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Term:
Parent Terms Term With Siblings Child Terms
ATP hydrolysis activity  
ATP-dependent activity, acting on DNA +   
ATP-dependent activity, acting on RNA +   
ATP-dependent DNA/DNA annealing activity  
ATP-dependent FeS chaperone activity  
ATP-dependent peptidase activity  
ATP-dependent protein disaggregase activity  
ATP-dependent protein folding chaperone  
ATPase-coupled intramembrane lipid transporter activity +   
ATPase-coupled transmembrane transporter activity +   
Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source.
calcium-dependent ATPase activity  
clathrin-uncoating ATPase activity  
decarboxylation-driven active transmembrane transporter activity +  
diphosphate hydrolysis-driven proton transmembrane transporter activity 
fatty acid ligase activity +   
helicase activity +   
membrane protein dislocase activity  
methyl transfer-driven active transmembrane transporter activity 
microfilament motor activity +   
microtubule motor activity +   
microtubule severing ATPase activity  
oxidoreduction-driven active transmembrane transporter activity +   
proteasome-activating activity  
tubulin-dependent ATPase activity  
ubiquitin-like modifier activating enzyme activity +   

Synonyms
Exact Synonyms: ATP-coupled transmembrane transporter activity ;   ATP-dependent transmembrane transporter activity ;   ATPase activity, coupled to transmembrane movement of substances
Narrow Synonyms: hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
Broad Synonyms: ATPase activity, coupled to movement of substances ;   P-P-bond-hydrolysis-driven transmembrane transporter activity ;   P-P-bond-hydrolysis-driven transporter
Alternate IDs: GO:0015405 ;   GO:0016820 ;   GO:0043492
Xrefs: EC:7.2.2.- ;   Reactome:R-HSA-1467457 "ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region" ;   Reactome:R-HSA-2161506 "abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate" ;   Reactome:R-HSA-2161538 "abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate" ;   Reactome:R-HSA-9033499 "PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol" ;   Reactome:R-HSA-9033505 "PEX1:PEX6:PEX26:ZFAND6:Ub:PEX5S,L:PEX14:PEX13:PEX2:PEX10:PEX12 dissociates yielding cytosolic Ub:PEX5S,L and membrane PEX14:PEX13:PEX2:PEX10:PEX12" ;   Reactome:R-HSA-9659680 "ABCB1 transports xenobiotics out of the cell" ;   Reactome:R-HSA-9750546 "ABCC4 transports TPMP substrates from cytosol to extracellular region" ;   Reactome:R-HSA-9750617 "ABCC5 transports TPMP substrates from cytosol to extracellular region" ;   Reactome:R-HSA-9753278 "ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3" ;   Reactome:R-HSA-9753283 "ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3" ;   Reactome:R-HSA-9753284 "ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region" ;   Reactome:R-HSA-9759454 "ABCB1 transports PREDN,PREDL out of kidney cells" ;   Reactome:R-HSA-9759461 "ABCB1 transports PREDN,PREDL out of hepatic cells" ;   Reactome:R-HSA-9794120 "ABCG2 transports Cipro from intestinal cell to extracellular space" ;   Reactome:R-HSA-9794572 "ABCG2 transports Cipro from hepatic cell to extracellular space"
Definition Sources: GOC:mtg_transport, ISBN:0815340729

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