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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:3-mercaptopropanoic acid
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Accession:CHEBI:44111 term browser browse the term
Definition:A mercaptopropanoic acid that is propanoic acid carrying a sulfanyl group at position 3.
Synonyms:exact_synonym: 3-sulfanylpropanoic acid
 related_synonym: 2-mercaptoethanecarboxylic acid;   3-mercaptopropionic acid;   3-thiohydracrylic acid;   3-thiolpropanoic acid;   3-thiopropanoic acid;   3-thiopropionic acid;   3MPA;   BETA-MERCAPTOPROPIONIC ACID;   Formula=C3H6O2S;   InChI=1S/C3H6O2S/c4-3(5)1-2-6/h6H,1-2H2,(H,4,5);   InChIKey=DKIDEFUBRARXTE-UHFFFAOYSA-N;   SMILES=OC(=O)CCS;   beta-thiopropionic acid
 xref: Beilstein:773807;   CAS:107-96-0;   Gmelin:101294;   HMDB:HMDB0041604
 xref_mesh: MESH:D015097
 xref: MetaCyc:CPD-7673;   PDBeChem:MPT;   PMID:19885720;   PMID:3600189;   Reaxys:773807
 cyclic_relationship: is_conjugate_acid_of CHEBI:86386


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3-mercaptopropanoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp1 caspase 1 multiple interactions ISO [3-Mercaptopropionic Acid co-treated with cadmium telluride] results in increased cleavage of CASP1 protein CTD PMID:29852215 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Cd40 CD40 molecule multiple interactions ISO [3-Mercaptopropionic Acid co-treated with cadmium telluride] results in increased expression of CD40 protein CTD PMID:29852215 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534 		JBrowse link
G Gad1 glutamate decarboxylase 1 decreases activity
multiple interactions		 EXP
ISO		 3-Mercaptopropionic Acid results in decreased activity of GAD1 protein
3-Mercaptopropionic Acid binds to and results in decreased activity of GAD1 protein		 CTD PMID:4154755 PMID:35151785 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gad2 glutamate decarboxylase 2 decreases activity
multiple interactions		 EXP
ISO		 3-Mercaptopropionic Acid results in decreased activity of GAD2 protein
3-Mercaptopropionic Acid binds to and results in decreased activity of GAD2 protein		 CTD PMID:4154755 PMID:35151785 NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [3-Mercaptopropionic Acid co-treated with cadmium telluride] results in increased expression of and results in increased secretion of IL1B protein; [3-Mercaptopropionic Acid co-treated with cadmium telluride] results in increased expression of IL1B mRNA CTD PMID:29852215 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Itgam integrin subunit alpha M multiple interactions ISO [3-Mercaptopropionic Acid co-treated with cadmium telluride] results in increased expression of ITGAM protein CTD PMID:29852215 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions ISO [3-Mercaptopropionic Acid co-treated with cadmium telluride] results in increased expression of MYD88 protein CTD PMID:29852215 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO [3-Mercaptopropionic Acid co-treated with cadmium telluride] results in decreased expression of and results in increased phosphorylation of NFKBIA protein CTD PMID:29852215 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO [3-Mercaptopropionic Acid co-treated with cadmium telluride] results in increased expression of NLRP3 mRNA; [3-Mercaptopropionic Acid co-treated with cadmium telluride] results in increased expression of NLRP3 protein CTD PMID:29852215 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Pycard PYD and CARD domain containing multiple interactions ISO [3-Mercaptopropionic Acid co-treated with cadmium telluride] results in increased expression of PYCARD mRNA CTD PMID:29852215 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G S100a9 S100 calcium binding protein A9 multiple interactions ISO [3-Mercaptopropionic Acid co-treated with cadmium telluride] results in increased expression of S100A9 mRNA CTD PMID:29852215 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G Tlr2 toll-like receptor 2 multiple interactions ISO [3-Mercaptopropionic Acid co-treated with cadmium telluride] results in increased expression of TLR2 protein CTD PMID:29852215 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [3-Mercaptopropionic Acid co-treated with cadmium telluride] results in increased expression of TNF mRNA CTD PMID:29852215 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19848
    role 19824
      biological role 19822
        biochemical role 19533
          metabolite 19519
            eukaryotic metabolite 19342
              algal metabolite 16141
                3-mercaptopropanoic acid 13
Path 2
Term Annotations click to browse term
  CHEBI ontology 19848
    subatomic particle 19846
      composite particle 19846
        hadron 19846
          baryon 19846
            nucleon 19846
              atomic nucleus 19846
                atom 19846
                  main group element atom 19796
                    p-block element atom 19796
                      carbon group element atom 19741
                        carbon atom 19737
                          organic molecular entity 19737
                            heteroorganic entity 19495
                              organochalcogen compound 19257
                                organooxygen compound 19175
                                  carbon oxoacid 18641
                                    carboxylic acid 18638
                                      monocarboxylic acid 18006
                                        fatty acid 16810
                                          saturated fatty acid 16535
                                            propionic acid 3803
                                              mercaptopropanoic acid 13
                                                3-mercaptopropanoic acid 13
paths to the root