Mpdz (multiple PDZ domain crumbs cell polarity complex component) - Rat Genome Database

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Gene: Mpdz (multiple PDZ domain crumbs cell polarity complex component) Heterocephalus glaber
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Symbol: Mpdz
Name: multiple PDZ domain crumbs cell polarity complex component
RGD ID: 18905389
Description: INVOLVED IN cell adhesion (ortholog); dendrite development (ortholog); intracellular protein transport (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); Congenital Hydrocephalus 2, with or without Brain or Eye Anomalies (ortholog); genetic disease (ortholog); FOUND IN apical plasma membrane (ortholog); apicolateral plasma membrane (ortholog); cytoplasmic vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: multiple PDZ domain protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473617,397,405 - 17,533,674 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473617,392,132 - 17,555,612 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074  


Genomics

Comparative Map Data
Mpdz
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473617,397,405 - 17,533,674 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473617,392,132 - 17,555,612 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
MPDZ
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38913,105,707 - 13,279,692 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl913,105,706 - 13,279,692 (-)EnsemblGRCh38hg38GRCh38
GRCh37913,105,706 - 13,279,691 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36913,095,703 - 13,240,365 (-)NCBINCBI36Build 36hg18NCBI36
Build 34913,096,575 - 13,240,357NCBI
Celera913,038,280 - 13,183,037 (-)NCBICelera
Cytogenetic Map9p23NCBI
HuRef913,069,879 - 13,214,632 (-)NCBIHuRef
CHM1_1913,105,992 - 13,279,791 (-)NCBICHM1_1
T2T-CHM13v2.0913,115,022 - 13,289,091 (-)NCBIT2T-CHM13v2.0
Mpdz
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39481,196,736 - 81,361,112 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl481,196,742 - 81,361,052 (-)EnsemblGRCm39 Ensembl
GRCm38481,278,499 - 81,442,897 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl481,278,500 - 81,442,815 (-)EnsemblGRCm38mm10GRCm38
MGSCv37480,924,404 - 81,088,709 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36480,750,824 - 80,913,903 (-)NCBIMGSCv36mm8
Celera479,839,558 - 79,997,048 (-)NCBICelera
Cytogenetic Map4C3NCBI
cM Map438.0NCBI
Mpdz
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85100,812,121 - 100,966,566 (-)NCBIGRCr8
mRatBN7.2595,766,112 - 95,920,531 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl595,766,118 - 95,920,499 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx598,137,388 - 98,291,673 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0599,947,068 - 100,102,219 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0599,948,242 - 100,102,527 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0599,413,184 - 99,566,356 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl599,413,187 - 99,566,318 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05103,442,806 - 103,596,600 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45100,008,984 - 100,170,202 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15100,014,212 - 100,175,428 (-)NCBI
Celera594,336,315 - 94,488,569 (-)NCBICelera
Cytogenetic Map5q31NCBI
Mpdz
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543416,284,123 - 16,418,092 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543416,284,123 - 16,431,853 (-)NCBIChiLan1.0ChiLan1.0
MPDZ
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v211111,253,670 - 111,430,166 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan19111,259,645 - 111,436,524 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0912,943,252 - 13,120,126 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1913,390,642 - 13,564,246 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl913,391,903 - 13,535,292 (-)Ensemblpanpan1.1panPan2
MPDZ
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11133,691,434 - 33,826,500 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1133,692,296 - 33,826,437 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1132,400,323 - 32,561,595 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01134,595,030 - 34,756,348 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1134,595,575 - 34,756,388 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11133,300,994 - 33,462,185 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01133,086,512 - 33,254,154 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01133,749,245 - 33,910,664 (-)NCBIUU_Cfam_GSD_1.0
Mpdz
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947148,481,482 - 148,631,516 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365396,932,473 - 7,084,227 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365396,934,180 - 7,084,117 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MPDZ
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1209,181,467 - 209,349,297 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11209,181,441 - 209,351,797 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21233,122,084 - 233,215,771 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MPDZ
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11266,275,725 - 66,450,398 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1266,304,514 - 66,449,110 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603854,508,794 - 54,683,624 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004838295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004838296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013069731 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013069734 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013069739 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021252850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021252851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021252852 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021252853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021252854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021252855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021252856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01012785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01012786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01012787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GEBF01006102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JH166319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSHGLT00000023368   ⟹   ENSHGLP00000023153
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473617,397,405 - 17,533,674 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000023369   ⟹   ENSHGLP00000023154
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473617,397,405 - 17,461,878 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000023370   ⟹   ENSHGLP00000023155
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473617,397,405 - 17,420,468 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000023371   ⟹   ENSHGLP00000023156
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473617,446,605 - 17,458,737 (-)Ensembl
RefSeq Acc Id: XM_004838295   ⟹   XP_004838352
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473617,392,132 - 17,555,611 (-)NCBI
RefSeq Acc Id: XM_004838296   ⟹   XP_004838353
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473617,392,132 - 17,555,611 (-)NCBI
RefSeq Acc Id: XM_013069731   ⟹   XP_012925185
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473617,392,132 - 17,555,611 (-)NCBI
RefSeq Acc Id: XM_013069734   ⟹   XP_012925188
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473617,392,132 - 17,555,611 (-)NCBI
RefSeq Acc Id: XM_013069739   ⟹   XP_012925193
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473617,392,132 - 17,555,611 (-)NCBI
RefSeq Acc Id: XM_021252850   ⟹   XP_021108509
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473617,392,132 - 17,555,611 (-)NCBI
RefSeq Acc Id: XM_021252851   ⟹   XP_021108510
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473617,392,132 - 17,555,611 (-)NCBI
RefSeq Acc Id: XM_021252852   ⟹   XP_021108511
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473617,392,132 - 17,555,611 (-)NCBI
RefSeq Acc Id: XM_021252853   ⟹   XP_021108512
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473617,392,132 - 17,555,611 (-)NCBI
RefSeq Acc Id: XM_021252854   ⟹   XP_021108513
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473617,392,132 - 17,555,611 (-)NCBI
RefSeq Acc Id: XM_021252855   ⟹   XP_021108514
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473617,392,132 - 17,555,611 (-)NCBI
RefSeq Acc Id: XM_021252856   ⟹   XP_021108515
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473617,405,853 - 17,555,612 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021108513   ⟸   XM_021252854
- Peptide Label: isoform X7
- UniProtKB: G5AP53 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021108512   ⟸   XM_021252853
- Peptide Label: isoform X6
- UniProtKB: G5AP53 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004838353   ⟸   XM_004838296
- Peptide Label: isoform X10
- UniProtKB: A0A0P6J4R8 (UniProtKB/TrEMBL),   G5AP53 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021108514   ⟸   XM_021252855
- Peptide Label: isoform X8
- UniProtKB: G5AP53 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004838352   ⟸   XM_004838295
- Peptide Label: isoform X5
- UniProtKB: G5AP53 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021108511   ⟸   XM_021252852
- Peptide Label: isoform X3
- UniProtKB: G5AP53 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012925193   ⟸   XM_013069739
- Peptide Label: isoform X12
- UniProtKB: G5AP53 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012925188   ⟸   XM_013069734
- Peptide Label: isoform X9
- UniProtKB: G5AP53 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012925185   ⟸   XM_013069731
- Peptide Label: isoform X4
- UniProtKB: G5AP53 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021108510   ⟸   XM_021252851
- Peptide Label: isoform X2
- UniProtKB: G5AP53 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021108509   ⟸   XM_021252850
- Peptide Label: isoform X1
- UniProtKB: G5AP53 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021108515   ⟸   XM_021252856
- Peptide Label: isoform X11
- UniProtKB: G5AP53 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000023156   ⟸   ENSHGLT00000023371
RefSeq Acc Id: ENSHGLP00000023155   ⟸   ENSHGLT00000023370
RefSeq Acc Id: ENSHGLP00000023154   ⟸   ENSHGLT00000023369
RefSeq Acc Id: ENSHGLP00000023153   ⟸   ENSHGLT00000023368


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000016510 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000023368 ENTREZGENE
Gene3D-CATH 2.30.42.10 UniProtKB/TrEMBL
  L27 domain UniProtKB/TrEMBL
InterPro L27_2 UniProtKB/TrEMBL
  L27_dom UniProtKB/TrEMBL
  L27_dom_sf UniProtKB/TrEMBL
  MPDZ UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
NCBI Gene Mpdz ENTREZGENE
PANTHER MULTIPLE PDZ DOMAIN PROTEIN UniProtKB/TrEMBL
  MULTIPLE PDZ DOMAIN PROTEIN UniProtKB/TrEMBL
  PATJ HOMOLOG UniProtKB/TrEMBL
Pfam L27_2 UniProtKB/TrEMBL
  MPDZ_u10 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
PROSITE L27 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
SMART PDZ UniProtKB/TrEMBL
Superfamily-SCOP SSF101288 UniProtKB/TrEMBL
  SSF50156 UniProtKB/TrEMBL
UniProt A0A0P6J4R8 ENTREZGENE, UniProtKB/TrEMBL
  G5AP53 ENTREZGENE, UniProtKB/TrEMBL