Mal (mal, T cell differentiation protein) - Rat Genome Database

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Gene: Mal (mal, T cell differentiation protein) Heterocephalus glaber
Analyze
Symbol: Mal
Name: mal, T cell differentiation protein
RGD ID: 18900312
Description: ENCODES a protein that exhibits structural constituent of myelin sheath (ortholog); INVOLVED IN central nervous system myelination (ortholog); myelination (ortholog); positive regulation of extrinsic apoptotic signaling pathway via death domain receptors (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); genetic disease (ortholog); Head and Neck Neoplasms (ortholog); FOUND IN apical plasma membrane (ortholog); endoplasmic reticulum (ortholog); hinge region between urothelial plaques of apical plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Myelin and lymphocyte protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247491,853,838 - 1,879,590 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247491,854,177 - 1,877,054 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Mal
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247491,853,838 - 1,879,590 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247491,854,177 - 1,877,054 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
MAL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38295,025,708 - 95,053,992 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl295,025,677 - 95,053,992 (+)EnsemblGRCh38hg38GRCh38
GRCh37295,691,453 - 95,719,737 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36295,055,206 - 95,083,462 (+)NCBINCBI36Build 36hg18NCBI36
Build 34295,113,352 - 95,141,609NCBI
Celera290,041,551 - 90,070,642 (+)NCBICelera
Cytogenetic Map2q11.1ENTREZGENE
HuRef289,720,233 - 89,748,565 (+)NCBIHuRef
CHM1_1295,695,693 - 95,724,010 (+)NCBICHM1_1
T2T-CHM13v2.0295,532,209 - 95,560,493 (+)NCBIT2T-CHM13v2.0
Mal
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392127,475,146 - 127,498,615 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2127,475,146 - 127,498,615 (-)EnsemblGRCm39 Ensembl
GRCm382127,633,226 - 127,656,695 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2127,633,226 - 127,656,695 (-)EnsemblGRCm38mm10GRCm38
MGSCv372127,458,962 - 127,482,431 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362127,324,671 - 127,347,724 (-)NCBIMGSCv36mm8
Celera2128,878,634 - 128,902,174 (-)NCBICelera
Cytogenetic Map2F1NCBI
cM Map262.06NCBI
Mal
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83135,317,664 - 135,341,423 (-)NCBIGRCr8
mRatBN7.23114,864,378 - 114,888,136 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3114,864,378 - 114,888,136 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3118,753,666 - 118,777,409 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03127,349,206 - 127,372,951 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03125,009,582 - 125,033,317 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03120,209,647 - 120,233,655 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3120,209,647 - 120,233,655 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03127,099,278 - 127,123,286 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43115,166,671 - 115,190,432 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13115,072,243 - 115,096,005 (-)NCBI
Celera3113,699,325 - 113,723,029 (-)NCBICelera
RH 3.4 Map3998.6RGD
Cytogenetic Map3q36NCBI
Mal
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554703,372,577 - 3,398,836 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554703,372,577 - 3,396,868 (+)NCBIChiLan1.0ChiLan1.0
MAL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21233,243,632 - 33,271,455 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A33,246,391 - 33,274,217 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A104,355,020 - 104,382,849 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A95,930,298 - 95,956,573 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A95,930,315 - 95,956,573 (+)Ensemblpanpan1.1panPan2
MAL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11734,977,298 - 35,000,690 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1734,977,298 - 35,001,349 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1734,746,124 - 34,769,084 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01735,748,374 - 35,771,352 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1735,748,374 - 35,772,227 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11734,876,424 - 34,899,422 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01734,945,386 - 34,968,323 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01735,154,731 - 35,177,728 (-)NCBIUU_Cfam_GSD_1.0
Mal
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440507383,398 - 89,966 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493718563,274 - 68,187 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493718562,807 - 68,205 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl346,181,555 - 46,242,047 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1346,223,610 - 46,242,306 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2348,182,689 - 48,200,460 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MAL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11466,521 - 92,476 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1466,610 - 93,588 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041167,449,824 - 167,476,696 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000022943   ⟹   ENSHGLP00000022729
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247491,853,838 - 1,879,590 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000022944   ⟹   ENSHGLP00000022730
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247491,854,296 - 1,876,553 (+)Ensembl
RefSeq Acc Id: XM_004844335   ⟹   XP_004844392
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247491,854,177 - 1,877,054 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004844392 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHA99040 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000022729
GenBank Protein JAN96624 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004844392   ⟸   XM_004844335
- UniProtKB: G5APT0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000022730   ⟸   ENSHGLT00000022944
RefSeq Acc Id: ENSHGLP00000022729   ⟸   ENSHGLT00000022943


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000016213 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000022943 ENTREZGENE
InterPro MAL UniProtKB/TrEMBL
  Marvel UniProtKB/TrEMBL
KEGG Report hgl:101696352 UniProtKB/TrEMBL
NCBI Gene Mal ENTREZGENE
PANTHER MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN UniProtKB/TrEMBL
  MYELIN AND LYMPHOCYTE PROTEIN UniProtKB/TrEMBL
Pfam MARVEL UniProtKB/TrEMBL
PRINTS MALPROTEIN UniProtKB/TrEMBL
PROSITE MARVEL UniProtKB/TrEMBL
UniProt G5APT0 ENTREZGENE, UniProtKB/TrEMBL