FOXC1 (forkhead box C1) - Rat Genome Database

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Pathways
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Gene: FOXC1 (forkhead box C1) Pan paniscus
Analyze
Symbol: FOXC1
Name: forkhead box C1
RGD ID: 32732569
Description: ENCODES a protein that exhibits DNA binding (ortholog); DNA binding, bending (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); INVOLVED IN apoptotic process involved in outflow tract morphogenesis (ortholog); artery morphogenesis (ortholog); blood vessel development (ortholog); ASSOCIATED WITH alopecia (ortholog); aniridia (ortholog); anterior segment dysgenesis (ortholog); FOUND IN cytosol (ortholog); heterochromatin (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: forkhead box protein C1
RGD Orthologs
Human
Mouse
Rat
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2516,225,162 - 16,229,276 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1612,220,400 - 12,224,482 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v061,429,051 - 1,433,180 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
apoptotic process involved in outflow tract morphogenesis  (ISO)
artery morphogenesis  (ISO)
blood vessel development  (ISO)
blood vessel diameter maintenance  (ISO)
blood vessel remodeling  (ISO)
brain development  (ISO)
camera-type eye development  (ISO)
cardiac muscle cell proliferation  (ISO)
cell migration  (ISO)
cell population proliferation  (ISO)
cellular response to chemokine  (ISO)
cellular response to epidermal growth factor stimulus  (ISO)
cerebellum development  (ISO)
chemokine-mediated signaling pathway  (ISO)
collagen fibril organization  (ISO)
embryonic heart tube development  (ISO)
endochondral ossification  (ISO)
eye development  (ISO)
germ cell migration  (ISO)
glomerular epithelium development  (ISO)
glycosaminoglycan metabolic process  (ISO)
heart development  (ISO)
heart morphogenesis  (ISO)
in utero embryonic development  (ISO)
kidney development  (ISO)
lacrimal gland development  (ISO)
lymph vessel development  (ISO)
maintenance of lens transparency  (ISO)
mesenchymal cell development  (ISO)
mesenchymal cell differentiation  (ISO)
negative regulation of angiogenesis  (ISO)
negative regulation of apoptotic process involved in outflow tract morphogenesis  (ISO)
negative regulation of lymphangiogenesis  (ISO)
negative regulation of mitotic cell cycle  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
neural crest cell development  (ISO)
Notch signaling pathway  (ISO)
odontogenesis of dentin-containing tooth  (ISO)
ossification  (ISO)
ovarian follicle development  (ISO)
paraxial mesoderm formation  (ISO)
positive regulation of DNA-templated transcription  (ISO)
positive regulation of epithelial to mesenchymal transition  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of hematopoietic progenitor cell differentiation  (ISO)
positive regulation of hematopoietic stem cell differentiation  (ISO)
positive regulation of keratinocyte differentiation  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
regulation of DNA-templated transcription  (ISO)
regulation of organ growth  (ISO)
regulation of transcription by RNA polymerase II  (ISO)
skeletal system development  (ISO)
somitogenesis  (ISO)
ureteric bud development  (ISO)
vascular endothelial growth factor receptor signaling pathway  (ISO)
vascular endothelial growth factor signaling pathway  (ISO)
ventricular cardiac muscle tissue morphogenesis  (ISO)

Cellular Component
cytosol  (ISO)
heterochromatin  (ISO)
nucleoplasm  (ISO)
nucleus  (ISO)

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
FOXC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2516,225,162 - 16,229,276 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1612,220,400 - 12,224,482 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v061,429,051 - 1,433,180 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
FOXC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3861,609,915 - 1,613,897 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl61,609,915 - 1,613,897 (+)EnsemblGRCh38hg38GRCh38
GRCh3761,610,150 - 1,614,132 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3661,555,680 - 1,559,131 (+)NCBINCBI36Build 36hg18NCBI36
Build 3461,555,679 - 1,557,341NCBI
Celera62,838,909 - 2,842,360 (+)NCBICelera
Cytogenetic Map6p25.3NCBI
HuRef61,480,597 - 1,483,685 (+)NCBIHuRef
CHM1_161,612,575 - 1,616,026 (+)NCBICHM1_1
T2T-CHM13v2.061,472,916 - 1,476,901 (+)NCBIT2T-CHM13v2.0
Foxc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391331,990,629 - 31,994,618 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1331,990,616 - 31,996,459 (+)EnsemblGRCm39 Ensembl
GRCm381331,806,646 - 31,810,635 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1331,806,633 - 31,812,476 (+)EnsemblGRCm38mm10GRCm38
MGSCv371331,898,515 - 31,902,504 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361331,814,111 - 31,818,100 (+)NCBIMGSCv36mm8
Celera1332,016,470 - 32,020,494 (+)NCBICelera
Cytogenetic Map13A3.2NCBI
cM Map1313.52NCBI
Foxc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81732,840,119 - 32,844,100 (-)NCBIGRCr8
mRatBN7.21732,631,379 - 32,635,361 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1732,633,142 - 32,634,803 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1732,479,163 - 32,483,145 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01734,082,977 - 34,086,959 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01732,474,984 - 32,478,967 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01733,947,501 - 33,951,484 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1733,947,506 - 33,951,484 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01735,833,707 - 35,837,690 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41739,026,186 - 39,030,163 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1732,190,633 - 32,194,475 (-)NCBICelera
Cytogenetic Map17p12NCBI
FOXC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha352,065,990 - 2,069,716 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0352,012,278 - 2,015,999 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl352,012,321 - 2,014,021 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1351,987,281 - 1,991,006 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0352,008,542 - 2,012,243 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0353,344,191 - 3,347,919 (+)NCBIUU_Cfam_GSD_1.0
FOXC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7837,171 - 838,805 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17837,088 - 840,593 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.271,037,165 - 1,039,040 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FOXC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11770,533,048 - 70,536,555 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1770,534,821 - 70,536,476 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660441,552,589 - 1,556,578 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Foxc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475623,060,751 - 23,062,343 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475623,060,065 - 23,062,407 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_034961351 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_034961351   ⟹   XP_034817242
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2516,225,162 - 16,229,276 (+)NCBI
NHGRI_mPanPan1612,220,400 - 12,224,482 (+)NCBI
Mhudiblu_PPA_v061,429,051 - 1,433,180 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034817242 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_034817242   ⟸   XM_034961351


Additional Information

Database Acc Id Source(s)
NCBI Gene FOXC1 ENTREZGENE