CST5 (cystatin D) - Rat Genome Database

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Gene: CST5 (cystatin D) Pan paniscus
Analyze
Symbol: CST5
Name: cystatin D
RGD ID: 11694981
Description: ENCODES a protein that exhibits cysteine-type endopeptidase inhibitor activity (inferred); INVOLVED IN bone mineralization (ortholog); bone morphogenesis (ortholog); calcium ion homeostasis (ortholog); ASSOCIATED WITH familial hyperinsulinemic hypoglycemia 1 (ortholog); FOUND IN cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cystatin-D
RGD Orthologs
Human
Mouse
Rat
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22124,756,245 - 24,760,063 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12024,753,078 - 24,756,896 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02023,824,663 - 23,828,483 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12024,178,197 - 24,182,009 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2024,178,197 - 24,182,016 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CST5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22124,756,245 - 24,760,063 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12024,753,078 - 24,756,896 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02023,824,663 - 23,828,483 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12024,178,197 - 24,182,009 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2024,178,197 - 24,182,016 (-)Ensemblpanpan1.1panPan2
CST5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382023,875,934 - 23,879,748 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2023,875,934 - 23,879,748 (-)EnsemblGRCh38hg38GRCh38
GRCh372023,856,571 - 23,860,385 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362023,804,572 - 23,808,380 (-)NCBINCBI36Build 36hg18NCBI36
Build 342023,804,792 - 23,808,371NCBI
Celera2023,929,951 - 23,933,759 (-)NCBICelera
Cytogenetic Map20p11.21NCBI
HuRef2023,813,604 - 23,817,412 (-)NCBIHuRef
CHM1_12023,856,749 - 23,860,557 (-)NCBICHM1_1
T2T-CHM13v2.02023,935,655 - 23,939,469 (-)NCBIT2T-CHM13v2.0
Cst5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392149,247,242 - 149,252,217 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2149,246,977 - 149,252,213 (+)EnsemblGRCm39 Ensembl
GRCm382149,405,249 - 149,410,278 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2149,405,057 - 149,410,293 (+)EnsemblGRCm38mm10GRCm38
MGSCv372149,230,985 - 149,236,014 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362149,096,690 - 149,101,719 (+)NCBIMGSCv36mm8
Celera2150,661,381 - 150,663,520 (+)NCBICelera
Cytogenetic Map2G3NCBI
cM Map273.8NCBI
Cst5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83158,033,791 - 158,038,345 (+)NCBIGRCr8
mRatBN7.23137,573,194 - 137,577,754 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3137,573,194 - 137,577,754 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3141,505,992 - 141,510,482 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03150,089,686 - 150,094,176 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03147,806,172 - 147,810,725 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03144,569,502 - 144,574,112 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3144,569,502 - 144,574,112 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03150,943,493 - 150,948,103 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43138,967,434 - 138,972,106 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13138,873,315 - 139,339,652 (+)NCBI
Celera3136,259,691 - 136,264,235 (+)NCBICelera
Cytogenetic Map3q41NCBI
CST5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1253,015,431 - 53,020,125 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl253,015,687 - 53,019,336 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605092,820,941 - 92,824,956 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003829361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSPPAT00000037294   ⟹   ENSPPAP00000014607
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2024,178,197 - 24,182,016 (-)Ensembl
RefSeq Acc Id: XM_003829361   ⟹   XP_003829409
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22124,756,245 - 24,760,063 (-)NCBI
NHGRI_mPanPan12024,753,078 - 24,756,896 (-)NCBI
Mhudiblu_PPA_v02023,824,663 - 23,828,483 (-)NCBI
PanPan1.12024,178,197 - 24,182,009 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003829409 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000014607
  ENSPPAP00000014607.1
RefSeq Acc Id: XP_003829409   ⟸   XM_003829361
- UniProtKB: A0A2R9AH53 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000014607   ⟸   ENSPPAT00000037294
Protein Domains
Cystatin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000030471 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000037294.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.450.10 UniProtKB/TrEMBL
InterPro Cystatin_dom UniProtKB/TrEMBL
  Cystatin_sf UniProtKB/TrEMBL
  Prot_inh_cystat_CS UniProtKB/TrEMBL
KEGG Report pps:100992748 UniProtKB/TrEMBL
NCBI Gene CST5 ENTREZGENE
PANTHER CYSTATIN UniProtKB/TrEMBL
  CYSTATIN-D UniProtKB/TrEMBL
Pfam Cystatin UniProtKB/TrEMBL
PROSITE CYSTATIN UniProtKB/TrEMBL
SMART SM00043 UniProtKB/TrEMBL
Superfamily-SCOP SSF54403 UniProtKB/TrEMBL
UniProt A0A2R9AH53 ENTREZGENE, UniProtKB/TrEMBL