ANKLE1 (ankyrin repeat and LEM domain containing 1)

Gene: ANKLE1 (ankyrin repeat and LEM domain containing 1) Chlorocebus sabaeus

Analyze

Symbol:

ANKLE1

Name:

ankyrin repeat and LEM domain containing 1

RGD ID:

18508426

Description:

ENCODES a protein that exhibits DNA endonuclease activity (inferred); endonuclease activity (inferred); INVOLVED IN determination of adult lifespan (ortholog); DNA damage response (ortholog); DNA repair (ortholog); ASSOCIATED WITH COVID-19 (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

ankyrin repeat and LEM domain-containing protein 1

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	15,788,861 - 15,794,825 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	15,789,355 - 15,795,025 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666074	3,633,798 - 3,653,328 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

COVID-19 (ISO)

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

determination of adult lifespan (ISO)

DNA damage response (IEA,ISO)

DNA repair (ISO)

double-strand break repair via homologous recombination (IEA)

erythrocyte maturation (ISO)

negative regulation of mitotic recombination (IEA)

protein export from nucleus (IEA)

regulation of alpha-beta T cell differentiation (ISO)

regulation of B cell differentiation (ISO)

regulation of lymphoid progenitor cell differentiation (IEA)

regulation of myeloid progenitor cell differentiation (IEA)

regulation of T cell differentiation in thymus (ISO)

resolution of meiotic recombination intermediates (IEA)

Cellular Component

cytoplasm (IEA)

cytosol (IEA)

nucleoplasm (IEA)

nucleus (IEA)

Molecular Function

DNA endonuclease activity (IEA)

endonuclease activity (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

ANKLE1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	15,788,861 - 15,794,825 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	15,789,355 - 15,795,025 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666074	3,633,798 - 3,653,328 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

ANKLE1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	17,281,901 - 17,287,646 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	17,281,645 - 17,287,646 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	17,392,710 - 17,398,455 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	17,253,454 - 17,259,454 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	19	17,294,193 - 17,300,193 (+)	NCBI		Celera
Cytogenetic Map	19	p13.11	NCBI
HuRef	19	16,959,113 - 16,965,109 (+)	NCBI		HuRef
CHM1_1	19	17,391,919 - 17,397,928 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	17,416,788 - 17,422,534 (+)	NCBI		T2T-CHM13v2.0

Ankle1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	71,858,630 - 71,868,475 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	71,858,654 - 71,862,548 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	71,405,986 - 71,410,728 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	71,406,010 - 71,409,904 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	73,929,911 - 73,933,803 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	74,335,005 - 74,338,857 (+)	NCBI		MGSCv36	mm8
Celera	8	73,930,693 - 73,934,585 (+)	NCBI		Celera
Cytogenetic Map	8	B3.3	NCBI
cM Map	8	34.43	NCBI

Ankle1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	18,109,865 - 18,116,999 (+)	NCBI		GRCr8
mRatBN7.2	16	18,076,413 - 18,082,356 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	18,076,492 - 18,083,729 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	16	19,799,943 - 19,826,057 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	19,800,463 - 19,803,796 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	19,660,504 - 19,666,523 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	18,565,676 - 18,569,219 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	16	18,565,673 - 18,569,007 (+)	NCBI
Celera	16	18,281,567 - 18,307,663 (+)	NCBI		Celera
Cytogenetic Map	16	p14	NCBI

Ankle1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955524	933,200 - 936,933 (-)	NCBI	ChiLan1.0	ChiLan1.0

ANKLE1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	22,150,870 - 22,163,484 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	21,157,443 - 21,164,409 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	16,769,670 - 16,775,114 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	17,744,570 - 17,750,070 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	17,744,570 - 17,750,070 (+)	Ensembl	panpan1.1		panPan2

ANKLE1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	45,461,135 - 45,465,922 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	45,461,676 - 45,465,417 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	45,374,282 - 45,378,573 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	45,947,346 - 45,951,623 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	20	45,183,987 - 45,188,261 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	45,593,769 - 45,598,070 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	45,869,631 - 45,873,928 (-)	NCBI		UU_Cfam_GSD_1.0

Ankle1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	204,019,872 - 204,024,252 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936596	3,569,814 - 3,573,344 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936596	3,568,810 - 3,573,506 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ANKLE1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	60,391,113 - 60,396,687 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	60,391,110 - 60,397,559 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

Ankle1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624908	649,371 - 654,588 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	hemolymphoid system	nervous system
High
Medium
Low	32	20	56
Below cutoff	4		4

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007995701	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007995702	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007995703	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007995704	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007995705	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007995706	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007995707	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007995708	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007995709	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007995710	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005238486	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000042	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000003670 ⟹ ENSCSAP00000001943

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	6	15,789,355 - 15,795,025 (+)	Ensembl

RefSeq Acc Id:

XM_007995703 ⟹ XP_007993894

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	6	15,788,865 - 15,794,825 (+)	NCBI
Vero_WHO_p1.0	NW_023666074	3,648,148 - 3,653,328 (-)	NCBI

Sequence:

show sequence

GCAACCCTCCTGCCTGGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGTGCCTGGCC
TAAGCCTCTCATAAGGCCGTGCGCCCTCCCAGAGGCCACCCTTGCAGAAGATTCCCTGAGACTT
AAAGACCTGGGGCACCCCGGACTTTCCTAATCATAGCTCCACCCACTCGAGGCGGGTGCCTTTG
CGTTTCCCGTTTTTAAATGAGATAGTGGCACACCCGGTGGCATCCTCCCGCCCGGGCTCTTATC
GGCGGTCCCAGCCCTGCTTGAGCGCCTCCGGGTGTCACGGGCCTCTGCGAACACCAAAGCTCTC
GAACCCCGATGTGGACCCCGGTGCGGCGCGGGGCGGCCTGGCTGGGAACCCTGCTCAGCCCCGG
AGAGGGTCCCCACGAGCCGAGGGGCGGAGCGGCGCATGCCCACAAGCCAGCCGCGGGAAGTAGG
AAATCGACCCCCCAGGCGGTGCGCTTCGGACCCCGCCAGGGCATGTGCTCCGAGGCCCTCCTGG
CTCGCAGGTTGCGGGCGGCGCTGCGGGAGGAGGAGCCGTGGGCGGTAGAGGAGCTGCTGCGCTG
CGGCGCGGACCCTAATTTGGTGCTGGAGGATGGCGCAGCTGCTGTGCACTTGGCTGCCGGAGCC
CGGCACCCGCGCGGCCTGCGTTGCCTCGGGGCCCTACTGCGCCAAGGCGGGGACCCCAACGCTC
GATCTGTCGAGGCATTGACACCGCTGCATGTGGCCGCTGCCTGGGGCTGCCGCCGCGGCCTGGA
GCTGCTGCTGAGCCAAGGAGCAAACCCGGCGCTGCGCGACCAGGACGGACTCCGGCCGCTGGAC
CTGGCCCTGCAGCAGGGGCACCTGGAGTGTGCGCGAGTCCTGCAGGATCTCGACACGCGGACCA
GGACCCGGACCCGGATCGGGGCAGAGACCCAGGAGCCCGAGGCTGCACCTGGCACTCCAGGCCT
CTCTGGATCTCCTGATGAGATGCTGGACTCCATAGCACTCCAAACGCAGCCATGCAGAGGTGAC
AACAGGGACACGGGCTTGGAGGCTGACCCAGGAACCCCCAGCCTCCCTGTTCCCCTTGAAATTG
TGGACAAAGATAGGAGCTCAGCGTCCCCTCCAGGGCACTGGGATTACAGCTCAGATGCCTCTTT
CATCACAGCAGTTGAGGTCTCTGGAGCCAAGGACCCAGCCTCGGATACTCCCCCCTGGGCTGGG
TCATTGCCACTGACCAGGCAGGGACTTCTGCATGTTGTCCATGCCACACAGAGGGTACCTAGGT
CTCAGGGGACGGAGGCAGAACTGAATGCCCGTCTGCAGGCCCTGACTCTGACCCCACCAAATGC
TGCTGGCTTCCAGTCCTGCCCTTCCTCCATGCCTCTCCTAGACAGGAGTCCAGCTCACAGCCCC
CCACAGACACCACCCCCTGGAGCTTCTGACTGCCACGGCCTGTGGGAGCACCAGACATCCATTG
ATAGTGACATGGCCACGCTCTGGCTGACAGAGGATGAGGCAAGCTCTACAGGTGGCAGAGACCC
TGTCGGCTGTTGCCAGCACCCGCCAGTCTCCATTGTGTCTGACTTGGAGTTGCTGCAGGGGCTG
CGAGCGCTTGGTGAGAATCCTGGCCCTGTCACACCCTTCACCCGGCGATTCTACCTCCAGCGGC
TGAAAGAAGCCCAGATTGCCCCTGGCCCAGAGTTTTCAGGGCACAGCCTAGAACTGGCTGCAGC
CCTGCGGACAGGCTGTATTCCAGATGTCCAGGCAGATGAAGACGCGCTGGCCCAGCAGTTTGAG
CAGCCAGATCCTGCCAGGAGGTGGCGGGAGGGGGTCGTGAAGTCTAGCTTCACATATCTGCTGC
TGGACCCCAGGGAGACTCAGGACCTGCCAGCCCGAGCCTTCTCACTGACCCCAGCTGAGCGCCT
TCAGACTTTCGTCCGTGCCATCTTCTACGTGGGCAAAGGGACGAGGGCCCGGCCATATGTCCAC
CTCTGGGAAGCCCTTGGTCACCATGGGCGGTCAAGAAAACAGCCCCCCCAGGCCTGCCCCAAGG
TGCGTCAGATCTTGGACATCTGGGCCAGTGGTTGCGGCGTTGTGTCCCTACATTGCTTCCAGCA
TGTGGTCGCTGTGGAGGCTTATACACGGGAGGCGTGTATTGTGGAAGCCCTAGGGATCCAGACG
CTCACCAACCAGAAACAAGGGCACTGCTATGGAGTGGTGGCAGGCTGGCCACCTGCTCGTCGCC
GGCGCTTGGGGGTGCACCTGCTGCACCGCGCCCTCCTCGTCTTCCTGGCTGAAGGCGAGCGACA
GCTTCGTCCCCAGGACATTCAGGCCCGGGGCTGAGTGCTGGGGAGTTGGCCGTCCAGCCTGGGA
AGAAATGTTTGAACGTTCCAGCTGCCCTGTGCTGACAGCAGCCCCCATCTCTGGTTTCAGAAGG
GGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTAGGGAACACCAGGGCAGATCTCCCC
CAGTCTGAGAGAGGACTTTGTTACAGATGGTACTGCTGGAGGGGTAGTAAGTAGTGAGCTCCCC
GTCATGGGAGGAGGACAAGTAGGGAAGCAGAAGGTGCTTAGGAACAGTCCGGTGCTTCTGTCAG
AGGCGTTTGAACCTGGGCAACTCCACCTTGAATAGGAGCTGGGTAAAATGAGGCTGAAACCTAC
TGGGCTGCATTCCCAGACGGTTAAAGCATTCTAAGTCACAGGATGAGGTAGGAGGTCAGCACAA
GATAATGGGTCATAAAGACCTTGCTGATAAAACAGGTTGCAGTAAAGAAGCCGGCCAAAACCCA
CCAATACCAAGATGGCGACAAGAGTGACCTCTGGTCGTCCTCATTTCTACACTCCCACCAGCGC
CATGACAGTTTACAAATGCCATGCCTGGCCAGGCGCGGTGGCTTATGCCTGTAATCCTCGCACT
TTGGGCGGCCAAGGCGGGCAGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGG
TGAAGCCCCGTCTCTACTAAAAATACAAAAATTAGCTGGGCATGGTGGCAAGTGCCTGTAATCC
CAGCTACTAGGGGGGCTGAGGCAGGAGGATCACTTGAACCTGGGAGGCAGAGGTTGCAGTGAGC
TGAGATTGTGCCACTTCACTCCAACCTGGGCAACAGAGCGAGAGTCCGTCTCAAAGAAGCAAAC

hide sequence

RefSeq Acc Id:

XM_007995705 ⟹ XP_007993896

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	6	15,788,863 - 15,794,321 (+)	NCBI
Vero_WHO_p1.0	NW_023666074	3,647,821 - 3,653,328 (-)	NCBI

Sequence:

show sequence

AAGCAACCCTCCTGCCTGGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGTGCCTGG
CCTAAGCCTCTCATAAGGCCGTGCGCCCTCCCAGAGGCCACCCTTGCAGAAGATTCCCTGAGAC
TTAAAGACCTGGGGCACCCCGGACTTTCCTAATCATAGCTCCACCCACTCGAGGCGGGTGCCTT
TGCGTTTCCCGTTTTTAAATGAGATAGTGGCACACCCGGTGGCATCCTCCCGCCCGGGCTCTTA
TCGGCGGTCCCAGCCCTGCTTGAGCGCCTCCGGGTGTCACGGGCCTCTGCGAACACCAAAGCTC
TCGAACCCCGATGTGGACCCCGGTGCGGCGCGGGGCGGCCTGGCTGGGAACCCTGCTCAGCCCC
GGAGAGGGTCCCCACGAGCCGAGGGGCGGAGCGGCGCATGCCCACAAGCCAGCCGCGGGAAGTA
GGAAATCGACCCCCCAGGCGGTGCGCTTCGGACCCCGCCAGGGCATGTGCTCCGAGGCCCTCCT
GGCTCGCAGGTTGCGGGCGGCGCTGCGGGAGGAGGAGCCGTGGGCGGTAGAGGAGCTGCTGCGC
TGCGGCGCGGACCCTAATTTGGTGCTGGAGGATGGCGCAGCTGCTGTGCACTTGGCTGCCGGAG
CCCGGCACCCGCGCGGCCTGCGTTGCCTCGGGGCCCTACTGCGCCAAGGCGGGGACCCCAACGC
TCGATCTGTCGAGGCATTGACACCGCTGCATGTGGCCGCTGCCTGGGGCTGCCGCCGCGGCCTG
GAGCTGCTGCTGAGCCAAGGAGCAAACCCGGCGCTGCGCGACCAGGACGGACTCCGGCCGCTGG
ACCTGGCCCTGCAGCAGGGGCACCTGGAGTGTGCGCGAGTCCTGCAGGATCTCGACACGCGGAC
CAGGACCCGGACCCGGATCGGGGCAGAGACCCAGGAGCCCGAGGCTGCACCTGGCACTCCAGGC
CTCTCTGGATCTCCTGATGAGATGCTGGACTCCATAGCACTCCAAACGCAGCCATGCAGAGGTG
ACAACAGGGACACGGGCTTGGAGGCTGACCCAGGAACCCCCAGCCTCCCTGTTCCCCTTGAAAT
TGTGGACAAAGATAGGAGCTCAGCGTCCCCTCCAGGGCACTGGGATTACAGCTCAGATGCCTCT
TTCATCACAGCAGTTGAGGTCTCTGGAGCCAAGGACCCAGCCTCGGATACTCCCCCCTGGGCTG
GGTCATTGCCACTGACCAGGCAGGGACTTCTGCATGTTGTCCATGCCACACAGAGGGTACCTAG
GTCTCAGGGGACGGAGGCAGAACTGAATGCCCGTCTGCAGGCCCTGACTCTGACCCCACCAAAT
GCTGCTGGCTTCCAGTCCTGCCCTTCCTCCATGCCTCTCCTAGACAGGAGTCCAGCTCACAGCC
CCCCACAGACACCACCCCCTGGAGCTTCTGACTGCCACGGCCTGTGGGAGCACCAGACATCCAT
TGATAGTGACATGGCCACGCTCTGGCTGACAGAGGATGAGGCAAGCTCTACAGGTGGCAGAGAC
CCTGTCGGCTGTTGCCAGCACCCGCCAGTCTCCATTGTGTCTGACTTGGAGTTGCTGCAGGGGC
TGCGAGCGCTTGGCCCAGAGTTTTCAGGGCACAGCCTAGAACTGGCTGCAGCCCTGCGGACAGG
CTGTATTCCAGATGTCCAGGCAGATGAAGACGCGCTGGCCCAGCAGTTTGAGCAGCCAGATCCT
GCCAGGAGGTGGCGGGAGGGGGTCGTGAAGTCTAGCTTCACATATCTGCTGCTGGACCCCAGGG
AGACTCAGGACCTGCCAGCCCGAGCCTTCTCACTGACCCCAGCTGAGCGCCTTCAGACTTTCGT
CCGTGCCATCTTCTACGTGGGCAAAGGGACGAGGGCCCGGCCATATGTCCACCTCTGGGAAGCC
CTTGGTCACCATGGGCGGTCAAGAAAACAGGGATCCAGACGCTCACCAACCAGAAACAAGGGCA
CTGCTATGGAGTGGTGGCAGGCTGGCCACCTGCTCGTCGCCGGCGCTTGGGGGTGCACCTGCTG
CACCGCGCCCTCCTCGTCTTCCTGGCTGAAGGCGAGCGACAGCTTCGTCCCCAGGACATTCAGG
CCCGGGGCTGAGTGCTGGGGAGTTGGCCGTCCAGCCTGGGAAGAAATGTTTGAACGTTCCAGCT
GCCCTGTGCTGACAGCAGCCCCCATCTCTGGTTTCAGAAGGGGTGTGTGTGTGTGTGTGTGTGT
GTGTGTGTGTGTGTGTAGGGAACACCAGGGCAGATCTCCCCCAGTCTGAGAGAGGACTTTGTTA
CAGATGGTACTGCTGGAGGGGTAGTAAGTAGTGAGCTCCCCGTCATGGGAGGAGGACAAGTAGG
GAAGCAGAAGGTGCTTAGGAACAGTCCGGTGCTTCTGTCAGAGGCGTTTGAACCTGGGCAACTC
CACCTTGAATAGGAGCTGGGTAAAATGAGGCTGAAACCTACTGGGCTGC

hide sequence

RefSeq Acc Id:

XM_007995706 ⟹ XP_007993897

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	6	15,788,864 - 15,794,046 (+)	NCBI
Vero_WHO_p1.0	NW_023666074	3,648,148 - 3,653,328 (-)	NCBI

Sequence:

show sequence

AGCAACCCTCCTGCCTGGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGTGCCTGGC
CTAAGCCTCTCATAAGGCCGTGCGCCCTCCCAGAGGCCACCCTTGCAGAAGATTCCCTGAGACT
TAAAGACCTGGGGCACCCCGGACTTTCCTAATCATAGCTCCACCCACTCGAGGCGGGTGCCTTT
GCGTTTCCCGTTTTTAAATGAGATAGTGGCACACCCGGTGGCATCCTCCCGCCCGGGCTCTTAT
CGGCGGTCCCAGCCCTGCTTGAGCGCCTCCGGGTGTCACGGGCCTCTGCGAACACCAAAGCTCT
CGAACCCCGATGTGGACCCCGGTGCGGCGCGGGGCGGCCTGGCTGGGAACCCTGCTCAGCCCCG
GAGAGGGTCCCCACGAGCCGAGGGGCGGAGCGGCGCATGCCCACAAGCCAGCCGCGGGAAGTAG
GAAATCGACCCCCCAGGCGGTGCGCTTCGGACCCCGCCAGGGCATGTGCTCCGAGGCCCTCCTG
GCTCGCAGGTTGCGGGCGGCGCTGCGGGAGGAGGAGCCGTGGGCGGTAGAGGAGCTGCTGCGCT
GCGGCGCGGACCCTAATTTGGTGCTGGAGGATGGCGCAGCTGCTGTGCACTTGGCTGCCGGAGC
CCGGCACCCGCGCGGCCTGCGTTGCCTCGGGGCCCTACTGCGCCAAGGCGGGGACCCCAACGCT
CGATCTGTCGAGGCATTGACACCGCTGCATGTGGCCGCTGCCTGGGGCTGCCGCCGCGGCCTGG
AGCTGCTGCTGAGCCAAGGAGCAAACCCGGCGCTGCGCGACCAGGACGGACTCCGGCCGCTGGA
CCTGGCCCTGCAGCAGGGGCACCTGGAGTGTGCGCGAGTCCTGCAGGATCTCGACACGCGGACC
AGGACCCGGACCCGGATCGGGGCAGAGACCCAGGAGCCCGAGGCTGCACCTGGCACTCCAGGCC
TCTCTGGATCTCCTGATGAGATGCTGGACTCCATAGCACTCCAAACGCAGCCATGCAGAGGTGA
CAACAGGGACACGGGCTTGGAGGCTGACCCAGGAACCCCCAGCCTCCCTGTTCCCCTTGAAATT
GTGGACAAAGATAGGAGCTCAGCGTCCCCTCCAGGGCACTGGGATTACAGCTCAGATGCCTCTT
TCATCACAGCAGTTGAGGTCTCTGGAGCCAAGGACCCAGCCTCGGATACTCCCCCCTGGGCTGG
GTCATTGCCACTGACCAGGCAGGGACTTCTGCATGTTGTCCATGCCACACAGAGGGTACCTAGG
TCTCAGGGGACGGAGGCAGAACTGAATGCCCGTCTGCAGGCCCTGACTCTGACCCCACCAAATG
CTGCTGGCTTCCAGTCCTGCCCTTCCTCCATGCCTCTCCTAGACAGGAGTCCAGCTCACAGCCC
CCCACAGACACCACCCCCTGGAGCTTCTGACTGCCACGGCCTGTGGGAGCACCAGACATCCATT
GATAGTGACATGGCCACGCTCTGGCTGACAGAGGATGAGGCAAGCTCTACAGGTGGCAGAGACC
CTGTCGGCTGTTGCCAGCACCCGCCAGTCTCCATTGTGTCTGACTTGGAGTTGCTGCAGGGGCT
GCGAGCGCTTGGCCCAGAGTTTTCAGGGCACAGCCTAGAACTGGCTGCAGCCCTGCGGACAGGC
TGTATTCCAGATGTCCAGGCAGATGAAGACGCGCTGGCCCAGCAGTTTGAGCAGCCAGATCCTG
CCAGGAGGTGGCGGGAGGGGGTCGTGAAGTCTAGCTTCACATATCTGCTGCTGGACCCCAGGGA
GACTCAGGACCTGCCAGCCCGAGCCTTCTCACTGACCCCAGCTGAGCGCCTTCAGACTTTCGTC
CGTGCCATCTTCTACGTGGGCAAAGGGACGAGGGCCCGGCCATATGTCCACCTCTGGGAAGCCC
TTGGTCACCATGGGCGGTCAAGAAAACAGCCCCCCCAGGCCTGCCCCAAGGTGCGTCAGATCTT
GGACATCTGGGCCAGTGGTTGCGGCGTTGTGTCCCTACATTGCTTCCAGCATGTGGTCGCTGTG
GAGGCTTATACACGGGAGGCGTGTATTGTGGAAGCCCTAGGGATCCAGACGCTCACCAACCAGA
AACAAGGGCACTGCTATGGAGTGGTGGCAGGCTGGCCACCTGCTCGTCGCCGGCGCTTGGGGGT
GCACCTGCTGCACCGCGCCCTCCTCGTCTTCCTGGCTGAAGGCGAGCGACAGCTTCGTCCCCAG
GACATTCAGGCCCGGGGCTGAGTGCTGGGGAGTTGGCCGTCCAGCCTGGGAAGAAATGTTTGAA
CGTTCCAGCTGCCCTGTGCTGACAGCAGCCCCCATCTCTG

hide sequence

RefSeq Acc Id:

XR_005238486

Type:

NON-CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666074	3,633,798 - 3,653,328 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_007993894	(Get FASTA)	NCBI Sequence Viewer
	XP_007993896	(Get FASTA)	NCBI Sequence Viewer
	XP_007993897	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000001943
	ENSCSAP00000001943.1

RefSeq Acc Id:	XP_007993896 ⟸ XM_007995705
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_007993897 ⟸ XM_007995706
- Peptide Label:	isoform X2
- UniProtKB:	A0A0D9R004 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_007993894 ⟸ XM_007995703
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9R004 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCSAP00000001943 ⟸ ENSCSAT00000003670

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000005640	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000003670.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.720.40	UniProtKB/TrEMBL
	1.25.40.20	UniProtKB/TrEMBL
InterPro	ANKLE1	UniProtKB/TrEMBL
	Ankyrin_rpt	UniProtKB/TrEMBL
	Ankyrin_rpt-contain_sf	UniProtKB/TrEMBL
	GIY-YIG_endonuc	UniProtKB/TrEMBL
	LEM/LEM-like_dom_sf	UniProtKB/TrEMBL
	LEM_dom	UniProtKB/TrEMBL
NCBI Gene	ANKLE1	ENTREZGENE
PANTHER	ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 1	UniProtKB/TrEMBL
	PTHR46427	UniProtKB/TrEMBL
Pfam	Ank_2	UniProtKB/TrEMBL
	LEM	UniProtKB/TrEMBL
PROSITE	ANK_REP_REGION	UniProtKB/TrEMBL
	ANK_REPEAT	UniProtKB/TrEMBL
	GIY_YIG	UniProtKB/TrEMBL
	LEM	UniProtKB/TrEMBL
SMART	ANK	UniProtKB/TrEMBL
	LEM	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48403	UniProtKB/TrEMBL
	SSF63451	UniProtKB/TrEMBL
UniProt	A0A0D9R004	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar