RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: Hantavirus Infections
Accession: DOID:9007533
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Definition: Infections with viruses of the genus HANTAVIRUS. This is associated with at least four clinical syndromes: HEMORRHAGIC FEVER WITH RENAL SYNDROME caused by viruses of the Hantaan group; a milder form of HFRS caused by SEOUL VIRUS; nephropathia epidemica caused by PUUMALA VIRUS; and HANTAVIRUS PULMONARY SYNDROME caused by SIN NOMBRE VIRUS.
Synonyms: exact_synonym: Hantavirus Infection; Hantavirus infectious disease
primary_id: MESH:D018778 ; RDO:0005767
xref: EFO:0007295
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Itgb3
integrin subunit beta 3
ISO
RGD
PMID:15886525
RGD:6907410
NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
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Mki67
marker of proliferation Ki-67
ISO
RGD
PMID:21795350
RGD:6483519
NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
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Alb
albumin
severity
ISO
RGD
PMID:14555823
RGD:11035280
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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Apoc3
apolipoprotein C3
disease_progression
ISO
RGD
PMID:20797315
RGD:7207210
NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
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Cd163
CD163 molecule
exacerbates
ISO
protein:increased expression:blood plasma (human) protein:increased expression:CD14-positive, CD16-positive monocyte, blood plasma (human) protein:increased expression:CD14-positive monocyte (human)
RGD
PMID:25789628 PMID:25392926 PMID:29857122
RGD:127285679 , RGD:127345131 , RGD:127285683
NCBI chr 4:157,085,080...157,118,470
Ensembl chr 4:157,085,093...157,117,878
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Ifng
interferon gamma
severity
ISO
protein:increased expression:serum
RGD
PMID:22613426
RGD:6893374
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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Il1rl1
interleukin 1 receptor-like 1
severity
ISO
RGD
PMID:25658420
RGD:40400702
NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256
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Il2ra
interleukin 2 receptor subunit alpha
ISO
protein:increased expression:T cell
RGD
PMID:21436245
RGD:5147436
NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
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Il33
interleukin 33
severity
ISO
RGD
PMID:25658420
RGD:40400702
NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
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Itgb3
integrin subunit beta 3
severity
ISO
protein:increased expression:platelet
RGD
PMID:18419255
RGD:6907404
NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
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RT1-Db1
RT1 class II, locus Db1
susceptibility
ISO
DNA:polymorphism:cds:HLA-DRB1*0401-0411, HLA-DRB1*1001, HLA-DRB1*1101-1105, HLA-DRB1*1201-1202 and HLA-DRB1*1305 (human)
RGD
PMID:25169964
RGD:40818303
NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
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Foxp3
forkhead box P3
IEP
mRNA:increased expression:lung
RGD
PMID:17878294
RGD:2325989
NCBI chr X:14,908,494...14,924,994
Ensembl chr X:14,908,494...14,923,838
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Il2ra
interleukin 2 receptor subunit alpha
treatment
IMP
RGD
PMID:17878294
RGD:2325989
NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
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