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ONTOLOGY REPORT - ANNOTATIONS


Term:tRNA aminoacylation
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Accession:GO:0043039 term browser browse the term
Definition:The chemical reactions and pathways by which the various amino acids become bonded to their corresponding tRNAs. The most common route for synthesis of aminoacyl tRNA is by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules.
Synonyms:exact_synonym: aminoacyl-tRNA biosynthesis;   aminoacyl-tRNA biosynthetic process;   tRNA charging


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tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DARS2 aspartyl-tRNA synthetase 2, mitochondrial involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:55,334,669...55,367,257
Ensembl chr25:55,332,340...55,367,248
JBrowse link
G FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro GO_REF:0000002 NCBI chr17:66,356,479...66,921,276
Ensembl chr17:66,543,452...66,898,446
JBrowse link
G LOC103228400 tyrosine--tRNA ligase, mitochondrial-like involved_in IEA TreeGrafter
Ensembl
GO_REF:0000107 GO_REF:0000118 NCBI chr22:74,734,656...74,736,422 JBrowse link
G YARS2 tyrosyl-tRNA synthetase 2 involved_in IEA TreeGrafter
Ensembl
GO_REF:0000107 GO_REF:0000118 NCBI chr11:32,181,214...32,192,654
Ensembl chr11:32,181,397...32,192,454
JBrowse link
alanyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AARS1 alanyl-tRNA synthetase 1 involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:16906134) RGD
Ensembl
TreeGrafter
MGI
InterPro
PMID:2040280 PMID:16906134 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:2302982 NCBI chr 5:53,399,717...53,433,472
Ensembl chr 5:53,395,638...53,433,461
JBrowse link
G AARS2 alanyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro
TreeGrafter
GO_REF:0000002 GO_REF:0000118 NCBI chr17:27,855,688...27,869,427
Ensembl chr17:27,855,713...27,870,409
JBrowse link
G LOC103243378 alanyl-tRNA editing protein Aarsd1 involved_in IEA InterPro GO_REF:0000002 NCBI chr16:63,323,110...63,337,167
Ensembl chr16:63,322,885...63,339,596
JBrowse link
arginyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DALRD3 DALR anticodon binding domain containing 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr22:10,415,833...10,419,492
Ensembl chr22:10,411,353...10,419,770
JBrowse link
G RARS1 arginyl-tRNA synthetase 1 involved_in ISO
IEA
RGD
Ensembl
TreeGrafter
InterPro
PMID:7082655 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:2303394 NCBI chr23:70,711,435...70,746,000
Ensembl chr23:70,711,016...70,745,884
JBrowse link
G RARS2 arginyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro
TreeGrafter
GO_REF:0000002 GO_REF:0000118 NCBI chr13:11,995,422...12,068,150
Ensembl chr13:11,995,453...12,068,138
JBrowse link
asparaginyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NARS1 asparaginyl-tRNA synthetase 1 involved_in IEA InterPro
TreeGrafter
Ensembl
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr18:22,107,287...22,129,378
Ensembl chr18:22,107,291...22,131,140
JBrowse link
G NARS2 asparaginyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro
TreeGrafter
GO_REF:0000002 GO_REF:0000118 NCBI chr 1:69,647,713...69,778,390
Ensembl chr 1:69,643,531...69,778,361
JBrowse link
aspartyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DARS1 aspartyl-tRNA synthetase 1 involved_in IEA InterPro
TreeGrafter
GO_REF:0000002 GO_REF:0000118 NCBI chr10:20,120,999...20,202,019
Ensembl chr10:20,119,914...20,201,991
JBrowse link
G DARS2 aspartyl-tRNA synthetase 2, mitochondrial involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr25:55,334,669...55,367,257
Ensembl chr25:55,332,340...55,367,248
JBrowse link
cysteinyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARS1 cysteinyl-tRNA synthetase 1 involved_in IEA Ensembl
TreeGrafter
InterPro
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:2,812,169...2,871,835
Ensembl chr 1:2,812,016...2,871,800
JBrowse link
G CARS2 cysteinyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro
Ensembl
TreeGrafter
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:88,871,338...88,929,454
Ensembl chr 3:88,871,460...88,929,436
JBrowse link
glutaminyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LARS1 leucyl-tRNA synthetase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:48,691,361...48,761,664
Ensembl chr23:48,677,622...48,761,596
JBrowse link
G QARS1 glutaminyl-tRNA synthetase 1 involved_in IEA InterPro
Ensembl
TreeGrafter
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr22:10,497,921...10,507,673
Ensembl chr22:10,497,658...10,507,325
JBrowse link
glutaminyl-tRNAGln biosynthesis via transamidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GATB glutamyl-tRNA amidotransferase subunit B involved_in IEA UniProt
TreeGrafter
Ensembl
GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:98,245,646...98,331,083
Ensembl chr 7:98,245,968...98,331,082
JBrowse link
G GATC glutamyl-tRNA amidotransferase subunit C involved_in IEA UniProt
TreeGrafter
Ensembl
GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr11:115,800,928...115,813,142
Ensembl chr11:115,800,949...115,812,555
JBrowse link
G QRSL1 glutaminyl-tRNA amidotransferase subunit QRSL1 involved_in IEA Ensembl
TreeGrafter
UniProt
GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr13:67,153,372...67,188,775
Ensembl chr13:67,151,437...67,189,662
JBrowse link
glutamyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EARS2 glutamyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro
TreeGrafter
Ensembl
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:21,248,866...21,282,725
Ensembl chr 5:21,251,224...21,282,966
JBrowse link
G EPRS1 glutamyl-prolyl-tRNA synthetase 1 involved_in IEA InterPro
Ensembl
GO_REF:0000002 GO_REF:0000107 NCBI chr25:9,534,747...9,618,119
Ensembl chr25:9,534,114...9,618,141
JBrowse link
glycyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GARS1 glycyl-tRNA synthetase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19470612) InterPro
Ensembl
MGI
PMID:19470612 GO_REF:0000002 GO_REF:0000107 NCBI chr21:27,750,532...27,791,143
Ensembl chr21:27,749,514...27,790,881
JBrowse link
histidyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HARS1 histidyl-tRNA synthetase 1 involved_in IEA Ensembl
TreeGrafter
InterPro
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr23:43,307,573...43,324,140
Ensembl chr23:43,307,415...43,323,767
JBrowse link
G HARS2 histidyl-tRNA synthetase 2, mitochondrial involved_in IEA Ensembl
TreeGrafter
InterPro
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr23:43,323,847...43,333,620
Ensembl chr23:43,323,892...43,331,401
JBrowse link
isoleucyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IARS1 isoleucyl-tRNA synthetase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:8052601) MGI
TreeGrafter
Ensembl
InterPro
PMID:8052601 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr12:102,745,155...102,819,638
Ensembl chr12:102,744,569...102,819,603
JBrowse link
G IARS2 isoleucyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro
TreeGrafter
GO_REF:0000002 GO_REF:0000118 NCBI chr25:9,414,316...9,485,542
Ensembl chr25:9,414,711...9,485,429
JBrowse link
leucyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LARS1 leucyl-tRNA synthetase 1 involved_in IEA InterPro
TreeGrafter
Ensembl
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr23:48,691,361...48,761,664
Ensembl chr23:48,677,622...48,761,596
JBrowse link
G LARS2 leucyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro
TreeGrafter
Ensembl
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr22:6,861,105...7,021,325
Ensembl chr22:6,861,006...7,020,009
JBrowse link
lysyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KARS1 lysyl-tRNA synthetase 1 involved_in ISO
IEA
RGD
TreeGrafter
InterPro
Ensembl
PMID:7082655 PMID:7372681 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:2303393 RGD:2303394 NCBI chr 5:61,113,215...61,133,093
Ensembl chr 5:61,113,213...61,132,995
JBrowse link
methionyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MARS1 methionyl-tRNA synthetase 1 involved_in IEA Ensembl
TreeGrafter
InterPro
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr11:53,397,380...53,410,596 JBrowse link
G MARS2 methionyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro
Ensembl
TreeGrafter
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr10:83,186,370...83,193,464
Ensembl chr10:83,187,344...83,189,125
JBrowse link
mitochondrial alanyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AARS2 alanyl-tRNA synthetase 2, mitochondrial involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:27,855,688...27,869,427
Ensembl chr17:27,855,713...27,870,409
JBrowse link
mitochondrial asparaginyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DARS2 aspartyl-tRNA synthetase 2, mitochondrial involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:55,334,669...55,367,257
Ensembl chr25:55,332,340...55,367,248
JBrowse link
mitochondrial glycyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GARS1 glycyl-tRNA synthetase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr21:27,750,532...27,791,143
Ensembl chr21:27,749,514...27,790,881
JBrowse link
mitochondrial tryptophanyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WARS2 tryptophanyl tRNA synthetase 2, mitochondrial involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:14,614,902...14,726,630
Ensembl chr20:14,615,349...14,726,780
JBrowse link
mitochondrial tyrosyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC103228400 tyrosine--tRNA ligase, mitochondrial-like involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:74,734,656...74,736,422 JBrowse link
G YARS2 tyrosyl-tRNA synthetase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:32,181,214...32,192,654
Ensembl chr11:32,181,397...32,192,454
JBrowse link
phenylalanyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial involved_in IEA TreeGrafter
Ensembl
GO_REF:0000107 GO_REF:0000118 NCBI chr17:66,356,479...66,921,276
Ensembl chr17:66,543,452...66,898,446
JBrowse link
G FARSA phenylalanyl-tRNA synthetase subunit alpha involved_in IEA Ensembl
TreeGrafter
InterPro
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:11,602,352...11,613,851
Ensembl chr 6:11,600,516...11,613,345
JBrowse link
G FARSB phenylalanyl-tRNA synthetase subunit beta involved_in IEA InterPro
Ensembl
TreeGrafter
UniProt
GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chr10:108,492,463...108,568,226
Ensembl chr10:108,492,652...108,568,293
JBrowse link
G LRRC47 leucine rich repeat containing 47 involved_in IEA InterPro GO_REF:0000002 NCBI chr20:127,881,446...127,896,138
Ensembl chr20:127,881,473...127,895,959
JBrowse link
prolyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPRS1 glutamyl-prolyl-tRNA synthetase 1 involved_in IEA InterPro
TreeGrafter
Ensembl
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr25:9,534,747...9,618,119
Ensembl chr25:9,534,114...9,618,141
JBrowse link
G PARS2 prolyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro
TreeGrafter
GO_REF:0000002 GO_REF:0000118 NCBI chr20:78,172,890...78,180,901
Ensembl chr20:78,178,634...78,180,061
JBrowse link
seryl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SARS1 seryl-tRNA synthetase 1 involved_in ISO (PMID:24095058), (PMID:36041817)
(PMID:28236339), (PMID:34570399)
UniProt PMID:24095058 PMID:28236339 PMID:34570399 PMID:36041817
G SARS2 seryl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro GO_REF:0000002 NCBI chr 6:33,536,160...33,552,160
Ensembl chr 6:33,536,498...33,552,000
JBrowse link
threonyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TARS1 threonyl-tRNA synthetase 1 involved_in IEA Ensembl
TreeGrafter
InterPro
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:32,670,020...32,697,608
Ensembl chr 4:32,670,203...32,699,168
JBrowse link
G TARS2 threonyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro
TreeGrafter
GO_REF:0000002 GO_REF:0000118
G TARS3 threonyl-tRNA synthetase 3 involved_in IEA InterPro
TreeGrafter
GO_REF:0000002 GO_REF:0000118 NCBI chr29:20,106,215...20,198,227
Ensembl chr29:20,105,747...20,185,159
JBrowse link
tRNA aminoacylation for mitochondrial protein translation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EARS2 glutamyl-tRNA synthetase 2, mitochondrial involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:21,248,866...21,282,725
Ensembl chr 5:21,251,224...21,282,966
JBrowse link
tRNA aminoacylation for protein translation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DARS2 aspartyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro GO_REF:0000002 NCBI chr25:55,334,669...55,367,257
Ensembl chr25:55,332,340...55,367,248
JBrowse link
G EPRS1 glutamyl-prolyl-tRNA synthetase 1 involved_in IEA UniProt GO_REF:0000117 NCBI chr25:9,534,747...9,618,119
Ensembl chr25:9,534,114...9,618,141
JBrowse link
G GARS1 glycyl-tRNA synthetase 1 involved_in IEA UniProt
Ensembl
GO_REF:0000107 GO_REF:0000117 NCBI chr21:27,750,532...27,791,143
Ensembl chr21:27,749,514...27,790,881
JBrowse link
G MARS1 methionyl-tRNA synthetase 1 involved_in IEA UniProt GO_REF:0000117 NCBI chr11:53,397,380...53,410,596 JBrowse link
G PARS2 prolyl-tRNA synthetase 2, mitochondrial involved_in IEA UniProt GO_REF:0000117 NCBI chr20:78,172,890...78,180,901
Ensembl chr20:78,178,634...78,180,061
JBrowse link
G TARS1 threonyl-tRNA synthetase 1 involved_in IEA UniProt GO_REF:0000117 NCBI chr 4:32,670,020...32,697,608
Ensembl chr 4:32,670,203...32,699,168
JBrowse link
G TARS2 threonyl-tRNA synthetase 2, mitochondrial involved_in IEA UniProt GO_REF:0000117
G TARS3 threonyl-tRNA synthetase 3 involved_in IEA UniProt GO_REF:0000117 NCBI chr29:20,106,215...20,198,227
Ensembl chr29:20,105,747...20,185,159
JBrowse link
tryptophanyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WARS1 tryptophanyl-tRNA synthetase 1 involved_in IEA Ensembl
TreeGrafter
InterPro
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr24:78,296,154...78,340,683
Ensembl chr24:78,295,741...78,339,732
JBrowse link
G WARS2 tryptophanyl tRNA synthetase 2, mitochondrial involved_in IEA InterPro GO_REF:0000002 NCBI chr20:14,614,902...14,726,630
Ensembl chr20:14,615,349...14,726,780
JBrowse link
tyrosyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC103228400 tyrosine--tRNA ligase, mitochondrial-like involved_in IEA InterPro GO_REF:0000002 NCBI chr22:74,734,656...74,736,422 JBrowse link
G YARS1 tyrosyl-tRNA synthetase 1 involved_in IEA InterPro
Ensembl
GO_REF:0000002 GO_REF:0000107 NCBI chr20:100,050,717...100,096,719
Ensembl chr20:100,052,535...100,095,980
JBrowse link
G YARS2 tyrosyl-tRNA synthetase 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr11:32,181,214...32,192,654
Ensembl chr11:32,181,397...32,192,454
JBrowse link
valyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G VARS1 valyl-tRNA synthetase 1 involved_in IEA InterPro
TreeGrafter
GO_REF:0000002 GO_REF:0000118 NCBI chr17:40,228,217...40,245,366
Ensembl chr17:40,228,938...40,245,287
JBrowse link
G VARS2 valyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro
TreeGrafter
GO_REF:0000002 GO_REF:0000118 NCBI chr17:41,537,842...41,550,063
Ensembl chr17:41,534,552...41,549,439
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17022
    cellular process 16536
      metabolic process 10907
        primary metabolic process 9688
          amino acid metabolic process 294
            amino acid activation 46
              tRNA aminoacylation 45
                asparaginyl-tRNAAsn biosynthesis via transamidation 0
                glutaminyl-tRNAGln biosynthesis via transamidation 3
                tRNA aminoacylation for nonribosomal peptide biosynthetic process 0
                tRNA aminoacylation for protein translation + 42
Path 2
Term Annotations click to browse term
  biological_process 17022
    cellular process 16536
      metabolic process 10907
        primary metabolic process 9688
          nucleobase-containing compound metabolic process 5445
            nucleic acid metabolic process 4919
              RNA metabolic process 4374
                tRNA metabolic process 189
                  tRNA aminoacylation 45
                    asparaginyl-tRNAAsn biosynthesis via transamidation 0
                    glutaminyl-tRNAGln biosynthesis via transamidation 3
                    tRNA aminoacylation for nonribosomal peptide biosynthetic process 0
                    tRNA aminoacylation for protein translation + 42
paths to the root