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ONTOLOGY REPORT - ANNOTATIONS

Term:T cell differentiation in thymus
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Accession:GO:0033077 term browser browse the term
Definition:The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: thymic T cell differentiation;   thymocyte cell differentiation;   thymocyte differentiation
 related_synonym: T cell development in thymus

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T cell differentiation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase acts_upstream_of ISO (PMID:11067867), (PMID:16670300)
(PMID:11435465)
(PMID:11067867), (PMID:12163459), (PMID:16670300)		 MGI PMID:11067867 PMID:11435465 PMID:12163459 PMID:16670300 NCBI chr 2:19,167,209...19,200,233 JBrowse link
G ADAM17 ADAM metallopeptidase domain 17 involved_in ISO (PMID:17371977) BHF-UCL PMID:17371977 NCBI chr14:98,092,093...98,157,657
Ensembl chr14:98,092,044...98,157,217 		JBrowse link
G APC APC regulator of WNT signaling pathway acts_upstream_of_or_within ISO (PMID:16025118) MGI PMID:16025118 NCBI chr23:15,992,437...16,135,117
Ensembl chr23:16,042,287...16,137,067 		JBrowse link
G B2M beta-2-microglobulin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18776904) Ensembl
MGI		 PMID:18776904 GO_REF:0000107 NCBI chr26:38,331,818...38,338,785
Ensembl chr26:38,331,442...38,338,809 		JBrowse link
G BCL11B BCL11 transcription factor B acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16670294) MGI
Ensembl		 PMID:16670294 GO_REF:0000107 NCBI chr24:77,122,591...77,222,562
Ensembl chr24:77,122,689...77,221,454 		JBrowse link
G BCL2 BCL2 apoptosis regulator acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:8170972), (PMID:9028316) MGI
Ensembl		 PMID:8170972 PMID:9028316 GO_REF:0000107 NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO (PMID:23334952) MGI PMID:23334952 NCBI chr21:109,495,525...109,690,261 JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase involved_in IEA Ensembl GO_REF:0000107 Ensembl chr21:109,545,491...109,690,195 JBrowse link
G CD3E CD3e molecule ISO RGD PMID:11896936 RGD:2313407 NCBI chr 1:109,681,142...109,692,835
Ensembl chr 1:109,681,065...109,692,839 		JBrowse link
G CDK6 cyclin dependent kinase 6 acts_upstream_of_or_within ISO (PMID:21508411) MGI PMID:21508411 NCBI chr21:56,167,731...56,403,976
Ensembl chr21:56,170,450...56,393,808 		JBrowse link
G CTNNB1 catenin beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16025118) Ensembl
MGI		 PMID:16025118 GO_REF:0000107 NCBI chr22:2,679,488...2,725,034
Ensembl chr22:2,684,022...2,723,949 		JBrowse link
G DNAJA3 DnaJ heat shock protein family (Hsp40) member A3 acts_upstream_of_or_within ISO (PMID:15879105) MGI PMID:15879105 NCBI chr 5:4,109,612...4,139,789 JBrowse link
G DNAJA3 DnaJ heat shock protein family (Hsp40) member A3 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 5:4,109,577...4,137,926 JBrowse link
G FADD Fas associated via death domain involved_in ISO (PMID:21876153) UniProt PMID:21876153 NCBI chr 1:4,358,314...4,361,863 JBrowse link
G FZD5 frizzled class receptor 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11265645) Ensembl
MGI		 PMID:11265645 GO_REF:0000107 NCBI chr10:93,545,792...93,553,092
Ensembl chr10:93,550,189...93,551,946 		JBrowse link
G FZD7 frizzled class receptor 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11265645) Ensembl
MGI		 PMID:11265645 GO_REF:0000107 NCBI chr10:87,734,263...87,738,676
Ensembl chr10:87,734,872...87,736,596 		JBrowse link
G FZD8 frizzled class receptor 8 acts_upstream_of_or_within ISO (PMID:11265645) MGI PMID:11265645 NCBI chr 9:34,918,916...34,922,687 JBrowse link
G GATA3 GATA binding protein 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:14670303)
(PMID:8945476)
(PMID:19934022)
(PMID:18776904)		 MGI
Ensembl		 PMID:8945476 PMID:14670303 PMID:18776904 PMID:19934022 GO_REF:0000107 NCBI chr 9:8,101,404...8,122,762
Ensembl chr 9:8,101,432...8,123,064 		JBrowse link
G GBA1 glucosylceramidase beta 1 acts_upstream_of_or_within ISO (PMID:22665763) MGI PMID:22665763 NCBI chr20:8,598,110...8,631,517
Ensembl chr20:8,598,628...8,630,990 		JBrowse link
G GLI3 GLI family zinc finger 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15855276) Ensembl
MGI		 PMID:15855276 GO_REF:0000107 NCBI chr21:16,386,700...16,665,648
Ensembl chr21:16,549,789...16,662,238 		JBrowse link
G IL2RG interleukin 2 receptor subunit gamma involved_in
acts_upstream_of		 IEA
ISO		 (PMID:9252128)
(PMID:9916699)		 Ensembl
MGI		 PMID:9252128 PMID:9916699 GO_REF:0000107 NCBI chr  X:60,905,011...60,915,723
Ensembl chr  X:60,905,343...60,909,149 		JBrowse link
G IL7R interleukin 7 receptor acts_upstream_of
involved_in		 ISO
IEA		 (PMID:9215626) MGI
Ensembl		 PMID:9215626 GO_REF:0000107 NCBI chr 4:34,701,724...34,724,241
Ensembl chr 4:34,701,531...34,721,361 		JBrowse link
G JMJD6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14715629) Ensembl
MGI		 PMID:14715629 GO_REF:0000107 NCBI chr16:44,955,617...44,970,136
Ensembl chr16:44,955,778...44,970,133 		JBrowse link
G LOC103230489 major histocompatibility complex class I-related gene protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:48,348,439...48,370,242
Ensembl chr25:48,348,196...48,369,483 		JBrowse link
G LOC103243413 signal transducer and activator of transcription 5B acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:15294943) MGI
Ensembl		 PMID:15294943 GO_REF:0000107 NCBI chr16:63,997,486...64,070,392
Ensembl chr16:63,997,441...64,070,445 		JBrowse link
G LOC119623630 lysosomal acid glucosylceramidase involved_in IEA Ensembl GO_REF:0000107
G MAFB MAF bZIP transcription factor B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19164599) Ensembl
MGI		 PMID:19164599 GO_REF:0000107 NCBI chr 2:23,092,547...23,097,721
Ensembl chr 2:23,094,713...23,095,684 		JBrowse link
G MPZL2 myelin protein zero like 2 acts_upstream_of_or_within ISO (PMID:19851463) MGI PMID:19851463 NCBI chr 1:109,635,053...109,645,142
Ensembl chr 1:109,633,493...109,645,145 		JBrowse link
G NCAPH2 non-SMC condensin II complex subunit H2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17640884) Ensembl
MGI		 PMID:17640884 GO_REF:0000107 NCBI chr19:32,978,771...32,995,055
Ensembl chr19:32,978,562...32,997,160 		JBrowse link
G NCOR1 nuclear receptor corepressor 1 acts_upstream_of_or_within ISO (PMID:11030619) MGI PMID:11030619 NCBI chr16:15,442,315...15,629,411
Ensembl chr16:15,462,640...15,628,512 		JBrowse link
G NFKBID NFKB inhibitor delta acts_upstream_of ISO (PMID:11931770) MGI PMID:11931770 NCBI chr 6:30,800,122...30,812,991
Ensembl chr 6:30,799,204...30,811,141 		JBrowse link
G NKAP NFKB activating protein acts_upstream_of_or_within ISO (PMID:20610818) MGI PMID:20610818
G PRKDC protein kinase, DNA-activated, catalytic subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9768755) Ensembl
MGI		 PMID:9768755 GO_REF:0000107 NCBI chr 8:43,915,226...44,119,547
Ensembl chr 8:43,914,636...44,119,541 		JBrowse link
G PRR7 proline rich 7, synaptic involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:79,458,347...79,467,421
Ensembl chr23:79,466,186...79,467,257 		JBrowse link
G PSMB11 proteasome subunit beta 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:31915251) Ensembl
MGI		 PMID:31915251 GO_REF:0000107 NCBI chr29:23,410,583...23,413,099
Ensembl chr29:23,411,557...23,412,459 		JBrowse link
G RABL3 RAB, member of RAS oncogene family like 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:60,095,013...60,133,189
Ensembl chr22:60,095,066...60,136,337 		JBrowse link
G RAG1 recombination activating 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9215624) Ensembl
MGI
UniProt		 PMID:9215624 GO_REF:0000104 GO_REF:0000107 NCBI chr 1:28,667,996...28,701,002 JBrowse link
G RAG2 recombination activating 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:28,645,175...28,653,823
Ensembl chr 1:28,649,930...28,651,513 		JBrowse link
G RIPK3 receptor interacting serine/threonine kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:1,318,265...1,322,610
Ensembl chr24:1,318,216...1,322,462 		JBrowse link
G RORC RAR related orphan receptor C acts_upstream_of_or_within ISO (PMID:15247480) MGI PMID:15247480 NCBI chr20:11,854,911...11,880,221
Ensembl chr20:11,855,005...11,879,717 		JBrowse link
G RPS6 ribosomal protein S6 acts_upstream_of_or_within ISO (PMID:16357222) MGI PMID:16357222 NCBI chr12:60,353,800...60,357,797
Ensembl chr12:60,353,817...60,357,759 		JBrowse link
G SHH sonic hedgehog signaling molecule involved_in
acts_upstream_of		 IEA
ISO		 (PMID:10981962) Ensembl
MGI		 PMID:10981962 GO_REF:0000107 NCBI chr21:123,929,937...123,942,451
Ensembl chr21:123,932,900...123,942,395 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO (PMID:15294943) MGI PMID:15294943 NCBI chr16:63,959,265...63,986,627
Ensembl chr16:63,960,515...63,985,026 		JBrowse link
G TCF3 transcription factor 3 acts_upstream_of_or_within ISO (PMID:18958875) MGI PMID:18958875 NCBI chr 6:1,393,147...1,440,515
Ensembl chr 6:1,393,107...1,440,479 		JBrowse link
G TESPA1 thymocyte expressed, positive selection associated 1 acts_upstream_of ISO (PMID:28598420) MGI PMID:28598420 NCBI chr11:51,044,269...51,079,210
Ensembl chr11:51,042,095...51,070,939 		JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16357222) Ensembl
MGI		 PMID:16357222 GO_REF:0000107 NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223 		JBrowse link
G WNT1 Wnt family member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11265645) Ensembl
MGI		 PMID:11265645 GO_REF:0000107 NCBI chr11:45,217,402...45,222,996
Ensembl chr11:45,219,027...45,222,017 		JBrowse link
G WNT4 Wnt family member 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11265645) Ensembl
MGI		 PMID:11265645 GO_REF:0000107 NCBI chr20:110,517,391...110,543,802
Ensembl chr20:110,517,564...110,541,203 		JBrowse link
G ZBTB1 zinc finger and BTB domain containing 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22201126) Ensembl
MGI		 PMID:22201126 GO_REF:0000107 NCBI chr24:41,712,721...41,738,853
Ensembl chr24:41,712,114...41,740,654 		JBrowse link
G ZFP36L1 ZFP36 ring finger protein like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:46,000,222...46,005,455
Ensembl chr24:45,999,623...46,006,218 		JBrowse link
G ZFP36L2 ZFP36 ring finger protein like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:64,019,633...64,022,301
Ensembl chr14:64,019,418...64,026,281 		JBrowse link
DN2 thymocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCR6 C-C motif chemokine receptor 6 involved_in ISO (PMID:24638065) UniProt PMID:24638065 NCBI chr13:94,865,480...94,894,331
Ensembl chr13:94,865,936...94,894,315 		JBrowse link
G LIG4 DNA ligase 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:10911993), (PMID:9823897) MGI
Ensembl		 PMID:9823897 PMID:10911993 GO_REF:0000107 NCBI chr 3:86,576,200...86,587,097
Ensembl chr 3:86,577,304...86,580,039 		JBrowse link
G RAG2 recombination activating 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:9875844) MGI
Ensembl		 PMID:9875844 GO_REF:0000107 NCBI chr 1:28,645,175...28,653,823
Ensembl chr 1:28,649,930...28,651,513 		JBrowse link
G XRCC4 X-ray repair cross complementing 4 acts_upstream_of_or_within ISO (PMID:9875844) MGI PMID:9875844 NCBI chr 4:77,182,569...77,468,786
Ensembl chr 4:77,182,793...77,468,775 		JBrowse link
DN3 thymocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCR6 C-C motif chemokine receptor 6 involved_in ISO (PMID:24638065) UniProt PMID:24638065 NCBI chr13:94,865,480...94,894,331
Ensembl chr13:94,865,936...94,894,315 		JBrowse link
DN4 thymocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:18025176) MGI
Ensembl		 PMID:18025176 GO_REF:0000107 NCBI chr12:7,258,932...7,435,658
Ensembl chr12:7,256,648...7,312,734 		JBrowse link
G ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:18025176) MGI PMID:18025176 NCBI chr25:50,106,621...50,244,002
Ensembl chr25:50,216,483...50,241,621 		JBrowse link
G BLM BLM RecQ like helicase acts_upstream_of_or_within ISO (PMID:17210642) MGI PMID:17210642 NCBI chr29:9,046,485...9,152,320
Ensembl chr29:9,045,373...9,152,254 		JBrowse link
G NFATC3 nuclear factor of activated T cells 3 involved_in ISO (PMID:17579027) UniProt PMID:17579027 NCBI chr 5:59,193,139...59,346,361 JBrowse link
immature T cell proliferation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BLM BLM RecQ like helicase acts_upstream_of ISO (PMID:17210642) MGI PMID:17210642 NCBI chr29:9,046,485...9,152,320
Ensembl chr29:9,045,373...9,152,254 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 acts_upstream_of
involved_in		 ISO
IEA		 (PMID:16230479) MGI
Ensembl		 PMID:16230479 GO_REF:0000107 NCBI chr16:66,435,488...66,464,993
Ensembl chr16:66,434,251...66,464,952 		JBrowse link
G FOXP3 forkhead box P3 acts_upstream_of ISO (PMID:16230479) MGI PMID:16230479 NCBI chr  X:46,349,890...46,365,133 JBrowse link
G FOXP3 forkhead box P3 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr  X:46,346,754...46,356,928 JBrowse link
G IFNAR2 interferon alpha and beta receptor subunit 2 acts_upstream_of_or_within ISO (PMID:11154225) MGI PMID:11154225 NCBI chr 2:58,920,237...58,954,809
Ensembl chr 2:58,918,433...58,954,790 		JBrowse link
G LOC103233812 C-type lectin domain family 4 member G acts_upstream_of ISO (PMID:23487419) MGI PMID:23487419 NCBI chr 6:7,206,303...7,211,213
Ensembl chr 6:7,206,712...7,209,431 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:11894098) Ensembl
MGI		 PMID:11894098 GO_REF:0000107 NCBI chr 8:84,843,391...84,881,087
Ensembl chr 8:84,843,471...84,881,303 		JBrowse link
G WNT4 Wnt family member 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18617424) Ensembl
MGI		 PMID:18617424 GO_REF:0000107 NCBI chr20:110,517,391...110,543,802
Ensembl chr20:110,517,564...110,541,203 		JBrowse link
negative regulation of immature T cell proliferation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:31,097,673...31,104,774
Ensembl chr24:31,097,538...31,101,225 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16230479) MGI
Ensembl		 PMID:16230479 GO_REF:0000107 NCBI chr16:66,435,488...66,464,993
Ensembl chr16:66,434,251...66,464,952 		JBrowse link
G IHH Indian hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:104,960,296...104,966,596
Ensembl chr10:104,960,120...104,966,585 		JBrowse link
G LOC103233812 C-type lectin domain family 4 member G acts_upstream_of_or_within ISO (PMID:23487419) MGI PMID:23487419 NCBI chr 6:7,206,303...7,211,213
Ensembl chr 6:7,206,712...7,209,431 		JBrowse link
G TMEM131L transmembrane 131 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:100,021,779...100,190,136
Ensembl chr 7:100,021,797...100,191,255 		JBrowse link
negative regulation of positive thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:71,302,082...71,400,201
Ensembl chr18:71,310,577...71,345,960 		JBrowse link
negative regulation of T cell differentiation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:31,097,673...31,104,774
Ensembl chr24:31,097,538...31,101,225 		JBrowse link
G FOXJ1 forkhead box J1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:45,536,973...45,544,331
Ensembl chr16:45,539,510...45,544,299 		JBrowse link
G IHH Indian hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:104,960,296...104,966,596
Ensembl chr10:104,960,120...104,966,585 		JBrowse link
G NFKBID NFKB inhibitor delta acts_upstream_of_or_within ISO (PMID:11931770) MGI PMID:11931770 NCBI chr 6:30,800,122...30,812,991
Ensembl chr 6:30,799,204...30,811,141 		JBrowse link
G RAG2 recombination activating 2 ISO RGD PMID:30206106 RGD:38508903 NCBI chr 1:28,645,175...28,653,823
Ensembl chr 1:28,649,930...28,651,513 		JBrowse link
G SHH sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10981962) Ensembl
MGI		 PMID:10981962 GO_REF:0000107 NCBI chr21:123,929,937...123,942,451
Ensembl chr21:123,932,900...123,942,395 		JBrowse link
G ZC3H8 zinc finger CCCH-type containing 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:15,284,640...15,325,931
Ensembl chr14:15,303,456...15,325,878 		JBrowse link
negative thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIRE autoimmune regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23382543) Ensembl
MGI		 PMID:23382543 GO_REF:0000107 NCBI chr 2:88,019,122...88,031,998
Ensembl chr 2:88,019,522...88,031,801 		JBrowse link
G ATG5 autophagy related 5 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:23382543) MGI
Ensembl		 PMID:23382543 GO_REF:0000107 NCBI chr13:67,482,538...67,619,201
Ensembl chr13:67,482,595...67,617,902 		JBrowse link
G CCR7 C-C motif chemokine receptor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:65,620,632...65,632,394
Ensembl chr16:65,620,665...65,632,984 		JBrowse link
G CD28 CD28 molecule acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:10429671) MGI
Ensembl		 PMID:10429671 GO_REF:0000107 NCBI chr10:89,471,710...89,505,152
Ensembl chr10:89,471,730...89,500,387 		JBrowse link
G CD3E CD3e molecule acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:7630421) MGI
Ensembl		 PMID:7630421 GO_REF:0000107 NCBI chr 1:109,681,142...109,692,835
Ensembl chr 1:109,681,065...109,692,839 		JBrowse link
G CD74 CD74 molecule acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:7679955) MGI
Ensembl		 PMID:7679955 GO_REF:0000107 NCBI chr23:53,008,802...53,022,953
Ensembl chr23:53,009,394...53,022,923 		JBrowse link
G DOCK2 dedicator of cytokinesis 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12871644) Ensembl
MGI		 PMID:12871644 GO_REF:0000107 NCBI chr23:71,866,196...72,299,066
Ensembl chr23:71,866,251...72,299,056 		JBrowse link
G GLI3 GLI family zinc finger 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:16,386,700...16,665,648
Ensembl chr21:16,549,789...16,662,238 		JBrowse link
G LOC103241092 tyrosine-protein kinase ZAP-70 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7630421) Ensembl
MGI		 PMID:7630421 GO_REF:0000107 NCBI chr14:1,403,294...1,430,205
Ensembl chr14:1,404,325...1,431,015 		JBrowse link
G MINK1 misshapen like kinase 1 acts_upstream_of_or_within ISO (PMID:15608642) MGI PMID:15608642 NCBI chr16:4,305,680...4,370,554
Ensembl chr16:4,305,701...4,369,780 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8666928) Ensembl
MGI		 PMID:8666928 GO_REF:0000107 NCBI chr25:30,655,014...30,777,367
Ensembl chr25:30,653,044...30,777,303 		JBrowse link
G SHH sonic hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:123,929,937...123,942,451
Ensembl chr21:123,932,900...123,942,395 		JBrowse link
G SPN sialophorin acts_upstream_of_or_within ISO (PMID:10429671) MGI PMID:10429671 NCBI chr 5:26,987,810...26,990,214 JBrowse link
positive regulation of immature T cell proliferation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BLM BLM RecQ like helicase acts_upstream_of_or_within ISO (PMID:17210642) MGI PMID:17210642 NCBI chr29:9,046,485...9,152,320
Ensembl chr29:9,045,373...9,152,254 		JBrowse link
G BMI1 BMI1 proto-oncogene, polycomb ring finger involved_in ISO (PMID:15964995) HGNC-UCL PMID:15964995 NCBI chr 9:22,095,592...22,104,894 JBrowse link
G BMI1 BMI1 proto-oncogene, polycomb ring finger involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 9:22,090,437...22,105,447 JBrowse link
G FOXP3 forkhead box P3 acts_upstream_of_or_within ISO (PMID:16230479) MGI PMID:16230479 NCBI chr  X:46,349,890...46,365,133 JBrowse link
G FOXP3 forkhead box P3 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr  X:46,346,754...46,356,928 JBrowse link
G IL1A interleukin 1 alpha involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:15,789,710...15,801,938
Ensembl chr14:15,789,013...15,796,611 		JBrowse link
G IL1B interleukin 1 beta involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:8590311 GO_REF:0000118 RGD:7401228 NCBI chr14:15,844,628...15,852,652
Ensembl chr14:15,844,672...15,850,729 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11894098) Ensembl
MGI		 PMID:11894098 GO_REF:0000107 NCBI chr 8:84,843,391...84,881,087
Ensembl chr 8:84,843,471...84,881,303 		JBrowse link
G SHH sonic hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:123,929,937...123,942,451
Ensembl chr21:123,932,900...123,942,395 		JBrowse link
positive regulation of T cell differentiation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase acts_upstream_of_or_within ISO (PMID:11067867), (PMID:16670300)
(PMID:11067867), (PMID:12163459), (PMID:16670300)
(PMID:11435465)		 MGI PMID:11067867 PMID:11435465 PMID:12163459 PMID:16670300 NCBI chr 2:19,167,209...19,200,233 JBrowse link
G ADAM8 ADAM metallopeptidase domain 8 involved_in ISO (PMID:20856819) BHF-UCL PMID:20856819 NCBI chr26:53,114,184...53,129,650
Ensembl chr26:53,114,924...53,126,900 		JBrowse link
G EGR3 early growth response 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21737317) Ensembl
MGI		 PMID:21737317 GO_REF:0000107 NCBI chr 8:20,767,219...20,772,838
Ensembl chr 8:20,767,224...20,772,682 		JBrowse link
G IHH Indian hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:104,960,296...104,966,596
Ensembl chr10:104,960,120...104,966,585 		JBrowse link
G IL2RG interleukin 2 receptor subunit gamma involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9252128)
(PMID:9916699)		 Ensembl
MGI		 PMID:9252128 PMID:9916699 GO_REF:0000107 NCBI chr  X:60,905,011...60,915,723
Ensembl chr  X:60,905,343...60,909,149 		JBrowse link
G IL7R interleukin 7 receptor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:9215626) MGI
Ensembl		 PMID:9215626 GO_REF:0000107 NCBI chr 4:34,701,724...34,724,241
Ensembl chr 4:34,701,531...34,721,361 		JBrowse link
G LOC103240354 pantetheinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:40,819,738...40,853,827
Ensembl chr13:40,819,950...40,855,171 		JBrowse link
G RASGRP1 RAS guanyl releasing protein 1 involved_in ISO (PMID:11017103) CACAO PMID:11017103 NCBI chr26:44,405,007...44,483,291 JBrowse link
G RASGRP1 RAS guanyl releasing protein 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr26:44,451,634...44,486,570 JBrowse link
G SHH sonic hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:123,929,937...123,942,451
Ensembl chr21:123,932,900...123,942,395 		JBrowse link
G TESPA1 thymocyte expressed, positive selection associated 1 involved_in ISO (PMID:22561606) UniProt PMID:22561606 NCBI chr11:51,044,269...51,079,210
Ensembl chr11:51,042,095...51,070,939 		JBrowse link
positive thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD1D CD1d molecule acts_upstream_of_or_within ISO (PMID:9133426) MGI PMID:9133426 NCBI chr20:5,726,307...5,733,355
Ensembl chr20:5,727,049...5,730,061 		JBrowse link
G CD3D CD3d molecule involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:109,715,148...109,719,576
Ensembl chr 1:109,713,017...109,719,950 		JBrowse link
G CD3E CD3e molecule involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:109,681,142...109,692,835
Ensembl chr 1:109,681,065...109,692,839 		JBrowse link
G CD3G CD3g molecule involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:109,721,150...109,730,267
Ensembl chr 1:109,720,789...109,732,014 		JBrowse link
G CD74 CD74 molecule acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:9432982)
(PMID:7679955), (PMID:8598040)		 MGI
Ensembl		 PMID:7679955 PMID:8598040 PMID:9432982 GO_REF:0000107 NCBI chr23:53,008,802...53,022,953
Ensembl chr23:53,009,394...53,022,923 		JBrowse link
G DOCK2 dedicator of cytokinesis 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12871644) Ensembl
MGI		 PMID:12871644 GO_REF:0000107 NCBI chr23:71,866,196...72,299,066
Ensembl chr23:71,866,251...72,299,056 		JBrowse link
G ITPKB inositol-trisphosphate 3-kinase B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15064401) Ensembl
MGI		 PMID:15064401 GO_REF:0000107 NCBI chr25:3,009,464...3,117,729
Ensembl chr25:3,009,353...3,118,235 		JBrowse link
G LOC103241092 tyrosine-protein kinase ZAP-70 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:7630421) MGI
Ensembl		 PMID:7630421 GO_REF:0000107 NCBI chr14:1,403,294...1,430,205
Ensembl chr14:1,404,325...1,431,015 		JBrowse link
G MHC-DMA HLA class II histocompatibility antigen, DM alpha chain acts_upstream_of_or_within ISO (PMID:8598040)
(PMID:8638109)
(PMID:8598041), (PMID:9432982)		 MGI PMID:8598040 PMID:8598041 PMID:8638109 PMID:9432982 NCBI chr17:39,142,340...39,151,804
Ensembl chr17:39,142,395...39,146,252 		JBrowse link
G NFATC3 nuclear factor of activated T cells 3 involved_in ISO (PMID:17579027) UniProt PMID:17579027 NCBI chr 5:59,193,139...59,346,361 JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8666928) Ensembl
MGI		 PMID:8666928 GO_REF:0000107 NCBI chr25:30,655,014...30,777,367
Ensembl chr25:30,653,044...30,777,303 		JBrowse link
G SHH sonic hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:123,929,937...123,942,451
Ensembl chr21:123,932,900...123,942,395 		JBrowse link
G SRF serum response factor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:21098124) MGI
Ensembl		 PMID:21098124 GO_REF:0000107 NCBI chr17:28,983,161...28,993,465
Ensembl chr17:28,983,002...28,992,995 		JBrowse link
G STK11 serine/threonine kinase 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21487392) Ensembl
MGI		 PMID:21487392 GO_REF:0000107 NCBI chr 6:973,033...996,857
Ensembl chr 6:974,144...995,136 		JBrowse link
regulation of immature T cell proliferation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD1D CD1d molecule involved_in ISO (PMID:11550008) CACAO PMID:11550008 NCBI chr20:5,726,307...5,733,355
Ensembl chr20:5,727,049...5,730,061 		JBrowse link
G TNFRSF9 TNF receptor superfamily member 9 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:8405064) MGI
Ensembl		 PMID:8405064 GO_REF:0000107 NCBI chr20:123,808,289...123,839,957
Ensembl chr20:123,820,342...123,838,987 		JBrowse link
G TNFSF9 TNF superfamily member 9 acts_upstream_of_or_within ISO (PMID:8405064) MGI PMID:8405064 NCBI chr 6:6,131,157...6,136,345
Ensembl chr 6:6,131,571...6,135,463 		JBrowse link
regulation of positive thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXN1 forkhead box N1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:22,291,597...22,306,977
Ensembl chr16:22,292,330...22,305,968 		JBrowse link
G TOX thymocyte selection associated high mobility group box involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:54,777,490...55,086,819
Ensembl chr 8:54,776,015...54,927,091 		JBrowse link
regulation of T cell differentiation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase ISO RGD PMID:3876160 RGD:152995412 NCBI chr 2:19,167,209...19,200,233 JBrowse link
G ADRM1 ADRM1 26S proteasome ubiquitin receptor involved_in ISO (PMID:21048919) BHF-UCL PMID:21048919 NCBI chr 2:1,930,281...1,936,323
Ensembl chr 2:1,925,382...1,936,393 		JBrowse link
G ANKLE1 ankyrin repeat and LEM domain containing 1 NOT|involved_in ISO (PMID:27010503) UniProt PMID:27010503 NCBI chr 6:15,788,861...15,794,825
Ensembl chr 6:15,789,355...15,795,025 		JBrowse link
G CLPTM1 CLPTM1 regulator of GABA type A receptor forward trafficking involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:38,416,268...38,452,578
Ensembl chr 6:38,415,788...38,452,679 		JBrowse link
G FOXN1 forkhead box N1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22072979) Ensembl
MGI		 PMID:22072979 GO_REF:0000107 NCBI chr16:22,291,597...22,306,977
Ensembl chr16:22,292,330...22,305,968 		JBrowse link
G LOC103242599 galectin-9 NOT|involved_in ISO (PMID:25065622) UniProt PMID:25065622 NCBI chr16:21,421,034...21,439,583 JBrowse link
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24043312) Ensembl
MGI		 PMID:24043312 GO_REF:0000107 NCBI chr14:68,259,509...68,404,167
Ensembl chr14:68,259,360...68,399,895 		JBrowse link
G SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:24043312) MGI
Ensembl		 PMID:24043312 GO_REF:0000107 NCBI chr24:27,183,571...27,302,201
Ensembl chr24:27,182,991...27,302,141 		JBrowse link
G ZEB1 zinc finger E-box binding homeobox 1 acts_upstream_of_or_within ISO (PMID:9126927)
(PMID:9389660)		 MGI PMID:9126927 PMID:9389660 NCBI chr 9:30,674,893...30,862,682
Ensembl chr 9:30,674,578...30,863,250 		JBrowse link
thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARD11 caspase recruitment domain family member 11 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr28:18,675,524...18,715,388 JBrowse link
G GATA3 GATA binding protein 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:14670303) MGI
Ensembl		 PMID:14670303 GO_REF:0000107 NCBI chr 9:8,101,404...8,122,762
Ensembl chr 9:8,101,432...8,123,064 		JBrowse link
G ITPKB inositol-trisphosphate 3-kinase B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14517551) Ensembl
MGI		 PMID:14517551 GO_REF:0000107 NCBI chr25:3,009,464...3,117,729
Ensembl chr25:3,009,353...3,118,235 		JBrowse link
G JAG2 jagged canonical Notch ligand 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:83,050,412...83,081,982
Ensembl chr24:83,051,368...83,076,820 		JBrowse link
G LOC103241092 tyrosine-protein kinase ZAP-70 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9208839) Ensembl
MGI		 PMID:9208839 GO_REF:0000107 NCBI chr14:1,403,294...1,430,205
Ensembl chr14:1,404,325...1,431,015 		JBrowse link
G LOC103246958 caspase recruitment domain-containing protein 11 acts_upstream_of_or_within ISO (PMID:12867038) MGI PMID:12867038 NCBI chr28:18,657,941...18,714,202 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19806
    immune system process 2668
      leukocyte activation 1031
        lymphocyte activation 845
          lymphocyte differentiation 453
            T cell differentiation 338
              T cell differentiation in thymus 110
                DN2 thymocyte differentiation 4
                DN3 thymocyte differentiation 1
                DN4 thymocyte differentiation 4
                immature T cell proliferation in thymus + 19
                negative regulation of T cell differentiation in thymus + 11
                positive regulation of T cell differentiation in thymus + 11
                regulation of T cell differentiation in thymus + 29
                thymic T cell selection + 28
Path 2
Term Annotations click to browse term
  biological_process 19806
    developmental process 6822
      cellular developmental process 4575
        cell differentiation 4574
          cell development 3260
            hemopoiesis 1051
              leukocyte differentiation 683
                mononuclear cell differentiation 554
                  lymphocyte differentiation 453
                    T cell differentiation 338
                      T cell differentiation in thymus 110
                        DN2 thymocyte differentiation 4
                        DN3 thymocyte differentiation 1
                        DN4 thymocyte differentiation 4
                        immature T cell proliferation in thymus + 19
                        negative regulation of T cell differentiation in thymus + 11
                        positive regulation of T cell differentiation in thymus + 11
                        regulation of T cell differentiation in thymus + 29
                        thymic T cell selection + 28
paths to the root