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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of macrophage derived foam cell differentiation
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Accession:GO:0010743 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.


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negative regulation of macrophage derived foam cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca5 ATP binding cassette subfamily A member 5 involved_in ISO (PMID:20382126) RGD PMID:20382126 NCBI chr10:95,240,159...95,309,195
Ensembl chr10:95,240,154...95,308,976 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISO
ISS		 (PMID:11222466)
GO_REF:0000024		 RGD
UniProt		 PMID:11222466 GO_REF:0000024 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Crp C-reactive protein involved_in ISO (PMID:18322245) RGD PMID:18322245 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Itgav integrin subunit alpha V involved_in ISO (PMID:15215180) RGD PMID:15215180 NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639 		JBrowse link
G Itgb3 integrin subunit beta 3 involved_in ISO
IEA		 (PMID:15215180)
GO_REF:0000107		 RGD
Ensembl		 PMID:15215180 GO_REF:0000107 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G Mir130b microRNA 130b involved_in ISO (PMID:31512787) RGD PMID:31512787 NCBI chr11:83,880,163...83,880,244
Ensembl chr11:83,880,163...83,880,244 		JBrowse link
G Nfkbia NFKB inhibitor alpha involved_in ISO (PMID:16938301) RGD PMID:16938301 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha involved_in ISO (PMID:19114110) RGD PMID:19114110 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO (PMID:19114110) RGD PMID:19114110 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
positive regulation of macrophage derived foam cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen involved_in ISO
IEA		 (PMID:18971559)
GO_REF:0000107		 RGD
Ensembl		 PMID:18971559 GO_REF:0000107 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a involved_in ISO (PMID:18971559) RGD PMID:18971559 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Alox15b arachidonate 15-lipoxygenase, type B involved_in ISO
IEA		 (PMID:22912809)
GO_REF:0000107		 RGD
Ensembl		 PMID:22912809 GO_REF:0000107 NCBI chr10:53,892,496...53,901,812
Ensembl chr10:53,892,466...53,901,812 		JBrowse link
G Apob apolipoprotein B involved_in ISO
IEA		 (PMID:17244792), (PMID:18322245), (PMID:19114110)
GO_REF:0000107		 RGD
Ensembl		 PMID:17244792 PMID:18322245 PMID:19114110 GO_REF:0000107 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497 		JBrowse link
G Cd36 CD36 molecule involved_in ISO
IEA		 (PMID:10772654)
GO_REF:0000107
(PMID:10772654), (PMID:12376530)		 RGD
Ensembl		 PMID:10772654 PMID:12376530 GO_REF:0000107 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Csf1 colony stimulating factor 1 involved_in ISO
IEA		 (PMID:17244792)
GO_REF:0000107		 RGD
Ensembl		 PMID:17244792 GO_REF:0000107 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704 		JBrowse link
G Csf2 colony stimulating factor 2 involved_in ISO (PMID:19032770) RGD PMID:19032770 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Il18 interleukin 18 involved_in IEA
ISO		 GO_REF:0000107
(PMID:12829194)		 Ensembl
RGD		 PMID:12829194 GO_REF:0000107 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Lpl lipoprotein lipase involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P35951 (PMID:10858435)		 Ensembl
RGD		 PMID:10858435 GO_REF:0000107 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 involved_in ISO
IEA		 (PMID:18262097)
GO_REF:0000107		 RGD
Ensembl		 PMID:18262097 GO_REF:0000107 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Mir185 microRNA 185 involved_in ISO (PMID:26523989) RGD PMID:26523989 NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795 		JBrowse link
G Msr1 macrophage scavenger receptor 1 involved_in ISO UniProtKB:Q08857 (PMID:12376530) RGD PMID:12376530 NCBI chr16:52,717,775...52,803,602
Ensembl chr16:52,717,732...52,799,676 		JBrowse link
G Pf4 platelet factor 4 involved_in ISO (PMID:17244792) RGD PMID:17244792 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365 		JBrowse link
G Pla2g3 phospholipase A2, group III involved_in ISO (PMID:18801741) RGD PMID:18801741 NCBI chr14:78,367,625...78,373,913
Ensembl chr14:78,368,105...78,373,913 		JBrowse link
G Pla2g5 phospholipase A2, group V involved_in ISS
ISO		 GO_REF:0000024
(PMID:14962950)		 UniProt
RGD		 PMID:14962950 GO_REF:0000024 NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658 		JBrowse link
G Prkch protein kinase C, eta involved_in ISS
ISO		 GO_REF:0000024
(PMID:20558593)		 UniProt
RGD		 PMID:20558593 GO_REF:0000024 NCBI chr 6:92,292,000...92,490,663
Ensembl chr 6:92,292,000...92,490,654 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20075
    developmental process 7069
      regulation of developmental process 2763
        regulation of cell differentiation 1783
          regulation of macrophage derived foam cell differentiation 25
            negative regulation of macrophage derived foam cell differentiation 9
            positive regulation of macrophage derived foam cell differentiation 16
Path 2
Term Annotations click to browse term
  biological_process 20075
    developmental process 7069
      cellular developmental process 4781
        cell differentiation 4780
          foam cell differentiation 29
            macrophage derived foam cell differentiation 28
              regulation of macrophage derived foam cell differentiation 25
                negative regulation of macrophage derived foam cell differentiation 9
                positive regulation of macrophage derived foam cell differentiation 16
paths to the root