636
Ensembl chrNW_004624730:72,228,189...72,244,332
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase located_in ISO PMID:17960831
(PMID:24101522), (PMID:28251676)
UniProt
MGI
PMID:17960831 PMID:24101522 PMID:28251676 RGD:10047364 NCBI chrNW_004624795:1,856,455...1,861,142
Ensembl chrNW_004624795:1,855,992...1,861,053
JBrowse link
G Cntn2 contactin 2 located_in ISO (MGI:2675531|PMID:12963709) BHF-UCL PMID:12963709 MGI:2675531 NCBI chrNW_004624807:6,052,591...6,080,421
Ensembl chrNW_004624807:6,056,339...6,073,588
JBrowse link
G Dpysl2 dihydropyrimidinase like 2 located_in ISO PMID:17960831 UniProt PMID:17960831 RGD:10047364 NCBI chrNW_004624758:21,355,816...21,475,662
Ensembl chrNW_004624758:21,355,872...21,475,788
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 located_in ISO (PMID:15044753) MGI PMID:15044753 NCBI chrNW_004624795:3,373,313...3,391,509
Ensembl chrNW_004624795:3,373,000...3,391,602
JBrowse link
G Ermn ermin located_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624732:8,486,514...8,493,085
Ensembl chrNW_004624732:8,486,421...8,491,118
JBrowse link
G Gdi1 GDP dissociation inhibitor 1 located_in ISO PMID:17960831 UniProt PMID:17960831 RGD:10047364 NCBI chrNW_004624946:902,831...908,815
Ensembl chrNW_004624946:902,461...909,613
JBrowse link
G Gjc2 gap junction protein gamma 2 located_in ISO (PMID:20578039) MGI PMID:20578039 NCBI chrNW_004624937:898,876...905,247 JBrowse link
G Gjc3 gap junction protein gamma 3 located_in ISO (PMID:16481432) MGI PMID:16481432 NCBI chrNW_004624740:17,068,237...17,092,297 JBrowse link
G Glul glutamate-ammonia ligase located_in ISO PMID:17960831 UniProt PMID:17960831 RGD:10047364 NCBI chrNW_004624771:2,608,779...2,618,130 JBrowse link
G Gnao1 G protein subunit alpha o1 located_in ISO PMID:17960831 UniProt PMID:17960831 RGD:10047364 NCBI chrNW_004624757:178,616...346,443 JBrowse link
G Gsn gelsolin located_in ISO PMID:17960831 UniProt PMID:17960831 RGD:10047364 NCBI chrNW_004624760:13,943,680...14,004,660
Ensembl chrNW_004624760:13,943,888...13,969,905
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 located_in ISO PMID:17960831 UniProt PMID:17960831 RGD:10047364 NCBI chrNW_004624734:2,233,932...2,239,687
Ensembl chrNW_004624734:2,233,547...2,241,436
JBrowse link
G LOC101715424 tubulin alpha-1B chain-like located_in ISO PMID:17960831 UniProt PMID:17960831 RGD:10047364 NCBI chrNW_004624816:3,001,252...3,006,166 JBrowse link
G Mag myelin associated glycoprotein located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624794:8,237,005...8,251,933
Ensembl chrNW_004624794:8,236,223...8,258,361
JBrowse link
G Mbp myelin basic protein located_in IEA UniProt GO_REF:0000044 NCBI chrNW_004624806:3,465,881...3,587,428
Ensembl chrNW_004624806:3,489,681...3,588,335
JBrowse link
G Myo1d myosin ID located_in ISO PMID:17960831
(MGI:5607218|PMID:22284616)
UniProt PMID:17960831 PMID:22284616 MGI:5607218 RGD:10047364 NCBI chrNW_004624875:544,065...877,958
Ensembl chrNW_004624875:543,260...877,953
JBrowse link
G Pllp plasmolipin located_in ISO (PMID:26002055) UniProt PMID:26002055 NCBI chrNW_004624746:28,779,154...28,797,828
Ensembl chrNW_004624746:28,779,173...28,797,638
JBrowse link
G Plp1 proteolipid protein 1 located_in IEA UniProt
TreeGrafter
GO_REF:0000044 GO_REF:0000118 NCBI chrNW_004624954:135,065...150,911
Ensembl chrNW_004624954:133,105...150,953
JBrowse link
G Prxl2b peroxiredoxin like 2B located_in ISO (MGI:5545989|PMID:20950588) UniProt PMID:20950588 MGI:5545989 RGD:8554513 NCBI chrNW_004624818:7,478,680...7,485,431
Ensembl chrNW_004624818:7,483,001...7,485,431
JBrowse link
G Septin8 septin 8 located_in ISO PMID:17960831 UniProt PMID:17960831 RGD:10047364 NCBI chrNW_004624733:39,315,743...39,340,692 JBrowse link
G Serinc5 serine incorporator 5 located_in ISO (PMID:16405874) MGI PMID:16405874 NCBI chrNW_004624743:1,239,698...1,308,735
Ensembl chrNW_004624743:1,242,835...1,308,842
JBrowse link
G Sirt2 sirtuin 2 located_in IEA UniProt GO_REF:0000044 NCBI chrNW_004624794:12,239,363...12,259,561
Ensembl chrNW_004624794:12,235,263...12,259,276
JBrowse link
G Thy1 Thy-1 cell surface antigen located_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624784:14,779,533...14,784,315
Ensembl chrNW_004624784:14,780,698...14,784,897
JBrowse link
G Tspan2 tetraspanin 2 located_in ISO (PMID:24038504) MGI PMID:24038504 NCBI chrNW_004624772:10,750,539...10,806,868
Ensembl chrNW_004624772:10,750,539...10,806,300
JBrowse link
G Tubb4a tubulin beta 4A class IVa located_in ISO (PMID:16421295) MGI PMID:16421295 NCBI chrNW_004624828:3,588,001...3,594,294
Ensembl chrNW_004624828:3,584,848...3,594,294
JBrowse link
compact myelin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mag myelin associated glycoprotein located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624794:8,237,005...8,251,933
Ensembl chrNW_004624794:8,236,223...8,258,361
JBrowse link
G Mbp myelin basic protein located_in ISO (PMID:12718855)
MMO:0000679
RGD
MGI
PMID:2462020 PMID:10537049 PMID:12718855 RGD:1358774 RGD:633193 NCBI chrNW_004624806:3,465,881...3,587,428
Ensembl chrNW_004624806:3,489,681...3,588,335
JBrowse link
G Pllp plasmolipin ISO RGD PMID:12871592 RGD:1358791 NCBI chrNW_004624746:28,779,154...28,797,828
Ensembl chrNW_004624746:28,779,173...28,797,638
JBrowse link
G Pmp22 peripheral myelin protein 22 located_in ISO (PMID:11114256), (PMID:29315582) RGD
MGI
PMID:1556154 PMID:11114256 PMID:29315582 RGD:1358785 NCBI chrNW_004624877:3,293,980...3,328,337
Ensembl chrNW_004624877:3,292,244...3,328,660
JBrowse link
lateral loop term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdh1 cadherin 1 located_in ISO (MGI:4441217|PMID:20237282) BHF-UCL PMID:20237282 MGI:4441217 NCBI chrNW_004624746:17,480,472...17,557,722
Ensembl chrNW_004624746:17,483,469...17,557,581
JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 located_in ISO (MGI:4441217|PMID:20237282) BHF-UCL PMID:20237282 MGI:4441217 NCBI chrNW_004624730:62,001,547...62,223,098
Ensembl chrNW_004624730:62,002,280...62,223,319
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO RGD PMID:15800203 RGD:1582139 NCBI chrNW_004624795:3,373,313...3,391,509
Ensembl chrNW_004624795:3,373,000...3,391,602
JBrowse link
G Pals1 protein associated with LIN7 1, MAGUK p55 family member located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624734:33,659,625...33,758,680
Ensembl chrNW_004624734:33,658,975...33,721,548
JBrowse link
G Pard3 par-3 family cell polarity regulator located_in ISO (MGI:4441217|PMID:20237282) BHF-UCL PMID:20237282 MGI:4441217 NCBI chrNW_004624805:7,204,915...7,810,050
Ensembl chrNW_004624805:7,205,092...7,808,542
JBrowse link
G Sirt2 sirtuin 2 located_in ISO PMID:21949390 UniProt PMID:21949390 RGD:8655533 NCBI chrNW_004624794:12,239,363...12,259,561
Ensembl chrNW_004624794:12,235,263...12,259,276
JBrowse link
G Stx4 syntaxin 4 located_in ISO (MGI:4441217|PMID:20237282) BHF-UCL PMID:20237282 MGI:4441217 NCBI chrNW_004624782:14,094,727...14,101,210
Ensembl chrNW_004624782:14,090,850...14,105,058
JBrowse link
myelin sheath abaxonal region term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase ISO RGD PMID:16051705 RGD:6483360 NCBI chrNW_004624795:1,856,455...1,861,142
Ensembl chrNW_004624795:1,855,992...1,861,053
JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 located_in ISO (MGI:4441217|PMID:20237282) BHF-UCL PMID:20237282 MGI:4441217 NCBI chrNW_004624730:62,001,547...62,223,098
Ensembl chrNW_004624730:62,002,280...62,223,319
JBrowse link
G Exoc4 exocyst complex component 4 located_in ISO (MGI:4441217|PMID:20237282) BHF-UCL PMID:20237282 MGI:4441217 NCBI chrNW_004624783:2,315,128...3,165,343
Ensembl chrNW_004624783:2,316,300...3,165,255
JBrowse link
G Itgb1 integrin subunit beta 1 located_in ISO (MGI:4441217|PMID:20237282) BHF-UCL PMID:20237282 MGI:4441217 NCBI chrNW_004624805:8,748,848...8,800,259
Ensembl chrNW_004624805:8,765,949...8,802,149
JBrowse link
G Llgl1 LLGL scribble cell polarity complex component 1 located_in ISO (MGI:4441217|PMID:20237282) BHF-UCL PMID:20237282 MGI:4441217 NCBI chrNW_004624849:3,227,518...3,245,137
Ensembl chrNW_004624849:3,227,758...3,245,118
JBrowse link
G Myoc myocilin ISO RGD PMID:12838505 RGD:1600847 NCBI chrNW_004624771:10,066,170...10,080,257
Ensembl chrNW_004624771:10,065,788...10,080,680
JBrowse link
G Prkcz protein kinase C zeta located_in ISO (MGI:4441217|PMID:20237282) BHF-UCL PMID:20237282 MGI:4441217 NCBI chrNW_004624818:7,758,192...7,846,950
Ensembl chrNW_004624818:7,759,770...7,847,208
JBrowse link
G Scrib scribble planar cell polarity protein located_in ISO (MGI:4441217|PMID:20237282) BHF-UCL PMID:20237282 MGI:4441217 NCBI chrNW_004624735:12,997,358...13,018,765
Ensembl chrNW_004624735:12,997,408...13,018,533
JBrowse link
G Sirt2 sirtuin 2 ISO RGD PMID:17344398 RGD:8553877 NCBI chrNW_004624794:12,239,363...12,259,561
Ensembl chrNW_004624794:12,235,263...12,259,276
JBrowse link
myelin sheath adaxonal region term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 located_in ISO (MGI:4441217|PMID:20237282) BHF-UCL PMID:20237282 MGI:4441217 NCBI chrNW_004624781:11,781,893...11,820,440
Ensembl chrNW_004624781:11,781,886...11,821,816
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase ISO RGD PMID:16051705 RGD:6483360 NCBI chrNW_004624795:1,856,455...1,861,142
Ensembl chrNW_004624795:1,855,992...1,861,053
JBrowse link
G Mag myelin associated glycoprotein located_in ISO
IEA
RGD
Ensembl
PMID:375239 GO_REF:0000107 RGD:9685298 NCBI chrNW_004624794:8,237,005...8,251,933
Ensembl chrNW_004624794:8,236,223...8,258,361
JBrowse link
G Pals1 protein associated with LIN7 1, MAGUK p55 family member located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624734:33,659,625...33,758,680
Ensembl chrNW_004624734:33,658,975...33,721,548
JBrowse link
G Pten phosphatase and tensin homolog located_in ISO (MGI:4441217|PMID:20237282) BHF-UCL PMID:20237282 MGI:4441217 NCBI chrNW_004624791:13,975,235...14,056,900 JBrowse link
G Stx4 syntaxin 4 located_in ISO (MGI:4441217|PMID:20237282) BHF-UCL PMID:20237282 MGI:4441217 NCBI chrNW_004624782:14,094,727...14,101,210
Ensembl chrNW_004624782:14,090,850...14,105,058
JBrowse link
Schmidt-Lanterman incisure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 located_in ISO (MGI:4441217|PMID:20237282) BHF-UCL PMID:20237282 MGI:4441217 NCBI chrNW_004624781:11,781,893...11,820,440
Ensembl chrNW_004624781:11,781,886...11,821,816
JBrowse link
G Cdh1 cadherin 1 located_in ISO (MGI:4441217|PMID:20237282) BHF-UCL PMID:20237282 MGI:4441217 NCBI chrNW_004624746:17,480,472...17,557,722
Ensembl chrNW_004624746:17,483,469...17,557,581
JBrowse link
G Cldn19 claudin 19 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624892:1,974,608...1,982,042
Ensembl chrNW_004624892:1,974,534...1,982,114
JBrowse link
G Cldn5 claudin 5 ISO RGD PMID:12403818 RGD:634852 NCBI chrNW_004624747:164,113...166,502
Ensembl chrNW_004624747:164,761...165,417
JBrowse link
G Jam3 junctional adhesion molecule 3 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624812:8,644,002...8,707,257
Ensembl chrNW_004624812:8,643,921...8,707,351
JBrowse link
G Mag myelin associated glycoprotein located_in ISO
IEA
RGD
Ensembl
PMID:12838505 GO_REF:0000107 RGD:1600847 NCBI chrNW_004624794:8,237,005...8,251,933
Ensembl chrNW_004624794:8,236,223...8,258,361
JBrowse link
G Mal mal, T cell differentiation protein ISO RGD PMID:12153479 RGD:625622 NCBI chrNW_004624749:1,854,177...1,877,054
Ensembl chrNW_004624749:1,853,838...1,879,590
JBrowse link
G Marveld2 MARVEL domain containing 2 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624905:277,718...300,821
Ensembl chrNW_004624905:284,356...297,865
JBrowse link
G Mpdz multiple PDZ domain crumbs cell polarity complex component located_in ISO (MGI:4441217|PMID:20237282) BHF-UCL PMID:20237282 MGI:4441217 NCBI chrNW_004624736:17,392,132...17,555,612
Ensembl chrNW_004624736:17,397,405...17,533,674
JBrowse link
G Myoc myocilin ISO RGD PMID:12838505 RGD:1600847 NCBI chrNW_004624771:10,066,170...10,080,257
Ensembl chrNW_004624771:10,065,788...10,080,680
JBrowse link
G Ncmap non-compact myelin associated protein located_in IEA InterPro
TreeGrafter
GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624764:8,947,138...8,983,740
Ensembl chrNW_004624764:8,947,155...8,983,717
JBrowse link
G Pals1 protein associated with LIN7 1, MAGUK p55 family member located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624734:33,659,625...33,758,680
Ensembl chrNW_004624734:33,658,975...33,721,548
JBrowse link
G Pard3 par-3 family cell polarity regulator located_in ISO (MGI:4441217|PMID:20237282) BHF-UCL PMID:20237282 MGI:4441217 NCBI chrNW_004624805:7,204,915...7,810,050
Ensembl chrNW_004624805:7,205,092...7,808,542
JBrowse link
G Prkci protein kinase C iota located_in ISO (MGI:4441217|PMID:20237282) BHF-UCL PMID:20237282 MGI:4441217 NCBI chrNW_004624730:48,258,524...48,340,217 JBrowse link
G Pten phosphatase and tensin homolog located_in ISO (MGI:4441217|PMID:20237282) BHF-UCL PMID:20237282 MGI:4441217 NCBI chrNW_004624791:13,975,235...14,056,900 JBrowse link
G Sirt2 sirtuin 2 located_in ISO (MGI:5567913|PMID:16933150)
PMID:21949390
UniProt PMID:16933150 PMID:21949390 MGI:5567913 RGD:8655533 NCBI chrNW_004624794:12,239,363...12,259,561
Ensembl chrNW_004624794:12,235,263...12,259,276
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 15756
    cellular anatomical entity 15656
      myelin sheath 55
        compact myelin + 19
        lateral loop 7
        myelin sheath abaxonal region 9
        myelin sheath adaxonal region 6
paths to the root