Septin8 (septin 8) - Rat Genome Database

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Gene: Septin8 (septin 8) Heterocephalus glaber
Analyze
Symbol: Septin8
Name: septin 8
RGD ID: 18921169
Description: ENCODES a protein that exhibits SNARE binding (ortholog); INVOLVED IN regulation of intracellular protein transport (ortholog); regulation of protein stability (ortholog); regulation of SNARE complex assembly (ortholog); ASSOCIATED WITH familial adenomatous polyposis 1 (ortholog); Hereditary Neoplastic Syndromes (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN myelin sheath (ortholog); presynapse (ortholog); septin complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Sept8; septin-8
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473339,315,743 - 39,340,692 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Septin8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473339,315,743 - 39,340,692 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SEPTIN8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385132,750,819 - 132,780,083 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5132,750,819 - 132,807,241 (-)EnsemblGRCh38hg38GRCh38
GRCh375132,086,511 - 132,113,704 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365132,114,408 - 132,141,460 (-)NCBINCBI36Build 36hg18NCBI36
Build 345132,119,595 - 132,140,966NCBI
Celera5128,216,608 - 128,243,585 (-)NCBICelera
Cytogenetic Map5q31.1NCBI
HuRef5127,279,118 - 127,306,224 (-)NCBIHuRef
CHM1_15131,519,780 - 131,546,835 (-)NCBICHM1_1
T2T-CHM13v2.05133,270,556 - 133,297,751 (-)NCBIT2T-CHM13v2.0
Septin8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391153,410,224 - 53,440,432 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1153,410,084 - 53,440,392 (+)EnsemblGRCm39 Ensembl
GRCm381153,519,397 - 53,549,605 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1153,519,257 - 53,549,565 (+)EnsemblGRCm38mm10GRCm38
MGSCv371153,333,302 - 53,357,598 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361153,363,223 - 53,387,519 (+)NCBIMGSCv36mm8
Celera1158,099,719 - 58,123,580 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1131.96NCBI
Septin8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81038,185,454 - 38,214,502 (+)NCBIGRCr8
mRatBN7.21037,684,649 - 37,713,704 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1037,684,639 - 37,713,174 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1042,376,979 - 42,400,518 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01041,867,032 - 41,890,570 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01037,370,758 - 37,394,297 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01038,877,422 - 38,906,480 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1038,877,422 - 38,906,482 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01038,659,245 - 38,688,209 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41038,988,030 - 39,011,730 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11038,993,612 - 39,024,558 (+)NCBI
Celera1037,030,427 - 37,054,117 (+)NCBICelera
Cytogenetic Map10q22NCBI
Septin8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554084,126,745 - 4,144,064 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554084,129,302 - 4,143,683 (-)NCBIChiLan1.0ChiLan1.0
SEPTIN8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24128,062,946 - 128,090,496 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15126,202,510 - 126,229,552 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05128,167,699 - 128,194,750 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15134,327,735 - 134,355,677 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5134,327,735 - 134,355,677 (-)Ensemblpanpan1.1panPan2
SEPTIN8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11121,052,833 - 21,078,721 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1121,054,025 - 21,113,608 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1119,854,451 - 19,880,893 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01121,838,844 - 21,865,301 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1121,835,529 - 21,864,799 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11120,557,313 - 20,583,758 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01120,405,017 - 20,431,448 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01121,047,382 - 21,073,891 (-)NCBIUU_Cfam_GSD_1.0
Septin8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213115,421,662 - 115,447,110 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366472,424,371 - 2,451,197 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366472,424,029 - 2,450,459 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEPTIN8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2135,077,170 - 135,104,471 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12135,077,158 - 135,104,484 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22140,545,457 - 140,572,862 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SEPTIN8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12335,567,687 - 35,595,051 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2335,567,347 - 35,594,588 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603442,347,419 - 42,374,731 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_004836600   ⟹   XP_004836657
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473339,316,206 - 39,340,692 (+)NCBI
RefSeq Acc Id: XM_004836601   ⟹   XP_004836658
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473339,316,206 - 39,340,692 (+)NCBI
RefSeq Acc Id: XM_004836604   ⟹   XP_004836661
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473339,316,206 - 39,335,867 (+)NCBI
RefSeq Acc Id: XM_004836605   ⟹   XP_004836662
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473339,316,206 - 39,335,867 (+)NCBI
RefSeq Acc Id: XM_004836606   ⟹   XP_004836663
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473339,316,206 - 39,335,867 (+)NCBI
RefSeq Acc Id: XM_013078976   ⟹   XP_012934430
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473339,316,206 - 39,340,692 (+)NCBI
RefSeq Acc Id: XM_013078981   ⟹   XP_012934435
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473339,316,206 - 39,335,867 (+)NCBI
RefSeq Acc Id: XM_021241430   ⟹   XP_021097089
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473339,315,743 - 39,340,692 (+)NCBI
RefSeq Acc Id: XP_021097089   ⟸   XM_021241430
- Peptide Label: isoform X4
- UniProtKB: A0A0P6K5G7 (UniProtKB/TrEMBL),   A0AAX6RKZ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004836657   ⟸   XM_004836600
- Peptide Label: isoform X1
- UniProtKB: A0A0P6K5G7 (UniProtKB/TrEMBL),   A0AAX6NTR3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012934430   ⟸   XM_013078976
- Peptide Label: isoform X2
- UniProtKB: A0A0P6K5G7 (UniProtKB/TrEMBL),   A0AAX6R6I0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004836658   ⟸   XM_004836601
- Peptide Label: isoform X3
- UniProtKB: A0A0P6K5G7 (UniProtKB/TrEMBL),   A0AAX6NTM0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004836662   ⟸   XM_004836605
- Peptide Label: isoform X7
- UniProtKB: A0A0P6K5G7 (UniProtKB/TrEMBL),   A0AAX6NTL5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004836663   ⟸   XM_004836606
- Peptide Label: isoform X8
- UniProtKB: A0A0P6K5G7 (UniProtKB/TrEMBL),   A0AAX6NTM8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004836661   ⟸   XM_004836604
- Peptide Label: isoform X5
- UniProtKB: A0A0P6K5G7 (UniProtKB/TrEMBL),   A0AAX6NTL9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012934435   ⟸   XM_013078981
- Peptide Label: isoform X6
- UniProtKB: A0A0P6K5G7 (UniProtKB/TrEMBL),   A0AAX6R6V9 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000007976 ENTREZGENE
Ensembl Transcript ENSHGLT00000011238 ENTREZGENE
  ENSHGLT00000011239 ENTREZGENE
  ENSHGLT00000011240 ENTREZGENE
  ENSHGLT00000011241 ENTREZGENE
Gene3D-CATH P-loop containing nucleotide triphosphate hydrolases UniProtKB/TrEMBL
InterPro G_SEPTIN_dom UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Septin UniProtKB/TrEMBL
NCBI Gene Septin8 ENTREZGENE
PANTHER SEPTIN UniProtKB/TrEMBL
  SEPTIN-8 UniProtKB/TrEMBL
Pfam Septin UniProtKB/TrEMBL
PIRSF Septin UniProtKB/TrEMBL
PROSITE G_SEPTIN UniProtKB/TrEMBL
Superfamily-SCOP P-loop containing nucleoside triphosphate hydrolases UniProtKB/TrEMBL
UniProt A0A0P6K5G7 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6NTL5 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6NTL9 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6NTM0 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6NTM8 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6NTR3 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6R6I0 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6R6V9 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RKZ5 ENTREZGENE, UniProtKB/TrEMBL