The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
An extended flavonoid that consists of a pyranochromane skeleton that is 2H,6H-pyrano[3,2-g]chromen-6-one substituted by geminal methyl groups at position 2, a 2,4-dihydroxyphenyl group at position 8, a hydroxy group at position 5 and a prenyl group at position 7. Isolated from Morus alba and Morus species it exhibits anti-inflammatory activity.
cudraflavone B results in increased expression of BAX protein resveratrol inhibits the reaction [cudraflavone B results in increased expression of BAX protein]; sirtinol promotes the reaction [cudraflavone B results in increased expression of BAX protein]
resveratrol inhibits the reaction [cudraflavone B results in decreased expression of BCL2 protein]; sirtinol promotes the reaction [cudraflavone B results in decreased expression of BCL2 protein]
cudraflavone B results in increased activity of CASP3 protein resveratrol inhibits the reaction [cudraflavone B results in increased activity of CASP3 protein]; sirtinol promotes the reaction [cudraflavone B results in increased activity of CASP3 protein]
cudraflavone B results in increased expression of CDKN1A protein resveratrol inhibits the reaction [cudraflavone B results in increased expression of CDKN1A protein]; sirtinol promotes the reaction [cudraflavone B results in increased expression of CDKN1A protein]
resveratrol inhibits the reaction [cudraflavone B results in increased expression of CDKN1B protein]; sirtinol promotes the reaction [cudraflavone B results in increased expression of CDKN1B protein]
resveratrol inhibits the reaction [cudraflavone B results in decreased phosphorylation of RB1 protein]; sirtinol promotes the reaction [cudraflavone B results in decreased phosphorylation of RB1 protein]
cudraflavone B results in increased expression of SIRT1 mRNA; cudraflavone B results in increased expression of SIRT1 protein resveratrol promotes the reaction [cudraflavone B results in increased expression of SIRT1 mRNA]; resveratrol promotes the reaction [cudraflavone B results in increased expression of SIRT1 protein]; sirtinol inhibits the reaction [cudraflavone B results in increased expression of SIRT1 mRNA]; sirtinol inhibits the reaction [cudraflavone B results in increased expression of SIRT1 protein]
cudraflavone B results in increased expression of TP53 protein resveratrol inhibits the reaction [cudraflavone B results in increased expression of TP53 protein]; sirtinol promotes the reaction [cudraflavone B results in increased expression of TP53 protein]
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