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ABC-type xenobiotic transporter activity - Ontology Report - Rat Genome Database

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ONTOLOGY REPORT - ANNOTATIONS


Term:ABC-type xenobiotic transporter activity
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Accession:GO:0008559 term browser browse the term
Definition:Catalysis of the reaction: ATP + H2O + xenobiotic(in) = ADP + phosphate + xenobiotic(out).
Synonyms:exact_synonym: ATP-dependent xenobiotic transmembrane transporter activity;   xenobiotic transmembrane transporting ATPase activity
 narrow_synonym: xenobiotic ABC transporter
 related_synonym: ATP phosphohydrolase (xenobiotic-exporting);   ATPase-coupled xenobiotic transmembrane transporter activity;   MDR protein;   P-glycoprotein;   PDR protein;   multidrug resistance exporter;   multidrug-resistance protein;   pleiotropic-drug-resistance protein
 alt_id: GO:0005226;   GO:0008560
 xref: EC:7.6.2.2;   MetaCyc:3.6.3.44-RXN;   Reactome:R-HSA-9757139 "ABCB1,ABCC2 transport ATVs from cytosol to extracellular region"


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ABC-type xenobiotic transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca3 ATP binding cassette subfamily A member 3 enables ISS
ISO
IEA
GO_REF:0000024
(PMID:26903515)
GO_REF:0000003
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:26903515 GO_REF:0000003 GO_REF:0000024 GO_REF:0000107 NCBI chr10:13,886,948...13,944,286
Ensembl chr10:13,382,540...13,439,745
JBrowse link
G Abca8 ATP binding cassette subfamily A member 8 enables ISO (PMID:12379217) RGD PMID:12379217 NCBI chr10:95,416,984...95,490,647
Ensembl chr10:94,917,520...94,990,988
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 enables ISO
ISS
IMP
(PMID:18245269)
GO_REF:0000024
RGD
UniProt
PMID:18245269 PMID:18245269 GO_REF:0000024, RGD:30309924 NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A enables ISO
IEA
RNAcentral:URS000021202F_9606|RNAcentral:URS00003496BE_9606 (PMID:23893241), (PMID:26850595), (PMID:28260112), (PMID:28411377), (PMID:28757552)
GO_REF:0000107
RGD
Ensembl
PMID:23893241 PMID:26850595 PMID:28260112 PMID:28411377 PMID:28757552 GO_REF:0000107 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B enables IEA GO_REF:0000003
GO_REF:0000107
UniProt
Ensembl
GO_REF:0000003 GO_REF:0000107 NCBI chr 4:26,197,706...26,280,156
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 enables IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 4:26,106,895...26,164,440
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 enables IDA
IMP
IBA
IEA
estrone 3-sulfate transport
GO_REF:0000033
GO_REF:0000116
GO_REF:0000003
GO_Central
RHEA
UniProt
RGD
PMID:12867490 PMID:12893836 GO_REF:0000003 GO_REF:0000033 GO_REF:0000116, RGD:2303048, RGD:2303061 NCBI chr10:1,022,041...1,162,431
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc10 ATP binding cassette subfamily C member 10 enables ISO
IEA
(PMID:23087055)
GO_REF:0000107
RGD
Ensembl
PMID:23087055 GO_REF:0000107 NCBI chr 9:22,154,811...22,174,743
Ensembl chr 9:14,657,264...14,677,178
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 enables ISO
IMP
IEA
(PMID:10220572), (PMID:18245269)
GO_REF:0000107
GO_REF:0000003
RGD
Ensembl
UniProt
PMID:10220572 PMID:18245269 PMID:10220572 GO_REF:0000003 GO_REF:0000107, RGD:42721988 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 enables IEA
ISO
GO_REF:0000107
(PMID:11581266), (PMID:18245269), (PMID:19334674)
GO_REF:0000003
Ensembl
RGD
UniProt
PMID:11581266 PMID:18245269 PMID:19334674 GO_REF:0000003 GO_REF:0000107 NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr15:101,948,387...102,182,912
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 enables ISO
ISS
IEA
(PMID:12695538), (PMID:15899835)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:12695538 PMID:15899835 GO_REF:0000024 GO_REF:0000107 NCBI chr11:93,975,579...94,071,659
Ensembl chr11:80,473,872...80,567,253
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 enables IDA PMID:10692506 UniProt PMID:10692506 RGD:1549867 NCBI chr 1:105,583,681...105,637,895
Ensembl chr 1:96,447,251...96,501,464
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 enables ISO
IEA
(PMID:9861027)
GO_REF:0000003
RGD
UniProt
PMID:9861027 GO_REF:0000003 NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Ralbp1 ralA binding protein 1 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 9:112,903,289...112,940,093
Ensembl chr 9:105,456,425...105,492,707
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21102
    transporter activity 1395
      transmembrane transporter activity 1278
        xenobiotic transmembrane transporter activity 32
          ABC-type xenobiotic transporter activity 15
            ABC-type bacteriocin transporter activity 0
Path 2
Term Annotations click to browse term
  molecular_function 21102
    transporter activity 1395
      transmembrane transporter activity 1278
        active transmembrane transporter activity 449
          primary active transmembrane transporter activity 168
            ATPase-coupled transmembrane transporter activity 119
              ABC-type transporter activity 56
                ABC-type xenobiotic transporter activity 15
                  ABC-type bacteriocin transporter activity 0
paths to the root