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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of macrophage derived foam cell differentiation
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Accession:GO:0010745 term browser browse the term
Definition:Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.


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negative regulation of macrophage derived foam cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca5 ATP binding cassette subfamily A member 5 involved_in ISO (MGI:4454250|PMID:20382126) RGD PMID:20382126 MGI:4454250 NCBI chr10:95,240,159...95,309,195
Ensembl chr10:95,240,154...95,308,976 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISO
ISS		 (PMID:11222466)
GO_REF:0000024		 RGD
UniProt		 PMID:11222466 GO_REF:0000024 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Crp C-reactive protein involved_in ISO (PMID:18322245) RGD PMID:18322245 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Itgav integrin subunit alpha V involved_in ISO (PMID:15215180) RGD PMID:15215180 NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639 		JBrowse link
G Itgb3 integrin subunit beta 3 involved_in ISO
IEA		 (PMID:15215180)
GO_REF:0000107		 RGD
Ensembl		 PMID:15215180 GO_REF:0000107 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G Mir130b microRNA 130b involved_in ISO (PMID:31512787) RGD PMID:31512787 NCBI chr11:83,880,163...83,880,244
Ensembl chr11:83,880,163...83,880,244 		JBrowse link
G Nfkbia NFKB inhibitor alpha involved_in ISO (PMID:16938301) RGD PMID:16938301 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha involved_in ISO (PMID:19114110) RGD PMID:19114110 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO (PMID:19114110) RGD PMID:19114110 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    negative regulation of biological process 5667
      negative regulation of developmental process 1096
        negative regulation of cell differentiation 790
          negative regulation of macrophage derived foam cell differentiation 9
Path 2
Term Annotations click to browse term
  biological_process 19692
    developmental process 6963
      cellular developmental process 4695
        cell differentiation 4694
          foam cell differentiation 31
            macrophage derived foam cell differentiation 30
              regulation of macrophage derived foam cell differentiation 25
                negative regulation of macrophage derived foam cell differentiation 9
paths to the root