IFT80 (intraflagellar transport 80) - Rat Genome Database

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Gene: IFT80 (intraflagellar transport 80) Pan paniscus
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Symbol: IFT80
Name: intraflagellar transport 80
RGD ID: 11705017
Description: INVOLVED IN apoptotic process (ortholog); articular cartilage development (ortholog); bone development (ortholog); ASSOCIATED WITH Asphyxia (ortholog); asphyxiating thoracic dystrophy (ortholog); asphyxiating thoracic dystrophy 1 (ortholog); FOUND IN 9+0 non-motile cilium (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: intraflagellar transport 80 homolog; intraflagellar transport protein 80 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22158,193,564 - 158,335,974 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13158,198,280 - 158,340,492 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03157,279,076 - 157,421,478 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13165,327,511 - 165,469,795 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3165,329,056 - 165,454,905 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
apoptotic process  (IEA,ISO)
articular cartilage development  (IEA,ISO)
bone development  (IEA,ISO)
bone mineralization involved in bone maturation  (IEA,ISO)
bone morphogenesis  (IEA,ISO)
canonical NF-kappaB signal transduction  (IEA,ISO)
cartilage development  (IEA,ISO)
cartilage homeostasis  (IEA,ISO)
cell population proliferation  (IEA,ISO)
chondrocyte differentiation  (IEA,ISO)
cilium assembly  (IEA,ISO)
cilium organization  (IEA,ISO)
endochondral ossification  (IEA,ISO)
establishment or maintenance of cell polarity  (IEA,ISO)
fibroblast growth factor receptor signaling pathway  (IEA,ISO)
gene expression  (IEA,ISO)
growth plate cartilage chondrocyte differentiation  (IEA,ISO)
growth plate cartilage development  (IEA,ISO)
keratinocyte proliferation  (IEA,ISO)
limb development  (IEA,ISO)
multicellular organism growth  (IEA,ISO)
negative regulation of keratinocyte proliferation  (IEA,ISO)
negative regulation of non-canonical Wnt signaling pathway  (IEA,ISO)
non-canonical Wnt signaling pathway  (IEA,ISO)
non-motile cilium assembly  (IEA,ISO)
odontoblast differentiation  (IEA,ISO)
odontogenesis  (IEA,ISO)
ossification  (IEA,ISO)
osteoblast differentiation  (IEA,ISO)
osteoblast proliferation  (IEA,ISO)
osteoclast differentiation  (IEA,ISO)
phosphatidylinositol 3-kinase/protein kinase B signal transduction  (IEA,ISO)
proteasomal protein catabolic process  (IEA,ISO)
protein stabilization  (IEA,ISO)
protein ubiquitination  (IEA,ISO)
receptor localization to non-motile cilium  (IEA,ISO)
response to inositol  (IEA,ISO)
skeletal system development  (IEA,ISO)
smoothened signaling pathway  (IEA,ISO)
spinal cord development  (IEA,ISO)
stem cell differentiation  (IEA,ISO)
stem cell proliferation  (IEA,ISO)
tissue development  (IEA,ISO)
tooth eruption  (IEA,ISO)

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
IFT80
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22158,193,564 - 158,335,974 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13158,198,280 - 158,340,492 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03157,279,076 - 157,421,478 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13165,327,511 - 165,469,795 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3165,329,056 - 165,454,905 (-)Ensemblpanpan1.1panPan2
IFT80
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383160,256,986 - 160,399,225 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3160,256,986 - 160,399,880 (-)EnsemblGRCh38hg38GRCh38
GRCh373159,974,774 - 160,117,013 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363161,457,482 - 161,600,014 (-)NCBINCBI36Build 36hg18NCBI36
Celera3158,396,141 - 158,538,687 (-)NCBICelera
Cytogenetic Map3q25.33NCBI
HuRef3157,373,426 - 157,515,902 (-)NCBIHuRef
CHM1_13159,937,988 - 160,080,209 (-)NCBICHM1_1
T2T-CHM13v2.03163,031,586 - 163,173,837 (-)NCBIT2T-CHM13v2.0
Ift80
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39368,799,832 - 68,911,939 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl368,799,832 - 68,911,892 (-)EnsemblGRCm39 Ensembl
GRCm38368,892,499 - 69,004,680 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl368,892,499 - 69,004,570 (-)EnsemblGRCm38mm10GRCm38
MGSCv37368,696,421 - 68,808,492 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36368,980,431 - 69,092,394 (-)NCBIMGSCv36mm8
Celera369,005,128 - 69,112,374 (-)NCBICelera
Cytogenetic Map3E1NCBI
cM Map332.07NCBI
Ift80
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82155,455,773 - 155,550,082 (-)NCBIGRCr8
mRatBN7.22153,144,707 - 153,240,024 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2153,145,795 - 153,240,024 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2160,275,443 - 160,369,696 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02158,325,966 - 158,420,213 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02152,958,736 - 153,052,980 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02165,506,878 - 165,600,748 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2165,505,810 - 165,600,748 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02184,867,651 - 184,961,866 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42158,892,673 - 158,987,059 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12158,842,636 - 158,937,022 (-)NCBI
Celera2147,496,487 - 147,590,825 (-)NCBICelera
Cytogenetic Map2q32NCBI
Ift80
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495544810,808,940 - 10,819,655 (-)NCBIChiLan1.0ChiLan1.0
IFT80
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13426,332,456 - 26,455,428 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3430,374,586 - 30,497,664 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03426,388,720 - 26,512,021 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3426,387,471 - 26,511,904 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13426,318,615 - 26,441,864 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03426,279,456 - 26,402,532 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03426,519,525 - 26,642,618 (-)NCBIUU_Cfam_GSD_1.0
Ift80
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560292,197,246 - 92,324,932 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936708238,268 - 362,519 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936708238,302 - 362,537 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IFT80
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1399,943,208 - 100,078,148 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11399,943,203 - 100,078,148 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213108,339,643 - 108,382,860 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IFT80
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11530,441,724 - 30,577,437 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1530,461,526 - 30,577,484 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660412,961,984 - 3,104,898 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ift80
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473038,003,902 - 38,144,277 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473038,003,437 - 38,144,312 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000060977   ⟹   ENSPPAP00000038074
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl3165,329,056 - 165,454,905 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000060979   ⟹   ENSPPAP00000038076
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl3165,329,070 - 165,454,905 (-)Ensembl
RefSeq Acc Id: XM_055110634   ⟹   XP_054966609
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22158,193,564 - 158,335,974 (-)NCBI
NHGRI_mPanPan13158,198,280 - 158,340,492 (-)NCBI
RefSeq Acc Id: XM_055110635   ⟹   XP_054966610
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22158,193,564 - 158,335,974 (-)NCBI
NHGRI_mPanPan13158,198,280 - 158,340,492 (-)NCBI
Protein Sequences
Protein RefSeqs XP_054966609 (Get FASTA)   NCBI Sequence Viewer  
  XP_054966610 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000038074.1
  ENSPPAP00000038076.1
Ensembl Acc Id: ENSPPAP00000038076   ⟸   ENSPPAT00000060979
Ensembl Acc Id: ENSPPAP00000038074   ⟸   ENSPPAT00000060977
RefSeq Acc Id: XP_054966610   ⟸   XM_055110635
- Peptide Label: isoform X2
- UniProtKB: A0A2R9C813 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054966609   ⟸   XM_055110634
- Peptide Label: isoform X1
- UniProtKB: A0A2R9C813 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000041744 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000060977.1 UniProtKB/TrEMBL
  ENSPPAT00000060979.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.470 UniProtKB/TrEMBL
  2.130.10.10 UniProtKB/TrEMBL
InterPro WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
NCBI Gene IFT80 ENTREZGENE
PANTHER INTRAFLAGELLAR TRANSPORT PROTEIN 80 HOMOLOG UniProtKB/TrEMBL
  OUTER SEGMENT 5 UniProtKB/TrEMBL
Pfam WD40 UniProtKB/TrEMBL
PROSITE WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt A0A2R9C813 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9C8C4_PANPA UniProtKB/TrEMBL