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ONTOLOGY REPORT - ANNOTATIONS

Term:endochondral ossification
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Accession:GO:0001958 term browser browse the term
Definition:Replacement ossification wherein bone tissue replaces cartilage.
Synonyms:xref: Wikipedia:Endochondral_ossification


show annotations for term's descendants           Sort by:
endochondral ossification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALPL alkaline phosphatase, biomineralization associated involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20684022) Ensembl
MGI		 PMID:20684022 GO_REF:0000107 NCBI chr 1:20,702,509...20,772,301
Ensembl chr 1:21,667,732...21,736,688 		JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752 		JBrowse link
G BMP6 bone morphogenetic protein 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9664685) Ensembl
MGI		 PMID:9664685 GO_REF:0000107 NCBI chr 6:7,564,164...7,720,341
Ensembl chr 6:7,848,249...8,000,649 		JBrowse link
G BPNT2 3'(2'), 5'-bisphosphate nucleotidase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18539921) Ensembl
MGI		 PMID:18539921 GO_REF:0000107 NCBI chr 8:53,385,837...53,417,019
Ensembl chr 8:50,753,792...50,785,055 		JBrowse link
G CBS cystathionine beta-synthase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15622513) Ensembl
MGI		 PMID:15622513 GO_REF:0000107 NCBI chr21:29,361,519...29,385,610
Ensembl chr21:42,670,530...42,690,932 		JBrowse link
G COL10A1 collagen type X alpha 1 chain ISO RGD PMID:10853827 RGD:704421 NCBI chr 6:113,921,538...113,961,490
Ensembl chr 6:118,067,477...118,074,684 		JBrowse link
G COL1A1 collagen type I alpha 1 chain involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8130375) Ensembl
MGI		 PMID:8130375 GO_REF:0000107 NCBI chr17:44,274,349...44,291,764
Ensembl chr17:49,150,677...49,166,677 		JBrowse link
G COL2A1 collagen type II alpha 1 chain acts_upstream_of_or_within ISO (PMID:10100048) MGI PMID:10100048 NCBI chr12:40,726,137...40,757,690 JBrowse link
G CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21148564) Ensembl
MGI		 PMID:21148564 GO_REF:0000107 NCBI chr 8:18,626,998...18,980,416
Ensembl chr 8:15,576,416...15,904,123 		JBrowse link
G CST5 cystatin D involved_in ISO (PMID:16680148) MGI PMID:16680148 NCBI chr20:23,824,663...23,828,483
Ensembl chr20:24,178,197...24,182,016 		JBrowse link
G DLX5 distal-less homeobox 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:88,972,066...88,977,588
Ensembl chr 7:102,555,267...102,561,186 		JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO (PMID:24770645) MGI PMID:24770645 NCBI chr 6:129,591,858...129,673,000
Ensembl chr 6:133,698,640...133,783,644 		JBrowse link
G EXT1 exostosin glycosyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21185280), (PMID:23958822) Ensembl
MGI		 PMID:21185280 PMID:23958822 GO_REF:0000107 NCBI chr 8:114,489,325...114,803,763
Ensembl chr 8:117,011,919...117,324,851 		JBrowse link
G FGF18 fibroblast growth factor 18 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17014841) Ensembl
MGI		 PMID:17014841 GO_REF:0000107 NCBI chr 5:166,765,061...166,802,277 JBrowse link
G FOXC1 forkhead box C1 involved_in ISO (PMID:25808752) UniProt PMID:25808752 NCBI chr 6:1,429,051...1,433,180 JBrowse link
G GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 acts_upstream_of_or_within ISO (PMID:25107907) MGI PMID:25107907 NCBI chr2B:53,014,933...53,066,330
Ensembl chr2B:170,335,216...170,539,231 		JBrowse link
G GNAS GNAS complex locus acts_upstream_of_or_within ISO (PMID:15797856) MGI PMID:15797856 NCBI chr20:55,190,607...55,262,245 JBrowse link
G HSPG2 heparan sulfate proteoglycan 2 acts_upstream_of_or_within ISO (PMID:10579729) MGI PMID:10579729 NCBI chr 1:21,014,951...21,129,937
Ensembl chr 1:21,979,504...22,053,400 		JBrowse link
G IFT80 intraflagellar transport 80 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:26098911) Ensembl
MGI		 PMID:26098911 GO_REF:0000107 NCBI chr 3:157,279,076...157,421,478
Ensembl chr 3:165,329,056...165,454,905 		JBrowse link
G INPPL1 inositol polyphosphate phosphatase like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:67,302,066...67,317,785
Ensembl chr11:70,527,017...70,540,846 		JBrowse link
G LOC100973165 collagen alpha-1(XIII) chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:66,277,302...66,434,410
Ensembl chr10:68,807,425...68,963,642 		JBrowse link
G LOC100978090 protein ALEX involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:55,204,188...55,206,608
Ensembl chr20:56,474,459...56,621,747 		JBrowse link
G MEF2C myocyte enhancer factor 2C acts_upstream_of_or_within ISO (PMID:17336904) MGI PMID:17336904 NCBI chr 5:26,480,489...26,650,813
Ensembl chr 5:26,681,700...26,786,426 		JBrowse link
G MEF2D myocyte enhancer factor 2D involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17336904) Ensembl
MGI		 PMID:17336904 GO_REF:0000107 NCBI chr 1:131,806,705...131,844,420
Ensembl chr 1:135,637,801...135,653,866 		JBrowse link
G MMP13 matrix metallopeptidase 13 involved_in ISO
IEA		 RGD
Ensembl		 PMID:10646117 GO_REF:0000107 RGD:10043159 NCBI chr11:97,890,811...97,902,778
Ensembl chr11:101,377,001...101,387,679 		JBrowse link
G MMP14 matrix metallopeptidase 14 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18022611) Ensembl
MGI		 PMID:18022611 GO_REF:0000107 NCBI chr14:3,654,125...3,665,158
Ensembl chr14:21,753,305...21,764,058 		JBrowse link
G MMP16 matrix metallopeptidase 16 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18022611) Ensembl
MGI		 PMID:18022611 GO_REF:0000107 NCBI chr 8:84,736,752...85,026,711
Ensembl chr 8:86,701,882...86,982,518 		JBrowse link
G NAB1 NGFI-A binding protein 1 acts_upstream_of_or_within ISO (PMID:16136673) MGI PMID:16136673 NCBI chr2B:77,949,948...77,994,888
Ensembl chr2B:195,868,102...195,911,497 		JBrowse link
G NAB2 NGFI-A binding protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16136673) Ensembl
MGI		 PMID:16136673 GO_REF:0000107 Ensembl chr12:32,085,031...32,091,498 JBrowse link
G NFIX nuclear factor I X involved_in ISO (PMID:17353270) MGI PMID:17353270 NCBI chr19:12,557,020...12,660,316
Ensembl chr19:13,327,690...13,402,406 		JBrowse link
G NPR2 natriuretic peptide receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:35,642,534...35,660,210
Ensembl chr 9:36,445,576...36,462,637 		JBrowse link
G PEX7 peroxisomal biogenesis factor 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12915479) Ensembl
MGI		 PMID:12915479 GO_REF:0000107 NCBI chr 6:134,582,933...134,675,388
Ensembl chr 6:138,672,179...138,762,830 		JBrowse link
G PHOSPHO1 phosphoethanolamine/phosphocholine phosphatase 1 acts_upstream_of_or_within ISO (PMID:20684022) MGI PMID:20684022 NCBI chr17:8,373,032...8,381,410
Ensembl chr17:8,357,513...8,364,416 		JBrowse link
G PTHLH parathyroid hormone like hormone acts_upstream_of_or_within ISO (PMID:8895385) MGI PMID:8895385 NCBI chr12:58,341,361...58,355,804
Ensembl chr12:60,960,071...60,973,750 		JBrowse link
G RUNX2 RUNX family transcription factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10072783) Ensembl
MGI		 PMID:10072783 GO_REF:0000107 NCBI chr 6:45,003,962...45,133,148
Ensembl chr 6:46,189,432...46,524,389 		JBrowse link
G SCX scleraxis bHLH transcription factor involved_in ISO (PMID:20059955) UniProt PMID:20059955 NCBI chr 8:141,027,765...141,031,194 JBrowse link
G SIK3 SIK family kinase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22318228) Ensembl
MGI		 PMID:22318228 GO_REF:0000107 NCBI chr11:111,680,884...111,932,424
Ensembl chr11:115,613,478...115,730,158 		JBrowse link
G SMPD3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17591962)
(PMID:24505141)
(PMID:21788370)		 Ensembl
MGI		 PMID:17591962 PMID:21788370 PMID:24505141 GO_REF:0000107 NCBI chr16:48,734,664...48,825,241
Ensembl chr16:68,131,905...68,142,871 		JBrowse link
G TEK TEK receptor tyrosine kinase ISO RGD PMID:11735002 RGD:1601509 NCBI chr 9:26,955,339...27,077,809
Ensembl chr 9:27,561,421...27,683,572 		JBrowse link
G TMEM119 transmembrane protein 119 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:106,166,737...106,173,965
Ensembl chr12:109,563,684...109,564,535 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16644
    multicellular organismal process 7306
      ossification 450
        replacement ossification 40
          endochondral ossification 40
Path 2
Term Annotations click to browse term
  biological_process 16644
    developmental process 6645
      anatomical structure development 6234
        multicellular organism development 5006
          system development 4350
            skeletal system development 571
              bone development 257
                bone morphogenesis 120
                  endochondral bone morphogenesis 74
                    endochondral ossification 40
paths to the root