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G |
Aldh2 |
aldehyde dehydrogenase 2 family member |
multiple interactions |
ISO |
molinate inhibits the reaction [ALDH2 protein results in increased metabolism of propionaldehyde]; molinate metabolite binds to and results in decreased activity of ALDH2 protein; molinate metabolite inhibits the reaction [ALDH2 protein results in increased metabolism of propionaldehyde] |
CTD |
PMID:20954713 |
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NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
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G |
Lhb |
luteinizing hormone subunit beta |
affects secretion |
EXP |
molinate affects the secretion of LHB protein |
CTD |
PMID:15601673 |
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NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
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G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
increases activity |
ISO |
molinate results in increased activity of NR1I3 protein |
CTD |
PMID:28927721 |
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NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
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G |
Tp53 |
tumor protein p53 |
affects activity |
ISO |
molinate metabolite affects the activity of TP53 protein |
CTD |
PMID:35435491 |
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NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Uba1 |
ubiquitin-like modifier activating enzyme 1 |
multiple interactions |
ISO |
molinate results in increased activity of and results in increased ubiquitination of UBA1 protein |
CTD |
PMID:25714994 |
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NCBI chr X:1,508,700...1,530,677
Ensembl chr X:1,508,666...1,530,636
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G |
Ache |
acetylcholinesterase |
decreases activity |
EXP |
benthiocarb results in decreased activity of ACHE protein |
CTD |
PMID:2775302 PMID:8440873 |
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NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
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G |
Ar |
androgen receptor |
multiple interactions |
ISO |
Dihydrotestosterone inhibits the reaction [benthiocarb results in increased activity of AR protein] |
CTD |
PMID:15064155 |
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NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
multiple interactions |
ISO |
benthiocarb binds to and results in increased activity of NR1I2 protein |
CTD |
PMID:21115097 |
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NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
increases activity |
ISO |
benthiocarb results in increased activity of NR1I3 protein |
CTD |
PMID:28927721 |
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NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
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G |
Tp53 |
tumor protein p53 |
affects activity |
ISO |
benthiocarb metabolite affects the activity of TP53 protein |
CTD |
PMID:35435491 |
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NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Gli1 |
GLI family zinc finger 1 |
multiple interactions |
ISO |
Tolnaftate inhibits the reaction [SHH protein results in increased expression of GLI1 mRNA] |
CTD |
PMID:20434536 |
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NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251
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G |
Gstp1 |
glutathione S-transferase pi 1 |
multiple interactions |
ISO |
Tolnaftate inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] |
CTD |
PMID:23769903 |
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NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
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G |
Il4 |
interleukin 4 |
multiple interactions decreases secretion decreases expression |
ISO |
1-Methyl-3-isobutylxanthine inhibits the reaction [Tolnaftate results in decreased expression of IL4 mRNA]; 1-Methyl-3-isobutylxanthine inhibits the reaction [Tolnaftate results in decreased secretion of IL4 protein]; Bucladesine inhibits the reaction [Tolnaftate results in decreased expression of IL4 mRNA]; Bucladesine inhibits the reaction [Tolnaftate results in decreased secretion of IL4 protein]; Colforsin inhibits the reaction [Tolnaftate results in decreased expression of IL4 mRNA]; Colforsin inhibits the reaction [Tolnaftate results in decreased secretion of IL4 protein] |
CTD |
PMID:11886533 PMID:15284827 |
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NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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G |
Il5 |
interleukin 5 |
multiple interactions decreases expression decreases secretion |
ISO |
1-Methyl-3-isobutylxanthine inhibits the reaction [Tolnaftate results in decreased expression of IL5 mRNA]; 1-Methyl-3-isobutylxanthine inhibits the reaction [Tolnaftate results in decreased secretion of IL5 protein]; Bucladesine inhibits the reaction [Tolnaftate results in decreased expression of IL5 mRNA]; Bucladesine inhibits the reaction [Tolnaftate results in decreased secretion of IL5 protein]; Colforsin inhibits the reaction [Tolnaftate results in decreased expression of IL5 mRNA]; Colforsin inhibits the reaction [Tolnaftate results in decreased secretion of IL5 protein] |
CTD |
PMID:11886533 PMID:15284827 |
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NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
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G |
Shh |
sonic hedgehog signaling molecule |
multiple interactions |
ISO |
Tolnaftate inhibits the reaction [SHH protein results in increased expression of GLI1 mRNA] |
CTD |
PMID:20434536 |
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NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
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