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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Hantavirus hemorrhagic fever with renal syndrome
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Accession:DOID:11266 term browser browse the term
Definition:A viral infectious disease that is a hemorrhagic fever, located in kidney, has_material_basis_in Hantaan virus, has_material_basis_in Dobrava-Belgrade orthohantavirus has_material_basis_in Seoul virus, or has_material_basis_in Puumala virus, which are carried and transmitted by rodents. The infection has symptom headache, has symptom fever, has symptom muscle pains, has symptom facial flush, has symptom petechiae, has symptom proteinuria, and has symptom renal failure. (DO)
Synonyms:exact_synonym: HFRS;   Puumala virus nephropathy;   Russian hemorrhagic fever;   epidemic hemorrhagic fever;   epidemic hemorrhagic fevers;   hemorrhagic fever with renal syndrome;   hemorrhagic nephroso nephritis;   hemorrhagic nephroso-nephritides;   hemorrhagic nephrosonephritis
 primary_id: MESH:D006480
 xref: EFO:0007299;   ICD10CM:A98.5;   ICD9CM:078.6;   NCI:C84753
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
Hantavirus hemorrhagic fever with renal syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin severity ISO RGD PMID:14555823 RGD:11035280 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Apoc3 apolipoprotein C3 disease_progression ISO RGD PMID:20797315 RGD:7207210 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583 		JBrowse link
G Cd163 CD163 molecule exacerbates ISO protein:increased expression:CD14-positive, CD16-positive monocyte, blood plasma (human)
protein:increased expression:blood plasma (human)
protein:increased expression:CD14-positive monocyte (human)		 RGD PMID:25392926 PMID:25789628 PMID:29857122 RGD:127345131, RGD:127285679, RGD:127285683 NCBI chr 4:157,085,080...157,118,470
Ensembl chr 4:157,085,093...157,117,878 		JBrowse link
G Ifng interferon gamma severity ISO protein:increased expression:serum RGD PMID:22613426 RGD:6893374 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 severity ISO RGD PMID:25658420 RGD:40400702 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha ISO protein:increased expression:T cell RGD PMID:21436245 RGD:5147436 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697 		JBrowse link
G Il33 interleukin 33 severity ISO RGD PMID:25658420 RGD:40400702 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Itgb3 integrin subunit beta 3 severity ISO protein:increased expression:platelet RGD PMID:18419255 RGD:6907404 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 susceptibility ISO DNA:polymorphism:cds:HLA-DRB1*0401-0411, HLA-DRB1*1001, HLA-DRB1*1101-1105, HLA-DRB1*1201-1202 and HLA-DRB1*1305 (human) RGD PMID:25169964 RGD:40818303 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258 		JBrowse link
Korean hemorrhagic fever term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 IEP mRNA:increased expression:lung RGD PMID:17878294 RGD:2325989 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha treatment IMP RGD PMID:17878294 RGD:2325989 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 20988
    syndrome 10788
      Hantavirus hemorrhagic fever with renal syndrome 10
        Balkan hemorrhagic fever 0
        Hantavirosis 0
        Korean hemorrhagic fever 2
        nephropathia epidemica 0
        polyomavirus-associated nephropathy 0
Path 2
Term Annotations click to browse term
  disease 20988
    disease by infectious agent 2263
      viral infectious disease 1733
        RNA Virus Infections 1386
          Bunyaviridae Infections 14
            Hantavirus Infections 11
              Hantavirus hemorrhagic fever with renal syndrome 10
                Balkan hemorrhagic fever 0
                Hantavirosis 0
                Korean hemorrhagic fever 2
                nephropathia epidemica 0
                polyomavirus-associated nephropathy 0
paths to the root