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ONTOLOGY REPORT - ANNOTATIONS

Term:ABC-type xenobiotic transporter activity
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Accession:GO:0008559 term browser browse the term
Definition:Catalysis of the reaction: ATP + H2O + xenobiotic(in) = ADP + phosphate + xenobiotic(out).
Synonyms:exact_synonym: ATP-dependent xenobiotic transmembrane transporter activity;   xenobiotic transmembrane transporting ATPase activity
 narrow_synonym: xenobiotic ABC transporter
 related_synonym: ATP phosphohydrolase (xenobiotic-exporting);   ATPase-coupled xenobiotic transmembrane transporter activity;   MDR protein;   P-glycoprotein;   PDR protein;   multidrug resistance exporter;   multidrug-resistance protein;   pleiotropic-drug-resistance protein
 alt_id: GO:0005226;   GO:0008560
 xref: EC:7.6.2.2;   MetaCyc:3.6.3.44-RXN;   Reactome:R-HSA-9757139 "ABCB1,ABCC2 transport ATVs from cytosol to extracellular region"


show annotations for term's descendants           Sort by:
ABC-type xenobiotic transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca3 ATP binding cassette subfamily A member 3 enables ISS
ISO		 GO_REF:0000024
(PMID:26903515)		 UniProt
RGD		 PMID:26903515 GO_REF:0000024 NCBI chr10:13,382,439...13,439,748
Ensembl chr10:13,382,540...13,439,745 		JBrowse link
G Abca8 ATP binding cassette subfamily A member 8 enables ISO (PMID:12379217) RGD PMID:12379217 NCBI chr10:94,917,520...94,991,199
Ensembl chr10:94,917,520...94,990,988 		JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 enables IEA
ISO
ISS
IMP		 GO_REF:0000107
(PMID:18245269)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:18245269 PMID:18245269 GO_REF:0000024 GO_REF:0000107, RGD:30309924 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A enables ISO RNAcentral:URS000021202F_9606|RNAcentral:URS00003496BE_9606 (PMID:23893241), (PMID:26850595), (PMID:28260112), (PMID:28411377), (PMID:28757552) RGD PMID:23893241 PMID:26850595 PMID:28260112 PMID:28411377 PMID:28757552 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 enables IDA
IMP
IBA		 estrone 3-sulfate transport
GO_REF:0000033		 GO_Central
RGD		 PMID:12867490 PMID:12893836 GO_REF:0000033, RGD:2303048, RGD:2303061 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Abcc10 ATP binding cassette subfamily C member 10 enables ISO (PMID:23087055) RGD PMID:23087055 NCBI chr 9:14,657,242...14,677,178
Ensembl chr 9:14,657,264...14,677,178 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 enables ISO
IMP
IEA		 (PMID:10220572), (PMID:18245269)
GO_REF:0000107		 RGD
Ensembl		 PMID:10220572 PMID:18245269 PMID:10220572 GO_REF:0000107, RGD:42721988 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 enables IEA
ISO		 GO_REF:0000107
(PMID:11581266), (PMID:18245269), (PMID:19334674)		 Ensembl
RGD		 PMID:11581266 PMID:18245269 PMID:19334674 GO_REF:0000107 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283 		JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 enables ISO
ISS
IEA		 (PMID:12695538), (PMID:15899835)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:12695538 PMID:15899835 GO_REF:0000024 GO_REF:0000107 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253 		JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 enables IDA PMID:10692506 UniProt PMID:10692506 RGD:1549867 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 enables ISO (PMID:9861027) RGD PMID:9861027 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Ralbp1 ralA binding protein 1 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 9:105,456,425...105,493,235
Ensembl chr 9:105,456,425...105,492,707 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20483
    transporter activity 1237
      transmembrane transporter activity 1143
        xenobiotic transmembrane transporter activity 31
          ABC-type xenobiotic transporter activity 14
            ABC-type bacteriocin transporter activity 0
Path 2
Term Annotations click to browse term
  molecular_function 20483
    transporter activity 1237
      transmembrane transporter activity 1143
        active transmembrane transporter activity 444
          primary active transmembrane transporter activity 152
            ATPase-coupled transmembrane transporter activity 117
              ABC-type transporter activity 55
                ABC-type xenobiotic transporter activity 14
                  ABC-type bacteriocin transporter activity 0
paths to the root